| Definition | Thermoanaerobacter sp. X514 chromosome, complete genome. |
|---|---|
| Accession | NC_010320 |
| Length | 2,457,259 |
Click here to switch to the map view.
The map label for this gene is uvrA [H]
Identifier: 167039703
GI number: 167039703
Start: 1087901
End: 1090684
Strand: Direct
Name: uvrA [H]
Synonym: Teth514_1053
Alternate gene names: 167039703
Gene position: 1087901-1090684 (Clockwise)
Preceding gene: 167039702
Following gene: 167039704
Centisome position: 44.27
GC content: 36.89
Gene sequence:
>2784_bases ATGGCGAAAGACAAAATTGTAATTAAAGGGGCAAGAGTTCATAATTTAAAAAATGTAGATTTGGAGATTCCACGAGATAA ATTAACTGTGATAACGGGTTTATCAGGTTCTGGTAAGTCTTCTCTTGCCTTTGATACCATTTATGCTGAAGGTCAGAGAA GATATGTGGAGTCGTTGTCAGCTTATGCAAGGCAATTTTTAGGACAAATGGACAAACCAGACGTTGATTATATAGAAGGT CTTTCACCGGCAATATCTATAGACCAAAAGACCACAAATAAAAACCCTCGTTCTACGGTAGGAACGATAACTGAGATTTA CGACTATCTAAGACTTTTATATGCAAGGGCTGGGATTCCCCATTGTCCTGTTTGTGGAAAAGAGATTAGCATGCAAACTA TAGATCAGATGGTAGACAGAGTCAAAGAATTGCCAGAAGGTACAAGGATACAGGTACTGGCTCCTGTTATTAGAGGAAGA AAAGGGGAATATGCTAAGCTTTTAAATGACATAAAAAAGAGCGGATATGTCAGAGTGAAAATTGATGGAGTCATGTACGA TGTAAATGAGGAGATTAAACTTGACAAAAATAAAAAGCATACTATTGAAGTTGTGGTAGACAGGGTTATTATAAAACCGG GAATAGACATGAGGTTGACAGACTCTATAGAAACAGCTTTAAAATTAGCAGATGGGATAGTTTCTATTGATGTAATAGAC GGAGAAAGCTTTACACTCTCTGAAAAATACGCTTGTACAGAGTGCAACATAAGTATTGAAGAACTTTCCCCGAGAATGTT TTCCTTCAATAGCCCTTATGGGGTTTGCCCTGTTTGCACTGGATTGGGAGAATTTATGAAGGTAGATCCAGAGCTTTTAA TACAAGACCCTAAAAAATCATTAGCAAATGGGTTGTTGCCGGGGATTGTTGCTTCACAGGATAGTTATGCTTATTACAAC ATTTTAAGATTAATTGAACATTTTGGATATACAGAGAATACTCCTTATGAAAAGTTTAGTGAAGATTTAAAGAATGTACT GCTTTATGGCAAAGATACAAAAGGTAAGTCCTATGGATTTGAAGGTATAGTAAACAATCTTGAAAGAAGGTACAACAATA CTTCTTCAGATTTTATAAAAGAAGAGATAGAGAAATATATGAGACCGGTTACTTGTCCTGCATGCCATGGGGCTAGATTA AAGCCAGAAGCGCTAGCTGTGACTGTTGGTGGACTTTCCATAAAAGAAATGACAGACCTTTCTGTTGGCGAGCTTATAAA ATTTATTGAGGAACTCAAATTAACAGAAAAACAAGAGATTATTGCAAAGCCAATTTTAAAAGAAATAAAGGCAAGGCTTA ATTTTCTTGTGGATGTAGGACTGGATTATTTGACTCTTTCAAGACCTGCAGCTACTTTATCAGGTGGAGAAGCACAAAGG ATAAGATTGGCAAGCCAGATAGGCTCTGGGCTTGTAGGAGTCACATACATCCTGGACGAGCCGAGCATTGGACTTCATCA AAGAGATAATGAAAGGCTTATAAATTCCTTGAAAAAATTAAGAGACCAAGGCAATACTCTTATAGTAGTAGAGCACGATG AGGATACAATATATGCGGCAGACTACATTGTGGATGTAGGACCAGGCGCAGGTGAGCATGGAGGAGAAATTGTAATTGCG GGTACGATAGAAGATGTGTTAAAATGTGAAAAATCAATTACAGGCCAGTATTTAAGTGGTAAAATAAAGATAGAAGTGCC AAAACAGAGGAGAAAACCTAATGGAAAAGCTTTAATAGTGAAAGGAGCTAAGGAAAACAATTTAAAGAATATAGATGTGG TTTTCCCCCTCGGAGTATTTATATGTGTTACAGGGGTTTCTGGCTCAGGCAAAAGCACCCTTATAAATGAGATACTGTAC AAAGCATTGGCACAGAAGATTTATAAGTCCAAAGATAAACCAGGTATGCACGATGCAATAGAGGGTATCGATAATATAGA TAAAGTAATAAATATTGACCAGTCTCCTATAGGCAGGACTCCTCGCTCAAATCCTGCTACCTATACAGGAGTTTTCGACT ATATAAGAGAGGTTTTTGCAAATACTCCAGAAGCTAAAATGAGAGGCTATAAACCAGGAAGATTTAGTTTTAATGTTAAA GGTGGAAGGTGTGAAGCCTGTGGTGGAGATGGTATAATTAAAATTGAGATGAACTTTTTGCCGGATGTGTATGTCCCTTG TGAAGTCTGCAAAGGGCAAAGGTATAATAGGGAAACATTGGAAGTAAAATATAAAGGGAAAAATATTTCGGATGTACTTA ATATGACGGTAGAAGAGGCGTTAGAATTTTTTGAAAATATACCCAGGATAAAAAATAAATTGATGACTTTATATGATGTG GGTTTAGGATATATTAAGCTAGGGCAACCTTCTACTCAGCTTTCAGGAGGAGAAGCACAAAGAGTAAAATTAGCTACTGA ACTTTCTAAAAGGCCTACAGGTAAAACACTATATATTTTGGATGAGCCTACAACTGGATTACATTTTGCAGATGTGCATA GGCTTCTTGAAGTTTTAAATAGATTAACTGATGCGGGCAATACTGTTATTGTAATTGAACACAACTTAGATATCATAAAA AGTGCAGACTATATCATTGACTTAGGACCAGAAGGTGGAGACAAGGGTGGAAGGGTAATAGCTACAGGGACACCTGAAGA AGTTGCTGCTAATGAGAATTCTTATACAGGCCATTTTTTGAAAAAAGTCCTTTCTCAAAAATGA
Upstream 100 bases:
>100_bases AGAAGCTGCAATTGAGCTGCAGTTTGAAAAGGCTGCAAAATTGAGAGATGTGATTTTTGAATTGAAGAAACAGTTGGAGG AAGTAGTTTGAGGTGAAATC
Downstream 100 bases:
>100_bases GGTGAATTTATGTATTATGCCATAGCTTCTCAGATATTAAAATATGTCCTTATTTTTCTCATCTACCTGTTTTTATACAG GGTTTTTAAAATAGTGTATA
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 927; Mature: 926
Protein sequence:
>927_residues MAKDKIVIKGARVHNLKNVDLEIPRDKLTVITGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDYIEG LSPAISIDQKTTNKNPRSTVGTITEIYDYLRLLYARAGIPHCPVCGKEISMQTIDQMVDRVKELPEGTRIQVLAPVIRGR KGEYAKLLNDIKKSGYVRVKIDGVMYDVNEEIKLDKNKKHTIEVVVDRVIIKPGIDMRLTDSIETALKLADGIVSIDVID GESFTLSEKYACTECNISIEELSPRMFSFNSPYGVCPVCTGLGEFMKVDPELLIQDPKKSLANGLLPGIVASQDSYAYYN ILRLIEHFGYTENTPYEKFSEDLKNVLLYGKDTKGKSYGFEGIVNNLERRYNNTSSDFIKEEIEKYMRPVTCPACHGARL KPEALAVTVGGLSIKEMTDLSVGELIKFIEELKLTEKQEIIAKPILKEIKARLNFLVDVGLDYLTLSRPAATLSGGEAQR IRLASQIGSGLVGVTYILDEPSIGLHQRDNERLINSLKKLRDQGNTLIVVEHDEDTIYAADYIVDVGPGAGEHGGEIVIA GTIEDVLKCEKSITGQYLSGKIKIEVPKQRRKPNGKALIVKGAKENNLKNIDVVFPLGVFICVTGVSGSGKSTLINEILY KALAQKIYKSKDKPGMHDAIEGIDNIDKVINIDQSPIGRTPRSNPATYTGVFDYIREVFANTPEAKMRGYKPGRFSFNVK GGRCEACGGDGIIKIEMNFLPDVYVPCEVCKGQRYNRETLEVKYKGKNISDVLNMTVEEALEFFENIPRIKNKLMTLYDV GLGYIKLGQPSTQLSGGEAQRVKLATELSKRPTGKTLYILDEPTTGLHFADVHRLLEVLNRLTDAGNTVIVIEHNLDIIK SADYIIDLGPEGGDKGGRVIATGTPEEVAANENSYTGHFLKKVLSQK
Sequences:
>Translated_927_residues MAKDKIVIKGARVHNLKNVDLEIPRDKLTVITGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDYIEG LSPAISIDQKTTNKNPRSTVGTITEIYDYLRLLYARAGIPHCPVCGKEISMQTIDQMVDRVKELPEGTRIQVLAPVIRGR KGEYAKLLNDIKKSGYVRVKIDGVMYDVNEEIKLDKNKKHTIEVVVDRVIIKPGIDMRLTDSIETALKLADGIVSIDVID GESFTLSEKYACTECNISIEELSPRMFSFNSPYGVCPVCTGLGEFMKVDPELLIQDPKKSLANGLLPGIVASQDSYAYYN ILRLIEHFGYTENTPYEKFSEDLKNVLLYGKDTKGKSYGFEGIVNNLERRYNNTSSDFIKEEIEKYMRPVTCPACHGARL KPEALAVTVGGLSIKEMTDLSVGELIKFIEELKLTEKQEIIAKPILKEIKARLNFLVDVGLDYLTLSRPAATLSGGEAQR IRLASQIGSGLVGVTYILDEPSIGLHQRDNERLINSLKKLRDQGNTLIVVEHDEDTIYAADYIVDVGPGAGEHGGEIVIA GTIEDVLKCEKSITGQYLSGKIKIEVPKQRRKPNGKALIVKGAKENNLKNIDVVFPLGVFICVTGVSGSGKSTLINEILY KALAQKIYKSKDKPGMHDAIEGIDNIDKVINIDQSPIGRTPRSNPATYTGVFDYIREVFANTPEAKMRGYKPGRFSFNVK GGRCEACGGDGIIKIEMNFLPDVYVPCEVCKGQRYNRETLEVKYKGKNISDVLNMTVEEALEFFENIPRIKNKLMTLYDV GLGYIKLGQPSTQLSGGEAQRVKLATELSKRPTGKTLYILDEPTTGLHFADVHRLLEVLNRLTDAGNTVIVIEHNLDIIK SADYIIDLGPEGGDKGGRVIATGTPEEVAANENSYTGHFLKKVLSQK >Mature_926_residues AKDKIVIKGARVHNLKNVDLEIPRDKLTVITGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDYIEGL SPAISIDQKTTNKNPRSTVGTITEIYDYLRLLYARAGIPHCPVCGKEISMQTIDQMVDRVKELPEGTRIQVLAPVIRGRK GEYAKLLNDIKKSGYVRVKIDGVMYDVNEEIKLDKNKKHTIEVVVDRVIIKPGIDMRLTDSIETALKLADGIVSIDVIDG ESFTLSEKYACTECNISIEELSPRMFSFNSPYGVCPVCTGLGEFMKVDPELLIQDPKKSLANGLLPGIVASQDSYAYYNI LRLIEHFGYTENTPYEKFSEDLKNVLLYGKDTKGKSYGFEGIVNNLERRYNNTSSDFIKEEIEKYMRPVTCPACHGARLK PEALAVTVGGLSIKEMTDLSVGELIKFIEELKLTEKQEIIAKPILKEIKARLNFLVDVGLDYLTLSRPAATLSGGEAQRI RLASQIGSGLVGVTYILDEPSIGLHQRDNERLINSLKKLRDQGNTLIVVEHDEDTIYAADYIVDVGPGAGEHGGEIVIAG TIEDVLKCEKSITGQYLSGKIKIEVPKQRRKPNGKALIVKGAKENNLKNIDVVFPLGVFICVTGVSGSGKSTLINEILYK ALAQKIYKSKDKPGMHDAIEGIDNIDKVINIDQSPIGRTPRSNPATYTGVFDYIREVFANTPEAKMRGYKPGRFSFNVKG GRCEACGGDGIIKIEMNFLPDVYVPCEVCKGQRYNRETLEVKYKGKNISDVLNMTVEEALEFFENIPRIKNKLMTLYDVG LGYIKLGQPSTQLSGGEAQRVKLATELSKRPTGKTLYILDEPTTGLHFADVHRLLEVLNRLTDAGNTVIVIEHNLDIIKS ADYIIDLGPEGGDKGGRVIATGTPEEVAANENSYTGHFLKKVLSQK
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=941, Percent_Identity=57.7045696068013, Blast_Score=1094, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR003593 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 102604; Mature: 102473
Theoretical pI: Translated: 6.97; Mature: 6.97
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAKDKIVIKGARVHNLKNVDLEIPRDKLTVITGLSGSGKSSLAFDTIYAEGQRRYVESLS CCCCCEEEECCEECCCCCCCEECCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHH AYARQFLGQMDKPDVDYIEGLSPAISIDQKTTNKNPRSTVGTITEIYDYLRLLYARAGIP HHHHHHHCCCCCCCHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC HCPVCGKEISMQTIDQMVDRVKELPEGTRIQVLAPVIRGRKGEYAKLLNDIKKSGYVRVK CCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCHHHHHHHHHHCCEEEEE IDGVMYDVNEEIKLDKNKKHTIEVVVDRVIIKPGIDMRLTDSIETALKLADGIVSIDVID ECCEEEECCCCEEECCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHCCEEEEEEEC GESFTLSEKYACTECNISIEELSPRMFSFNSPYGVCPVCTGLGEFMKVDPELLIQDPKKS CCCEEECCCCEEEECCEEHHHCCCCCEECCCCCCCCHHHHCCHHHHHCCHHHEECCCHHH LANGLLPGIVASQDSYAYYNILRLIEHFGYTENTPYEKFSEDLKNVLLYGKDTKGKSYGF HHCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCCH EGIVNNLERRYNNTSSDFIKEEIEKYMRPVTCPACHGARLKPEALAVTVGGLSIKEMTDL HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHCC SVGELIKFIEELKLTEKQEIIAKPILKEIKARLNFLVDVGLDYLTLSRPAATLSGGEAQR CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHH IRLASQIGSGLVGVTYILDEPSIGLHQRDNERLINSLKKLRDQGNTLIVVEHDEDTIYAA HHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEE DYIVDVGPGAGEHGGEIVIAGTIEDVLKCEKSITGQYLSGKIKIEVPKQRRKPNGKALIV EEEEECCCCCCCCCCEEEEEECHHHHHHHHHHHCCCEECCEEEEECCHHHCCCCCCEEEE KGAKENNLKNIDVVFPLGVFICVTGVSGSGKSTLINEILYKALAQKIYKSKDKPGMHDAI ECCCCCCCCEEEEEECCCEEHEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH EGIDNIDKVINIDQSPIGRTPRSNPATYTGVFDYIREVFANTPEAKMRGYKPGRFSFNVK HHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEC GGRCEACGGDGIIKIEMNFLPDVYVPCEVCKGQRYNRETLEVKYKGKNISDVLNMTVEEA CCEEEECCCCCEEEEEECCCCCCCCCHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHH LEFFENIPRIKNKLMTLYDVGLGYIKLGQPSTQLSGGEAQRVKLATELSKRPTGKTLYIL HHHHHHCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEE DEPTTGLHFADVHRLLEVLNRLTDAGNTVIVIEHNLDIIKSADYIIDLGPEGGDKGGRVI ECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCEEEEECCCCCCCCCEEE ATGTPEEVAANENSYTGHFLKKVLSQK ECCCCHHHHCCCCCCCHHHHHHHHCCC >Mature Secondary Structure AKDKIVIKGARVHNLKNVDLEIPRDKLTVITGLSGSGKSSLAFDTIYAEGQRRYVESLS CCCCEEEECCEECCCCCCCEECCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHH AYARQFLGQMDKPDVDYIEGLSPAISIDQKTTNKNPRSTVGTITEIYDYLRLLYARAGIP HHHHHHHCCCCCCCHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC HCPVCGKEISMQTIDQMVDRVKELPEGTRIQVLAPVIRGRKGEYAKLLNDIKKSGYVRVK CCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCHHHHHHHHHHCCEEEEE IDGVMYDVNEEIKLDKNKKHTIEVVVDRVIIKPGIDMRLTDSIETALKLADGIVSIDVID ECCEEEECCCCEEECCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHCCEEEEEEEC GESFTLSEKYACTECNISIEELSPRMFSFNSPYGVCPVCTGLGEFMKVDPELLIQDPKKS CCCEEECCCCEEEECCEEHHHCCCCCEECCCCCCCCHHHHCCHHHHHCCHHHEECCCHHH LANGLLPGIVASQDSYAYYNILRLIEHFGYTENTPYEKFSEDLKNVLLYGKDTKGKSYGF HHCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCCH EGIVNNLERRYNNTSSDFIKEEIEKYMRPVTCPACHGARLKPEALAVTVGGLSIKEMTDL HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHCC SVGELIKFIEELKLTEKQEIIAKPILKEIKARLNFLVDVGLDYLTLSRPAATLSGGEAQR CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHH IRLASQIGSGLVGVTYILDEPSIGLHQRDNERLINSLKKLRDQGNTLIVVEHDEDTIYAA HHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEE DYIVDVGPGAGEHGGEIVIAGTIEDVLKCEKSITGQYLSGKIKIEVPKQRRKPNGKALIV EEEEECCCCCCCCCCEEEEEECHHHHHHHHHHHCCCEECCEEEEECCHHHCCCCCCEEEE KGAKENNLKNIDVVFPLGVFICVTGVSGSGKSTLINEILYKALAQKIYKSKDKPGMHDAI ECCCCCCCCEEEEEECCCEEHEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH EGIDNIDKVINIDQSPIGRTPRSNPATYTGVFDYIREVFANTPEAKMRGYKPGRFSFNVK HHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEC GGRCEACGGDGIIKIEMNFLPDVYVPCEVCKGQRYNRETLEVKYKGKNISDVLNMTVEEA CCEEEECCCCCEEEEEECCCCCCCCCHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHH LEFFENIPRIKNKLMTLYDVGLGYIKLGQPSTQLSGGEAQRVKLATELSKRPTGKTLYIL HHHHHHCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEE DEPTTGLHFADVHRLLEVLNRLTDAGNTVIVIEHNLDIIKSADYIIDLGPEGGDKGGRVI ECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCEEEEECCCCCCCCCEEE ATGTPEEVAANENSYTGHFLKKVLSQK ECCCCHHHHCCCCCCCHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12552129 [H]