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The map label for this gene is manP [H]

Identifier: 167039478

GI number: 167039478

Start: 859036

End: 859485

Strand: Direct

Name: manP [H]

Synonym: Teth514_0824

Alternate gene names: 167039478

Gene position: 859036-859485 (Clockwise)

Preceding gene: 167039477

Following gene: 167039479

Centisome position: 34.96

GC content: 32.67

Gene sequence:

>450_bases
ATGCTGATAAATAAAAATCTTGTCACACTAAATCTTGAGGCAAAAACCAAAGAAGAGGCAATTACAAAATTGGCTGAGTT
AGCTCAGAAAGAAGGTAAAATAACTTCCATAGATGAATATGTAAAGAGTGTACTTGATAGAGAAAAAACATATACTACAG
GGGTGGGGAATGGAATCGCAATACCACATGGAAAATCAAAAGCTGTAAAGGAGGCGATGATAGTATTTGGTAAAACAACT
GATGGAATAGAATGGGATTCATTAGATGGCAAACCTGTCAATTTAATTTTTCTCTTAGGGGTGCCTGAAGAAAATGTGGA
TAATGTTCATCTTAAGATATTGTCACAGTTATCACGAAAATTAATGAATGATAGTTTTATTGAAATGCTAAAAAAAGCAG
TAACTGTCGAGGAAATTTTAAATGCTTTAAGTGATATCCAAGTAAGTTAA

Upstream 100 bases:

>100_bases
AGAAAATTATATAATAAACTTGAATCACCGGAATTTGTAGAAAATATAAAAAAAGCAAAAAACAGAGAAGAAATTATAAA
GTTATTGGAGGTAATTTACG

Downstream 100 bases:

>100_bases
AAATAAACAAAAATAAAATAGATAAGGAGGATAAAAATACGATGAAGGAAGAATTAAAAAGGATTAGAGAATATTTAATG
ACAGGCGTATCTTACATGAT

Product: putative PTS IIA-like nitrogen-regulatory protein PtsN

Products: NA

Alternate protein names: EIIBCA-Man; EII-Man; Mannose-specific phosphotransferase enzyme IIB component; PTS system mannose-specific EIIB component; Mannose permease IIC component; PTS system mannose-specific EIIC component; Mannose-specific phosphotransferase enzyme IIA component; PTS system mannose-specific EIIA component [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MLINKNLVTLNLEAKTKEEAITKLAELAQKEGKITSIDEYVKSVLDREKTYTTGVGNGIAIPHGKSKAVKEAMIVFGKTT
DGIEWDSLDGKPVNLIFLLGVPEENVDNVHLKILSQLSRKLMNDSFIEMLKKAVTVEEILNALSDIQVS

Sequences:

>Translated_149_residues
MLINKNLVTLNLEAKTKEEAITKLAELAQKEGKITSIDEYVKSVLDREKTYTTGVGNGIAIPHGKSKAVKEAMIVFGKTT
DGIEWDSLDGKPVNLIFLLGVPEENVDNVHLKILSQLSRKLMNDSFIEMLKKAVTVEEILNALSDIQVS
>Mature_149_residues
MLINKNLVTLNLEAKTKEEAITKLAELAQKEGKITSIDEYVKSVLDREKTYTTGVGNGIAIPHGKSKAVKEAMIVFGKTT
DGIEWDSLDGKPVNLIFLLGVPEENVDNVHLKILSQLSRKLMNDSFIEMLKKAVTVEEILNALSDIQVS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1762

COG function: function code GT; Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1786951, Length=145, Percent_Identity=33.1034482758621, Blast_Score=100, Evalue=3e-23,
Organism=Escherichia coli, GI2367327, Length=133, Percent_Identity=33.0827067669173, Blast_Score=100, Evalue=4e-23,
Organism=Escherichia coli, GI1789597, Length=147, Percent_Identity=31.2925170068027, Blast_Score=80, Evalue=4e-17,
Organism=Escherichia coli, GI1788726, Length=127, Percent_Identity=36.2204724409449, Blast_Score=67, Evalue=4e-13,
Organism=Escherichia coli, GI1790027, Length=140, Percent_Identity=32.8571428571429, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1788494, Length=131, Percent_Identity=34.3511450381679, Blast_Score=66, Evalue=8e-13,
Organism=Escherichia coli, GI48994992, Length=142, Percent_Identity=23.2394366197183, Blast_Score=60, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 16438; Mature: 16438

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLINKNLVTLNLEAKTKEEAITKLAELAQKEGKITSIDEYVKSVLDREKTYTTGVGNGIA
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCCCCEE
IPHGKSKAVKEAMIVFGKTTDGIEWDSLDGKPVNLIFLLGVPEENVDNVHLKILSQLSRK
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHH
LMNDSFIEMLKKAVTVEEILNALSDIQVS
HHCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLINKNLVTLNLEAKTKEEAITKLAELAQKEGKITSIDEYVKSVLDREKTYTTGVGNGIA
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCCCCEE
IPHGKSKAVKEAMIVFGKTTDGIEWDSLDGKPVNLIFLLGVPEENVDNVHLKILSQLSRK
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHH
LMNDSFIEMLKKAVTVEEILNALSDIQVS
HHCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]