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The map label for this gene is fruA [H]

Identifier: 167039236

GI number: 167039236

Start: 600060

End: 600506

Strand: Direct

Name: fruA [H]

Synonym: Teth514_0577

Alternate gene names: 167039236

Gene position: 600060-600506 (Clockwise)

Preceding gene: 167039235

Following gene: 167039237

Centisome position: 24.42

GC content: 37.58

Gene sequence:

>447_bases
ATGGAAATAAAAGATGTATTGAACGAAAAAATGATGGTTTTTGACCTAAAGGCAAAGGACAAAAATGGAGTGTTGGAAGA
GTTAGTAAGTGTTTTAAAAGAAAATGGAGTTGTAGATGATGAAGAAGGCTTTTTAGAAGTGGTGAAAAAAAGAGAAGAGG
AGTTTTCTACAGGTATAGGTTATGGGGTTGCAATACCTCATGGCAAAAGCAGTCTTGTGAAAAAGCCAGCAATAGTATTT
GGAAAGTCTCGACAAGGAATAGACTATAACTCAATGGATGGCAAACCTGCCTATTTATTTTTCTTAATTGCTGTGCCAGA
CAACTCTGATGAGCTGCACCTTAAAGTTTTGGCTGAGCTTTCAAGGTCTTTAATGCATAAGGAGGTGAGAGAGGAGTTAG
AAAAAGCGTCGACACCTGAGGAAGTCATAAAGGCTTTTGAGAAGTAA

Upstream 100 bases:

>100_bases
CCTCCGTTGTCATGAAAGAAGGCACAAGAGCAGGCACTCTTGAGGAGGTAAATATATTAAAGGATAAGATTGGAATAGAG
AGGATAGAAAGGTGAGGGAA

Downstream 100 bases:

>100_bases
AATCTTTATGAAAGGGGATTGTTATGAAAAAGATAGTTGCTGTTACAGCCTGCCCTACAGGTATTGCCCATACCTATATG
GCGGCGGAAAATCTTCAGAT

Product: putative PTS IIA-like nitrogen-regulatory protein PtsN

Products: NA

Alternate protein names: EIIABC-Fru; Fructose-specific phosphotransferase enzyme IIA component; EII-Fru; PTS system fructose-specific EIIA component; Fructose-specific phosphotransferase enzyme IIB component; EIII-Fru; PTS system fructose-specific EIIB component; Fructose permease IIC component; PTS system fructose-specific EIIC component [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MEIKDVLNEKMMVFDLKAKDKNGVLEELVSVLKENGVVDDEEGFLEVVKKREEEFSTGIGYGVAIPHGKSSLVKKPAIVF
GKSRQGIDYNSMDGKPAYLFFLIAVPDNSDELHLKVLAELSRSLMHKEVREELEKASTPEEVIKAFEK

Sequences:

>Translated_148_residues
MEIKDVLNEKMMVFDLKAKDKNGVLEELVSVLKENGVVDDEEGFLEVVKKREEEFSTGIGYGVAIPHGKSSLVKKPAIVF
GKSRQGIDYNSMDGKPAYLFFLIAVPDNSDELHLKVLAELSRSLMHKEVREELEKASTPEEVIKAFEK
>Mature_148_residues
MEIKDVLNEKMMVFDLKAKDKNGVLEELVSVLKENGVVDDEEGFLEVVKKREEEFSTGIGYGVAIPHGKSSLVKKPAIVF
GKSRQGIDYNSMDGKPAYLFFLIAVPDNSDELHLKVLAELSRSLMHKEVREELEKASTPEEVIKAFEK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1762

COG function: function code GT; Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI2367327, Length=134, Percent_Identity=32.089552238806, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI1786951, Length=149, Percent_Identity=27.5167785234899, Blast_Score=75, Evalue=1e-15,
Organism=Escherichia coli, GI1789597, Length=143, Percent_Identity=29.3706293706294, Blast_Score=63, Evalue=6e-12,
Organism=Escherichia coli, GI1788726, Length=146, Percent_Identity=27.3972602739726, Blast_Score=63, Evalue=8e-12,
Organism=Escherichia coli, GI1788494, Length=129, Percent_Identity=34.1085271317829, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 16627; Mature: 16627

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKDVLNEKMMVFDLKAKDKNGVLEELVSVLKENGVVDDEEGFLEVVKKREEEFSTGIG
CCCHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
YGVAIPHGKSSLVKKPAIVFGKSRQGIDYNSMDGKPAYLFFLIAVPDNSDELHLKVLAEL
CEEECCCCCHHHHHCCHHEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHH
SRSLMHKEVREELEKASTPEEVIKAFEK
HHHHHHHHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MEIKDVLNEKMMVFDLKAKDKNGVLEELVSVLKENGVVDDEEGFLEVVKKREEEFSTGIG
CCCHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
YGVAIPHGKSSLVKKPAIVFGKSRQGIDYNSMDGKPAYLFFLIAVPDNSDELHLKVLAEL
CEEECCCCCHHHHHCCHHEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHH
SRSLMHKEVREELEKASTPEEVIKAFEK
HHHHHHHHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]