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The map label for this gene is arsC [H]

Identifier: 167040054

GI number: 167040054

Start: 1450143

End: 1450580

Strand: Reverse

Name: arsC [H]

Synonym: Teth514_1414

Alternate gene names: 167040054

Gene position: 1450580-1450143 (Counterclockwise)

Preceding gene: 167040070

Following gene: 167040051

Centisome position: 59.03

GC content: 32.42

Gene sequence:

>438_bases
GTGTCAAAAAATAAAAAAATTTTGTATTTTATATGTACTGGCAATTCCTGTAGAAGTCAAATGGCAGAAGGTTTTGGCAA
ATATTATGGAAAAGATGATTTTGAAGTATATAGTGGTGGTGTAGAAGCTCACGGTTTAAACCCAAAAGCTGTACAAGTTA
TGAAGGAAATAGGAATTGACATAAGCAATCAAACTTCCGATTTATTGGATGAAAATATCCTTTTTAAAGCAGATTATGTG
ATAACTTTATGTGGTGATGCAAGAGATAAATGTCCTGCTTTGCCTCCTTCAATAAAAAGCCTCCATTGGGACTTAGAAGA
CCCTGCAAGAGCAACAGGCACAGAAGAAGAAGTTTTAAATAAATTTCGTGAAATAAGAGATATAATCAAAGAAAATGTAA
AAAATTTGATAGAAGACATAAAAAAGCACTCGCACTAA

Upstream 100 bases:

>100_bases
TACTCAAAAGAATTTAACATATTCTTAACAAAAAGCGGATTGTTTTATAATCTACAATCATTTATAATAATTTGTGAATA
AACAAAAAGGGGGATGTTAC

Downstream 100 bases:

>100_bases
TCACGAGTGCTTTTAAATTATAAAATTCCAGCCTCTTCATGTTTTTTCACTATTTCTTCAGCTAACTTATCAAGAGCCTT
AAAGTCTTCTTCTTTTGGGA

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MSKNKKILYFICTGNSCRSQMAEGFGKYYGKDDFEVYSGGVEAHGLNPKAVQVMKEIGIDISNQTSDLLDENILFKADYV
ITLCGDARDKCPALPPSIKSLHWDLEDPARATGTEEEVLNKFREIRDIIKENVKNLIEDIKKHSH

Sequences:

>Translated_145_residues
MSKNKKILYFICTGNSCRSQMAEGFGKYYGKDDFEVYSGGVEAHGLNPKAVQVMKEIGIDISNQTSDLLDENILFKADYV
ITLCGDARDKCPALPPSIKSLHWDLEDPARATGTEEEVLNKFREIRDIIKENVKNLIEDIKKHSH
>Mature_144_residues
SKNKKILYFICTGNSCRSQMAEGFGKYYGKDDFEVYSGGVEAHGLNPKAVQVMKEIGIDISNQTSDLLDENILFKADYVI
TLCGDARDKCPALPPSIKSLHWDLEDPARATGTEEEVLNKFREIRDIIKENVKNLIEDIKKHSH

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16366; Mature: 16235

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNKKILYFICTGNSCRSQMAEGFGKYYGKDDFEVYSGGVEAHGLNPKAVQVMKEIGID
CCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHCCC
ISNQTSDLLDENILFKADYVITLCGDARDKCPALPPSIKSLHWDLEDPARATGTEEEVLN
CCCCHHHHHHCCCEEECCEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHH
KFREIRDIIKENVKNLIEDIKKHSH
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKNKKILYFICTGNSCRSQMAEGFGKYYGKDDFEVYSGGVEAHGLNPKAVQVMKEIGID
CCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHCCC
ISNQTSDLLDENILFKADYVITLCGDARDKCPALPPSIKSLHWDLEDPARATGTEEEVLN
CCCCHHHHHHCCCEEECCEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHH
KFREIRDIIKENVKNLIEDIKKHSH
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA