BacMap

Definition	Thermoanaerobacter sp. X514 chromosome, complete genome.
Accession	NC_010320
Length	2,457,259

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The map label for this gene is ftsH1

Identifier: 167039447

GI number: 167039447

Start: 825601

End: 827436

Strand: Direct

Name: ftsH1

Synonym: Teth514_0793

Alternate gene names: 167039447

Gene position: 825601-827436 (Clockwise)

Preceding gene: 167039446

Following gene: 167039448

Centisome position: 33.6

GC content: 38.89

Gene sequence:

>1836_bases
TTGAACGATAATAACAAAATAATTAGAAGCATGGTGCTCTATTTATTAATATTTATAGCTATTTACGCAATGGTACAATT
GTATTCTCAAAGCACCGAACCAATAACCGATATTGATTACGGACAGCTAATAAAATACATTGATGCCAATCAAGTAAAAA
GCATTACCCTTGTGGGTAATGATGTTAAAGGTGTATTAAAAAATGGTACCGAGTTTAAGAGCCGTGTACCAGATGTAACA
AACTTTATGAGTTTTGTAAATCCTTACATTTTACAAGGAAAACTGGATTTTAAAAGTGAGCCGCAAGTAGGCCCGCCATG
GTGGGTACAAATGCTTCCTTCTCTCTTTTTAATCGTAATTTTTATCATATTTTGGTATATTTTTATGCAACAGGCACAAG
GTGGGGGAGGAAGCAAAGTGATGTCTTTTGGCAAAAGCAGAGCCAGAATGATTACAGACAAAGATAAAAGAGTAACTTTT
AATGACGTGGCGGGAGCGGATGAAGAAAAAGAAGAACTACAAGAAATTGTTGAATTTTTAAAATATCCCAAAAAGTTTCT
TGAGCTTGGAGCCAGAATACCTAAAGGGGTTCTTTTAGTAGGGCCTCCAGGTACAGGAAAAACTCTTCTCGCAAAAGCTG
TAGCAGGAGAAGCGGGGGTACCGTTTTTTAGCATCAGCGGTTCCGATTTTGTGGAGATGTTTGTCGGTGTAGGTGCTGCG
AGAGTAAGAGATTTATTTGATCAAGCCAAAAAGAATGCGCCTTGTATTGTTTTTATTGATGAAATAGATGCAGTAGGAAG
GCAAAGAGGTGCGGGTTTAGGTGGCGGACATGATGAAAGAGAGCAAACACTAAACCAGTTGTTAGTTGAAATGGATGGTT
TCAGTGTCAATGAAGGTATAATTGTGATTGCCGCAACAAACAGGCCAGATATATTAGACCCTGCTCTTTTAAGACCAGGA
AGATTTGATAGGCACATTACTGTTGGTATTCCTGATATAAAAGGAAGAGAAGAAATTTTGAAGATACATTCAAGAAATAA
GCCATTGGCTCCAGATGTATCATTGCAAGTATTGGCAAGAAGGACGCCTGGGTTTACTGGGGCCGACCTTGAAAATCTTA
TGAATGAAGCGGCTCTCTTAGCAGCAAGGAGAGGGCTTAAGCAGATAACTATGGCGGAGTTGGAAGAGGCTATAACGAGA
GTAATAGCAGGACCTGAAAAGAGAAGCAGGATTATGTCTGAAAAAGACAAGAAATTGGTGGCATACCACGAAGCGGGGCA
TGCTGTTGTAGCAAAGCTTTTGCCAAACACTCCTCCTGTCCATGAGGTAACGATAATTCCGAGAGGCAGAGCTGGAGGCT
ATACTATGCTTCTTCCCGAAGAAGATAAATATTACATGTCAAAATCTGAAATGATGGATGAGATAGTTCACCTTTTAGGT
GGACGTGTGGCAGAGAGTTTAGTGCTAAATGATATAAGTACAGGTGCACAAAATGACATTGAGAGAGCTACAAATATTGC
AAGAAAGATGGTTACAGAGTATGGCATGAGTGAAAGGTTAGGGCCCATGACTTTTGGTACTAAAAGTGAAGAAGTGTTTT
TAGGGCGGGATTTAGGAAGAACAAGAAATTATAGTGAAGAAGTAGCTGCAGAAATTGATAGAGAGATAAAGAGAATAATT
GAAGAAGCGTATAAAAGAGCAGAATCATTGTTAAAGGAAAATATTGATAAACTCCACAGAGTAGCAAAAGCTCTTATTGA
AAAAGAAAAGCTTAATGGGGAAGAGTTTGAAAAAGTCTTTAACGGAGAGGATATAGAAGGGGTGCAGTTTGCATAA

