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The map label for this gene is malZ [C]

Identifier: 167039832

GI number: 167039832

Start: 1223420

End: 1225144

Strand: Direct

Name: malZ [C]

Synonym: Teth514_1187

Alternate gene names: 167039832

Gene position: 1223420-1225144 (Clockwise)

Preceding gene: 167039831

Following gene: 167039833

Centisome position: 49.79

GC content: 33.97

Gene sequence:

>1725_bases
ATGATAAAAGAAGCTATATTTCATAAAAGCGATATGCCTTACGCATATCCACTGAATGAAAATCAATTAAAGATAGTACT
AAGGACGGCTGTATTTGATGTAGATAGGGTGTATGTTTTATACAAAGACAGATACGATTGGCTGGGAAAATTCAAAATAA
AACCAATGGTATTAACTCATACCAACGAGTTATTTGATTATTATGAGACTACTTTAGAGCTTAATAAAAAATTTGTGTAT
TTTTTCTATTTGGTATCTGATGGGGGCGAGAAGTTATATTATACAGAAGCAGGATTTTACAAAAAAAGGCCAGAAAATCA
TTTTTGGGGATTTTTCCATTACCCGTATATAGGAGAAAAGGATGTCTTTTTTGCTCCAGAGTGGACAAGCGATTGCATAG
TGTATCAGATATTTCCTGAAAGGTTTAATAACGGTGACAAATCAAATGACCCTGAAAGTGTAAAGCCTTGGGGTGAAAAA
CCTACTGCAGATTCTTTCTTTGGAGGAGATTTGCAAGGAATAATAGATAAAATAGATTATTTAAAGGATTTGGGTATAAA
TGCTATTTATTTAACCCCCATATTTTTATCGCCTTCTACTCACAAATATGATACCACTGATTATTATACAATTGACCCCC
ACTTTGGTGATACGCAAAAAGCGAGAGAACTTGTGCAAAAATGTCATGACAATGGCATAAAAGTTATATTTGATGCCGTT
TTTAATCACTGTGGATATGATTTTTTTGCATTTCAGGATGTTATTAAAAATGGTAAAAAATCAAAATACTGGAATTGGTT
TAATATATACGAATGTCCACTTAAAACTCATCCAAAACCATCATATGAAGCTTTTGCAGATACTGTATGGAGAATGCCAA
AACTTATGACAAAAAATCCAGAAGTACAGAAGTATTTATTGGAAGTAGCGGAATATTGGATTAAAGAAGTGGACATAGAC
GGCTGGAGGCTGGATGTTGCTAATGAGATAGACCACCATTTTTGGAGAAAGTTTAGAGAAGTTGTAAAGGCAGCTAAACC
GGAGGCCATAATTGTAGGAGAGGTTTGGCATGATGCTTCTCCTTGGCTTAGAGGGGATCAGTTTGACAGTGTAATGAACT
ATCCTTTTAGAAATGCGGTTGTAGACTTTTTTGCAGAAAGGAAAATAAGTGCTTCTCGCTTTAATACAATGATTACAGAG
CAACTTATGAGGCATATGGATAGTGTAAATAGGGTTATGTTTAATTTAATAGGAAGTCATGATACTGAAAGGTTTTTGAC
TTTAGCTAATGGCATGGTTGCGAGAATGAAGTTAGCGTTGGTGTTTCAATTTACCTTTGTTGGAATTCCATATATTTATT
ATGGAGACGAGGTAGGAATGGTAGGGGGGTATGACCCTGATTGTAGAAGATGCATGATATGGGAGGAGGAAAAGCAAAAT
AAAAGTATTTTTAATTTCTATAAAAAGCTGATTTCTATAAGGAGAGAAAATGAGGAGCTCAAATACGGAAGTTTCTGTAC
TTTATACGCTATAGGAAGGGTATTTGCTTTTAAGAGGGAATACAAAGGTAAATCAATAATTGTTGTACTAAATAACAGTA
GCAAGCAGGAAGTGATATTTTTGAATGAAGTAGAAGGAAAAGAAGATATTTTAAAGATGAAGGAATTAAAAAGGAGTGGA
AATCTCCTTTACTTGCAACCTAACTCTGCCTATATTTTAAAGTAA

Upstream 100 bases:

>100_bases
CCGCCAGCTGTTAAAATAACTGTAGATGGTGAGGAGCTACCAACAGTGCAAACACCGTCACCAGTTACAATAAATATACA
TACATAGAAAGGGGAAAGAG

Downstream 100 bases:

>100_bases
CCAATCTGAGTTTAAGTGAATAATATGAAGATAGAAAAATATAGGGGAATTAAAATTCCCCTATATTTTTTAAAAAAAAC
AGGGGTGATGGTATGAAAGA

Product: alpha amylase catalytic subunit

Products: NA

Alternate protein names: CDase; Cyclomaltodextrin hydrolase, decycling [H]

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MIKEAIFHKSDMPYAYPLNENQLKIVLRTAVFDVDRVYVLYKDRYDWLGKFKIKPMVLTHTNELFDYYETTLELNKKFVY
FFYLVSDGGEKLYYTEAGFYKKRPENHFWGFFHYPYIGEKDVFFAPEWTSDCIVYQIFPERFNNGDKSNDPESVKPWGEK
PTADSFFGGDLQGIIDKIDYLKDLGINAIYLTPIFLSPSTHKYDTTDYYTIDPHFGDTQKARELVQKCHDNGIKVIFDAV
FNHCGYDFFAFQDVIKNGKKSKYWNWFNIYECPLKTHPKPSYEAFADTVWRMPKLMTKNPEVQKYLLEVAEYWIKEVDID
GWRLDVANEIDHHFWRKFREVVKAAKPEAIIVGEVWHDASPWLRGDQFDSVMNYPFRNAVVDFFAERKISASRFNTMITE
QLMRHMDSVNRVMFNLIGSHDTERFLTLANGMVARMKLALVFQFTFVGIPYIYYGDEVGMVGGYDPDCRRCMIWEEEKQN
KSIFNFYKKLISIRRENEELKYGSFCTLYAIGRVFAFKREYKGKSIIVVLNNSSKQEVIFLNEVEGKEDILKMKELKRSG
NLLYLQPNSAYILK

Sequences:

>Translated_574_residues
MIKEAIFHKSDMPYAYPLNENQLKIVLRTAVFDVDRVYVLYKDRYDWLGKFKIKPMVLTHTNELFDYYETTLELNKKFVY
FFYLVSDGGEKLYYTEAGFYKKRPENHFWGFFHYPYIGEKDVFFAPEWTSDCIVYQIFPERFNNGDKSNDPESVKPWGEK
PTADSFFGGDLQGIIDKIDYLKDLGINAIYLTPIFLSPSTHKYDTTDYYTIDPHFGDTQKARELVQKCHDNGIKVIFDAV
FNHCGYDFFAFQDVIKNGKKSKYWNWFNIYECPLKTHPKPSYEAFADTVWRMPKLMTKNPEVQKYLLEVAEYWIKEVDID
GWRLDVANEIDHHFWRKFREVVKAAKPEAIIVGEVWHDASPWLRGDQFDSVMNYPFRNAVVDFFAERKISASRFNTMITE
QLMRHMDSVNRVMFNLIGSHDTERFLTLANGMVARMKLALVFQFTFVGIPYIYYGDEVGMVGGYDPDCRRCMIWEEEKQN
KSIFNFYKKLISIRRENEELKYGSFCTLYAIGRVFAFKREYKGKSIIVVLNNSSKQEVIFLNEVEGKEDILKMKELKRSG
NLLYLQPNSAYILK
>Mature_574_residues
MIKEAIFHKSDMPYAYPLNENQLKIVLRTAVFDVDRVYVLYKDRYDWLGKFKIKPMVLTHTNELFDYYETTLELNKKFVY
FFYLVSDGGEKLYYTEAGFYKKRPENHFWGFFHYPYIGEKDVFFAPEWTSDCIVYQIFPERFNNGDKSNDPESVKPWGEK
PTADSFFGGDLQGIIDKIDYLKDLGINAIYLTPIFLSPSTHKYDTTDYYTIDPHFGDTQKARELVQKCHDNGIKVIFDAV
FNHCGYDFFAFQDVIKNGKKSKYWNWFNIYECPLKTHPKPSYEAFADTVWRMPKLMTKNPEVQKYLLEVAEYWIKEVDID
GWRLDVANEIDHHFWRKFREVVKAAKPEAIIVGEVWHDASPWLRGDQFDSVMNYPFRNAVVDFFAERKISASRFNTMITE
QLMRHMDSVNRVMFNLIGSHDTERFLTLANGMVARMKLALVFQFTFVGIPYIYYGDEVGMVGGYDPDCRRCMIWEEEKQN
KSIFNFYKKLISIRRENEELKYGSFCTLYAIGRVFAFKREYKGKSIIVVLNNSSKQEVIFLNEVEGKEDILKMKELKRSG
NLLYLQPNSAYILK

Specific function: Hydrolyzes cyclodextrins. Can also act on linear maltodextrins, with the exception of maltose [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=535, Percent_Identity=22.803738317757, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1786604, Length=507, Percent_Identity=33.1360946745562, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1790687, Length=428, Percent_Identity=25, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789995, Length=502, Percent_Identity=21.9123505976096, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322245, Length=230, Percent_Identity=28.2608695652174, Blast_Score=90, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6321726, Length=393, Percent_Identity=23.4096692111959, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322241, Length=395, Percent_Identity=24.8101265822785, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322021, Length=395, Percent_Identity=24.8101265822785, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324416, Length=395, Percent_Identity=24.5569620253165, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6321731, Length=405, Percent_Identity=22.962962962963, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319776, Length=225, Percent_Identity=28, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24583747, Length=543, Percent_Identity=24.4935543278085, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24583749, Length=543, Percent_Identity=24.4935543278085, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24586587, Length=228, Percent_Identity=29.8245614035088, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24583745, Length=541, Percent_Identity=24.3992606284658, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221330053, Length=221, Percent_Identity=28.9592760180996, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24586599, Length=581, Percent_Identity=21.342512908778, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24586597, Length=537, Percent_Identity=21.9739292364991, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24586591, Length=408, Percent_Identity=22.7941176470588, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24586593, Length=240, Percent_Identity=26.25, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45549022, Length=121, Percent_Identity=34.7107438016529, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24586589, Length=215, Percent_Identity=27.4418604651163, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR004185
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF02903 Alpha-amylase_N [H]

EC number: =3.2.1.54 [H]

Molecular weight: Translated: 67872; Mature: 67872

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKEAIFHKSDMPYAYPLNENQLKIVLRTAVFDVDRVYVLYKDRYDWLGKFKIKPMVLTH
CCCHHHHCCCCCCEEECCCCCCEEEEEEEHHHCCCEEEEEEECCCCCCCEEEECEEEEEC
TNELFDYYETTLELNKKFVYFFYLVSDGGEKLYYTEAGFYKKRPENHFWGFFHYPYIGEK
CHHHHHHHHHHHHHCCEEEEEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCC
DVFFAPEWTSDCIVYQIFPERFNNGDKSNDPESVKPWGEKPTADSFFGGDLQGIIDKIDY
CEEECCCCCCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LKDLGINAIYLTPIFLSPSTHKYDTTDYYTIDPHFGDTQKARELVQKCHDNGIKVIFDAV
HHHCCCCEEEEEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEHHHHH
FNHCGYDFFAFQDVIKNGKKSKYWNWFNIYECPLKTHPKPSYEAFADTVWRMPKLMTKNP
HHHCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCH
EVQKYLLEVAEYWIKEVDIDGWRLDVANEIDHHFWRKFREVVKAAKPEAIIVGEVWHDAS
HHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
PWLRGDQFDSVMNYPFRNAVVDFFAERKISASRFNTMITEQLMRHMDSVNRVMFNLIGSH
CCCCCCCHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DTERFLTLANGMVARMKLALVFQFTFVGIPYIYYGDEVGMVGGYDPDCRRCMIWEEEKQN
CHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCEEEEECHHHCC
KSIFNFYKKLISIRRENEELKYGSFCTLYAIGRVFAFKREYKGKSIIVVLNNSSKQEVIF
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEE
LNEVEGKEDILKMKELKRSGNLLYLQPNSAYILK
EECCCCHHHHHHHHHHHHCCCEEEECCCCCEEEC
>Mature Secondary Structure
MIKEAIFHKSDMPYAYPLNENQLKIVLRTAVFDVDRVYVLYKDRYDWLGKFKIKPMVLTH
CCCHHHHCCCCCCEEECCCCCCEEEEEEEHHHCCCEEEEEEECCCCCCCEEEECEEEEEC
TNELFDYYETTLELNKKFVYFFYLVSDGGEKLYYTEAGFYKKRPENHFWGFFHYPYIGEK
CHHHHHHHHHHHHHCCEEEEEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCC
DVFFAPEWTSDCIVYQIFPERFNNGDKSNDPESVKPWGEKPTADSFFGGDLQGIIDKIDY
CEEECCCCCCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LKDLGINAIYLTPIFLSPSTHKYDTTDYYTIDPHFGDTQKARELVQKCHDNGIKVIFDAV
HHHCCCCEEEEEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEHHHHH
FNHCGYDFFAFQDVIKNGKKSKYWNWFNIYECPLKTHPKPSYEAFADTVWRMPKLMTKNP
HHHCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCH
EVQKYLLEVAEYWIKEVDIDGWRLDVANEIDHHFWRKFREVVKAAKPEAIIVGEVWHDAS
HHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
PWLRGDQFDSVMNYPFRNAVVDFFAERKISASRFNTMITEQLMRHMDSVNRVMFNLIGSH
CCCCCCCHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DTERFLTLANGMVARMKLALVFQFTFVGIPYIYYGDEVGMVGGYDPDCRRCMIWEEEKQN
CHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCEEEEECHHHCC
KSIFNFYKKLISIRRENEELKYGSFCTLYAIGRVFAFKREYKGKSIIVVLNNSSKQEVIF
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEE
LNEVEGKEDILKMKELKRSGNLLYLQPNSAYILK
EECCCCHHHHHHHHHHHHCCCEEEECCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1644767; 8425614 [H]