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The map label for this gene is yesM [H]

Identifier: 167039061

GI number: 167039061

Start: 407852

End: 409555

Strand: Direct

Name: yesM [H]

Synonym: Teth514_0398

Alternate gene names: 167039061

Gene position: 407852-409555 (Clockwise)

Preceding gene: 167039056

Following gene: 167039062

Centisome position: 16.6

GC content: 29.75

Gene sequence:

>1704_bases
ATGTTATACAAAAAAATTTTGCTTTCATACATTTTAATAATAGTTATACCGCTCATAATGGTGGCGGCGATAACAGGCAA
TATTACATCAAGATATATAAATGAAGAGGTAAAAAAGACTACTTTTCAGACCCTAAATCAAGCAAATAAAAATATATCAA
AAATGCTAGAAAATATGAAAAATGCTATACTATATGTTTCAATGAATAAAGAACTTCAGTATAATTTATCACGCAATGGG
GGAGAAACTCCTTTTCAAATAAACAGAGAAGTTACAGCTATAAGAAACAGTATATTATATCCCGGAATATTTAATGAAAA
TTATTCTTCTATAGAAATTTTTGCTTTGCATAAAAATCAATATCCAATGAGGTTAGAACAAAATGATGTGATGTCTTCAA
AAGTAGTAGAAAATAAAGAATGGTACAAAAAGACTATACAGCTTAATGGCAGGTTGTACTGGTATATAAACGACGATTTT
GGAAAACAAATGATTTCTGTTTCAAGGTTGGTTTTCGATATAAAAAATTTTGCCAAACCTATAGCAGTCATTTCTGTAGA
TATGGACATGTCCAAAGTTGCCTCAGTGGTATCTGATATACACCTTGGGAAAACAGGTAAGGTATATCTAGTTGATGATA
AGGGTAAACTCATATATTCCGAGGACAAAAGCTTTTTATATCGTTATACCACTAAATTATACAATAGCAGTTCTGGAAGT
GATTTTATTACTATAAATGGTAATAAAATAATGGTTATATACAATACTCTACCTCAAAATGGGTGGAAACTTGTTGGTAT
GGTATCTATGGCTGAACTTAATGAAAAAGCTGAGATGATAAGAAATTTTATCTATCTTACTGCGCTTTTGAGTCTTGTAA
TTGCAGCCTTGATTTCTCTTTATTTTTCATACAGTATTTCACAGCCAATAATAAAACTTGCTACTGAAATGAAAAAAGTT
GAAAAAGGTAATTTCAACATAAGTGTTGAAGAAAACTGGGATGGAGAAATAGGAGTATTGTATTCAAGTTTTAACTACAT
GATAGAAAGGATAAATGAACTTATACATGAAGTGTATTTATCAAAAATAAAGGAAAAAGACGCGGAATTAAAAGCTTTGC
AGGCACAGATAAATCCACATTTTTTATACAACACACTTGATACTGTAAATTGGTTGGCAGTAAAACATAATGTACCTGAA
ATAAGCAAGATTGTAAATTCTTTAGCATCAATTTTGAGATACAGCATTAATAAAGGGAATGATGTAACTACTGTTGAAAA
TGAATTGAAGCATGTTGAAAGCTATATTACAATTCAAAAAATCAGATTTAAAGATAAGTTTGAGGTGAGTTTTAATATAG
ATAAAAGAGTTTTACACTACAAGACGATAAAGTTAATTTTGCAGCCTCTTGTTGAAAATGCAATAATTCATGGGATAGAG
ACTTATGAAGGAAAAGGGAAAATTTTGATTAACGGTTATTTAGATGGTGAAAAAATTGTATTCGAGGTCATAAACAATGG
TAATCCTATAGATTTAGATTTAGTAAATAAACTATTGGATTCGCCAGCAGATGATAAAGATAGTTATGGAATACAAAATG
TTAATGAAAGGATTAAGTTATATTATGGGGAAGAGTATGGACTTTATTACCAAGCAATAGATAGCAATACTGTTGCCCGA
ATTGTAATTCCTGCTGTTTTGTGA

Upstream 100 bases:

>100_bases
GTGACATTTTTAATATTTTGTGTATTTTTTTATAAACTTTTAATTATAAAGAAGGTAGTTGCTATATTCTGTTGAAATAT
TTATATAAAAGGTGGTTTTT

Downstream 100 bases:

>100_bases
GGTGGATTTTATGAAAATTTTAATTGTAGATGATGAACCGATTGTAAGAGAAGGGCTTAAAAATAATGTTAGTTGGCAGG
AGTTAGATTTACGTGTGGTA

Product: histidine kinase internal region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MLYKKILLSYILIIVIPLIMVAAITGNITSRYINEEVKKTTFQTLNQANKNISKMLENMKNAILYVSMNKELQYNLSRNG
GETPFQINREVTAIRNSILYPGIFNENYSSIEIFALHKNQYPMRLEQNDVMSSKVVENKEWYKKTIQLNGRLYWYINDDF
GKQMISVSRLVFDIKNFAKPIAVISVDMDMSKVASVVSDIHLGKTGKVYLVDDKGKLIYSEDKSFLYRYTTKLYNSSSGS
DFITINGNKIMVIYNTLPQNGWKLVGMVSMAELNEKAEMIRNFIYLTALLSLVIAALISLYFSYSISQPIIKLATEMKKV
EKGNFNISVEENWDGEIGVLYSSFNYMIERINELIHEVYLSKIKEKDAELKALQAQINPHFLYNTLDTVNWLAVKHNVPE
ISKIVNSLASILRYSINKGNDVTTVENELKHVESYITIQKIRFKDKFEVSFNIDKRVLHYKTIKLILQPLVENAIIHGIE
TYEGKGKILINGYLDGEKIVFEVINNGNPIDLDLVNKLLDSPADDKDSYGIQNVNERIKLYYGEEYGLYYQAIDSNTVAR
IVIPAVL

Sequences:

>Translated_567_residues
MLYKKILLSYILIIVIPLIMVAAITGNITSRYINEEVKKTTFQTLNQANKNISKMLENMKNAILYVSMNKELQYNLSRNG
GETPFQINREVTAIRNSILYPGIFNENYSSIEIFALHKNQYPMRLEQNDVMSSKVVENKEWYKKTIQLNGRLYWYINDDF
GKQMISVSRLVFDIKNFAKPIAVISVDMDMSKVASVVSDIHLGKTGKVYLVDDKGKLIYSEDKSFLYRYTTKLYNSSSGS
DFITINGNKIMVIYNTLPQNGWKLVGMVSMAELNEKAEMIRNFIYLTALLSLVIAALISLYFSYSISQPIIKLATEMKKV
EKGNFNISVEENWDGEIGVLYSSFNYMIERINELIHEVYLSKIKEKDAELKALQAQINPHFLYNTLDTVNWLAVKHNVPE
ISKIVNSLASILRYSINKGNDVTTVENELKHVESYITIQKIRFKDKFEVSFNIDKRVLHYKTIKLILQPLVENAIIHGIE
TYEGKGKILINGYLDGEKIVFEVINNGNPIDLDLVNKLLDSPADDKDSYGIQNVNERIKLYYGEEYGLYYQAIDSNTVAR
IVIPAVL
>Mature_567_residues
MLYKKILLSYILIIVIPLIMVAAITGNITSRYINEEVKKTTFQTLNQANKNISKMLENMKNAILYVSMNKELQYNLSRNG
GETPFQINREVTAIRNSILYPGIFNENYSSIEIFALHKNQYPMRLEQNDVMSSKVVENKEWYKKTIQLNGRLYWYINDDF
GKQMISVSRLVFDIKNFAKPIAVISVDMDMSKVASVVSDIHLGKTGKVYLVDDKGKLIYSEDKSFLYRYTTKLYNSSSGS
DFITINGNKIMVIYNTLPQNGWKLVGMVSMAELNEKAEMIRNFIYLTALLSLVIAALISLYFSYSISQPIIKLATEMKKV
EKGNFNISVEENWDGEIGVLYSSFNYMIERINELIHEVYLSKIKEKDAELKALQAQINPHFLYNTLDTVNWLAVKHNVPE
ISKIVNSLASILRYSINKGNDVTTVENELKHVESYITIQKIRFKDKFEVSFNIDKRVLHYKTIKLILQPLVENAIIHGIE
TYEGKGKILINGYLDGEKIVFEVINNGNPIDLDLVNKLLDSPADDKDSYGIQNVNERIKLYYGEEYGLYYQAIDSNTVAR
IVIPAVL

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=198, Percent_Identity=34.8484848484849, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788446, Length=231, Percent_Identity=27.2727272727273, Blast_Score=113, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65071; Mature: 65071

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYKKILLSYILIIVIPLIMVAAITGNITSRYINEEVKKTTFQTLNQANKNISKMLENMK
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NAILYVSMNKELQYNLSRNGGETPFQINREVTAIRNSILYPGIFNENYSSIEIFALHKNQ
CEEEEEEECCCEEEEECCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCC
YPMRLEQNDVMSSKVVENKEWYKKTIQLNGRLYWYINDDFGKQMISVSRLVFDIKNFAKP
CCCEECCCHHHHHHHHCCHHHHHHHEEECCEEEEEEECHHHHHHHHHHHHHHHHHHHCCC
IAVISVDMDMSKVASVVSDIHLGKTGKVYLVDDKGKLIYSEDKSFLYRYTTKLYNSSSGS
EEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHCCCCCC
DFITINGNKIMVIYNTLPQNGWKLVGMVSMAELNEKAEMIRNFIYLTALLSLVIAALISL
EEEEECCCEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFSYSISQPIIKLATEMKKVEKGNFNISVEENWDGEIGVLYSSFNYMIERINELIHEVYL
HHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
SKIKEKDAELKALQAQINPHFLYNTLDTVNWLAVKHNVPEISKIVNSLASILRYSINKGN
HHHHHCCHHHHHHHHHCCCEEEEEHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
DVTTVENELKHVESYITIQKIRFKDKFEVSFNIDKRVLHYKTIKLILQPLVENAIIHGIE
CCCHHHHHHHHHHHHHHHEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCE
TYEGKGKILINGYLDGEKIVFEVINNGNPIDLDLVNKLLDSPADDKDSYGIQNVNERIKL
EECCCCEEEEEEEECCCEEEEEEECCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCEEEE
YYGEEYGLYYQAIDSNTVARIVIPAVL
EECCCCCEEEEEECCCCEEEEEEECCC
>Mature Secondary Structure
MLYKKILLSYILIIVIPLIMVAAITGNITSRYINEEVKKTTFQTLNQANKNISKMLENMK
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NAILYVSMNKELQYNLSRNGGETPFQINREVTAIRNSILYPGIFNENYSSIEIFALHKNQ
CEEEEEEECCCEEEEECCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCCEEEEEEEECCC
YPMRLEQNDVMSSKVVENKEWYKKTIQLNGRLYWYINDDFGKQMISVSRLVFDIKNFAKP
CCCEECCCHHHHHHHHCCHHHHHHHEEECCEEEEEEECHHHHHHHHHHHHHHHHHHHCCC
IAVISVDMDMSKVASVVSDIHLGKTGKVYLVDDKGKLIYSEDKSFLYRYTTKLYNSSSGS
EEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHCCCCCC
DFITINGNKIMVIYNTLPQNGWKLVGMVSMAELNEKAEMIRNFIYLTALLSLVIAALISL
EEEEECCCEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFSYSISQPIIKLATEMKKVEKGNFNISVEENWDGEIGVLYSSFNYMIERINELIHEVYL
HHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
SKIKEKDAELKALQAQINPHFLYNTLDTVNWLAVKHNVPEISKIVNSLASILRYSINKGN
HHHHHCCHHHHHHHHHCCCEEEEEHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
DVTTVENELKHVESYITIQKIRFKDKFEVSFNIDKRVLHYKTIKLILQPLVENAIIHGIE
CCCHHHHHHHHHHHHHHHEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCE
TYEGKGKILINGYLDGEKIVFEVINNGNPIDLDLVNKLLDSPADDKDSYGIQNVNERIKL
EECCCCEEEEEEEECCCEEEEEEECCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCEEEE
YYGEEYGLYYQAIDSNTVARIVIPAVL
EECCCCCEEEEEECCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]