Upstream 100 bases:

>100_bases
GGGTTTTAAAGCCAGAGCTGTACAAATGATTTGGTTTTTTAAAGGAGATATGATATTATAGATTAAAGGTAGTTGGACTT
GTTTGAAGGAGGGGCCTTAT

Downstream 100 bases:

>100_bases
AACACCAAATAATGTATAAGTCTTTGGACTTATACATTATTTTTTTAAAAATTTTTAGTTAACAATAAAAAAATTATTGA
CAAAAAGGAGGATTTTTCTA

Product: ATP-dependent metalloprotease FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MNDNNKIIRSMVLYLLIFIAIYAMVQLYSQSTEPITDIDYGQLIKYIDANQVKSITLVGNDVKGVLKNGTEFKSRVPDVT
NFMSFVNPYILQGKLDFKSEPQVGPPWWVQMLPSLFLIVIFIIFWYIFMQQAQGGGGSKVMSFGKSRARMITDKDKRVTF
NDVAGADEEKEELQEIVEFLKYPKKFLELGARIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGAA
RVRDLFDQAKKNAPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFSVNEGIIVIAATNRPDILDPALLRPG
RFDRHITVGIPDIKGREEILKIHSRNKPLAPDVSLQVLARRTPGFTGADLENLMNEAALLAARRGLKQITMAELEEAITR
VIAGPEKRSRIMSEKDKKLVAYHEAGHAVVAKLLPNTPPVHEVTIIPRGRAGGYTMLLPEEDKYYMSKSEMMDEIVHLLG
GRVAESLVLNDISTGAQNDIERATNIARKMVTEYGMSERLGPMTFGTKSEEVFLGRDLGRTRNYSEEVAAEIDREIKRII
EEAYKRAESLLKENIDKLHRVAKALIEKEKLNGEEFEKVFNGEDIEGVQFA

Sequences:

>Translated_611_residues
MNDNNKIIRSMVLYLLIFIAIYAMVQLYSQSTEPITDIDYGQLIKYIDANQVKSITLVGNDVKGVLKNGTEFKSRVPDVT
NFMSFVNPYILQGKLDFKSEPQVGPPWWVQMLPSLFLIVIFIIFWYIFMQQAQGGGGSKVMSFGKSRARMITDKDKRVTF
NDVAGADEEKEELQEIVEFLKYPKKFLELGARIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGAA
RVRDLFDQAKKNAPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFSVNEGIIVIAATNRPDILDPALLRPG
RFDRHITVGIPDIKGREEILKIHSRNKPLAPDVSLQVLARRTPGFTGADLENLMNEAALLAARRGLKQITMAELEEAITR
VIAGPEKRSRIMSEKDKKLVAYHEAGHAVVAKLLPNTPPVHEVTIIPRGRAGGYTMLLPEEDKYYMSKSEMMDEIVHLLG
GRVAESLVLNDISTGAQNDIERATNIARKMVTEYGMSERLGPMTFGTKSEEVFLGRDLGRTRNYSEEVAAEIDREIKRII
EEAYKRAESLLKENIDKLHRVAKALIEKEKLNGEEFEKVFNGEDIEGVQFA
>Mature_611_residues
MNDNNKIIRSMVLYLLIFIAIYAMVQLYSQSTEPITDIDYGQLIKYIDANQVKSITLVGNDVKGVLKNGTEFKSRVPDVT
NFMSFVNPYILQGKLDFKSEPQVGPPWWVQMLPSLFLIVIFIIFWYIFMQQAQGGGGSKVMSFGKSRARMITDKDKRVTF
NDVAGADEEKEELQEIVEFLKYPKKFLELGARIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGAA
RVRDLFDQAKKNAPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFSVNEGIIVIAATNRPDILDPALLRPG
RFDRHITVGIPDIKGREEILKIHSRNKPLAPDVSLQVLARRTPGFTGADLENLMNEAALLAARRGLKQITMAELEEAITR
VIAGPEKRSRIMSEKDKKLVAYHEAGHAVVAKLLPNTPPVHEVTIIPRGRAGGYTMLLPEEDKYYMSKSEMMDEIVHLLG
GRVAESLVLNDISTGAQNDIERATNIARKMVTEYGMSERLGPMTFGTKSEEVFLGRDLGRTRNYSEEVAAEIDREIKRII
EEAYKRAESLLKENIDKLHRVAKALIEKEKLNGEEFEKVFNGEDIEGVQFA

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein; Cytoplasmic side

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family

Homologues:

Organism=Homo sapiens, GI300192933, Length=495, Percent_Identity=49.4949494949495, Blast_Score=458, Evalue=1e-129,
Organism=Homo sapiens, GI7657689, Length=453, Percent_Identity=48.3443708609272, Blast_Score=428, Evalue=1e-120,
Organism=Homo sapiens, GI21327685, Length=453, Percent_Identity=48.3443708609272, Blast_Score=428, Evalue=1e-120,
Organism=Homo sapiens, GI4507173, Length=485, Percent_Identity=44.9484536082474, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI4506209, Length=246, Percent_Identity=45.5284552845528, Blast_Score=222, Evalue=9e-58,
Organism=Homo sapiens, GI6005942, Length=226, Percent_Identity=47.3451327433628, Blast_Score=215, Evalue=8e-56,
Organism=Homo sapiens, GI21361144, Length=252, Percent_Identity=46.031746031746, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI24497435, Length=254, Percent_Identity=44.0944881889764, Blast_Score=212, Evalue=1e-54,
Organism=Homo sapiens, GI24430151, Length=254, Percent_Identity=41.7322834645669, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI45643123, Length=275, Percent_Identity=40.7272727272727, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI45643125, Length=275, Percent_Identity=40.7272727272727, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI195539395, Length=245, Percent_Identity=40, Blast_Score=193, Evalue=5e-49,
Organism=Homo sapiens, GI89064750, Length=259, Percent_Identity=39.7683397683398, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI5729991, Length=259, Percent_Identity=39.7683397683398, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI24430155, Length=259, Percent_Identity=39.7683397683398, Blast_Score=189, Evalue=8e-48,
Organism=Homo sapiens, GI157671927, Length=225, Percent_Identity=43.1111111111111, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI40806173, Length=185, Percent_Identity=52.4324324324324, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI229577436, Length=259, Percent_Identity=41.6988416988417, Blast_Score=186, Evalue=7e-47,
Organism=Homo sapiens, GI4505725, Length=229, Percent_Identity=41.4847161572052, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI24497618, Length=244, Percent_Identity=43.0327868852459, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI153792536, Length=242, Percent_Identity=42.5619834710744, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI14149767, Length=254, Percent_Identity=38.1889763779528, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI62177112, Length=254, Percent_Identity=38.1889763779528, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI5901990, Length=254, Percent_Identity=40.1574803149606, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI194018488, Length=235, Percent_Identity=43.4042553191489, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI226371754, Length=259, Percent_Identity=36.6795366795367, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI156564401, Length=234, Percent_Identity=39.3162393162393, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI7019569, Length=237, Percent_Identity=37.1308016877637, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI40806170, Length=234, Percent_Identity=41.025641025641, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI11875211, Length=234, Percent_Identity=41.025641025641, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI17865802, Length=239, Percent_Identity=39.7489539748954, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI31377644, Length=243, Percent_Identity=38.2716049382716, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI31742536, Length=257, Percent_Identity=34.6303501945525, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI112789543, Length=257, Percent_Identity=34.6303501945525, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI310125280, Length=231, Percent_Identity=38.961038961039, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI310125282, Length=234, Percent_Identity=38.8888888888889, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI64084766, Length=259, Percent_Identity=27.7992277992278, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI116292174, Length=282, Percent_Identity=29.0780141843972, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI4757852, Length=166, Percent_Identity=31.3253012048193, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI119964730, Length=166, Percent_Identity=31.3253012048193, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789568, Length=601, Percent_Identity=51.7470881863561, Blast_Score=640, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71994521, Length=457, Percent_Identity=51.6411378555799, Blast_Score=448, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17554264, Length=443, Percent_Identity=48.7584650112867, Blast_Score=411, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI115534323, Length=455, Percent_Identity=46.8131868131868, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17554786, Length=254, Percent_Identity=45.2755905511811, Blast_Score=221, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17563248, Length=253, Percent_Identity=44.6640316205534, Blast_Score=219, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI17532375, Length=239, Percent_Identity=43.0962343096234, Blast_Score=216, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI25144278, Length=254, Percent_Identity=44.8818897637795, Blast_Score=215, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI25144281, Length=254, Percent_Identity=44.8818897637795, Blast_Score=215, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI17508701, Length=252, Percent_Identity=44.047619047619, Blast_Score=205, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI17531535, Length=233, Percent_Identity=44.6351931330472, Blast_Score=202, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17563250, Length=254, Percent_Identity=42.5196850393701, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71987364, Length=227, Percent_Identity=44.4933920704846, Blast_Score=198, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI71987372, Length=227, Percent_Identity=44.4933920704846, Blast_Score=197, Evalue=9e-51,
Organism=Caenorhabditis elegans, GI17505546, Length=251, Percent_Identity=42.2310756972112, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17508053, Length=253, Percent_Identity=40.3162055335968, Blast_Score=183, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17554784, Length=251, Percent_Identity=39.4422310756972, Blast_Score=176, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17537217, Length=282, Percent_Identity=37.5886524822695, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI25153574, Length=265, Percent_Identity=36.9811320754717, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI133931034, Length=248, Percent_Identity=41.1290322580645, Blast_Score=169, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI193206116, Length=248, Percent_Identity=41.1290322580645, Blast_Score=169, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI193206114, Length=248, Percent_Identity=41.1290322580645, Blast_Score=169, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI193209502, Length=262, Percent_Identity=37.0229007633588, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17570397, Length=159, Percent_Identity=50.314465408805, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI32566590, Length=159, Percent_Identity=50.314465408805, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI86561515, Length=232, Percent_Identity=39.6551724137931, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI133901658, Length=263, Percent_Identity=37.2623574144487, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI133901662, Length=262, Percent_Identity=36.6412213740458, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17562804, Length=249, Percent_Identity=34.136546184739, Blast_Score=135, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI32563584, Length=249, Percent_Identity=37.7510040160643, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17508421, Length=263, Percent_Identity=37.2623574144487, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25146157, Length=233, Percent_Identity=41.2017167381974, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17541224, Length=228, Percent_Identity=35.0877192982456, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17541226, Length=228, Percent_Identity=35.0877192982456, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17560432, Length=231, Percent_Identity=36.3636363636364, Blast_Score=118, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI71990294, Length=198, Percent_Identity=30.3030303030303, Blast_Score=76, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323736, Length=494, Percent_Identity=47.9757085020243, Blast_Score=454, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6320854, Length=466, Percent_Identity=49.5708154506438, Blast_Score=452, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6325281, Length=511, Percent_Identity=42.0743639921722, Blast_Score=405, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6322704, Length=261, Percent_Identity=42.5287356321839, Blast_Score=214, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6321390, Length=254, Percent_Identity=42.9133858267717, Blast_Score=214, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6320077, Length=242, Percent_Identity=44.2148760330579, Blast_Score=212, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6324691, Length=259, Percent_Identity=44.015444015444, Blast_Score=210, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6320197, Length=254, Percent_Identity=41.7322834645669, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324833, Length=245, Percent_Identity=42.4489795918367, Blast_Score=196, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6320602, Length=244, Percent_Identity=43.0327868852459, Blast_Score=187, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6324000, Length=286, Percent_Identity=38.8111888111888, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6323429, Length=252, Percent_Identity=39.6825396825397, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6321709, Length=243, Percent_Identity=41.5637860082305, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6322994, Length=232, Percent_Identity=42.6724137931034, Blast_Score=173, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6322651, Length=251, Percent_Identity=36.6533864541833, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6325431, Length=262, Percent_Identity=35.4961832061069, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6321465, Length=247, Percent_Identity=36.4372469635627, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319554, Length=218, Percent_Identity=37.1559633027523, Blast_Score=130, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6325183, Length=241, Percent_Identity=35.6846473029046, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320887, Length=251, Percent_Identity=33.8645418326693, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320583, Length=193, Percent_Identity=29.5336787564767, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24665814, Length=452, Percent_Identity=50.6637168141593, Blast_Score=452, Evalue=1e-127,
