Click here to switch to the map view.

The map label for this gene is yvtA [H]

Identifier: 167039249

GI number: 167039249

Start: 612581

End: 613942

Strand: Direct

Name: yvtA [H]

Synonym: Teth514_0590

Alternate gene names: 167039249

Gene position: 612581-613942 (Clockwise)

Preceding gene: 167039248

Following gene: 167039250

Centisome position: 24.93

GC content: 37.74

Gene sequence:

>1362_bases
ATGGATTACGAAAAAGACTTTGAAGATAAAATTGAAAAAAATGATCCGGAGAATGTAGTTCCTCCAGAAGAAAATGAAAA
AGAAGAGCTATATCAAACAGAAGAATTAAATAGCGAAATATTAAAAGCAGAGGAACAAAAGCAAGAGGAGTTGGAAACTA
CTGCGCCAATTCCTAAAGTGGTATTTAGAAACAACAAAAAGAGTTTGGGGAAGATGGTAAAAAGATTCAGAAAGAGAATG
TTAGCTTCTTTTATCGCAGTAGCGTTGGTGGCAGCTTTAATCGGCGGAGGAATTACAGGAACTGTAATGAAATACTATGG
AACCCAAAATGATGCGTCAGCACAAGTTGTTACAAGATATTTACCTCTAGATGCTACTTCGTCAGACGAAAGCGGTATTT
TAAATTTGATACCCAACATTTACAAAATAGTGAGCCCAGCAGTTGTAGAAATTAGTACAAGTGTTGCTTACAACTACGGT
TATAGAACTAGAGGTAGCGGTTCTGGATTTATCATAAGCTCTGATGGATACATTGTCACAAATAACCATGTAATTGACGG
AGCATCAAAAATCACAGTAAAACTTTCAGATGGAAGAAGTGCTGATGCAAAACTTGTAGGAAAAGATGATAGAACAGACC
TCGCAGTACTTAAAATAAACCTTCCTAATTTACCCATTGTAAAACTAGGAGATTCTTCCAAACTCCAACCTGGGGAATTG
GCAATTGCTATAGGCAATCCTCTTGGAGAATCCTTTGCAGGTACAGTCACAGCAGGTATAATAAGCGGACTCAACAGGAA
TCTCCAAAGTGATTATGGGCCTGTCAAACTCATACAAACAGATGCAGCTATAAATCCTGGCAACAGCGGCGGACCTCTTG
TGAACAGTAAAGCAGAAGTTATAGGTATAACAAGTGTTAAGCTCACTTCAATAGGACCAAGTATTCAAGACCCTTTTGGA
ATGTTCCAGAGCCAAGAAACTCCTGTTGAGGGTATGGGTTTTGCAATTCCAATAAACGAGGCAAAACCTATAATTGACCA
GATAATAAAACACGGCTATGTAGAAAGGCCTATGATGGGAATAGGTGCTCAAACTATTACACAACAAGATGCAGCCCGAT
ATAATTTGCCCGTAGGAGTGTATGTAGTTCAAGTTCAGCCAAATAGTGGAGCGGAAAAAGCTGGTATTCAACCAGGAGAT
GTGATAATAAAGGTTGATGGTAAAGACATTACTTCCTTTGAGGATTTACAAGGCATATTAAATAACCACAAAGTTGGAGA
TGTAATAAATGTAACAATTTGGAGAAATAGCAAAACATTTACAGTTACTGTAAAATTGCAAAGCAGCGCAAACTTTGAAT
AA

Upstream 100 bases:

>100_bases
TTTAATAAAAACTACTTAAAATCTTTACATCATGTTCATAATTTGTTAATAAAAAGGGGTTATAATTAAAAGCAAGAAAG
AACAAAAGGAGTGAGTGATT

Downstream 100 bases:

>100_bases
AACCGGCCAGTGATTTTACTGGTCGGTATTTTGTGTACTCTATAGCTTTTTTTTGTTTAATTATGTATAATTAATTTGAT
AAGGAAGGGTGGTCGTATGT

Product: 2-alkenal reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MDYEKDFEDKIEKNDPENVVPPEENEKEELYQTEELNSEILKAEEQKQEELETTAPIPKVVFRNNKKSLGKMVKRFRKRM
LASFIAVALVAALIGGGITGTVMKYYGTQNDASAQVVTRYLPLDATSSDESGILNLIPNIYKIVSPAVVEISTSVAYNYG
YRTRGSGSGFIISSDGYIVTNNHVIDGASKITVKLSDGRSADAKLVGKDDRTDLAVLKINLPNLPIVKLGDSSKLQPGEL
AIAIGNPLGESFAGTVTAGIISGLNRNLQSDYGPVKLIQTDAAINPGNSGGPLVNSKAEVIGITSVKLTSIGPSIQDPFG
MFQSQETPVEGMGFAIPINEAKPIIDQIIKHGYVERPMMGIGAQTITQQDAARYNLPVGVYVVQVQPNSGAEKAGIQPGD
VIIKVDGKDITSFEDLQGILNNHKVGDVINVTIWRNSKTFTVTVKLQSSANFE

Sequences:

>Translated_453_residues
MDYEKDFEDKIEKNDPENVVPPEENEKEELYQTEELNSEILKAEEQKQEELETTAPIPKVVFRNNKKSLGKMVKRFRKRM
LASFIAVALVAALIGGGITGTVMKYYGTQNDASAQVVTRYLPLDATSSDESGILNLIPNIYKIVSPAVVEISTSVAYNYG
YRTRGSGSGFIISSDGYIVTNNHVIDGASKITVKLSDGRSADAKLVGKDDRTDLAVLKINLPNLPIVKLGDSSKLQPGEL
AIAIGNPLGESFAGTVTAGIISGLNRNLQSDYGPVKLIQTDAAINPGNSGGPLVNSKAEVIGITSVKLTSIGPSIQDPFG
MFQSQETPVEGMGFAIPINEAKPIIDQIIKHGYVERPMMGIGAQTITQQDAARYNLPVGVYVVQVQPNSGAEKAGIQPGD
VIIKVDGKDITSFEDLQGILNNHKVGDVINVTIWRNSKTFTVTVKLQSSANFE
>Mature_453_residues
MDYEKDFEDKIEKNDPENVVPPEENEKEELYQTEELNSEILKAEEQKQEELETTAPIPKVVFRNNKKSLGKMVKRFRKRM
LASFIAVALVAALIGGGITGTVMKYYGTQNDASAQVVTRYLPLDATSSDESGILNLIPNIYKIVSPAVVEISTSVAYNYG
YRTRGSGSGFIISSDGYIVTNNHVIDGASKITVKLSDGRSADAKLVGKDDRTDLAVLKINLPNLPIVKLGDSSKLQPGEL
AIAIGNPLGESFAGTVTAGIISGLNRNLQSDYGPVKLIQTDAAINPGNSGGPLVNSKAEVIGITSVKLTSIGPSIQDPFG
MFQSQETPVEGMGFAIPINEAKPIIDQIIKHGYVERPMMGIGAQTITQQDAARYNLPVGVYVVQVQPNSGAEKAGIQPGD
VIIKVDGKDITSFEDLQGILNNHKVGDVINVTIWRNSKTFTVTVKLQSSANFE

Specific function: May be involved in processing, maturation, or secretion of extracellular enzymes [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=335, Percent_Identity=33.7313432835821, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI22129776, Length=308, Percent_Identity=35.3896103896104, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI24308541, Length=329, Percent_Identity=31.306990881459, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI7019477, Length=330, Percent_Identity=30.3030303030303, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI1786356, Length=288, Percent_Identity=43.0555555555556, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1789629, Length=343, Percent_Identity=36.734693877551, Blast_Score=198, Evalue=8e-52,
Organism=Escherichia coli, GI1789630, Length=319, Percent_Identity=39.8119122257053, Blast_Score=168, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24646839, Length=341, Percent_Identity=34.0175953079179, Blast_Score=150, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 48843; Mature: 48843

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYEKDFEDKIEKNDPENVVPPEENEKEELYQTEELNSEILKAEEQKQEELETTAPIPKV
CCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VFRNNKKSLGKMVKRFRKRMLASFIAVALVAALIGGGITGTVMKYYGTQNDASAQVVTRY
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHEEECCCCCCCCEEEEEE
LPLDATSSDESGILNLIPNIYKIVSPAVVEISTSVAYNYGYRTRGSGSGFIISSDGYIVT
ECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHEEEECCCEECCCCCEEEEECCCEEEE
NNHVIDGASKITVKLSDGRSADAKLVGKDDRTDLAVLKINLPNLPIVKLGDSSKLQPGEL
CCEEECCCCEEEEEECCCCCCCCEEECCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCE
AIAIGNPLGESFAGTVTAGIISGLNRNLQSDYGPVKLIQTDAAINPGNSGGPLVNSKAEV
EEEECCCCCCHHHHHHHHHHHHHHCHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCEE
IGITSVKLTSIGPSIQDPFGMFQSQETPVEGMGFAIPINEAKPIIDQIIKHGYVERPMMG
EEEEEEEEECCCCCCCCCHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCC
IGAQTITQQDAARYNLPVGVYVVQVQPNSGAEKAGIQPGDVIIKVDGKDITSFEDLQGIL
CCCHHHHHHHHHHCCCCEEEEEEEECCCCCCHHCCCCCCCEEEEECCCCCCCHHHHHHHH
NNHKVGDVINVTIWRNSKTFTVTVKLQSSANFE
CCCCCCCEEEEEEEECCEEEEEEEEEECCCCCC
>Mature Secondary Structure
MDYEKDFEDKIEKNDPENVVPPEENEKEELYQTEELNSEILKAEEQKQEELETTAPIPKV
CCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VFRNNKKSLGKMVKRFRKRMLASFIAVALVAALIGGGITGTVMKYYGTQNDASAQVVTRY
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHEEECCCCCCCCEEEEEE
LPLDATSSDESGILNLIPNIYKIVSPAVVEISTSVAYNYGYRTRGSGSGFIISSDGYIVT
ECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHEEEECCCEECCCCCEEEEECCCEEEE
NNHVIDGASKITVKLSDGRSADAKLVGKDDRTDLAVLKINLPNLPIVKLGDSSKLQPGEL
CCEEECCCCEEEEEECCCCCCCCEEECCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCE
AIAIGNPLGESFAGTVTAGIISGLNRNLQSDYGPVKLIQTDAAINPGNSGGPLVNSKAEV
EEEECCCCCCHHHHHHHHHHHHHHCHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCEE
IGITSVKLTSIGPSIQDPFGMFQSQETPVEGMGFAIPINEAKPIIDQIIKHGYVERPMMG
EEEEEEEEECCCCCCCCCHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCC
IGAQTITQQDAARYNLPVGVYVVQVQPNSGAEKAGIQPGDVIIKVDGKDITSFEDLQGIL
CCCHHHHHHHHHHCCCCEEEEEEEECCCCCCHHCCCCCCCEEEEECCCCCCCHHHHHHHH
NNHKVGDVINVTIWRNSKTFTVTVKLQSSANFE
CCCCCCCEEEEEEEECCEEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10692364; 9353931; 9384377; 10568751; 11133960 [H]