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The map label for this gene is adhB [H]

Identifier: 167039223

GI number: 167039223

Start: 588109

End: 589308

Strand: Direct

Name: adhB [H]

Synonym: Teth514_0564

Alternate gene names: 167039223

Gene position: 588109-589308 (Clockwise)

Preceding gene: 167039221

Following gene: 167039224

Centisome position: 23.93

GC content: 42.42

Gene sequence:

>1200_bases
GTGTGGGAAACAAAAATAAATCCAAATAAGGTTTTTGAACTTCGCTGCAAAAACACGACTTATTTTGGAATAGGTAGTAT
AAAAAAGATAAAAGATATTCTAGAAGTTCTTAAAAACAAAGGTATCAACAATGTCATTCTTGTAACCGGTAAAGGTTCCT
ATAAAGCCAGTGGGGCCTGGGATGTGGTAAAACCGGCTCTTGAGACACTCGGATTCAAATATTCACTTTATGACAAGGTT
GGGCCCAATCCTACTGTTGACATGATCGATGAGGCGGCCAAAATCGGCCGGGAAACTGGGGCAAAAGCTGTTATCGGCAT
TGGCGGTGGCAGCCCTATAGATACCGCGAAAAGTGTGGCTGTACTGCTGGAATACACTGATAAAAATGCAAGAGAACTTT
ATGAACAGAAATTCATACCTGAAAAAGCTGCTCCTATTATAGCTATAAACCTTACTCATGGTACTGGTACCGAAGTAGAC
AGATTTGCGGTGGCTACCATCCCAGAAAAAAATTATAAGCCTGCAATTGCTTATGATTGCCTGTATCCTATGTATGCCAT
AGATGACCCTTCCCTTATGACAAAGCTTGACAAAAAACAGACAATAGCGGTTACTATAGATGCTTTAAACCACGTTACCG
AAGCTGCTACCACTCTTGTAGCGTCACCTTACAGCGTCCTAATGGCAAAAGAAACAGTGAGGCTGATAGTTCGTTACCTA
CCCGCTGCTGTAAATGACCCTGAAAACCTTGTGGCCAGATACTATTTGCTTTACGCTTCTGCTTTAGCTGGTATTTCTTT
TGACAATGGCCTTTTGCACCTTACCCATGCGCTAGAGCATCCTCTGAGTGCAGTAAAACCCGAGATAGCTCATGGTCTTG
GACTTGGTGCTATACTGCCTGCGGTGGTAAAGGCTATTTATCCATCTGTTGCAGAAGTTCTGGCTGAAGTATATAGTCCT
ATAGTGCCTGGGCTAAAAGGTCTGCCTGCTGAAGCAGAATATGTAGCTAAAAAGGTTGAAGAATGGCTCTTTAAGGTAGG
ATGCACCCAAAAACTTTCGGACTTTGGATTCACAAAAGAGGATATTCCGACTCTGGTAAGGCTTGCTAAAACTACGCCTT
CTCTGGACGGATTGCTTTCTAATGCACCAGTGGAAGCAACTGAAGCTGTTATTGCCAAGATTTATGAAGAATCTTTCTAA

Upstream 100 bases:

>100_bases
ATAAGAATAGATATTATAACTTGGGGTTGACCATTTTCTAAGATAGTGCTATAATTGTATACAGAGATTGTTATAAATTT
AACAATAGGAGGTAATTAAA

Downstream 100 bases:

>100_bases
AATTTAATTTAAAAATTTCACAGCAAGCAGATAGACAATAGGCAATGAACAAGAACAGTATAGTTATTATTTTAACCATG
TTGAAGGCAAAGAAATTTTA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: Alcohol dehydrogenase II; ADH II [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MWETKINPNKVFELRCKNTTYFGIGSIKKIKDILEVLKNKGINNVILVTGKGSYKASGAWDVVKPALETLGFKYSLYDKV
GPNPTVDMIDEAAKIGRETGAKAVIGIGGGSPIDTAKSVAVLLEYTDKNARELYEQKFIPEKAAPIIAINLTHGTGTEVD
RFAVATIPEKNYKPAIAYDCLYPMYAIDDPSLMTKLDKKQTIAVTIDALNHVTEAATTLVASPYSVLMAKETVRLIVRYL
PAAVNDPENLVARYYLLYASALAGISFDNGLLHLTHALEHPLSAVKPEIAHGLGLGAILPAVVKAIYPSVAEVLAEVYSP
IVPGLKGLPAEAEYVAKKVEEWLFKVGCTQKLSDFGFTKEDIPTLVRLAKTTPSLDGLLSNAPVEATEAVIAKIYEESF

Sequences:

>Translated_399_residues
MWETKINPNKVFELRCKNTTYFGIGSIKKIKDILEVLKNKGINNVILVTGKGSYKASGAWDVVKPALETLGFKYSLYDKV
GPNPTVDMIDEAAKIGRETGAKAVIGIGGGSPIDTAKSVAVLLEYTDKNARELYEQKFIPEKAAPIIAINLTHGTGTEVD
RFAVATIPEKNYKPAIAYDCLYPMYAIDDPSLMTKLDKKQTIAVTIDALNHVTEAATTLVASPYSVLMAKETVRLIVRYL
PAAVNDPENLVARYYLLYASALAGISFDNGLLHLTHALEHPLSAVKPEIAHGLGLGAILPAVVKAIYPSVAEVLAEVYSP
IVPGLKGLPAEAEYVAKKVEEWLFKVGCTQKLSDFGFTKEDIPTLVRLAKTTPSLDGLLSNAPVEATEAVIAKIYEESF
>Mature_399_residues
MWETKINPNKVFELRCKNTTYFGIGSIKKIKDILEVLKNKGINNVILVTGKGSYKASGAWDVVKPALETLGFKYSLYDKV
GPNPTVDMIDEAAKIGRETGAKAVIGIGGGSPIDTAKSVAVLLEYTDKNARELYEQKFIPEKAAPIIAINLTHGTGTEVD
RFAVATIPEKNYKPAIAYDCLYPMYAIDDPSLMTKLDKKQTIAVTIDALNHVTEAATTLVASPYSVLMAKETVRLIVRYL
PAAVNDPENLVARYYLLYASALAGISFDNGLLHLTHALEHPLSAVKPEIAHGLGLGAILPAVVKAIYPSVAEVLAEVYSP
IVPGLKGLPAEAEYVAKKVEEWLFKVGCTQKLSDFGFTKEDIPTLVRLAKTTPSLDGLLSNAPVEATEAVIAKIYEESF

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=430, Percent_Identity=25.8139534883721, Blast_Score=105, Evalue=8e-23,
Organism=Escherichia coli, GI48994951, Length=376, Percent_Identity=30.5851063829787, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI87082107, Length=355, Percent_Identity=28.4507042253521, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1789163, Length=391, Percent_Identity=28.9002557544757, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787493, Length=297, Percent_Identity=29.2929292929293, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789386, Length=373, Percent_Identity=25.7372654155496, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17537053, Length=433, Percent_Identity=26.0969976905312, Blast_Score=123, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321181, Length=386, Percent_Identity=31.3471502590674, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24657991, Length=407, Percent_Identity=28.7469287469287, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 43242; Mature: 43242

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWETKINPNKVFELRCKNTTYFGIGSIKKIKDILEVLKNKGINNVILVTGKGSYKASGAW
CCCCCCCCCCEEEEEECCCEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCH
DVVKPALETLGFKYSLYDKVGPNPTVDMIDEAAKIGRETGAKAVIGIGGGSPIDTAKSVA
HHHHHHHHHHCCEEEEHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHH
VLLEYTDKNARELYEQKFIPEKAAPIIAINLTHGTGTEVDRFAVATIPEKNYKPAIAYDC
HHEEECCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHEEEEECCCCCCCCCEEHHH
LYPMYAIDDPSLMTKLDKKQTIAVTIDALNHVTEAATTLVASPYSVLMAKETVRLIVRYL
HCCHHCCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
PAAVNDPENLVARYYLLYASALAGISFDNGLLHLTHALEHPLSAVKPEIAHGLGLGAILP
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHCHHHHHCCCHHHHHH
AVVKAIYPSVAEVLAEVYSPIVPGLKGLPAEAEYVAKKVEEWLFKVGCTQKLSDFGFTKE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCHH
DIPTLVRLAKTTPSLDGLLSNAPVEATEAVIAKIYEESF
HHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWETKINPNKVFELRCKNTTYFGIGSIKKIKDILEVLKNKGINNVILVTGKGSYKASGAW
CCCCCCCCCCEEEEEECCCEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCH
DVVKPALETLGFKYSLYDKVGPNPTVDMIDEAAKIGRETGAKAVIGIGGGSPIDTAKSVA
HHHHHHHHHHCCEEEEHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHH
VLLEYTDKNARELYEQKFIPEKAAPIIAINLTHGTGTEVDRFAVATIPEKNYKPAIAYDC
HHEEECCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHEEEEECCCCCCCCCEEHHH
LYPMYAIDDPSLMTKLDKKQTIAVTIDALNHVTEAATTLVASPYSVLMAKETVRLIVRYL
HCCHHCCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
PAAVNDPENLVARYYLLYASALAGISFDNGLLHLTHALEHPLSAVKPEIAHGLGLGAILP
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHCHHHHHCCCHHHHHH
AVVKAIYPSVAEVLAEVYSPIVPGLKGLPAEAEYVAKKVEEWLFKVGCTQKLSDFGFTKE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCHH
DIPTLVRLAKTTPSLDGLLSNAPVEATEAVIAKIYEESF
HHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3584063; 2308827; 2935393 [H]