Organism=Drosophila melanogaster, GI28574878, Length=454, Percent_Identity=50.6607929515419, Blast_Score=452, Evalue=1e-127,
Organism=Drosophila melanogaster, GI24639391, Length=447, Percent_Identity=49.4407158836689, Blast_Score=424, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24658770, Length=498, Percent_Identity=44.7791164658635, Blast_Score=422, Evalue=1e-118,
Organism=Drosophila melanogaster, GI17137560, Length=241, Percent_Identity=44.3983402489627, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI161076486, Length=241, Percent_Identity=44.3983402489627, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI161076488, Length=241, Percent_Identity=44.3983402489627, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI17137738, Length=246, Percent_Identity=45.9349593495935, Blast_Score=222, Evalue=6e-58,
Organism=Drosophila melanogaster, GI19920408, Length=254, Percent_Identity=44.0944881889764, Blast_Score=212, Evalue=5e-55,
Organism=Drosophila melanogaster, GI45554047, Length=170, Percent_Identity=59.4117647058824, Blast_Score=210, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24660075, Length=252, Percent_Identity=44.4444444444444, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI281365776, Length=252, Percent_Identity=44.4444444444444, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI45552965, Length=252, Percent_Identity=44.4444444444444, Blast_Score=208, Evalue=7e-54,
Organism=Drosophila melanogaster, GI17738151, Length=252, Percent_Identity=45.2380952380952, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24651451, Length=254, Percent_Identity=43.3070866141732, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24649446, Length=254, Percent_Identity=42.1259842519685, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24652279, Length=203, Percent_Identity=45.8128078817734, Blast_Score=195, Evalue=7e-50,
Organism=Drosophila melanogaster, GI24640100, Length=245, Percent_Identity=40.8163265306122, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI19921202, Length=239, Percent_Identity=42.6778242677824, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24656825, Length=271, Percent_Identity=40.2214022140221, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24656820, Length=271, Percent_Identity=40.2214022140221, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI18860063, Length=232, Percent_Identity=41.8103448275862, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24663015, Length=255, Percent_Identity=38.0392156862745, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI281361487, Length=262, Percent_Identity=37.7862595419847, Blast_Score=183, Evalue=4e-46,
Organism=Drosophila melanogaster, GI281363136, Length=241, Percent_Identity=39.8340248962656, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI78707192, Length=241, Percent_Identity=39.8340248962656, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI21355121, Length=219, Percent_Identity=36.986301369863, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24644145, Length=263, Percent_Identity=37.6425855513308, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI20129529, Length=281, Percent_Identity=34.5195729537367, Blast_Score=153, Evalue=4e-37,
Organism=Drosophila melanogaster, GI281360136, Length=262, Percent_Identity=36.2595419847328, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24644411, Length=262, Percent_Identity=36.2595419847328, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI281360144, Length=262, Percent_Identity=36.2595419847328, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI281360140, Length=262, Percent_Identity=36.2595419847328, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI281360146, Length=255, Percent_Identity=36.8627450980392, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI281360138, Length=255, Percent_Identity=36.8627450980392, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI281360142, Length=255, Percent_Identity=36.8627450980392, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI21357333, Length=255, Percent_Identity=36.8627450980392, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI18859657, Length=233, Percent_Identity=39.4849785407725, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI28571849, Length=235, Percent_Identity=40.4255319148936, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28571847, Length=235, Percent_Identity=40.4255319148936, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24581396, Length=291, Percent_Identity=36.7697594501718, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI20129423, Length=248, Percent_Identity=35.0806451612903, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI17864540, Length=265, Percent_Identity=35.4716981132075, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28573010, Length=224, Percent_Identity=39.2857142857143, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24639486, Length=288, Percent_Identity=30.5555555555556, Blast_Score=105, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSH1_THEPX (B0K5A3)

Other databases:

- EMBL:   CP000923
- RefSeq:   YP_001662432.1
- ProteinModelPortal:   B0K5A3
- SMR:   B0K5A3
- MEROPS:   M41.021
- GeneID:   5877157
- GenomeReviews:   CP000923_GR
- KEGG:   tex:Teth514_0793
- HOGENOM:   HBG724153
- OMA:   QDEIFLG
- ProtClustDB:   CLSK901683
- BioCyc:   TSP1755:TETH514_0793-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01458
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642
- SMART:   SM00382
- TIGRFAMs:   TIGR01241

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41

EC number: 3.4.24.-

Molecular weight: Translated: 68036; Mature: 68036

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00674 AAA

Important sites: ACT_SITE 424-424

Signals:

None

Transmembrane regions:

HASH(0x16502ab4)-; HASH(0x18d5104c)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDNNKIIRSMVLYLLIFIAIYAMVQLYSQSTEPITDIDYGQLIKYIDANQVKSITLVGN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEECC
DVKGVLKNGTEFKSRVPDVTNFMSFVNPYILQGKLDFKSEPQVGPPWWVQMLPSLFLIVI
CHHHHHCCCHHHHHHCCCHHHHHHHHCHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
FIIFWYIFMQQAQGGGGSKVMSFGKSRARMITDKDKRVTFNDVAGADEEKEELQEIVEFL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHCCCCCHHHHHHHHHHHHH
KYPKKFLELGARIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGAA
HHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCHH
RVRDLFDQAKKNAPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFSVNEGI
HHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCE
IVIAATNRPDILDPALLRPGRFDRHITVGIPDIKGREEILKIHSRNKPLAPDVSLQVLAR
EEEEECCCCCCCCHHHCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHH
RTPGFTGADLENLMNEAALLAARRGLKQITMAELEEAITRVIAGPEKRSRIMSEKDKKLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEE
AYHEAGHAVVAKLLPNTPPVHEVTIIPRGRAGGYTMLLPEEDKYYMSKSEMMDEIVHLLG
EEHHCCHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
GRVAESLVLNDISTGAQNDIERATNIARKMVTEYGMSERLGPMTFGTKSEEVFLGRDLGR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCEEECCCCCC
TRNYSEEVAAEIDREIKRIIEEAYKRAESLLKENIDKLHRVAKALIEKEKLNGEEFEKVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
NGEDIEGVQFA
CCCCCCCCCCH
>Mature Secondary Structure
MNDNNKIIRSMVLYLLIFIAIYAMVQLYSQSTEPITDIDYGQLIKYIDANQVKSITLVGN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEECC
DVKGVLKNGTEFKSRVPDVTNFMSFVNPYILQGKLDFKSEPQVGPPWWVQMLPSLFLIVI
CHHHHHCCCHHHHHHCCCHHHHHHHHCHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
FIIFWYIFMQQAQGGGGSKVMSFGKSRARMITDKDKRVTFNDVAGADEEKEELQEIVEFL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHCCCCCHHHHHHHHHHHHH
KYPKKFLELGARIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGAA
HHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCHH
RVRDLFDQAKKNAPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFSVNEGI
HHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCE
IVIAATNRPDILDPALLRPGRFDRHITVGIPDIKGREEILKIHSRNKPLAPDVSLQVLAR
EEEEECCCCCCCCHHHCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHH
RTPGFTGADLENLMNEAALLAARRGLKQITMAELEEAITRVIAGPEKRSRIMSEKDKKLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEE
AYHEAGHAVVAKLLPNTPPVHEVTIIPRGRAGGYTMLLPEEDKYYMSKSEMMDEIVHLLG
EEHHCCHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
GRVAESLVLNDISTGAQNDIERATNIARKMVTEYGMSERLGPMTFGTKSEEVFLGRDLGR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCEEECCCCCC
TRNYSEEVAAEIDREIKRIIEEAYKRAESLLKENIDKLHRVAKALIEKEKLNGEEFEKVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
NGEDIEGVQFA
CCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA