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The map label for this gene is eda [H]

Identifier: 167038810

GI number: 167038810

Start: 134353

End: 134985

Strand: Direct

Name: eda [H]

Synonym: Teth514_0137

Alternate gene names: 167038810

Gene position: 134353-134985 (Clockwise)

Preceding gene: 167038809

Following gene: 167038811

Centisome position: 5.47

GC content: 32.86

Gene sequence:

>633_bases
ATGGAAAAACAACAAATAATTGAAAAACTTAAACAACTTAAAATTACAGCTGTAATTAGAAATAGTGATATAAACACAAT
GTTTTCTTTAGCTGATGCCTTAAAAAAAGGTGGTATTGAAGCATTAGAAATAACTGTTGAAGCGCCCGGTGCTATAGATG
TAATCAAAGAATTAAGTAAAGCAAATAAATATTTTGTTGGTGCTGGAACAGTATTAGATGCGGAAACTGCGAGGGCTGCT
ATTATAGCAGGTGCAAAATTTATATTTACACCGGTTATGAGACTTGATGTAATAAAATTATGTAATAGGTATGGTATACC
TGTTATTCCTGGTGCTACTACTCCGACAGAAATTTTAACAGGTTATGAAGCAGGAGCGGATTTTATTAAAGTTTTTCCTG
CAGGAGTTTTTGGACCTCAATATTTAAAAGAAATTTTAGGGCCACTCAAACATATACCCATTTTTGTGACGGGAGGAATT
AATAAAAATAATATTAAAGATTTTATTTTAGCAGGTGCAACAGGCGTATCCTTAGGCGGAGCATTAGTAGATAAAGAACT
TATTGCAAAAGGCATGTTTGACAAAATAACCGAAAAAGCTATTGAGTTTGTAAGGCTGGTAAATCAAGTTTAG

Upstream 100 bases:

>100_bases
TGGCAGTGGAAGGACTTATCAGCGTATTAGAAGGCATGGAACCAAAATATCTTTATAAAAGGCAGAAATAAAATAATTTT
AAAAAATAGGAGGTAGGAAG

Downstream 100 bases:

>100_bases
TTTACATGAAAGGGCATTGATTCAGCAGCAGGTTTAGCCTTATCAGGACTTAAGGAACCATCATAAAATTTAATATGACA
GACAATACGTAATTCATTAG

Product: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase; 2-keto-4-hydroxyglutarate aldolase; KHG-aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MEKQQIIEKLKQLKITAVIRNSDINTMFSLADALKKGGIEALEITVEAPGAIDVIKELSKANKYFVGAGTVLDAETARAA
IIAGAKFIFTPVMRLDVIKLCNRYGIPVIPGATTPTEILTGYEAGADFIKVFPAGVFGPQYLKEILGPLKHIPIFVTGGI
NKNNIKDFILAGATGVSLGGALVDKELIAKGMFDKITEKAIEFVRLVNQV

Sequences:

>Translated_210_residues
MEKQQIIEKLKQLKITAVIRNSDINTMFSLADALKKGGIEALEITVEAPGAIDVIKELSKANKYFVGAGTVLDAETARAA
IIAGAKFIFTPVMRLDVIKLCNRYGIPVIPGATTPTEILTGYEAGADFIKVFPAGVFGPQYLKEILGPLKHIPIFVTGGI
NKNNIKDFILAGATGVSLGGALVDKELIAKGMFDKITEKAIEFVRLVNQV
>Mature_210_residues
MEKQQIIEKLKQLKITAVIRNSDINTMFSLADALKKGGIEALEITVEAPGAIDVIKELSKANKYFVGAGTVLDAETARAA
IIAGAKFIFTPVMRLDVIKLCNRYGIPVIPGATTPTEILTGYEAGADFIKVFPAGVFGPQYLKEILGPLKHIPIFVTGGI
NKNNIKDFILAGATGVSLGGALVDKELIAKGMFDKITEKAIEFVRLVNQV

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI48994954, Length=202, Percent_Identity=32.1782178217822, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788156, Length=179, Percent_Identity=34.6368715083799, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.3.16; =4.1.2.14 [H]

Molecular weight: Translated: 22545; Mature: 22545

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQQIIEKLKQLKITAVIRNSDINTMFSLADALKKGGIEALEITVEAPGAIDVIKELSK
CCHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHH
ANKYFVGAGTVLDAETARAAIIAGAKFIFTPVMRLDVIKLCNRYGIPVIPGATTPTEILT
CCCEEEECCCEECHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
GYEAGADFIKVFPAGVFGPQYLKEILGPLKHIPIFVTGGINKNNIKDFILAGATGVSLGG
CHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHCCCCCHHHCH
ALVDKELIAKGMFDKITEKAIEFVRLVNQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKQQIIEKLKQLKITAVIRNSDINTMFSLADALKKGGIEALEITVEAPGAIDVIKELSK
CCHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHH
ANKYFVGAGTVLDAETARAAIIAGAKFIFTPVMRLDVIKLCNRYGIPVIPGATTPTEILT
CCCEEEECCCEECHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
GYEAGADFIKVFPAGVFGPQYLKEILGPLKHIPIFVTGGINKNNIKDFILAGATGVSLGG
CHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHCCCCCHHHCH
ALVDKELIAKGMFDKITEKAIEFVRLVNQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]