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The map label for this gene is gap [H]

Identifier: 167039949

GI number: 167039949

Start: 1342810

End: 1343817

Strand: Direct

Name: gap [H]

Synonym: Teth514_1306

Alternate gene names: 167039949

Gene position: 1342810-1343817 (Clockwise)

Preceding gene: 167039948

Following gene: 167039950

Centisome position: 54.65

GC content: 35.42

Gene sequence:

>1008_bases
ATGGGTGTTAAAGTTGCTATTAATGGTTTTGGAAGAATTGGAAGAAATGTATTCAGAGCTGCATTTAAGAAAAATGTTGA
CCTTGAATTTGTAGCTATCAACGATTTAACAGATGCAAAAACATTGGCTCATCTATTAAAATACGATTCTACTTTTGGTA
AATTTGAAGGAGAAGTATCTTATACGGAGGACGCGTTAATTGTAAATGGCAAAGAAATTAAAATTTTCAAAGAAACTGAT
CCGGCTAAACTTCCTTGGGGAGAATTAGGAGTAGACATTGTAATTGAATCTACAGGAAGATTTACAAACAAAGATGATGC
TATAAAGCACATCCATGCTGGAGCGAAAAAAGTTATAATTTCTGCGCCTGCTAAAAATGAGGACATAACAATTGTTATGG
GCGTTAATGAAAACATGTATGACCCAGCTAACCATCATGTAATTTCAAATGCTTCTTGTACAACCAACTGCTTAGCACCA
ATAGCTAAAGTAATTAATGATAAATTCCGTATTAAAAAAGGTATGATGACAACAGTTCACTCTTACACCAATGACCAGAG
AATACTTGATTTACCTCACAAGGATTTGAGAAGGGCGAGGTCTGCTGCTATGTCAATAATACCTACTACAACTGGTGCAG
CAAAGGCTATTCACTTAGTAATTCCTGAATTAAAAGGAAAAATGAATGGTTTTGCGATGAGGGTTCCAACTCCAGACGTA
TCTGTTGTTGATCTTGTTGCAGAAGTTGAAGTACCTGTTACAGTTGAAGAGGTTAATGCAGCATTAAAAGAAGCTTCTGA
AACATATATGAAAGGCATTTTAGGTTATTCTGAAGAGCCATTAGTTTCAATGGACTATAAAGGTGACGATAGGTCTTCTA
TAGTTGATGCACCACTTACAATGGTAATTGAAGGAACATTAGTAAAAGTTGTTTCTTGGTATGACAATGAATGGGGTTAC
TCCAACAGAGTTGTAGACCTTGCAAAATATATTGCTGAGAGACTCTAA

Upstream 100 bases:

>100_bases
AGTGCTTGTCACTGATGAAGGAGCTGCATTTGAGATTTTAAAAATTGTTTAAAACACCTTTTCAGGTGTTTATAAAATAA
AAATCAAGGAGGAATACATA

Downstream 100 bases:

>100_bases
GTAGTAAAAGGTCCGTGTCCTTTTATGGACCGGACCTTTAAATCCTAGTATAAGGAGGTTTTTGTGATGAAAAAAACTGT
GCGGGATATAGATGTGGCGG

Product: type I glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MGVKVAINGFGRIGRNVFRAAFKKNVDLEFVAINDLTDAKTLAHLLKYDSTFGKFEGEVSYTEDALIVNGKEIKIFKETD
PAKLPWGELGVDIVIESTGRFTNKDDAIKHIHAGAKKVIISAPAKNEDITIVMGVNENMYDPANHHVISNASCTTNCLAP
IAKVINDKFRIKKGMMTTVHSYTNDQRILDLPHKDLRRARSAAMSIIPTTTGAAKAIHLVIPELKGKMNGFAMRVPTPDV
SVVDLVAEVEVPVTVEEVNAALKEASETYMKGILGYSEEPLVSMDYKGDDRSSIVDAPLTMVIEGTLVKVVSWYDNEWGY
SNRVVDLAKYIAERL

Sequences:

>Translated_335_residues
MGVKVAINGFGRIGRNVFRAAFKKNVDLEFVAINDLTDAKTLAHLLKYDSTFGKFEGEVSYTEDALIVNGKEIKIFKETD
PAKLPWGELGVDIVIESTGRFTNKDDAIKHIHAGAKKVIISAPAKNEDITIVMGVNENMYDPANHHVISNASCTTNCLAP
IAKVINDKFRIKKGMMTTVHSYTNDQRILDLPHKDLRRARSAAMSIIPTTTGAAKAIHLVIPELKGKMNGFAMRVPTPDV
SVVDLVAEVEVPVTVEEVNAALKEASETYMKGILGYSEEPLVSMDYKGDDRSSIVDAPLTMVIEGTLVKVVSWYDNEWGY
SNRVVDLAKYIAERL
>Mature_334_residues
GVKVAINGFGRIGRNVFRAAFKKNVDLEFVAINDLTDAKTLAHLLKYDSTFGKFEGEVSYTEDALIVNGKEIKIFKETDP
AKLPWGELGVDIVIESTGRFTNKDDAIKHIHAGAKKVIISAPAKNEDITIVMGVNENMYDPANHHVISNASCTTNCLAPI
AKVINDKFRIKKGMMTTVHSYTNDQRILDLPHKDLRRARSAAMSIIPTTTGAAKAIHLVIPELKGKMNGFAMRVPTPDVS
VVDLVAEVEVPVTVEEVNAALKEASETYMKGILGYSEEPLVSMDYKGDDRSSIVDAPLTMVIEGTLVKVVSWYDNEWGYS
NRVVDLAKYIAERL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=332, Percent_Identity=49.3975903614458, Blast_Score=328, Evalue=4e-90,
Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=50.8982035928144, Blast_Score=327, Evalue=8e-90,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=54.1916167664671, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=45.2887537993921, Blast_Score=303, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI17534677, Length=337, Percent_Identity=53.4124629080119, Blast_Score=342, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17534679, Length=337, Percent_Identity=53.4124629080119, Blast_Score=342, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=52.5222551928783, Blast_Score=334, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=52.5222551928783, Blast_Score=334, Evalue=5e-92,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=51.3513513513513, Blast_Score=344, Evalue=1e-95,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=52.8528528528528, Blast_Score=343, Evalue=2e-95,
Organism=Saccharomyces cerevisiae, GI6321631, Length=333, Percent_Identity=53.1531531531532, Blast_Score=343, Evalue=3e-95,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=51.0510510510511, Blast_Score=327, Evalue=6e-90,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=51.0510510510511, Blast_Score=327, Evalue=6e-90,
Organism=Drosophila melanogaster, GI17933600, Length=333, Percent_Identity=50.1501501501502, Blast_Score=325, Evalue=2e-89,
Organism=Drosophila melanogaster, GI18110149, Length=333, Percent_Identity=50.1501501501502, Blast_Score=325, Evalue=2e-89,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=49.0853658536585, Blast_Score=315, Evalue=2e-86,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36899; Mature: 36768

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVKVAINGFGRIGRNVFRAAFKKNVDLEFVAINDLTDAKTLAHLLKYDSTFGKFEGEVS
CCEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEE
YTEDALIVNGKEIKIFKETDPAKLPWGELGVDIVIESTGRFTNKDDAIKHIHAGAKKVII
ECCCEEEECCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCEEEE
SAPAKNEDITIVMGVNENMYDPANHHVISNASCTTNCLAPIAKVINDKFRIKKGMMTTVH
ECCCCCCCEEEEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHH
SYTNDQRILDLPHKDLRRARSAAMSIIPTTTGAAKAIHLVIPELKGKMNGFAMRVPTPDV
HCCCCCEEEECCHHHHHHHHHHHEEEEECCCCCHHEEEEEEHHHCCCCCCEEEECCCCCC
SVVDLVAEVEVPVTVEEVNAALKEASETYMKGILGYSEEPLVSMDYKGDDRSSIVDAPLT
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHCCCCEE
MVIEGTLVKVVSWYDNEWGYSNRVVDLAKYIAERL
EEECHHHEEEEEHHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
GVKVAINGFGRIGRNVFRAAFKKNVDLEFVAINDLTDAKTLAHLLKYDSTFGKFEGEVS
CEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEE
YTEDALIVNGKEIKIFKETDPAKLPWGELGVDIVIESTGRFTNKDDAIKHIHAGAKKVII
ECCCEEEECCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCEEEE
SAPAKNEDITIVMGVNENMYDPANHHVISNASCTTNCLAPIAKVINDKFRIKKGMMTTVH
ECCCCCCCEEEEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHH
SYTNDQRILDLPHKDLRRARSAAMSIIPTTTGAAKAIHLVIPELKGKMNGFAMRVPTPDV
HCCCCCEEEECCHHHHHHHHHHHEEEEECCCCCHHEEEEEEHHHCCCCCCEEEECCCCCC
SVVDLVAEVEVPVTVEEVNAALKEASETYMKGILGYSEEPLVSMDYKGDDRSSIVDAPLT
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHCCCCEE
MVIEGTLVKVVSWYDNEWGYSNRVVDLAKYIAERL
EEECHHHEEEEEHHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2684782; 2227448; 2656407; 7408868; 193030; 3586018; 9175858 [H]