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The map label for this gene is yqjI [H]

Identifier: 167039731

GI number: 167039731

Start: 1117098

End: 1118504

Strand: Direct

Name: yqjI [H]

Synonym: Teth514_1081

Alternate gene names: 167039731

Gene position: 1117098-1118504 (Clockwise)

Preceding gene: 167039730

Following gene: 167039732

Centisome position: 45.46

GC content: 34.68

Gene sequence:

>1407_bases
ATGAAAGACATTGGATTAATTGGATTGGCAGTAATGGGACAAAATCTTGCTCTAAATATTGCGAGGAAAAAGTATAGTGT
ATCTGTTTTTAACAGGACACCTGATAGAACACAAGAATTTATGAAAAACAAAGTAAAAGACGAAGAAATCGCAGCTTATT
ATGATATCAAGTCTTTTGTAGAATCTTTAAAAAAGCCGCGAAAAATCATCCTCATGGTTAAAGCAGGAAAACCAGTAGAT
GAAATGATTCAAGAACTTTTACCTTATCTAGATAAGGGAGATTTGATTATTGATGGAGGAAATTCCTACTTTAAAGATAC
CTCCAGGAGAATTAATGAATTAAAAGAAAGAGGCATATTGTACCTTGGAATGGGAGTGTCAGGAGGAGAAGCCGGAGCTT
TACACGGGCCTTCTTTGATGCCAGGGGGATCTTACGATGCTTATGAGATGGTAAAAGAAATTCTTTTAAAAATTGCTGCT
CAGACGGAAGCAGGTCCTTGCTGTACATACGTTGGAAATGATTCTGCAGGACACTTTGTCAAAATGGTTCACAACGGTAT
AGAATATGCCATAATGCAAGCAATAGCTGAGGTTTACGATGTACTTCGAAAGGTGTTAAAACTTTCTCCCGAAGAGATAG
GAGAGATATTTGAAAAATGGAATAATGGGGTGTTAAACTCCTTCCTGATGGAAATTTCTTATAAAATAATGAAGTACAAA
GACAAAGAAACAGGAAAATACCTCGTTGACCTCATATTAGACGAAGCAGAACAAAAAGGCACAGGCAAGTGGACTTCTCA
AACTTCTTTGGATTTAGGAATCCCAACTCCTTCTTTAAATCTTGCAGTAGAAGCAAGAACTTTGTCTTTCTTTAAAGAGG
CGAGAGTAGAATTGTCTAAAAAAGTAACAAAAACTTATCCTAGCATTAAGGTGGACAAAGAGAAAGTAATAAATGATTTG
GAGAATGCATTGCTTTTTAGTGTTTTCGTCTCTTTTTCTCAAGGACTATGGCTTATATCTGAGGCTTCAAAGGCTTTTAA
CTATAACATTGACCTTTCAGAAGTTTTAAGAATTTGGAAAGGCGGATGCATCATAAGAGCCAAAATTTTAGATTTCTTAA
GAGACATTATTAAAGAAAATAAAGAAAATGTAAATCTTCTTAACAGTGAAAAGGCGTTATCTTTCTTAATGGATAAAATT
GATTCAATAAAATATATCACTAATTTAACAAAAGATTTTTACCTTCCAACGCTTGTACTTAATTCTTCATTAGATTATTT
CTTGAGCATGATAGAAGAAAACTTGCCTGCTAATCTAATCCAAGCTCAAAGAGATTTCTTCGGTGCTCACACTTACAGAA
GAATAGACAAAGAGGGAATTTTCCACACTGAATGGGAGGCAAACTAA

Upstream 100 bases:

>100_bases
TGGCTTATGACCCTAATCTTTCACCTGAAAACTTTGACAAAAGAACTTAAAAAATTATTTGAACTGCACACTAAATTATA
AAAAACGAGGAGGTAATTAG

Downstream 100 bases:

>100_bases
AACCTAATTGACATCATTTAGTTAATGTTGAATTAATGGGAGTTTTTTGCTCCCCATTTTCTTTCAATAAAAATTCAATA
AAAAAATTTAAAAATCAAGA

Product: 6-phosphogluconate dehydrogenase

Products: NA

Alternate protein names: GNTZII [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKDIGLIGLAVMGQNLALNIARKKYSVSVFNRTPDRTQEFMKNKVKDEEIAAYYDIKSFVESLKKPRKIILMVKAGKPVD
EMIQELLPYLDKGDLIIDGGNSYFKDTSRRINELKERGILYLGMGVSGGEAGALHGPSLMPGGSYDAYEMVKEILLKIAA
QTEAGPCCTYVGNDSAGHFVKMVHNGIEYAIMQAIAEVYDVLRKVLKLSPEEIGEIFEKWNNGVLNSFLMEISYKIMKYK
DKETGKYLVDLILDEAEQKGTGKWTSQTSLDLGIPTPSLNLAVEARTLSFFKEARVELSKKVTKTYPSIKVDKEKVINDL
ENALLFSVFVSFSQGLWLISEASKAFNYNIDLSEVLRIWKGGCIIRAKILDFLRDIIKENKENVNLLNSEKALSFLMDKI
DSIKYITNLTKDFYLPTLVLNSSLDYFLSMIEENLPANLIQAQRDFFGAHTYRRIDKEGIFHTEWEAN

Sequences:

