Click here to switch to the map view.

The map label for this gene is rnr [H]

Identifier: 167039994

GI number: 167039994

Start: 1389938

End: 1392106

Strand: Direct

Name: rnr [H]

Synonym: Teth514_1353

Alternate gene names: 167039994

Gene position: 1389938-1392106 (Clockwise)

Preceding gene: 167039993

Following gene: 167039995

Centisome position: 56.56

GC content: 33.24

Gene sequence:

>2169_bases
ATGGGAATGAGCGTAAAAGAAAGACTTTTAGAATTAATGAGAGAAGAGAATTATAAACCTTCTAAAATAGAAGAAATAAT
GAAAATATTAGGGATAGACTATAGTCAAAAAAGCATTTTAGAAAAAATATTAAAAGAGATGGAAAAAGAAGGCCTTGTTT
TTAAAACAAAACGAGGTAAATATGCTCTTCCTGAAAGATTAGATTTAGTAAAAGGTAAGATTGAATTTCATTCAAGAGGC
TATGGCTTTTTAATTCCCGAAGATAGCAATATAAAGGACATATTCATACCTGTAAGTGGCATGAACGGTGCAATGCATGA
CGATACTGTTTTAGTGAGAGTTACAAAAAGGGTGGATGGAAAGAGCGAAGAAGGAGAAGTTGTAAAAATTCTCAAAAGGG
CAAATACAACTATTGTTGGAACTTACGAAAAAAGCAAAAATTTTGGCTTTGTAGTGCCAGACAACAAAAAGATCCATCAA
GATATATTTATTCCTAAAGGAGAAGATAAAGGCGCTAAAACAGGCATGAAAGTTGTAGCCAGAATTACTAAATGGCCTGA
AGGAAGGCGAAGTCCTGAAGGGGAGATTATAGAAGTATTAGGATACAAAGGTGACCCTGGCATAGATGTAATGTCTATAA
TACGGGCGTATGATATTCCTGAAGTTTTTCCTAAAGAGGTTTTAAAAGAAGCAGAAGAGATACCGACAGAAATTCCTGAA
GAAGAGAAAAAGAGAAGAGTTGATTTGACTGATTTAGATTTTGTCACAATTGATGGAGAAGATGCAAAAGATTTGGACGA
TGCAGTATGTGTACAAAAACTTCAAGATGGCAATTATCTTCTGTATGTGAGTATTGCAGATGTGAGCCATTATGTGAAAG
AAGGTTTGAATTTAGATAAAGAAGCATTAAAAAGAGGTTGTAGTGTATATTTCATTGATAGAGTAATACCAATGTTGCCA
CCTAAGTTATCTAATGGTATTTGCAGTCTAAATCCGCAGGAAGAAAGACTGACTCTCACTGTTAAAATGAAAATAAACTC
TCAAGGAGAAGTTGTAGACCATGAAATTTTTGAAAGCATTATAAAAAGCAAAGAGAGAATGACATATACAAATGTTTACA
AACTTTTAGAAGAAAATGATGAAGAATTAAAAAAGAGGTATCAGTACCTATTGGAAGATTTTAAACTAATGAAAGAGCTA
GCTCTTGTTTTGCTAGAGAAAAGGAAAAGAAGAGGCAGTGTAGATTTTGATTTTCCTGAAGCTAAAGTAATAGTAGACGA
GAAAGGTAAACCAATAGATGTTGTAAAAGTCGAAAGGAATATAGCTCATAGGATAATTGAAGAATTTATGTTAGTAGCTA
ATGAAACGGTAGCTGAGCATATGCATTGGGTAAATGTACCATTTGTTTATAGAATACACGAACATCCGGATATAGAGAAA
TTAATTGCTTTCAATAAATTTATTCACAATTTGGGATACCATATAAAAGGAATTGAAGGAGGACAAATACATCCAAAGTC
TTTGCAAGAGTTAATAAGACAAGTGAGAGGAAAGAGTGAGCAAAGAGTTGTAGAAACTTTGCTTTTAAGGTCTTTAAAAA
GAGCAAGATACAGTCCAGAAGACATTGGCCATTATGCTTTGGCGACCCAATATTATACTCACTTTACTTCCCCCATAAGG
CGATATCCTGACCTTATAATTCATAGGATAATCAAAGAATACATAAATGGAAAATTAACAAAAAAAAGGCAACGCCATTA
CAACAGAATTTTAAATGACATTGCTTTAAAATCTTCTGAGAGAGAAAGAGCAGCAGAAGCTGCAGAAAGAGAAATAGAAG
AATTAAAGAAAGTAGAGTACATGGCAGATAGAATAGGGAATGTTTATAAAGGGATAATTTCCAACGTGACAAATTACGGA
TTTTTTGTAGAACTTGACAACACTGTGGAAGGGTTAGTAGATGTTGCTTCATTGGAGGATGACTATTACCATTTTGATCC
AGAAAGATATGTTTTAATTGGTGAAAAGAGCAAAAAAGTTTACTCTATAGGTAAAGAGGTTTATGTAAAAGTTGTTCATG
TAGATGTGGATAGGAGAGAAATAGACTTTGTTTTAGCAGAAGAAGAAAAAGATAATTTAGAGATTGGCTTAACCGAGCAT
AAAAGCTGA

