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The map label for this gene is ahpC [C]

Identifier: 167038876

GI number: 167038876

Start: 218284

End: 218931

Strand: Reverse

Name: ahpC [C]

Synonym: Teth514_0207

Alternate gene names: 167038876

Gene position: 218931-218284 (Counterclockwise)

Preceding gene: 167038877

Following gene: 167038875

Centisome position: 8.91

GC content: 36.27

Gene sequence:

>648_bases
ATGAAATTGTTAGGAGAAAAATTCCCATCTATGGAGGTAGTAACAACTCAAGGAGTAAAGAGACTGCCTGAGGATTACGC
GGGAAAGTGGTTTGTGCTTTTTAGCCACCCAGCAGACTTTACACCAGTTTGCACAACAGAATTTGTAGAATTTGCAAGGA
AAGCTAATGACTTTAAAGAATTAAACACTGAATTAATAGGTCTATCAGTTGACCAAGTTTTCTCCCACATAAAATGGGTA
GAGTGGATAAAGGACAACACAAACATAGCTATTCCTTTCCCAGTAATAGCTGATGACTTAGGAAAAGTCTCTAACCAATT
AGGAATGATTCATCCAGGCAAAGGTACCAATACTGTAAGAGCAGTATTTATAGTAGACGACAAAGGAACAATAAGACTTA
TAATGTATTATCCACAAGAAGTTGGAAGAAATGTAGATGAAATATTAAGAGCATTAAAAGCATTGCAAACAGCAGACCAA
TACGGCGTGGCACTCCCTGAAAAATGGCCAAATAACTACTTAATTAAAGACCATGTAATAGTCCCACCATCCACTGATGA
AGCTTCTGCAAATGAAAGAAAAGAAAAAATTAAATCAAAAGAAATTGAAGCTTTTGACTGGTGGTTTGTACACAAGCCTT
TGAAATAA

Upstream 100 bases:

>100_bases
AAAAGGCTTTGTAATTAGAAATGTTGACATAAATGTTTATGGCATATGCAAAAAATGTAATGAGAAAAATAAGGAGGTTT
AAAAAATGGAGGAAATTAGA

Downstream 100 bases:

>100_bases
GGTCACTCATAAAATATCCCTTCTTTTCGACAGCGACGACCTCTTTAACAAAGTAGGTCGTCGCTTTAGTTTGCTGATAA
ATGAAATCTTTATGAGATGT

Product: putative peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKLLGEKFPSMEVVTTQGVKRLPEDYAGKWFVLFSHPADFTPVCTTEFVEFARKANDFKELNTELIGLSVDQVFSHIKWV
EWIKDNTNIAIPFPVIADDLGKVSNQLGMIHPGKGTNTVRAVFIVDDKGTIRLIMYYPQEVGRNVDEILRALKALQTADQ
YGVALPEKWPNNYLIKDHVIVPPSTDEASANERKEKIKSKEIEAFDWWFVHKPLK

Sequences:

>Translated_215_residues
MKLLGEKFPSMEVVTTQGVKRLPEDYAGKWFVLFSHPADFTPVCTTEFVEFARKANDFKELNTELIGLSVDQVFSHIKWV
EWIKDNTNIAIPFPVIADDLGKVSNQLGMIHPGKGTNTVRAVFIVDDKGTIRLIMYYPQEVGRNVDEILRALKALQTADQ
YGVALPEKWPNNYLIKDHVIVPPSTDEASANERKEKIKSKEIEAFDWWFVHKPLK
>Mature_215_residues
MKLLGEKFPSMEVVTTQGVKRLPEDYAGKWFVLFSHPADFTPVCTTEFVEFARKANDFKELNTELIGLSVDQVFSHIKWV
EWIKDNTNIAIPFPVIADDLGKVSNQLGMIHPGKGTNTVRAVFIVDDKGTIRLIMYYPQEVGRNVDEILRALKALQTADQ
YGVALPEKWPNNYLIKDHVIVPPSTDEASANERKEKIKSKEIEAFDWWFVHKPLK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=221, Percent_Identity=35.7466063348416, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI32189392, Length=158, Percent_Identity=37.9746835443038, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI4505591, Length=158, Percent_Identity=38.6075949367089, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI32455266, Length=158, Percent_Identity=38.6075949367089, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI32455264, Length=158, Percent_Identity=38.6075949367089, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI5453549, Length=146, Percent_Identity=37.6712328767123, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI5802974, Length=155, Percent_Identity=36.7741935483871, Blast_Score=110, Evalue=8e-25,
Organism=Homo sapiens, GI32483377, Length=155, Percent_Identity=36.7741935483871, Blast_Score=110, Evalue=9e-25,
Organism=Homo sapiens, GI33188454, Length=58, Percent_Identity=50, Blast_Score=71, Evalue=7e-13,
Organism=Escherichia coli, GI1786822, Length=147, Percent_Identity=31.9727891156463, Blast_Score=80, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17554494, Length=147, Percent_Identity=37.4149659863946, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI193204376, Length=175, Percent_Identity=35.4285714285714, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32565831, Length=175, Percent_Identity=35.4285714285714, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25153706, Length=195, Percent_Identity=32.3076923076923, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319407, Length=192, Percent_Identity=43.2291666666667, Blast_Score=137, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6323613, Length=158, Percent_Identity=35.4430379746835, Blast_Score=89, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320661, Length=158, Percent_Identity=33.5443037974684, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI17975518, Length=196, Percent_Identity=40.3061224489796, Blast_Score=130, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24652434, Length=196, Percent_Identity=40.3061224489796, Blast_Score=130, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24652436, Length=196, Percent_Identity=39.7959183673469, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24581278, Length=172, Percent_Identity=38.953488372093, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17738015, Length=151, Percent_Identity=39.0728476821192, Blast_Score=116, Evalue=9e-27,
Organism=Drosophila melanogaster, GI17157991, Length=147, Percent_Identity=38.0952380952381, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24641739, Length=147, Percent_Identity=38.0952380952381, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24656348, Length=164, Percent_Identity=34.7560975609756, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17864676, Length=164, Percent_Identity=34.7560975609756, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21357347, Length=146, Percent_Identity=34.2465753424658, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24560; Mature: 24560

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLGEKFPSMEVVTTQGVKRLPEDYAGKWFVLFSHPADFTPVCTTEFVEFARKANDFKE
CCCCCCCCCCEEEEEHHHHHHCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCHHHH
LNTELIGLSVDQVFSHIKWVEWIKDNTNIAIPFPVIADDLGKVSNQLGMIHPGKGTNTVR
HCHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCEECCCCCCEEE
AVFIVDDKGTIRLIMYYPQEVGRNVDEILRALKALQTADQYGVALPEKWPNNYLIKDHVI
EEEEEECCCCEEEEEECCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCEE
VPPSTDEASANERKEKIKSKEIEAFDWWFVHKPLK
ECCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCC
>Mature Secondary Structure
MKLLGEKFPSMEVVTTQGVKRLPEDYAGKWFVLFSHPADFTPVCTTEFVEFARKANDFKE
CCCCCCCCCCEEEEEHHHHHHCCHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCHHHH
LNTELIGLSVDQVFSHIKWVEWIKDNTNIAIPFPVIADDLGKVSNQLGMIHPGKGTNTVR
HCHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCEECCCCCCEEE
AVFIVDDKGTIRLIMYYPQEVGRNVDEILRALKALQTADQYGVALPEKWPNNYLIKDHVI
EEEEEECCCCEEEEEECCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCEE
VPPSTDEASANERKEKIKSKEIEAFDWWFVHKPLK
ECCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]