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The map label for this gene is uvrB [H]

Identifier: 167039702

GI number: 167039702

Start: 1085906

End: 1087891

Strand: Direct

Name: uvrB [H]

Synonym: Teth514_1052

Alternate gene names: 167039702

Gene position: 1085906-1087891 (Clockwise)

Preceding gene: 167039701

Following gene: 167039703

Centisome position: 44.19

GC content: 36.4

Gene sequence:

>1986_bases
ATGAGTGGATTTAAGTTGGTATCTAATTTTAAACCAACAGGAGACCAACCTCAAGCTATAGATAAATTAGTTGAAGGGGT
AAAAAAAGGATATAGATTTCAAACCTTATTGGGTGTGACGGGTTCTGGAAAAACCTTTACTATGGCTAATATAATCCAGA
AGTTAAATCGTCCTACTCTTGTCATCGCTCATAACAAGACCTTGGCTGCACAATTGTACAGCGAATTTAAAGAGTTTTTT
CCAGACAATGCGGTAGAATATTTTGTGAGTTATTATGACTACTACCAACCGGAGGCTTATATACCCCAAACTGATACTTA
TATTGAAAAAGATGCTTCTATAAATGAAGAAATAGATAAATTGAGGCACTCTGCTACGGCAGCTCTTTTTGAGCGAAGAG
ACGTTATAATTGTCGCCAGTGTTTCTTGTATATATGGCTTAGGTGACCCTGTAGATTACGAAAATCTTATGCTTTCTCTA
AGGCCGGGAATGATAAAAGATAGGGACGAAATAATTAAAAAGCTTGTAGATATACAATATGAAAGAAATGATGTGAATTT
TACAAGAGGCAAATTCAGGGTAAGAGGAGATGTTATAGAAATTTTCCCTGCTTCTTTTTCCAATAAGGCGATAAGGGTTG
AGCTTTTTGGAGATGAAATTGACAGAATAGCGGAAATTGATGTGTTAACAGGTGAAGTACTGGGATTAAGAAAACACGTG
GCTATATTTCCGGCTTCTCACTATGCTACTTCAAAAGACAAATTGGAAAGAGCGATAAAAAGCATTCGAGAAGAACTGGA
GCAAAGGTACAAAGAGCTTAAAGATGCTGGCAAAATAGTAGAGGCTGAAAGACTAAGACAGAGGACAAATTACGACTTAG
AGATGCTTCAAGAGATGGGCTACTGCCAAGGAATAGAAAATTATTCAAGGCATATTTCAGGAAGACCTCCAGGAAGCCCT
CCTTATACTCTTTTAGATTATTTCCCTAAAGATTTCCTTATCTTTATAGATGAGTCTCATGTGACAATTCCTCAGATTAG
AGGGATGTACAATGGAGATAGGTCGAGAAAAGAAGCATTAGTAGAATACGGATTTAGACTTCCTTCTGCCTTTGACAATC
GTCCTCTTACTTTTGAAGAGTTTGAAAAGAGGATAAATCAAGTTATCTTTGTTTCTGCAACACCAGGACCTTACGAGCTT
GAACATTCGGAGCAAGTTGTTGAGCAGTTAATACGACCGACAGGTCTTATAGATCCAGAAGTGATTGTAAAACCTGTAAA
AGGGCAAGTAGATGACTTAATAGGAGAAATTAGAAAGACGGTAGACAAAGGCTTTAGAGTACTTGTTACAACTCTTACGA
AAAAAATGGCAGAGGATTTAACGGATTATCTAAAAGATATGGGAATAAAAGTAAAATATTTACATTCTGATATTGAGACG
ATTGAAAGGGTGGAAATAATAAGAGATTTAAGGCTGGGTAAATTCGATGTTTTAATAGGCATAAATCTTTTAAGAGAAGG
GTTGGATATACCTGAGGTTGCTTTGGTGGCAATATTAGACGCAGACAAAGAGGGATTTTTGCGTTCAGAGACTTCCTTAA
TACAGACTATAGGACGTGCCGCAAGAAATGCGGAAGGACGAGTAATAATGTATGCAGATACTGTAACAAATTCTATGAAG
AGAGCAATTGATGAGACGAATAGAAGAAGAAAGATACAAATGGAATATAACAAAAAGCATGGTATAACTCCAAAGACAGT
AATTAAGGGAGTAAGAGATGTAATTGAAGCTACTCACGTAGCTGAAGAAGAACAGAAGTACAGAAGAAAGAAAGTTAAGA
CTTATGACCCTGAAATTATTAAGTCAACTATAGAGCAACTTGAAAAAGAAATGAAAGAAGCTGCAATTGAGCTGCAGTTT
GAAAAGGCTGCAAAATTGAGAGATGTGATTTTTGAATTGAAGAAACAGTTGGAGGAAGTAGTTTGA

Upstream 100 bases:

>100_bases
CCTACAAGATCTTGACACGGACGGCTGTTTGGTTATGTTTGTGTTGACAAGTAGGGTATGCTATAATAATAAGATGATAA
TTGCAAAGAGGGTAGAAAAA

Downstream 100 bases:

>100_bases
GGTGAAATCATGGCGAAAGACAAAATTGTAATTAAAGGGGCAAGAGTTCATAATTTAAAAAATGTAGATTTGGAGATTCC
ACGAGATAAATTAACTGTGA

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MSGFKLVSNFKPTGDQPQAIDKLVEGVKKGYRFQTLLGVTGSGKTFTMANIIQKLNRPTLVIAHNKTLAAQLYSEFKEFF
PDNAVEYFVSYYDYYQPEAYIPQTDTYIEKDASINEEIDKLRHSATAALFERRDVIIVASVSCIYGLGDPVDYENLMLSL
RPGMIKDRDEIIKKLVDIQYERNDVNFTRGKFRVRGDVIEIFPASFSNKAIRVELFGDEIDRIAEIDVLTGEVLGLRKHV
AIFPASHYATSKDKLERAIKSIREELEQRYKELKDAGKIVEAERLRQRTNYDLEMLQEMGYCQGIENYSRHISGRPPGSP
PYTLLDYFPKDFLIFIDESHVTIPQIRGMYNGDRSRKEALVEYGFRLPSAFDNRPLTFEEFEKRINQVIFVSATPGPYEL
EHSEQVVEQLIRPTGLIDPEVIVKPVKGQVDDLIGEIRKTVDKGFRVLVTTLTKKMAEDLTDYLKDMGIKVKYLHSDIET
IERVEIIRDLRLGKFDVLIGINLLREGLDIPEVALVAILDADKEGFLRSETSLIQTIGRAARNAEGRVIMYADTVTNSMK
RAIDETNRRRKIQMEYNKKHGITPKTVIKGVRDVIEATHVAEEEQKYRRKKVKTYDPEIIKSTIEQLEKEMKEAAIELQF
EKAAKLRDVIFELKKQLEEVV

Sequences:

>Translated_661_residues
MSGFKLVSNFKPTGDQPQAIDKLVEGVKKGYRFQTLLGVTGSGKTFTMANIIQKLNRPTLVIAHNKTLAAQLYSEFKEFF
PDNAVEYFVSYYDYYQPEAYIPQTDTYIEKDASINEEIDKLRHSATAALFERRDVIIVASVSCIYGLGDPVDYENLMLSL
RPGMIKDRDEIIKKLVDIQYERNDVNFTRGKFRVRGDVIEIFPASFSNKAIRVELFGDEIDRIAEIDVLTGEVLGLRKHV
AIFPASHYATSKDKLERAIKSIREELEQRYKELKDAGKIVEAERLRQRTNYDLEMLQEMGYCQGIENYSRHISGRPPGSP
PYTLLDYFPKDFLIFIDESHVTIPQIRGMYNGDRSRKEALVEYGFRLPSAFDNRPLTFEEFEKRINQVIFVSATPGPYEL
EHSEQVVEQLIRPTGLIDPEVIVKPVKGQVDDLIGEIRKTVDKGFRVLVTTLTKKMAEDLTDYLKDMGIKVKYLHSDIET
IERVEIIRDLRLGKFDVLIGINLLREGLDIPEVALVAILDADKEGFLRSETSLIQTIGRAARNAEGRVIMYADTVTNSMK
RAIDETNRRRKIQMEYNKKHGITPKTVIKGVRDVIEATHVAEEEQKYRRKKVKTYDPEIIKSTIEQLEKEMKEAAIELQF
EKAAKLRDVIFELKKQLEEVV
>Mature_660_residues
SGFKLVSNFKPTGDQPQAIDKLVEGVKKGYRFQTLLGVTGSGKTFTMANIIQKLNRPTLVIAHNKTLAAQLYSEFKEFFP
DNAVEYFVSYYDYYQPEAYIPQTDTYIEKDASINEEIDKLRHSATAALFERRDVIIVASVSCIYGLGDPVDYENLMLSLR
PGMIKDRDEIIKKLVDIQYERNDVNFTRGKFRVRGDVIEIFPASFSNKAIRVELFGDEIDRIAEIDVLTGEVLGLRKHVA
IFPASHYATSKDKLERAIKSIREELEQRYKELKDAGKIVEAERLRQRTNYDLEMLQEMGYCQGIENYSRHISGRPPGSPP
YTLLDYFPKDFLIFIDESHVTIPQIRGMYNGDRSRKEALVEYGFRLPSAFDNRPLTFEEFEKRINQVIFVSATPGPYELE
HSEQVVEQLIRPTGLIDPEVIVKPVKGQVDDLIGEIRKTVDKGFRVLVTTLTKKMAEDLTDYLKDMGIKVKYLHSDIETI
ERVEIIRDLRLGKFDVLIGINLLREGLDIPEVALVAILDADKEGFLRSETSLIQTIGRAARNAEGRVIMYADTVTNSMKR
AIDETNRRRKIQMEYNKKHGITPKTVIKGVRDVIEATHVAEEEQKYRRKKVKTYDPEIIKSTIEQLEKEMKEAAIELQFE
KAAKLRDVIFELKKQLEEVV

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=663, Percent_Identity=59.7285067873303, Blast_Score=785, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 75967; Mature: 75836

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGFKLVSNFKPTGDQPQAIDKLVEGVKKGYRFQTLLGVTGSGKTFTMANIIQKLNRPTL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHHHHCCCCEE
VIAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYIPQTDTYIEKDASINEEIDK
EEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCHHHHHH
LRHSATAALFERRDVIIVASVSCIYGLGDPVDYENLMLSLRPGMIKDRDEIIKKLVDIQY
HHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCEE
ERNDVNFTRGKFRVRGDVIEIFPASFSNKAIRVELFGDEIDRIAEIDVLTGEVLGLRKHV
CCCCCCEECCEEEEECCEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
AIFPASHYATSKDKLERAIKSIREELEQRYKELKDAGKIVEAERLRQRTNYDLEMLQEMG
EEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YCQGIENYSRHISGRPPGSPPYTLLDYFPKDFLIFIDESHVTIPQIRGMYNGDRSRKEAL
HHCCHHHHHHHCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHH
VEYGFRLPSAFDNRPLTFEEFEKRINQVIFVSATPGPYELEHSEQVVEQLIRPTGLIDPE
HHHHCCCCCCCCCCCCCHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCHH
VIVKPVKGQVDDLIGEIRKTVDKGFRVLVTTLTKKMAEDLTDYLKDMGIKVKYLHSDIET
HHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHH
IERVEIIRDLRLGKFDVLIGINLLREGLDIPEVALVAILDADKEGFLRSETSLIQTIGRA
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHEECCCCCCCHHHHHHHHHHHHHH
ARNAEGRVIMYADTVTNSMKRAIDETNRRRKIQMEYNKKHGITPKTVIKGVRDVIEATHV
HCCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
AEEEQKYRRKKVKTYDPEIIKSTIEQLEKEMKEAAIELQFEKAAKLRDVIFELKKQLEEV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
V
C
>Mature Secondary Structure 
SGFKLVSNFKPTGDQPQAIDKLVEGVKKGYRFQTLLGVTGSGKTFTMANIIQKLNRPTL
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHHHHCCCCEE
VIAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYIPQTDTYIEKDASINEEIDK
EEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCHHHHHH
LRHSATAALFERRDVIIVASVSCIYGLGDPVDYENLMLSLRPGMIKDRDEIIKKLVDIQY
HHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCEE
ERNDVNFTRGKFRVRGDVIEIFPASFSNKAIRVELFGDEIDRIAEIDVLTGEVLGLRKHV
CCCCCCEECCEEEEECCEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
AIFPASHYATSKDKLERAIKSIREELEQRYKELKDAGKIVEAERLRQRTNYDLEMLQEMG
EEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YCQGIENYSRHISGRPPGSPPYTLLDYFPKDFLIFIDESHVTIPQIRGMYNGDRSRKEAL
HHCCHHHHHHHCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHH
VEYGFRLPSAFDNRPLTFEEFEKRINQVIFVSATPGPYELEHSEQVVEQLIRPTGLIDPE
HHHHCCCCCCCCCCCCCHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCHH
VIVKPVKGQVDDLIGEIRKTVDKGFRVLVTTLTKKMAEDLTDYLKDMGIKVKYLHSDIET
HHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHH
IERVEIIRDLRLGKFDVLIGINLLREGLDIPEVALVAILDADKEGFLRSETSLIQTIGRA
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHEECCCCCCCHHHHHHHHHHHHHH
ARNAEGRVIMYADTVTNSMKRAIDETNRRRKIQMEYNKKHGITPKTVIKGVRDVIEATHV
HCCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
AEEEQKYRRKKVKTYDPEIIKSTIEQLEKEMKEAAIELQFEKAAKLRDVIFELKKQLEEV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]