>Translated_468_residues
MKDIGLIGLAVMGQNLALNIARKKYSVSVFNRTPDRTQEFMKNKVKDEEIAAYYDIKSFVESLKKPRKIILMVKAGKPVD
EMIQELLPYLDKGDLIIDGGNSYFKDTSRRINELKERGILYLGMGVSGGEAGALHGPSLMPGGSYDAYEMVKEILLKIAA
QTEAGPCCTYVGNDSAGHFVKMVHNGIEYAIMQAIAEVYDVLRKVLKLSPEEIGEIFEKWNNGVLNSFLMEISYKIMKYK
DKETGKYLVDLILDEAEQKGTGKWTSQTSLDLGIPTPSLNLAVEARTLSFFKEARVELSKKVTKTYPSIKVDKEKVINDL
ENALLFSVFVSFSQGLWLISEASKAFNYNIDLSEVLRIWKGGCIIRAKILDFLRDIIKENKENVNLLNSEKALSFLMDKI
DSIKYITNLTKDFYLPTLVLNSSLDYFLSMIEENLPANLIQAQRDFFGAHTYRRIDKEGIFHTEWEAN
>Mature_468_residues
MKDIGLIGLAVMGQNLALNIARKKYSVSVFNRTPDRTQEFMKNKVKDEEIAAYYDIKSFVESLKKPRKIILMVKAGKPVD
EMIQELLPYLDKGDLIIDGGNSYFKDTSRRINELKERGILYLGMGVSGGEAGALHGPSLMPGGSYDAYEMVKEILLKIAA
QTEAGPCCTYVGNDSAGHFVKMVHNGIEYAIMQAIAEVYDVLRKVLKLSPEEIGEIFEKWNNGVLNSFLMEISYKIMKYK
DKETGKYLVDLILDEAEQKGTGKWTSQTSLDLGIPTPSLNLAVEARTLSFFKEARVELSKKVTKTYPSIKVDKEKVINDL
ENALLFSVFVSFSQGLWLISEASKAFNYNIDLSEVLRIWKGGCIIRAKILDFLRDIIKENKENVNLLNSEKALSFLMDKI
DSIKYITNLTKDFYLPTLVLNSSLDYFLSMIEENLPANLIQAQRDFFGAHTYRRIDKEGIFHTEWEAN

Specific function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH [H]

COG id: COG0362

COG function: function code G; 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=469, Percent_Identity=44.3496801705757, Blast_Score=390, Evalue=1e-108,
Organism=Escherichia coli, GI1788341, Length=465, Percent_Identity=48.6021505376344, Blast_Score=448, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17542558, Length=467, Percent_Identity=43.8972162740899, Blast_Score=416, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6321695, Length=453, Percent_Identity=46.5783664459161, Blast_Score=426, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6321977, Length=453, Percent_Identity=45.6953642384106, Blast_Score=398, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24639279, Length=467, Percent_Identity=43.6830835117773, Blast_Score=375, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR006114
- InterPro:   IPR006113
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR012284
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: =1.1.1.44 [H]

Molecular weight: Translated: 52973; Mature: 52973

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00461 6PGD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDIGLIGLAVMGQNLALNIARKKYSVSVFNRTPDRTQEFMKNKVKDEEIAAYYDIKSFV
CCCCCEEHHHHHCCCCEEEEEHHEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
ESLKKPRKIILMVKAGKPVDEMIQELLPYLDKGDLIIDGGNSYFKDTSRRINELKERGIL
HHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCEE
YLGMGVSGGEAGALHGPSLMPGGSYDAYEMVKEILLKIAAQTEAGPCCTYVGNDSAGHFV
EEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHH
KMVHNGIEYAIMQAIAEVYDVLRKVLKLSPEEIGEIFEKWNNGVLNSFLMEISYKIMKYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
DKETGKYLVDLILDEAEQKGTGKWTSQTSLDLGIPTPSLNLAVEARTLSFFKEARVELSK
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEEHHHHHHHHHHHHHHHH
KVTKTYPSIKVDKEKVINDLENALLFSVFVSFSQGLWLISEASKAFNYNIDLSEVLRIWK
HHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHCCCCCHHHHHHHHC
GGCIIRAKILDFLRDIIKENKENVNLLNSEKALSFLMDKIDSIKYITNLTKDFYLPTLVL
CCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSSLDYFLSMIEENLPANLIQAQRDFFGAHTYRRIDKEGIFHTEWEAN
HCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCC
>Mature Secondary Structure
MKDIGLIGLAVMGQNLALNIARKKYSVSVFNRTPDRTQEFMKNKVKDEEIAAYYDIKSFV
CCCCCEEHHHHHCCCCEEEEEHHEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
ESLKKPRKIILMVKAGKPVDEMIQELLPYLDKGDLIIDGGNSYFKDTSRRINELKERGIL
HHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCEE
YLGMGVSGGEAGALHGPSLMPGGSYDAYEMVKEILLKIAAQTEAGPCCTYVGNDSAGHFV
EEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHH
KMVHNGIEYAIMQAIAEVYDVLRKVLKLSPEEIGEIFEKWNNGVLNSFLMEISYKIMKYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
DKETGKYLVDLILDEAEQKGTGKWTSQTSLDLGIPTPSLNLAVEARTLSFFKEARVELSK
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEEHHHHHHHHHHHHHHHH
KVTKTYPSIKVDKEKVINDLENALLFSVFVSFSQGLWLISEASKAFNYNIDLSEVLRIWK
HHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHCCCCCHHHHHHHHC
GGCIIRAKILDFLRDIIKENKENVNLLNSEKALSFLMDKIDSIKYITNLTKDFYLPTLVL
CCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSSLDYFLSMIEENLPANLIQAQRDFFGAHTYRRIDKEGIFHTEWEAN
HCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10568751; 9298659 [H]