Upstream 100 bases:

>100_bases
AATCAAAACTTGTGAAGAATTTGGAATTTCTTTAGACGAATTTTTAGAGATTGCTCTTAATGAAATGAAAAAAATCGCAC
CACAGATAGGATTGTGAGGA

Downstream 100 bases:

>100_bases
AACATATATTGACACTATTTAAAAATGTGTTATAATATAATAGCGATGAGGGTGCCCTATTTGTGACACACAAGTAGGGC
AATTTTCTCCTAAAGAGGGT

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 722; Mature: 721

Protein sequence:

>722_residues
MGMSVKERLLELMREENYKPSKIEEIMKILGIDYSQKSILEKILKEMEKEGLVFKTKRGKYALPERLDLVKGKIEFHSRG
YGFLIPEDSNIKDIFIPVSGMNGAMHDDTVLVRVTKRVDGKSEEGEVVKILKRANTTIVGTYEKSKNFGFVVPDNKKIHQ
DIFIPKGEDKGAKTGMKVVARITKWPEGRRSPEGEIIEVLGYKGDPGIDVMSIIRAYDIPEVFPKEVLKEAEEIPTEIPE
EEKKRRVDLTDLDFVTIDGEDAKDLDDAVCVQKLQDGNYLLYVSIADVSHYVKEGLNLDKEALKRGCSVYFIDRVIPMLP
PKLSNGICSLNPQEERLTLTVKMKINSQGEVVDHEIFESIIKSKERMTYTNVYKLLEENDEELKKRYQYLLEDFKLMKEL
ALVLLEKRKRRGSVDFDFPEAKVIVDEKGKPIDVVKVERNIAHRIIEEFMLVANETVAEHMHWVNVPFVYRIHEHPDIEK
LIAFNKFIHNLGYHIKGIEGGQIHPKSLQELIRQVRGKSEQRVVETLLLRSLKRARYSPEDIGHYALATQYYTHFTSPIR
RYPDLIIHRIIKEYINGKLTKKRQRHYNRILNDIALKSSERERAAEAAEREIEELKKVEYMADRIGNVYKGIISNVTNYG
FFVELDNTVEGLVDVASLEDDYYHFDPERYVLIGEKSKKVYSIGKEVYVKVVHVDVDRREIDFVLAEEEKDNLEIGLTEH
KS

Sequences:

>Translated_722_residues
MGMSVKERLLELMREENYKPSKIEEIMKILGIDYSQKSILEKILKEMEKEGLVFKTKRGKYALPERLDLVKGKIEFHSRG
YGFLIPEDSNIKDIFIPVSGMNGAMHDDTVLVRVTKRVDGKSEEGEVVKILKRANTTIVGTYEKSKNFGFVVPDNKKIHQ
DIFIPKGEDKGAKTGMKVVARITKWPEGRRSPEGEIIEVLGYKGDPGIDVMSIIRAYDIPEVFPKEVLKEAEEIPTEIPE
EEKKRRVDLTDLDFVTIDGEDAKDLDDAVCVQKLQDGNYLLYVSIADVSHYVKEGLNLDKEALKRGCSVYFIDRVIPMLP
PKLSNGICSLNPQEERLTLTVKMKINSQGEVVDHEIFESIIKSKERMTYTNVYKLLEENDEELKKRYQYLLEDFKLMKEL
ALVLLEKRKRRGSVDFDFPEAKVIVDEKGKPIDVVKVERNIAHRIIEEFMLVANETVAEHMHWVNVPFVYRIHEHPDIEK
LIAFNKFIHNLGYHIKGIEGGQIHPKSLQELIRQVRGKSEQRVVETLLLRSLKRARYSPEDIGHYALATQYYTHFTSPIR
RYPDLIIHRIIKEYINGKLTKKRQRHYNRILNDIALKSSERERAAEAAEREIEELKKVEYMADRIGNVYKGIISNVTNYG
FFVELDNTVEGLVDVASLEDDYYHFDPERYVLIGEKSKKVYSIGKEVYVKVVHVDVDRREIDFVLAEEEKDNLEIGLTEH
KS
>Mature_721_residues
GMSVKERLLELMREENYKPSKIEEIMKILGIDYSQKSILEKILKEMEKEGLVFKTKRGKYALPERLDLVKGKIEFHSRGY
GFLIPEDSNIKDIFIPVSGMNGAMHDDTVLVRVTKRVDGKSEEGEVVKILKRANTTIVGTYEKSKNFGFVVPDNKKIHQD
IFIPKGEDKGAKTGMKVVARITKWPEGRRSPEGEIIEVLGYKGDPGIDVMSIIRAYDIPEVFPKEVLKEAEEIPTEIPEE
EKKRRVDLTDLDFVTIDGEDAKDLDDAVCVQKLQDGNYLLYVSIADVSHYVKEGLNLDKEALKRGCSVYFIDRVIPMLPP
KLSNGICSLNPQEERLTLTVKMKINSQGEVVDHEIFESIIKSKERMTYTNVYKLLEENDEELKKRYQYLLEDFKLMKELA
LVLLEKRKRRGSVDFDFPEAKVIVDEKGKPIDVVKVERNIAHRIIEEFMLVANETVAEHMHWVNVPFVYRIHEHPDIEKL
IAFNKFIHNLGYHIKGIEGGQIHPKSLQELIRQVRGKSEQRVVETLLLRSLKRARYSPEDIGHYALATQYYTHFTSPIRR
YPDLIIHRIIKEYINGKLTKKRQRHYNRILNDIALKSSERERAAEAAEREIEELKKVEYMADRIGNVYKGIISNVTNYGF
FVELDNTVEGLVDVASLEDDYYHFDPERYVLIGEKSKKVYSIGKEVYVKVVHVDVDRREIDFVLAEEEKDNLEIGLTEHK
S

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=509, Percent_Identity=29.2730844793713, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI190014623, Length=509, Percent_Identity=29.2730844793713, Blast_Score=198, Evalue=2e-50,
Organism=Homo sapiens, GI134288890, Length=419, Percent_Identity=30.3102625298329, Blast_Score=189, Evalue=7e-48,
Organism=Homo sapiens, GI19115966, Length=488, Percent_Identity=27.0491803278689, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI219521928, Length=488, Percent_Identity=27.0491803278689, Blast_Score=152, Evalue=2e-36,
Organism=Escherichia coli, GI87082383, Length=709, Percent_Identity=39.6332863187588, Blast_Score=513, Evalue=1e-146,
Organism=Escherichia coli, GI1787542, Length=647, Percent_Identity=27.6661514683153, Blast_Score=195, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI212645896, Length=487, Percent_Identity=29.3634496919918, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17553506, Length=425, Percent_Identity=30.8235294117647, Blast_Score=172, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6324552, Length=556, Percent_Identity=28.5971223021583, Blast_Score=173, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6320499, Length=425, Percent_Identity=27.7647058823529, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6323943, Length=431, Percent_Identity=24.3619489559165, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24649634, Length=486, Percent_Identity=29.4238683127572, Blast_Score=205, Evalue=7e-53,
Organism=Drosophila melanogaster, GI19922976, Length=469, Percent_Identity=27.9317697228145, Blast_Score=166, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24654597, Length=469, Percent_Identity=27.9317697228145, Blast_Score=166, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24654592, Length=469, Percent_Identity=27.9317697228145, Blast_Score=166, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 83592; Mature: 83461

