Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 167040063

GI number: 167040063

Start: 1458219

End: 1459289

Strand: Direct

Name: aroB [H]

Synonym: Teth514_1423

Alternate gene names: 167040063

Gene position: 1458219-1459289 (Clockwise)

Preceding gene: 167040062

Following gene: 167040064

Centisome position: 59.34

GC content: 31.37

Gene sequence:

>1071_bases
TTGGATTTTATAACAATTGATTTAAAAGAAAGGTCTTATCCTATTTATTTTGCCTATGATTCTTTTGATAAATTAGGAGA
AATAGTAAAGAAACATGTAAGAAGTAGTAAAACATTTATAATAACTGATTTTAATGTTTATCCTTTGTATTTTGAAAAAC
TCAATGAAAGTCTTAAAAAAAGTCGTTTTGATGTGTCATATGAAGTTATTCCTGCAGGGGAAACAAGTAAAACAATGGAA
ATGGCACAAAGACTTCTTGAAAAAGCTTATGATAGTGGACTTTTAAGAGACAGTTCAGTTATAGCTCTTGGAGGAGGCGT
TGTAGGAGACATAGCTGGATTTGTCGCAGCAACTTACATGAGGGGAATAGACTTTGTGCAAATTCCCACAACCTTATTGG
CTCAGGTTGATAGTAGTGTTGGTGGCAAAGTAGCAGTCAATCTAAAAAAAGGCAAAAACATAGTAGGAGCTTTTCATCAG
CCTAAAATGGTATATATAGACGCTGCTGTTTTAAACACGTTAGATAAAAGAGAGATACTTGGAGGATTAGCTGAGATAAT
CAAATATGGAATTATATGGGATTTTGATTTATTTGAATACATCGAAAATAACCTGCATGAAATTTTAGATTTAAAAGAAG
ACAAATTAAAACATATAGTCAAAAAATCTTGTGAAATAAAAGGGAAAATCGTATCCCTTGATGAAAAAGAGGAAAACCTA
CGTTCAATATTAAATTTTGGCCATACCATAGGGCATGCCATTGAAGCTTTGACCGGTTATGAGTGGTATATTCATGGAGA
AGCAGTCGCTATAGGGATGGTATACGCTTGTAAACTTGCTCTAAATTTAGGATATATTGATGAAAAATATTTTGAAAGGA
TTTTTTCTTTAATACAAAGGACAGGATTACCCACAGATTATGAGGATTTGCATAAAGAAGACATTATAAAAGCTATAAAA
CTTGACAAAAAAAATAGAAGCAGCAAAATAAATTTTGTTCTTCCTTGTGGTTTTGGAAAAGTTGAAGTCATAAGTGTTAG
AGAAGAAGAAATTTTAAAGGTTTTAAAATAA

Upstream 100 bases:

>100_bases
CAGAAGAAGTTTAAGCTGAAATATTGTTTTACTCATTTTGCTTAACTTTTTCTTTTTAATGATGTATAATATTAAAATAA
AAAAGTGTGAGGTGTGAACT

Downstream 100 bases:

>100_bases
GCGGGTAACCGCTTTTTTCTTTATCTTTTTTAGACTTTATGAAAAATTTACTTGACTTTACTTATGCAAAGTATTAAAAT
ATCACCAATATTATAAATTG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MDFITIDLKERSYPIYFAYDSFDKLGEIVKKHVRSSKTFIITDFNVYPLYFEKLNESLKKSRFDVSYEVIPAGETSKTME
MAQRLLEKAYDSGLLRDSSVIALGGGVVGDIAGFVAATYMRGIDFVQIPTTLLAQVDSSVGGKVAVNLKKGKNIVGAFHQ
PKMVYIDAAVLNTLDKREILGGLAEIIKYGIIWDFDLFEYIENNLHEILDLKEDKLKHIVKKSCEIKGKIVSLDEKEENL
RSILNFGHTIGHAIEALTGYEWYIHGEAVAIGMVYACKLALNLGYIDEKYFERIFSLIQRTGLPTDYEDLHKEDIIKAIK
LDKKNRSSKINFVLPCGFGKVEVISVREEEILKVLK

Sequences:

