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The map label for this gene is nuoN [H]

Identifier: 167039569

GI number: 167039569

Start: 939367

End: 940827

Strand: Direct

Name: nuoN [H]

Synonym: Teth514_0917

Alternate gene names: 167039569

Gene position: 939367-940827 (Clockwise)

Preceding gene: 167039568

Following gene: 167039570

Centisome position: 38.23

GC content: 35.46

Gene sequence:

>1461_bases
ATGAATCACATTCCAATTGTATTAATAATATCCCTTTTCAGCCATGCTTTTTTAACTCCTCTGTTAAAGAAAAAATTTCG
CAGCCTATACATATTCAGTCTTGCTTTATATTCTTTGTTGCTTTTTCTAACAGGTAAAACATTTTTTTACGTCGAATCGA
TGGGGCCTATTAGGTACTGGATAGGAGGATGGATCCCTCCGATAGGTATAGAACTTTATGCGGATAAACTTTCGGTCTTT
ATGGCTACTCTTTTTTTGAGCTGCGCCTTATTAATTCTTGTTAGCTTTGAGTCGTTTAAGTACGAGATAGGAGAAGAAAA
GGCAGCATATTATTTTATGCTAGTTTCAATTTTAATTGGCGCTATGCTGGGCATAATCTTTACCAGGGACCTCTTTAATT
TATATGTTTTTGTAGAAATTACAACAATTGCTGCTTGTGGAATTATATCTATAAAAAATGAAAAGAAAGCGGTGGAAGCT
GCTCTTAAATATTTTATATTGAGCTCTATAGCATCTACCTCTATATTACTTGGCCTGATCCTCATATACAATATAGGTGG
TTATTTACACTACGATACATTAAAATCTGTTTTGCTAGAATCTAAGGATGTATTTCCGAAGATTATATCTGGATCTTTAG
TACTTATAATATCAGGATTTAGCTTGAAATCTGCTCTCTTTCCTTTGCACATATGGCTCCCCGATGCCCACTCTGCCGCC
CCTACAACATCAAGCGCTCTATTGTCCGGATTAGTTATAAAAGTTTATGTTTTCGCCATAATACGCCTGCTAAACGATGT
TTTTGGTCTAATGTATACATACACTTCAATTTTGTTGGAGGTCCTTTTAGCATTAGGCAATGTTGGTGTATTTTCTGGGG
CTGTTTTGGCGGGATTTCAAAACGATATAAAAAGAAGGTTAGCTTATTCAAGTGTATCTCAAATGGGCTATGTTTTTTTA
GGTCTCGGCTTTAATAATCAGTACGGATTTGAAGGAGCATTGTTACAGGTATTAAACCATGCCCTTGCCAAAAGCGGTTT
GTTTTTAGCTGCAGGCTGGATGGTCAAATTCACTGGCACAAGAGATATAAAAGGACTAGAAAAAATCAGTGACAAATTGC
CGCTGACAGCTCTTTGCTTTTCTGTATGTGCCATGTCTTTGGTGGGGATGCCTTTTACCTTGGGATTTTTATCAAAGTGG
CACTTGGCTATGGCCGCTATAGAATCGGGAAGGCCTTTACAATTAATTTTTATAATATTATCTGCCCTTTTGACATTAAG
TTATTATTTTCCCATCATAGTAAAGGCCTTTACAGGCGATAAATCCTTTGAAAGAAAGTTAGAATTTGAAAAGATAAAGG
GCGGTAGTTTGATTTCCATTCTTATATTTACTTTTGTTATCATGTTTTTAGGCATTTATCCTAAATTTTTGTTAAAATAT
TTGTTGCAGAACATGTTCTAA

Upstream 100 bases:

>100_bases
TTAGTAAGACTGCATATGCTCTTACGCTCATTACTAAGATTCACGATTTTTACGGTTCTATAGATATTGATAATATTTAT
AAGTCCGGGTGAAAATGGTT

Downstream 100 bases:

>100_bases
GGAGAGTGAAAGCAATGAGCTCATTGAGCTTACTTTTTATATTGGTACTCCCAATTATAGGTACGCTGGTAATATGGCCT
GCCAGTAAAAAAAATGATAA

Product: NADH dehydrogenase (quinone)

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MNHIPIVLIISLFSHAFLTPLLKKKFRSLYIFSLALYSLLLFLTGKTFFYVESMGPIRYWIGGWIPPIGIELYADKLSVF
MATLFLSCALLILVSFESFKYEIGEEKAAYYFMLVSILIGAMLGIIFTRDLFNLYVFVEITTIAACGIISIKNEKKAVEA
ALKYFILSSIASTSILLGLILIYNIGGYLHYDTLKSVLLESKDVFPKIISGSLVLIISGFSLKSALFPLHIWLPDAHSAA
PTTSSALLSGLVIKVYVFAIIRLLNDVFGLMYTYTSILLEVLLALGNVGVFSGAVLAGFQNDIKRRLAYSSVSQMGYVFL
GLGFNNQYGFEGALLQVLNHALAKSGLFLAAGWMVKFTGTRDIKGLEKISDKLPLTALCFSVCAMSLVGMPFTLGFLSKW
HLAMAAIESGRPLQLIFIILSALLTLSYYFPIIVKAFTGDKSFERKLEFEKIKGGSLISILIFTFVIMFLGIYPKFLLKY
LLQNMF

Sequences:

>Translated_486_residues
MNHIPIVLIISLFSHAFLTPLLKKKFRSLYIFSLALYSLLLFLTGKTFFYVESMGPIRYWIGGWIPPIGIELYADKLSVF
MATLFLSCALLILVSFESFKYEIGEEKAAYYFMLVSILIGAMLGIIFTRDLFNLYVFVEITTIAACGIISIKNEKKAVEA
ALKYFILSSIASTSILLGLILIYNIGGYLHYDTLKSVLLESKDVFPKIISGSLVLIISGFSLKSALFPLHIWLPDAHSAA
PTTSSALLSGLVIKVYVFAIIRLLNDVFGLMYTYTSILLEVLLALGNVGVFSGAVLAGFQNDIKRRLAYSSVSQMGYVFL
GLGFNNQYGFEGALLQVLNHALAKSGLFLAAGWMVKFTGTRDIKGLEKISDKLPLTALCFSVCAMSLVGMPFTLGFLSKW
HLAMAAIESGRPLQLIFIILSALLTLSYYFPIIVKAFTGDKSFERKLEFEKIKGGSLISILIFTFVIMFLGIYPKFLLKY
LLQNMF
>Mature_486_residues
MNHIPIVLIISLFSHAFLTPLLKKKFRSLYIFSLALYSLLLFLTGKTFFYVESMGPIRYWIGGWIPPIGIELYADKLSVF
MATLFLSCALLILVSFESFKYEIGEEKAAYYFMLVSILIGAMLGIIFTRDLFNLYVFVEITTIAACGIISIKNEKKAVEA
ALKYFILSSIASTSILLGLILIYNIGGYLHYDTLKSVLLESKDVFPKIISGSLVLIISGFSLKSALFPLHIWLPDAHSAA
PTTSSALLSGLVIKVYVFAIIRLLNDVFGLMYTYTSILLEVLLALGNVGVFSGAVLAGFQNDIKRRLAYSSVSQMGYVFL
GLGFNNQYGFEGALLQVLNHALAKSGLFLAAGWMVKFTGTRDIKGLEKISDKLPLTALCFSVCAMSLVGMPFTLGFLSKW
HLAMAAIESGRPLQLIFIILSALLTLSYYFPIIVKAFTGDKSFERKLEFEKIKGGSLISILIFTFVIMFLGIYPKFLLKY
LLQNMF

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0651

COG function: function code CP; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=374, Percent_Identity=27.0053475935829, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI251831116, Length=314, Percent_Identity=25.796178343949, Blast_Score=83, Evalue=7e-16,
Organism=Escherichia coli, GI1788831, Length=350, Percent_Identity=30.8571428571429, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788827, Length=447, Percent_Identity=24.1610738255034, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1788613, Length=351, Percent_Identity=29.9145299145299, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI1788829, Length=344, Percent_Identity=28.7790697674419, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1788614, Length=396, Percent_Identity=28.7878787878788, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI145693160, Length=433, Percent_Identity=24.7113163972286, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI2367154, Length=297, Percent_Identity=28.956228956229, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750
- InterPro:   IPR003918 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 54015; Mature: 54015

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHIPIVLIISLFSHAFLTPLLKKKFRSLYIFSLALYSLLLFLTGKTFFYVESMGPIRYW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHH
IGGWIPPIGIELYADKLSVFMATLFLSCALLILVSFESFKYEIGEEKAAYYFMLVSILIG
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AMLGIIFTRDLFNLYVFVEITTIAACGIISIKNEKKAVEAALKYFILSSIASTSILLGLI
HHHHHHHHHHHHHHHHHEEHHHHHHHCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIYNIGGYLHYDTLKSVLLESKDVFPKIISGSLVLIISGFSLKSALFPLHIWLPDAHSAA
HHHHCCCEEEHHHHHHHHHHCCCCCHHHHCCCEEEEEECCCHHHHHCEEEEECCCCCCCC
PTTSSALLSGLVIKVYVFAIIRLLNDVFGLMYTYTSILLEVLLALGNVGVFSGAVLAGFQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
NDIKRRLAYSSVSQMGYVFLGLGFNNQYGFEGALLQVLNHALAKSGLFLAAGWMVKFTGT
HHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEECEEEEECCC
RDIKGLEKISDKLPLTALCFSVCAMSLVGMPFTLGFLSKWHLAMAAIESGRPLQLIFIIL
CCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SALLTLSYYFPIIVKAFTGDKSFERKLEFEKIKGGSLISILIFTFVIMFLGIYPKFLLKY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLQNMF
HHHHCC
>Mature Secondary Structure
MNHIPIVLIISLFSHAFLTPLLKKKFRSLYIFSLALYSLLLFLTGKTFFYVESMGPIRYW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHH
IGGWIPPIGIELYADKLSVFMATLFLSCALLILVSFESFKYEIGEEKAAYYFMLVSILIG
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AMLGIIFTRDLFNLYVFVEITTIAACGIISIKNEKKAVEAALKYFILSSIASTSILLGLI
HHHHHHHHHHHHHHHHHEEHHHHHHHCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIYNIGGYLHYDTLKSVLLESKDVFPKIISGSLVLIISGFSLKSALFPLHIWLPDAHSAA
HHHHCCCEEEHHHHHHHHHHCCCCCHHHHCCCEEEEEECCCHHHHHCEEEEECCCCCCCC
PTTSSALLSGLVIKVYVFAIIRLLNDVFGLMYTYTSILLEVLLALGNVGVFSGAVLAGFQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
NDIKRRLAYSSVSQMGYVFLGLGFNNQYGFEGALLQVLNHALAKSGLFLAAGWMVKFTGT
HHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEECEEEEECCC
RDIKGLEKISDKLPLTALCFSVCAMSLVGMPFTLGFLSKWHLAMAAIESGRPLQLIFIIL
CCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SALLTLSYYFPIIVKAFTGDKSFERKLEFEKIKGGSLISILIFTFVIMFLGIYPKFLLKY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLQNMF
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA