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The map label for this gene is galE [H]

Identifier: 167039737

GI number: 167039737

Start: 1124179

End: 1125168

Strand: Direct

Name: galE [H]

Synonym: Teth514_1088

Alternate gene names: 167039737

Gene position: 1124179-1125168 (Clockwise)

Preceding gene: 167039736

Following gene: 167039738

Centisome position: 45.75

GC content: 40.2

Gene sequence:

>990_bases
ATGGCGGTTTTAGTATGCGGTGGTGCAGGTTATATTGGAAGCCACACAGTTGCAGCACTTTTAAGGAGAAATGAAGAAGT
TGTCGTTGTAGATAACCTCGTCACAGGGCATAAGGAATCTGTTTTGGGAGGAAAACTGTATATAGGTGATTTAAGGGATG
AAGCCTTTTTAGACAAGGTATTTATAGAAAATGAAATTGAAGCGGTAATTGATTTTGCAGCTTTTTCACTTGTGGGAGAA
AGTGTAGAGGAGCCATTTAAATATTATGAAAACAACGTATGCGGGACATTGAGCCTTTTAAAAGCGATGAAGAAACACAA
TGTCAACAAAATCGTGTTTTCTTCAACAGCTGCAACATATGGAGAACCAGAGAGAATTCCAATAGAAGAGGAAGATAGAA
CTAATCCCACAAGCCCTTATGGTGAGACAAAGCTTGCCGTTGAAAAGATGCTAAAATGGGCAGACAGTGCTTATGGAATC
AAATACGTCGCTTTGCGATATTTTAACGTTGCAGGGGCTATTGAAACAGGCGAGATTGGAGAGGACCATTCGCCTGAGAC
GCACCTTATACCGATTATACTTCAGGTTGCACTTGGGAAAAGAGAAAAGATAATGATTTATGGTGATGATTATCCTACTA
AAGATGGGACATGTATAAGAGATTATATTCACGTGATGGACTTAGCTGATGCACATATACTTGCGTTGGATAAATTGAGA
AAAGACAATAATAGCGCAATTTATAACCTGGGAAATGGAGAAGGTTTTAGTGTAAAGGAAGTGATAGAAGTTGCAAGAAA
AGTGACAGGGCATCCTATTCCAGCAGAAGTTGCTGGGCGCCGTCCGGGAGACCCTGCAGTACTTGTGGCATCTTCCAAAA
AGGCAATAGAAGAGTTAGGTTGGGTGCCAAAACATCCATCTTTAGAAGAAATAATTGAAAGTGCTTGGATGTGGCACAAA
AATCATCCAAATGGCTTTAAGAGAGGGTAA

Upstream 100 bases:

>100_bases
ACTCACAATTACACTCAAAAAATAGGCTACAGGCCAACAGTCTATATAACGGGAATAGGTGAAGGAGCAGGAGAAATTAA
ATACTGAAGGAGGTAAAAAT

Downstream 100 bases:

>100_bases
AGGAAGGGGTATAAATGGAAAACTTAATACCAGTCAGCTACAAATTGTTAAAAGGAATGAACGAATCAGTTATATTAAAT
ATCATAAGAAAAATGGGACC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MAVLVCGGAGYIGSHTVAALLRRNEEVVVVDNLVTGHKESVLGGKLYIGDLRDEAFLDKVFIENEIEAVIDFAAFSLVGE
SVEEPFKYYENNVCGTLSLLKAMKKHNVNKIVFSSTAATYGEPERIPIEEEDRTNPTSPYGETKLAVEKMLKWADSAYGI
KYVALRYFNVAGAIETGEIGEDHSPETHLIPIILQVALGKREKIMIYGDDYPTKDGTCIRDYIHVMDLADAHILALDKLR
KDNNSAIYNLGNGEGFSVKEVIEVARKVTGHPIPAEVAGRRPGDPAVLVASSKKAIEELGWVPKHPSLEEIIESAWMWHK
NHPNGFKRG

Sequences:

>Translated_329_residues
MAVLVCGGAGYIGSHTVAALLRRNEEVVVVDNLVTGHKESVLGGKLYIGDLRDEAFLDKVFIENEIEAVIDFAAFSLVGE
SVEEPFKYYENNVCGTLSLLKAMKKHNVNKIVFSSTAATYGEPERIPIEEEDRTNPTSPYGETKLAVEKMLKWADSAYGI
KYVALRYFNVAGAIETGEIGEDHSPETHLIPIILQVALGKREKIMIYGDDYPTKDGTCIRDYIHVMDLADAHILALDKLR
KDNNSAIYNLGNGEGFSVKEVIEVARKVTGHPIPAEVAGRRPGDPAVLVASSKKAIEELGWVPKHPSLEEIIESAWMWHK
NHPNGFKRG
>Mature_328_residues
AVLVCGGAGYIGSHTVAALLRRNEEVVVVDNLVTGHKESVLGGKLYIGDLRDEAFLDKVFIENEIEAVIDFAAFSLVGES
VEEPFKYYENNVCGTLSLLKAMKKHNVNKIVFSSTAATYGEPERIPIEEEDRTNPTSPYGETKLAVEKMLKWADSAYGIK
YVALRYFNVAGAIETGEIGEDHSPETHLIPIILQVALGKREKIMIYGDDYPTKDGTCIRDYIHVMDLADAHILALDKLRK
DNNSAIYNLGNGEGFSVKEVIEVARKVTGHPIPAEVAGRRPGDPAVLVASSKKAIEELGWVPKHPSLEEIIESAWMWHKN
HPNGFKRG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=42.5655976676385, Blast_Score=259, Evalue=3e-69,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=42.5655976676385, Blast_Score=259, Evalue=3e-69,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=42.5655976676385, Blast_Score=259, Evalue=3e-69,
Organism=Homo sapiens, GI42516563, Length=328, Percent_Identity=28.3536585365854, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI7657641, Length=344, Percent_Identity=27.0348837209302, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=43.9169139465875, Blast_Score=274, Evalue=7e-75,
Organism=Escherichia coli, GI1788353, Length=358, Percent_Identity=27.3743016759777, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI48994969, Length=360, Percent_Identity=25.2777777777778, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790049, Length=290, Percent_Identity=30, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788365, Length=344, Percent_Identity=23.546511627907, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=348, Percent_Identity=41.0919540229885, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI71982038, Length=350, Percent_Identity=40.5714285714286, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17539532, Length=316, Percent_Identity=25.3164556962025, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17568069, Length=303, Percent_Identity=28.3828382838284, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115532424, Length=347, Percent_Identity=24.7838616714697, Blast_Score=71, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=43.8953488372093, Blast_Score=253, Evalue=3e-68,
Organism=Drosophila melanogaster, GI19923002, Length=346, Percent_Identity=42.1965317919075, Blast_Score=257, Evalue=9e-69,
Organism=Drosophila melanogaster, GI21356223, Length=327, Percent_Identity=27.5229357798165, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36318; Mature: 36187

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLVCGGAGYIGSHTVAALLRRNEEVVVVDNLVTGHKESVLGGKLYIGDLRDEAFLDKV
CEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHCCCCEEEEECCCHHHHHHHH
FIENEIEAVIDFAAFSLVGESVEEPFKYYENNVCGTLSLLKAMKKHNVNKIVFSSTAATY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCC
GEPERIPIEEEDRTNPTSPYGETKLAVEKMLKWADSAYGIKYVALRYFNVAGAIETGEIG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCCCC
EDHSPETHLIPIILQVALGKREKIMIYGDDYPTKDGTCIRDYIHVMDLADAHILALDKLR
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
KDNNSAIYNLGNGEGFSVKEVIEVARKVTGHPIPAEVAGRRPGDPAVLVASSKKAIEELG
CCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCEEEEECCHHHHHHCC
WVPKHPSLEEIIESAWMWHKNHPNGFKRG
CCCCCCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AVLVCGGAGYIGSHTVAALLRRNEEVVVVDNLVTGHKESVLGGKLYIGDLRDEAFLDKV
EEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHCCCCEEEEECCCHHHHHHHH
FIENEIEAVIDFAAFSLVGESVEEPFKYYENNVCGTLSLLKAMKKHNVNKIVFSSTAATY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCC
GEPERIPIEEEDRTNPTSPYGETKLAVEKMLKWADSAYGIKYVALRYFNVAGAIETGEIG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCCCC
EDHSPETHLIPIILQVALGKREKIMIYGDDYPTKDGTCIRDYIHVMDLADAHILALDKLR
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
KDNNSAIYNLGNGEGFSVKEVIEVARKVTGHPIPAEVAGRRPGDPAVLVASSKKAIEELG
CCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCEEEEECCHHHHHHCC
WVPKHPSLEEIIESAWMWHKNHPNGFKRG
CCCCCCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]