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The map label for this gene is walR [H]

Identifier: 167039247

GI number: 167039247

Start: 610218

End: 610901

Strand: Direct

Name: walR [H]

Synonym: Teth514_0588

Alternate gene names: 167039247

Gene position: 610218-610901 (Clockwise)

Preceding gene: 167039246

Following gene: 167039248

Centisome position: 24.83

GC content: 36.84

Gene sequence:

>684_bases
GTGGGAGATAACCGAAAGATTTATGTAGTGGATGATGACAAGAATATATGTGAAATAGTTTCTTTGTACCTTGAAAAAGA
GGGTTTTGATGTAGAGCAGATATACGATGGGCAAACCGCACTAAAGAAAATACAAGAAAAACCTCCAAAGCTCGTCATAC
TTGACATAATGTTGCCAGGAATTGATGGTATAGCTCTTTGCAGAGAAGTCAGAAAATTTTCAAAGGTGCCTATAATAATG
CTTACCGCAAAAGGGGATACACTTGATAAGGTATTGGCTTTAGAGATTGGCGCTGATGACTACATCGTAAAGCCATTTGA
CGGGAAAGAATTAGTAGCAAGAGTTAAAGCGGTTTTAAGAAGATATGAACCGGAAAGTGAGGAAAAACAGGCTGTTTCTT
ATCCAGAACTTTATGTAAGTTTAAGCGAATATAAAGTTGTTTATAAAGGGCAAAATGTAGATTTAACTCCCAAAGAGTTA
GAACTTTTATATTTCTTATGTACACATCCTAACAGGGTTTTCACGAGAGACCAGCTATTAGAAAATGTATGGGGTTATGA
TTATATGGGAGATAGTCGTACAGTAGATGTTCATATAAAGCGGCTTAGAGAGAAAATGGGAGATGGCCCTAATTGGAAAC
TTACCACCGTATGGGGTGTAGGTTATAAATTTGAGGTGAACTAA

Upstream 100 bases:

>100_bases
TAAATTGTTTGTATAGGCACTTTATGTGCCTTTTTTATATTATTTAAAATTTTATTATGATATAATTTAAGCAAGGAAAC
TTGAAGTAGAGGGTGATTTT

Downstream 100 bases:

>100_bases
ATTTGAGCAAAAATAGACTTTTTAAAAAACTTTTTATAAGCAATATGATTATCATCCTTATTACTTTGTCTATTCTTTCA
GGGATGTTTTATCTGATGTT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MGDNRKIYVVDDDKNICEIVSLYLEKEGFDVEQIYDGQTALKKIQEKPPKLVILDIMLPGIDGIALCREVRKFSKVPIIM
LTAKGDTLDKVLALEIGADDYIVKPFDGKELVARVKAVLRRYEPESEEKQAVSYPELYVSLSEYKVVYKGQNVDLTPKEL
ELLYFLCTHPNRVFTRDQLLENVWGYDYMGDSRTVDVHIKRLREKMGDGPNWKLTTVWGVGYKFEVN

Sequences:

>Translated_227_residues
MGDNRKIYVVDDDKNICEIVSLYLEKEGFDVEQIYDGQTALKKIQEKPPKLVILDIMLPGIDGIALCREVRKFSKVPIIM
LTAKGDTLDKVLALEIGADDYIVKPFDGKELVARVKAVLRRYEPESEEKQAVSYPELYVSLSEYKVVYKGQNVDLTPKEL
ELLYFLCTHPNRVFTRDQLLENVWGYDYMGDSRTVDVHIKRLREKMGDGPNWKLTTVWGVGYKFEVN
>Mature_226_residues
GDNRKIYVVDDDKNICEIVSLYLEKEGFDVEQIYDGQTALKKIQEKPPKLVILDIMLPGIDGIALCREVRKFSKVPIIML
TAKGDTLDKVLALEIGADDYIVKPFDGKELVARVKAVLRRYEPESEEKQAVSYPELYVSLSEYKVVYKGQNVDLTPKELE
LLYFLCTHPNRVFTRDQLLENVWGYDYMGDSRTVDVHIKRLREKMGDGPNWKLTTVWGVGYKFEVN

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=40.1785714285714, Blast_Score=184, Evalue=4e-48,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=41.9642857142857, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=37.9310344827586, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=38.4955752212389, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=34.6846846846847, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=34.0909090909091, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=38.5650224215247, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=34.841628959276, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=34.6491228070175, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=32.7354260089686, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=34.7826086956522, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=31.8181818181818, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=32.1428571428571, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=31.8385650224215, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=35.3448275862069, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=32.258064516129, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1790437, Length=136, Percent_Identity=32.3529411764706, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26161; Mature: 26029

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDNRKIYVVDDDKNICEIVSLYLEKEGFDVEQIYDGQTALKKIQEKPPKLVILDIMLPG
CCCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHCCCCEEEEEEECCC
IDGIALCREVRKFSKVPIIMLTAKGDTLDKVLALEIGADDYIVKPFDGKELVARVKAVLR
CCHHHHHHHHHHHCCCCEEEEEECCCCHHHEEEEEECCCCEEECCCCCHHHHHHHHHHHH
RYEPESEEKQAVSYPELYVSLSEYKVVYKGQNVDLTPKELELLYFLCTHPNRVFTRDQLL
HCCCCCCHHHHCCCHHHEEEHHHEEEEEECCCCCCCHHHEEEEEEEECCCCCCCCHHHHH
ENVWGYDYMGDSRTVDVHIKRLREKMGDGPNWKLTTVWGVGYKFEVN
HHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEEEEEEECCEEEEEC
>Mature Secondary Structure 
GDNRKIYVVDDDKNICEIVSLYLEKEGFDVEQIYDGQTALKKIQEKPPKLVILDIMLPG
CCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHCCCCEEEEEEECCC
IDGIALCREVRKFSKVPIIMLTAKGDTLDKVLALEIGADDYIVKPFDGKELVARVKAVLR
CCHHHHHHHHHHHCCCCEEEEEECCCCHHHEEEEEECCCCEEECCCCCHHHHHHHHHHHH
RYEPESEEKQAVSYPELYVSLSEYKVVYKGQNVDLTPKELELLYFLCTHPNRVFTRDQLL
HCCCCCCHHHHCCCHHHEEEHHHEEEEEECCCCCCCHHHEEEEEEEECCCCCCCCHHHHH
ENVWGYDYMGDSRTVDVHIKRLREKMGDGPNWKLTTVWGVGYKFEVN
HHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEEEEEEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA