Click here to switch to the map view.

The map label for this gene is argF [H]

Identifier: 167039145

GI number: 167039145

Start: 498572

End: 499513

Strand: Direct

Name: argF [H]

Synonym: Teth514_0484

Alternate gene names: 167039145

Gene position: 498572-499513 (Clockwise)

Preceding gene: 167039144

Following gene: 167039146

Centisome position: 20.29

GC content: 38.85

Gene sequence:

>942_bases
ATGGCATTTAATTTAAAGGGCAGGAGCTTATTAACTTTAAAAGATTACACCCCTCAAGAAATAAGATATATTTTAGACAT
TGCTAAACAAGTAAAAGCAGAGAGAAAAGCAGGGGTTGTACATCAAAGATTTTTAGGTAAGACTATTGCTCTCATTTTTG
AAAAGAGGTCCACAAGAACGAGATGCGCTTTTGAAACTGCCTTTGGTGAAGAAGGAGGACATCCAGTATTTTTATCAACA
GATGACATTCAGTTGGGAGCCAAAGAATCTATAGAGGATACTGCCAGAGTTTTAGGAAGGATGTTTGATGCAATAGAGTT
CAGAGGCTTCAAACAAGAAACCGTGGAAATTTTGGCAAAATATGCAGGTGTTCCTGTGTACAATGGCTTAACTGACGAAT
ATCATCCAACTCAAGTTTTGGCTGACCTTATGACAATAGAAGAAGAATTTGGGAATTTAAAAGGAAGAAAGCTTGTATTT
GTAGGGGATGGAAGGAATAACATGGCTAATACTTTAGCGGTAGGCTGCGCTAAGATGGGGATGCATTATGTGATTAATTC
TCCAAAAGAATTGTGGCCTTCACAGGAGTTCATAGATGAAATCAGGCAAATGGCAGCTGAAAATGGAGGAACTTTTGAAC
TTACTAGTGTGCCAGGAGAGGGCCTTGAAGGTGCAGATGCTATTTACACCGATGTGTGGGCGTCAATGGGAGAAGAAGCA
AAGGCTACAGAGAGGGAAGCTCTTTTGAGACCTTTTCAAGTGAATGAGGAAATGATGAAAAAGACAGGAAGAGAAGATAC
TATATTTTTGCATTGCCTGCCCGCAGTAAAAGGACAAGAAGTTACTTTTGATGTTATAGAAGGTAAACAATCTAGAGTGT
GGGACCAAGCAGAAAATAGAAAACATACAATTAAAGCTGTGATGATTGCTACTCTGCTTTAA

Upstream 100 bases:

>100_bases
ATGTCGATGCCTTTAAAGAGAGAAGATATATAAACCTTTTGACTAATAGGGTAAGATAATATAAAATTAATAAAGTAAAA
TTGCTAAAAGGAGGATGACT

Downstream 100 bases:

>100_bases
AATTGGTTACAGGGGAGGACATTATGAGGGAAAAAGTTGTTATTGCCTTAGGAGGGAACGCTCTGCAGGACGTGAATACG
CCTCCTACTGCAGAGGCTCA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MAFNLKGRSLLTLKDYTPQEIRYILDIAKQVKAERKAGVVHQRFLGKTIALIFEKRSTRTRCAFETAFGEEGGHPVFLST
DDIQLGAKESIEDTARVLGRMFDAIEFRGFKQETVEILAKYAGVPVYNGLTDEYHPTQVLADLMTIEEEFGNLKGRKLVF
VGDGRNNMANTLAVGCAKMGMHYVINSPKELWPSQEFIDEIRQMAAENGGTFELTSVPGEGLEGADAIYTDVWASMGEEA
KATEREALLRPFQVNEEMMKKTGREDTIFLHCLPAVKGQEVTFDVIEGKQSRVWDQAENRKHTIKAVMIATLL

Sequences:

>Translated_313_residues
MAFNLKGRSLLTLKDYTPQEIRYILDIAKQVKAERKAGVVHQRFLGKTIALIFEKRSTRTRCAFETAFGEEGGHPVFLST
DDIQLGAKESIEDTARVLGRMFDAIEFRGFKQETVEILAKYAGVPVYNGLTDEYHPTQVLADLMTIEEEFGNLKGRKLVF
VGDGRNNMANTLAVGCAKMGMHYVINSPKELWPSQEFIDEIRQMAAENGGTFELTSVPGEGLEGADAIYTDVWASMGEEA
KATEREALLRPFQVNEEMMKKTGREDTIFLHCLPAVKGQEVTFDVIEGKQSRVWDQAENRKHTIKAVMIATLL
>Mature_312_residues
AFNLKGRSLLTLKDYTPQEIRYILDIAKQVKAERKAGVVHQRFLGKTIALIFEKRSTRTRCAFETAFGEEGGHPVFLSTD
DIQLGAKESIEDTARVLGRMFDAIEFRGFKQETVEILAKYAGVPVYNGLTDEYHPTQVLADLMTIEEEFGNLKGRKLVFV
GDGRNNMANTLAVGCAKMGMHYVINSPKELWPSQEFIDEIRQMAAENGGTFELTSVPGEGLEGADAIYTDVWASMGEEAK
ATEREALLRPFQVNEEMMKKTGREDTIFLHCLPAVKGQEVTFDVIEGKQSRVWDQAENRKHTIKAVMIATLL

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=311, Percent_Identity=44.6945337620579, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI18105007, Length=322, Percent_Identity=26.3975155279503, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1790703, Length=329, Percent_Identity=48.936170212766, Blast_Score=309, Evalue=1e-85,
Organism=Escherichia coli, GI1786469, Length=333, Percent_Identity=48.6486486486487, Blast_Score=302, Evalue=2e-83,
Organism=Escherichia coli, GI48994908, Length=359, Percent_Identity=25.3481894150418, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI2367364, Length=307, Percent_Identity=28.3387622149837, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193204318, Length=233, Percent_Identity=29.6137339055794, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322373, Length=308, Percent_Identity=36.3636363636364, Blast_Score=194, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6322331, Length=287, Percent_Identity=28.2229965156794, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24642586, Length=309, Percent_Identity=27.5080906148867, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 35106; Mature: 34974

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFNLKGRSLLTLKDYTPQEIRYILDIAKQVKAERKAGVVHQRFLGKTIALIFEKRSTRT
CEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
RCAFETAFGEEGGHPVFLSTDDIQLGAKESIEDTARVLGRMFDAIEFRGFKQETVEILAK
HHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
YAGVPVYNGLTDEYHPTQVLADLMTIEEEFGNLKGRKLVFVGDGRNNMANTLAVGCAKMG
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHC
MHYVINSPKELWPSQEFIDEIRQMAAENGGTFELTSVPGEGLEGADAIYTDVWASMGEEA
HHHEECCHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCHH
KATEREALLRPFQVNEEMMKKTGREDTIFLHCLPAVKGQEVTFDVIEGKQSRVWDQAENR
HHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEEECCCCCCCEEEHHHCCCHHHHHHHHHCH
KHTIKAVMIATLL
HHHHHHHHHHHCC
>Mature Secondary Structure 
AFNLKGRSLLTLKDYTPQEIRYILDIAKQVKAERKAGVVHQRFLGKTIALIFEKRSTRT
EECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
RCAFETAFGEEGGHPVFLSTDDIQLGAKESIEDTARVLGRMFDAIEFRGFKQETVEILAK
HHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
YAGVPVYNGLTDEYHPTQVLADLMTIEEEFGNLKGRKLVFVGDGRNNMANTLAVGCAKMG
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHC
MHYVINSPKELWPSQEFIDEIRQMAAENGGTFELTSVPGEGLEGADAIYTDVWASMGEEA
HHHEECCHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCHH
KATEREALLRPFQVNEEMMKKTGREDTIFLHCLPAVKGQEVTFDVIEGKQSRVWDQAENR
HHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEEECCCCCCCEEEHHHCCCHHHHHHHHHCH
KHTIKAVMIATLL
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]