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The map label for this gene is manP [H]

Identifier: 167039479

GI number: 167039479

Start: 859527

End: 860573

Strand: Direct

Name: manP [H]

Synonym: Teth514_0825

Alternate gene names: 167039479

Gene position: 859527-860573 (Clockwise)

Preceding gene: 167039478

Following gene: 167039480

Centisome position: 34.98

GC content: 38.97

Gene sequence:

>1047_bases
ATGAAGGAAGAATTAAAAAGGATTAGAGAATATTTAATGACAGGCGTATCTTACATGATACCTATAGTTGTCATAGGTGG
TGTTTTAATAGCTTTTTCAATTGCATTAAGTGGTGTGCAGGCTGGTAAAGGTGCAGTTGTTACAAATCCAGTGTTAAAAA
GTATGATGGATATTGGTACAGCTTCTTTTTCAATGATGGTGCCAGTTCTTGCAGGATTTATAGCTTTTGGAATAGCTGAT
AGACCTGGACTTGCTCCTGGACTTGTTGGTGGAGTACTTGCAAACCAGTTGAAGGCAGGTTTTTTAGGTGGAATTATTGC
AGGTTTTATCGCAGGATATGTTGCAAGGTGGATAAAGAGTTGGAGAGTTCCTAAGAATTTAAGACCTATAATGCCAATTT
TTGTAATCCCGTTGTTATCAGCACTTATTGTAGGTTTTCTTATGATATATATACTCGGTAATCCTATAAGCAGTGCAATG
ACAGCTATGACAAATTGGTTAAAATCCATGAGTACAGGAAATGCTGTGATTTTAGCAATGATAATGGGTGCGATGATAGC
TTTTGATATGGGGGGGCCTGTAAACAAAGTTGCATTCTTATTTGCTGCAGCAATGATAGGAGAAGGCGTATATACAATTA
TGGGACCAGTAGCAGTAGCAATATGCATTCCCCCGCTTGGGATGGGTGTTGCTACATTGTTAGCACCCAACAAGTACACT
AAAGCAGAAAAGGAAGCAGGGTATGGTGCACTTGCAATGGGGATGATTGGTATCACAGAAGGTGCTATACCTTTTGCTGC
AGCCGATCCATTAAGAGTAATACCATCTATAATGGTAGGCTCATCTATAGGTGCTGCGATAGCAGCAATAGGGAAGGTTG
GAGACCATGCACCACATGGTGGACCTATTGTGTTACCAGTTGTAGATAATAAAATCATGTTTATAGTAGCTGTACTAATA
GGTATTGCGGTTACTGCATTAATGGTAAATGCATTAAAAAAACCTGTTATTGAAGAAGTTGAAGATGAAAGTGAAGTTGC
TGAGTAA

Upstream 100 bases:

>100_bases
AAAAAGCAGTAACTGTCGAGGAAATTTTAAATGCTTTAAGTGATATCCAAGTAAGTTAAAAATAAACAAAAATAAAATAG
ATAAGGAGGATAAAAATACG

Downstream 100 bases:

>100_bases
AACTAAAAATAGTTTCAAGATTATGTAAATAATTTACAAAATTTTATAGAAAGAGGGATGGAATATGAAAATAGTTGCAG
TTACAGCTTGTCCTACAGGT

Product: PTS system, fructose subfamily, IIC subunit

Products: NA

Alternate protein names: EIIBCA-Man; EII-Man; Mannose-specific phosphotransferase enzyme IIB component; PTS system mannose-specific EIIB component; Mannose permease IIC component; PTS system mannose-specific EIIC component; Mannose-specific phosphotransferase enzyme IIA component; PTS system mannose-specific EIIA component [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKEELKRIREYLMTGVSYMIPIVVIGGVLIAFSIALSGVQAGKGAVVTNPVLKSMMDIGTASFSMMVPVLAGFIAFGIAD
RPGLAPGLVGGVLANQLKAGFLGGIIAGFIAGYVARWIKSWRVPKNLRPIMPIFVIPLLSALIVGFLMIYILGNPISSAM
TAMTNWLKSMSTGNAVILAMIMGAMIAFDMGGPVNKVAFLFAAAMIGEGVYTIMGPVAVAICIPPLGMGVATLLAPNKYT
KAEKEAGYGALAMGMIGITEGAIPFAAADPLRVIPSIMVGSSIGAAIAAIGKVGDHAPHGGPIVLPVVDNKIMFIVAVLI
GIAVTALMVNALKKPVIEEVEDESEVAE

Sequences:

>Translated_348_residues
MKEELKRIREYLMTGVSYMIPIVVIGGVLIAFSIALSGVQAGKGAVVTNPVLKSMMDIGTASFSMMVPVLAGFIAFGIAD
RPGLAPGLVGGVLANQLKAGFLGGIIAGFIAGYVARWIKSWRVPKNLRPIMPIFVIPLLSALIVGFLMIYILGNPISSAM
TAMTNWLKSMSTGNAVILAMIMGAMIAFDMGGPVNKVAFLFAAAMIGEGVYTIMGPVAVAICIPPLGMGVATLLAPNKYT
KAEKEAGYGALAMGMIGITEGAIPFAAADPLRVIPSIMVGSSIGAAIAAIGKVGDHAPHGGPIVLPVVDNKIMFIVAVLI
GIAVTALMVNALKKPVIEEVEDESEVAE
>Mature_348_residues
MKEELKRIREYLMTGVSYMIPIVVIGGVLIAFSIALSGVQAGKGAVVTNPVLKSMMDIGTASFSMMVPVLAGFIAFGIAD
RPGLAPGLVGGVLANQLKAGFLGGIIAGFIAGYVARWIKSWRVPKNLRPIMPIFVIPLLSALIVGFLMIYILGNPISSAM
TAMTNWLKSMSTGNAVILAMIMGAMIAFDMGGPVNKVAFLFAAAMIGEGVYTIMGPVAVAICIPPLGMGVATLLAPNKYT
KAEKEAGYGALAMGMIGITEGAIPFAAADPLRVIPSIMVGSSIGAAIAAIGKVGDHAPHGGPIVLPVVDNKIMFIVAVLI
GIAVTALMVNALKKPVIEEVEDESEVAE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790386, Length=335, Percent_Identity=51.6417910447761, Blast_Score=303, Evalue=8e-84,
Organism=Escherichia coli, GI1788492, Length=344, Percent_Identity=44.7674418604651, Blast_Score=278, Evalue=3e-76,
Organism=Escherichia coli, GI1786951, Length=353, Percent_Identity=33.1444759206799, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI87082348, Length=287, Percent_Identity=35.191637630662, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1788729, Length=372, Percent_Identity=27.9569892473118, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 35996; Mature: 35996

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
6.9 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
6.9 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure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CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]