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMSVKERLLELMREENYKPSKIEEIMKILGIDYSQKSILEKILKEMEKEGLVFKTKRGK
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEECCCC
YALPERLDLVKGKIEFHSRGYGFLIPEDSNIKDIFIPVSGMNGAMHDDTVLVRVTKRVDG
CCCCHHHHHHHCCEEEECCCEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEEEECCCC
KSEEGEVVKILKRANTTIVGTYEKSKNFGFVVPDNKKIHQDIFIPKGEDKGAKTGMKVVA
CCCCCHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCHHHCCCCCCCCCCCHHHHHHHHH
RITKWPEGRRSPEGEIIEVLGYKGDPGIDVMSIIRAYDIPEVFPKEVLKEAEEIPTEIPE
HHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCC
EEKKRRVDLTDLDFVTIDGEDAKDLDDAVCVQKLQDGNYLLYVSIADVSHYVKEGLNLDK
HHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCCCH
EALKRGCSVYFIDRVIPMLPPKLSNGICSLNPQEERLTLTVKMKINSQGEVVDHEIFESI
HHHHCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHH
IKSKERMTYTNVYKLLEENDEELKKRYQYLLEDFKLMKELALVLLEKRKRRGSVDFDFPE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AKVIVDEKGKPIDVVKVERNIAHRIIEEFMLVANETVAEHMHWVNVPFVYRIHEHPDIEK
CEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHH
LIAFNKFIHNLGYHIKGIEGGQIHPKSLQELIRQVRGKSEQRVVETLLLRSLKRARYSPE
HHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHH
DIGHYALATQYYTHFTSPIRRYPDLIIHRIIKEYINGKLTKKRQRHYNRILNDIALKSSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCH
RERAAEAAEREIEELKKVEYMADRIGNVYKGIISNVTNYGFFVELDNTVEGLVDVASLED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCC
DYYHFDPERYVLIGEKSKKVYSIGKEVYVKVVHVDVDRREIDFVLAEEEKDNLEIGLTEH
CCEEECCCEEEEEECCCCHHHHCCHHHEEEEEEEECCCCEEEEEEECCCCCCCEEEECCC
KS
CC
>Mature Secondary Structure 
GMSVKERLLELMREENYKPSKIEEIMKILGIDYSQKSILEKILKEMEKEGLVFKTKRGK
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEECCCC
YALPERLDLVKGKIEFHSRGYGFLIPEDSNIKDIFIPVSGMNGAMHDDTVLVRVTKRVDG
CCCCHHHHHHHCCEEEECCCEEEEECCCCCCCEEEEEECCCCCCCCCCEEEEEEEECCCC
KSEEGEVVKILKRANTTIVGTYEKSKNFGFVVPDNKKIHQDIFIPKGEDKGAKTGMKVVA
CCCCCHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCHHHCCCCCCCCCCCHHHHHHHHH
RITKWPEGRRSPEGEIIEVLGYKGDPGIDVMSIIRAYDIPEVFPKEVLKEAEEIPTEIPE
HHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCC
EEKKRRVDLTDLDFVTIDGEDAKDLDDAVCVQKLQDGNYLLYVSIADVSHYVKEGLNLDK
HHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCCCH
EALKRGCSVYFIDRVIPMLPPKLSNGICSLNPQEERLTLTVKMKINSQGEVVDHEIFESI
HHHHCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHH
IKSKERMTYTNVYKLLEENDEELKKRYQYLLEDFKLMKELALVLLEKRKRRGSVDFDFPE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AKVIVDEKGKPIDVVKVERNIAHRIIEEFMLVANETVAEHMHWVNVPFVYRIHEHPDIEK
CEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHH
LIAFNKFIHNLGYHIKGIEGGQIHPKSLQELIRQVRGKSEQRVVETLLLRSLKRARYSPE
HHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHH
DIGHYALATQYYTHFTSPIRRYPDLIIHRIIKEYINGKLTKKRQRHYNRILNDIALKSSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCH
RERAAEAAEREIEELKKVEYMADRIGNVYKGIISNVTNYGFFVELDNTVEGLVDVASLED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCC
DYYHFDPERYVLIGEKSKKVYSIGKEVYVKVVHVDVDRREIDFVLAEEEKDNLEIGLTEH
CCEEECCCEEEEEECCCCHHHHCCHHHEEEEEEEECCCCEEEEEEECCCCCCCEEEECCC
KS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]