>Translated_356_residues
MDFITIDLKERSYPIYFAYDSFDKLGEIVKKHVRSSKTFIITDFNVYPLYFEKLNESLKKSRFDVSYEVIPAGETSKTME
MAQRLLEKAYDSGLLRDSSVIALGGGVVGDIAGFVAATYMRGIDFVQIPTTLLAQVDSSVGGKVAVNLKKGKNIVGAFHQ
PKMVYIDAAVLNTLDKREILGGLAEIIKYGIIWDFDLFEYIENNLHEILDLKEDKLKHIVKKSCEIKGKIVSLDEKEENL
RSILNFGHTIGHAIEALTGYEWYIHGEAVAIGMVYACKLALNLGYIDEKYFERIFSLIQRTGLPTDYEDLHKEDIIKAIK
LDKKNRSSKINFVLPCGFGKVEVISVREEEILKVLK
>Mature_356_residues
MDFITIDLKERSYPIYFAYDSFDKLGEIVKKHVRSSKTFIITDFNVYPLYFEKLNESLKKSRFDVSYEVIPAGETSKTME
MAQRLLEKAYDSGLLRDSSVIALGGGVVGDIAGFVAATYMRGIDFVQIPTTLLAQVDSSVGGKVAVNLKKGKNIVGAFHQ
PKMVYIDAAVLNTLDKREILGGLAEIIKYGIIWDFDLFEYIENNLHEILDLKEDKLKHIVKKSCEIKGKIVSLDEKEENL
RSILNFGHTIGHAIEALTGYEWYIHGEAVAIGMVYACKLALNLGYIDEKYFERIFSLIQRTGLPTDYEDLHKEDIIKAIK
LDKKNRSSKINFVLPCGFGKVEVISVREEEILKVLK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=353, Percent_Identity=40.5099150141643, Blast_Score=269, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6320332, Length=370, Percent_Identity=37.5675675675676, Blast_Score=222, Evalue=6e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40300; Mature: 40300

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFITIDLKERSYPIYFAYDSFDKLGEIVKKHVRSSKTFIITDFNVYPLYFEKLNESLKK
CCEEEEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHH
SRFDVSYEVIPAGETSKTMEMAQRLLEKAYDSGLLRDSSVIALGGGVVGDIAGFVAATYM
HHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHH
RGIDFVQIPTTLLAQVDSSVGGKVAVNLKKGKNIVGAFHQPKMVYIDAAVLNTLDKREIL
HCCCEEEHHHHHHHHHHCCCCCEEEEEEECCCCEEECCCCCCEEEEEHHHHHHHHHHHHH
GGLAEIIKYGIIWDFDLFEYIENNLHEILDLKEDKLKHIVKKSCEIKGKIVSLDEKEENL
HHHHHHHHHCCEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCHHHHH
RSILNFGHTIGHAIEALTGYEWYIHGEAVAIGMVYACKLALNLGYIDEKYFERIFSLIQR
HHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TGLPTDYEDLHKEDIIKAIKLDKKNRSSKINFVLPCGFGKVEVISVREEEILKVLK
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECHHHHHHHCC
>Mature Secondary Structure
MDFITIDLKERSYPIYFAYDSFDKLGEIVKKHVRSSKTFIITDFNVYPLYFEKLNESLKK
CCEEEEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHH
SRFDVSYEVIPAGETSKTMEMAQRLLEKAYDSGLLRDSSVIALGGGVVGDIAGFVAATYM
HHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHH
RGIDFVQIPTTLLAQVDSSVGGKVAVNLKKGKNIVGAFHQPKMVYIDAAVLNTLDKREIL
HCCCEEEHHHHHHHHHHCCCCCEEEEEEECCCCEEECCCCCCEEEEEHHHHHHHHHHHHH
GGLAEIIKYGIIWDFDLFEYIENNLHEILDLKEDKLKHIVKKSCEIKGKIVSLDEKEENL
HHHHHHHHHCCEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCHHHHH
RSILNFGHTIGHAIEALTGYEWYIHGEAVAIGMVYACKLALNLGYIDEKYFERIFSLIQR
HHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TGLPTDYEDLHKEDIIKAIKLDKKNRSSKINFVLPCGFGKVEVISVREEEILKVLK
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA