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The map label for this gene is pgk [H]

Identifier: 167039950

GI number: 167039950

Start: 1343884

End: 1345065

Strand: Direct

Name: pgk [H]

Synonym: Teth514_1307

Alternate gene names: 167039950

Gene position: 1343884-1345065 (Clockwise)

Preceding gene: 167039949

Following gene: 167039951

Centisome position: 54.69

GC content: 38.16

Gene sequence:

>1182_bases
ATGAAAAAAACTGTGCGGGATATAGATGTGGCGGGAAAAAGAGTGCTGGTAAGGGTAGACTTTAATGTGCCTATGGATGA
AAATAAAAATATAACAGATGACACTCGTATAAAAGCAGCACTGCCCACCATTCAATATCTCATAAACAATAACGCAAAAG
TAATACTTGTATCCCATTTAGGAAGGCCAAAAGGGAAAGTAAATCCAGAATATTCTTTAAAACCTGTGGCAAAGAGGTTA
TCTGAACTTTTAGGTAAGCAAGTTTCTATGGCAGAGGATGTAATTGGAGAGGATGCAAAAGCGAAAGCAGCCGCATTAAA
AGAAGGCGAAGTATTGCTCTTAGAAAATGTGAGATTCCATGCAGAGGAAGAGAAAAATGACCCTCAATTTGCAAAAGAAT
TAGCTTCTTTAGCAGATATATATGTAAATGACGCTTTTGGTACGGCTCACAGAGCTCATGCTTCAACAGCAGGGGTGGCA
GCGTATTTACCAGCAGTATCAGGCTTTTTAATTGAAAAAGAACTTACAATCATGGGAGAAGCTCTTGAAAACCCAAAAAG
ACCTTTTGTTGCAATATTGGGAGGAGCTAAAGTTTCTGACAAAATAGGGGTTATAACAAACCTATTAGAAAAAGTAGATA
GCCTTTTAATTGGCGGTGGTATGGCTTACACCTTTATAAAAGCAAAAGGATATGAAATTGGTAAGTCGCTTTTAGAAGAG
GATAAAATAGAGTTAGCTAAAGAATTAATGGAGAAGGCTAAGCAAAAGGGTGTTAATTTGATGCTTCCTGTTGATACAGT
TATTGCTAAAGAATTGAAATCAGGCGTACCTTATGAAGTAGTCGATATAGACAAAATGCCTCAAGACCAAATAGGAGTAG
ACATTGGACCTAAGACTATTGAAGAATACTCAAAAGTGATAAAACACGCGATGACAGTAGTGTGGAATGGGCCTATGGGA
GTTTTTGAAATTCCTGAGTTTGCAAAAGGTACAGAGGCTATTGCGAAAGCTTTGAGTGAATGCAAAGGTATTACTATAGT
AGGCGGCGGTGATTCTGCAGCTGCTATAGAGCAATTAGGATATGCGGATAAAGTCACTCATATTTCTACTGGAGGAGGAG
CTTCTCTAGAGTTTTTGGAAGGCAAAGTGTTGCCGGGAATTGAAGTTTTAAATGACAAGTAA

Upstream 100 bases:

>100_bases
AGACCTTGCAAAATATATTGCTGAGAGACTCTAAGTAGTAAAAGGTCCGTGTCCTTTTATGGACCGGACCTTTAAATCCT
AGTATAAGGAGGTTTTTGTG

Downstream 100 bases:

>100_bases
AGGGGTGTTTGTTTTGAGAAGACCAATAATTGCAGGTAATTGGAAAATGCACATGACCCCTTCTGAAGCGGTGAAATTAG
TTGATGAATTGATACCTCAA

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKKTVRDIDVAGKRVLVRVDFNVPMDENKNITDDTRIKAALPTIQYLINNNAKVILVSHLGRPKGKVNPEYSLKPVAKRL
SELLGKQVSMAEDVIGEDAKAKAAALKEGEVLLLENVRFHAEEEKNDPQFAKELASLADIYVNDAFGTAHRAHASTAGVA
AYLPAVSGFLIEKELTIMGEALENPKRPFVAILGGAKVSDKIGVITNLLEKVDSLLIGGGMAYTFIKAKGYEIGKSLLEE
DKIELAKELMEKAKQKGVNLMLPVDTVIAKELKSGVPYEVVDIDKMPQDQIGVDIGPKTIEEYSKVIKHAMTVVWNGPMG
VFEIPEFAKGTEAIAKALSECKGITIVGGGDSAAAIEQLGYADKVTHISTGGGASLEFLEGKVLPGIEVLNDK

Sequences:

>Translated_393_residues
MKKTVRDIDVAGKRVLVRVDFNVPMDENKNITDDTRIKAALPTIQYLINNNAKVILVSHLGRPKGKVNPEYSLKPVAKRL
SELLGKQVSMAEDVIGEDAKAKAAALKEGEVLLLENVRFHAEEEKNDPQFAKELASLADIYVNDAFGTAHRAHASTAGVA
AYLPAVSGFLIEKELTIMGEALENPKRPFVAILGGAKVSDKIGVITNLLEKVDSLLIGGGMAYTFIKAKGYEIGKSLLEE
DKIELAKELMEKAKQKGVNLMLPVDTVIAKELKSGVPYEVVDIDKMPQDQIGVDIGPKTIEEYSKVIKHAMTVVWNGPMG
VFEIPEFAKGTEAIAKALSECKGITIVGGGDSAAAIEQLGYADKVTHISTGGGASLEFLEGKVLPGIEVLNDK
>Mature_393_residues
MKKTVRDIDVAGKRVLVRVDFNVPMDENKNITDDTRIKAALPTIQYLINNNAKVILVSHLGRPKGKVNPEYSLKPVAKRL
SELLGKQVSMAEDVIGEDAKAKAAALKEGEVLLLENVRFHAEEEKNDPQFAKELASLADIYVNDAFGTAHRAHASTAGVA
AYLPAVSGFLIEKELTIMGEALENPKRPFVAILGGAKVSDKIGVITNLLEKVDSLLIGGGMAYTFIKAKGYEIGKSLLEE
DKIELAKELMEKAKQKGVNLMLPVDTVIAKELKSGVPYEVVDIDKMPQDQIGVDIGPKTIEEYSKVIKHAMTVVWNGPMG
VFEIPEFAKGTEAIAKALSECKGITIVGGGDSAAAIEQLGYADKVTHISTGGGASLEFLEGKVLPGIEVLNDK

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=416, Percent_Identity=48.5576923076923, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI31543397, Length=416, Percent_Identity=48.5576923076923, Blast_Score=365, Evalue=1e-101,
Organism=Escherichia coli, GI1789294, Length=390, Percent_Identity=44.8717948717949, Blast_Score=338, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI17508823, Length=411, Percent_Identity=48.9051094890511, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6319857, Length=413, Percent_Identity=49.8789346246973, Blast_Score=374, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24581203, Length=414, Percent_Identity=47.3429951690821, Blast_Score=359, Evalue=2e-99,
Organism=Drosophila melanogaster, GI17136394, Length=410, Percent_Identity=46.0975609756098, Blast_Score=341, Evalue=5e-94,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 42330; Mature: 42330

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTVRDIDVAGKRVLVRVDFNVPMDENKNITDDTRIKAALPTIQYLINNNAKVILVSHL
CCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECC
GRPKGKVNPEYSLKPVAKRLSELLGKQVSMAEDVIGEDAKAKAAALKEGEVLLLENVRFH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCEEC
AEEEKNDPQFAKELASLADIYVNDAFGTAHRAHASTAGVAAYLPAVSGFLIEKELTIMGE
CCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALENPKRPFVAILGGAKVSDKIGVITNLLEKVDSLLIGGGMAYTFIKAKGYEIGKSLLEE
HHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHH
DKIELAKELMEKAKQKGVNLMLPVDTVIAKELKSGVPYEVVDIDKMPQDQIGVDIGPKTI
HHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHCCCCEEEEECCCCCHHHCCCCCCHHHH
EEYSKVIKHAMTVVWNGPMGVFEIPEFAKGTEAIAKALSECKGITIVGGGDSAAAIEQLG
HHHHHHHHHHHHEEECCCCCCEECCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHCC
YADKVTHISTGGGASLEFLEGKVLPGIEVLNDK
CHHHEEEEECCCCCEEHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKTVRDIDVAGKRVLVRVDFNVPMDENKNITDDTRIKAALPTIQYLINNNAKVILVSHL
CCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECC
GRPKGKVNPEYSLKPVAKRLSELLGKQVSMAEDVIGEDAKAKAAALKEGEVLLLENVRFH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCEEC
AEEEKNDPQFAKELASLADIYVNDAFGTAHRAHASTAGVAAYLPAVSGFLIEKELTIMGE
CCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ALENPKRPFVAILGGAKVSDKIGVITNLLEKVDSLLIGGGMAYTFIKAKGYEIGKSLLEE
HHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHH
DKIELAKELMEKAKQKGVNLMLPVDTVIAKELKSGVPYEVVDIDKMPQDQIGVDIGPKTI
HHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHCCCCEEEEECCCCCHHHCCCCCCHHHH
EEYSKVIKHAMTVVWNGPMGVFEIPEFAKGTEAIAKALSECKGITIVGGGDSAAAIEQLG
HHHHHHHHHHHHEEECCCCCCEECCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHCC
YADKVTHISTGGGASLEFLEGKVLPGIEVLNDK
CHHHEEEEECCCCCEEHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]