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The map label for this gene is cpkA [H]

Identifier: 167039146

GI number: 167039146

Start: 499537

End: 500478

Strand: Direct

Name: cpkA [H]

Synonym: Teth514_0485

Alternate gene names: 167039146

Gene position: 499537-500478 (Clockwise)

Preceding gene: 167039145

Following gene: 167039147

Centisome position: 20.33

GC content: 38.43

Gene sequence:

>942_bases
ATGAGGGAAAAAGTTGTTATTGCCTTAGGAGGGAACGCTCTGCAGGACGTGAATACGCCTCCTACTGCAGAGGCTCAAAT
GGAAGTAGTGAAGAGGACAGCGGGGTATTTAGTGGATATAATTGAAAAAGGGTATTCTGTTGTAATTACTCATGGCAATG
GTCCTCAGGTGGGGAATATAGTCATACAAAATGAAGTCGCATCAAAAGTTGTCCCTGCAATGCCTTTTGATGTGTGTGGG
GCAGAGAGCCAGGGTATGATAGGATATATGATTCAACAGGCATTGGGGGAAGTTTTGAAGGAGAGAAATATCAGAAAAGA
AGTAGCAACTATTATAACACAGGTTGTAGTGGATAAAAATGACCCTGCTTTTGAAAAACCTACAAAGCCGATAGGACCTT
TTTATACAAAAGAGGAAGCTGAAGTTTTAATAAAAGAAAAAGGTTATGAAATGGTGGAAGACAGTGGAAGAGGATACAGA
AGAGTTGTTCCCTCCCCTGACCCCAAAGAAATTGTAGAACTTAATACAATAAAGTTACTTGAAAAAAATGGGGTAATAGT
AATAACAGTTGGGGGAGGAGGAATCCCTGTTATTAAGGAAAATGGCAATTTAAAAGGAGTAGCTGCCGTAATAGACAAAG
ATTTGGCTTCTGAAAAATTGGCAGAAGACATTGATGCAGATGTTTTATTGATTCTTACAGCCGTTGAAAAGGTAGCGATA
AATTACAACAAGCCAAATCAAAAATTTCTTGACAAAATGACAGTGGAAGAGGCAATAAAATACATGGAAGAAGGTCATTT
TGCGCCAGGCAGTATGTTTCCTAAAGTTAAAGCAGCAGTGAGATTTGCAAATTCAAAAGTAGGAAGACGAGCAATAATTA
CTTCTTTAGACAAAGCATTAGAAGCTTTAGAAGGAAAAGCAGGCACAGTTATAAGCTTATGA

Upstream 100 bases:

>100_bases
AACAATCTAGAGTGTGGGACCAAGCAGAAAATAGAAAACATACAATTAAAGCTGTGATGATTGCTACTCTGCTTTAAAAT
TGGTTACAGGGGAGGACATT

Downstream 100 bases:

>100_bases
AAATAAATTAAAAATTTTTCACAAAAACTATTGACAAAGAGAGATAAAAGTGAGAGAATAAAGTTAAAATTGAAAAGATG
AAGGTAAATCTTCGGGGCAG

Product: carbamate kinase

Products: NA

Alternate protein names: Carbamate kinase-like carbamoylphosphate synthase [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MREKVVIALGGNALQDVNTPPTAEAQMEVVKRTAGYLVDIIEKGYSVVITHGNGPQVGNIVIQNEVASKVVPAMPFDVCG
AESQGMIGYMIQQALGEVLKERNIRKEVATIITQVVVDKNDPAFEKPTKPIGPFYTKEEAEVLIKEKGYEMVEDSGRGYR
RVVPSPDPKEIVELNTIKLLEKNGVIVITVGGGGIPVIKENGNLKGVAAVIDKDLASEKLAEDIDADVLLILTAVEKVAI
NYNKPNQKFLDKMTVEEAIKYMEEGHFAPGSMFPKVKAAVRFANSKVGRRAIITSLDKALEALEGKAGTVISL

Sequences:

>Translated_313_residues
MREKVVIALGGNALQDVNTPPTAEAQMEVVKRTAGYLVDIIEKGYSVVITHGNGPQVGNIVIQNEVASKVVPAMPFDVCG
AESQGMIGYMIQQALGEVLKERNIRKEVATIITQVVVDKNDPAFEKPTKPIGPFYTKEEAEVLIKEKGYEMVEDSGRGYR
RVVPSPDPKEIVELNTIKLLEKNGVIVITVGGGGIPVIKENGNLKGVAAVIDKDLASEKLAEDIDADVLLILTAVEKVAI
NYNKPNQKFLDKMTVEEAIKYMEEGHFAPGSMFPKVKAAVRFANSKVGRRAIITSLDKALEALEGKAGTVISL
>Mature_313_residues
MREKVVIALGGNALQDVNTPPTAEAQMEVVKRTAGYLVDIIEKGYSVVITHGNGPQVGNIVIQNEVASKVVPAMPFDVCG
AESQGMIGYMIQQALGEVLKERNIRKEVATIITQVVVDKNDPAFEKPTKPIGPFYTKEEAEVLIKEKGYEMVEDSGRGYR
RVVPSPDPKEIVELNTIKLLEKNGVIVITVGGGGIPVIKENGNLKGVAAVIDKDLASEKLAEDIDADVLLILTAVEKVAI
NYNKPNQKFLDKMTVEEAIKYMEEGHFAPGSMFPKVKAAVRFANSKVGRRAIITSLDKALEALEGKAGTVISL

Specific function: Unknown

COG id: COG0549

COG function: function code E; Carbamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789238, Length=315, Percent_Identity=57.1428571428571, Blast_Score=332, Evalue=2e-92,
Organism=Escherichia coli, GI1786516, Length=315, Percent_Identity=45.3968253968254, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1786732, Length=309, Percent_Identity=42.7184466019417, Blast_Score=205, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR003964
- InterPro:   IPR023000 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.2 [H]

Molecular weight: Translated: 33868; Mature: 33868

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00850 GLY_RADICAL_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREKVVIALGGNALQDVNTPPTAEAQMEVVKRTAGYLVDIIEKGYSVVITHGNGPQVGNI
CCCEEEEEECCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEE
VIQNEVASKVVPAMPFDVCGAESQGMIGYMIQQALGEVLKERNIRKEVATIITQVVVDKN
EECCHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
DPAFEKPTKPIGPFYTKEEAEVLIKEKGYEMVEDSGRGYRRVVPSPDPKEIVELNTIKLL
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCCCEECCCCCCHHHHHHHHHEEEE
EKNGVIVITVGGGGIPVIKENGNLKGVAAVIDKDLASEKLAEDIDADVLLILTAVEKVAI
ECCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
NYNKPNQKFLDKMTVEEAIKYMEEGHFAPGSMFPKVKAAVRFANSKVGRRAIITSLDKAL
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
EALEGKAGTVISL
HHHCCCCCCEEEC
>Mature Secondary Structure
MREKVVIALGGNALQDVNTPPTAEAQMEVVKRTAGYLVDIIEKGYSVVITHGNGPQVGNI
CCCEEEEEECCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEE
VIQNEVASKVVPAMPFDVCGAESQGMIGYMIQQALGEVLKERNIRKEVATIITQVVVDKN
EECCHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
DPAFEKPTKPIGPFYTKEEAEVLIKEKGYEMVEDSGRGYRRVVPSPDPKEIVELNTIKLL
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCCCEECCCCCCHHHHHHHHHEEEE
EKNGVIVITVGGGGIPVIKENGNLKGVAAVIDKDLASEKLAEDIDADVLLILTAVEKVAI
ECCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
NYNKPNQKFLDKMTVEEAIKYMEEGHFAPGSMFPKVKAAVRFANSKVGRRAIITSLDKAL
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
EALEGKAGTVISL
HHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11523892; 12622808 [H]