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The map label for this gene is dgoA [H]

Identifier: 167038802

GI number: 167038802

Start: 125375

End: 126022

Strand: Direct

Name: dgoA [H]

Synonym: Teth514_0129

Alternate gene names: 167038802

Gene position: 125375-126022 (Clockwise)

Preceding gene: 167038801

Following gene: 167038803

Centisome position: 5.1

GC content: 36.27

Gene sequence:

>648_bases
ATGAAAAGCTATGAGGTATTAAATAAGATTAAGGAAGTAGGAATTTGTGCAATTGTAAGGGGTACATCCGTTGATTCATT
ATATAGAATTGCAGATTCACTGATTGCAGGGGGAATAAAAGCTATTGAAGTTGCATTTAATACCCCTGGTGCTGCTAAGA
TGATAGAAAAACTTGTTGAAAAATATAGTGATCAGGTATTAGTAGGTGCAGGTACTGTCTTAGATGCTGAAACTGCGAGA
ATTGCTATACTGTCAGGAGCATCATTTATATTATCACCTTCTTTAAATCTAGAAATGATAAAAATATGCCAAAGGTACAA
TGTACTACCTGTTCCGGGCATTTCGACACCTACAGAAGCAGTAACAGCGTGGGAAAATGGAGCGCAGATTGTTAAAGTGT
TTCCTGCTGGAGTCTTTGGGCCAAACTATATAAAACAGTTAAAAGGACCTTTATCGCAAATAGAAATGATGGCAGTTGGG
GCAGTAAATCTTGACAATTTTAAAGATTTTATAAAAGCTGGAGCATGTTCTGTAGGAATAGGCAGTGAGCTTGTAAATAA
TAAGCTTGTCGAGGAAGGAAAGTTTGATGAAATAACAAAGAGAGCTGCAGCATTCGTAAATGCGTTTAAAGAAGTTAATG
GTAAATAA

Upstream 100 bases:

>100_bases
AATATGGGAATTGTGGCTGCAAAAAATGTTGTACTAGTGTTAAATAAAAAGCAAGGCGCACACATAGTTAATGGCGAATA
ATTTTTAGGAGGGAATGATT

Downstream 100 bases:

>100_bases
CCAAATTTGTTTTTCCTCCCCTGTTTCTGTATAATTAATGTGCAGGATAAACAAGACAGGGGAGGATATTTTGTTGAGAA
AAAACGCGTATACAATTGCA

Product: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase

Products: NA

Alternate protein names: 2-oxo-3-deoxygalactonate 6-phosphate aldolase; 6-phospho-2-dehydro-3-deoxygalactonate aldolase [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKSYEVLNKIKEVGICAIVRGTSVDSLYRIADSLIAGGIKAIEVAFNTPGAAKMIEKLVEKYSDQVLVGAGTVLDAETAR
IAILSGASFILSPSLNLEMIKICQRYNVLPVPGISTPTEAVTAWENGAQIVKVFPAGVFGPNYIKQLKGPLSQIEMMAVG
AVNLDNFKDFIKAGACSVGIGSELVNNKLVEEGKFDEITKRAAAFVNAFKEVNGK

Sequences:

>Translated_215_residues
MKSYEVLNKIKEVGICAIVRGTSVDSLYRIADSLIAGGIKAIEVAFNTPGAAKMIEKLVEKYSDQVLVGAGTVLDAETAR
IAILSGASFILSPSLNLEMIKICQRYNVLPVPGISTPTEAVTAWENGAQIVKVFPAGVFGPNYIKQLKGPLSQIEMMAVG
AVNLDNFKDFIKAGACSVGIGSELVNNKLVEEGKFDEITKRAAAFVNAFKEVNGK
>Mature_215_residues
MKSYEVLNKIKEVGICAIVRGTSVDSLYRIADSLIAGGIKAIEVAFNTPGAAKMIEKLVEKYSDQVLVGAGTVLDAETAR
IAILSGASFILSPSLNLEMIKICQRYNVLPVPGISTPTEAVTAWENGAQIVKVFPAGVFGPNYIKQLKGPLSQIEMMAVG
AVNLDNFKDFIKAGACSVGIGSELVNNKLVEEGKFDEITKRAAAFVNAFKEVNGK

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI48994954, Length=196, Percent_Identity=37.7551020408163, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1788156, Length=182, Percent_Identity=31.3186813186813, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.2.21 [H]

Molecular weight: Translated: 22913; Mature: 22913

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSYEVLNKIKEVGICAIVRGTSVDSLYRIADSLIAGGIKAIEVAFNTPGAAKMIEKLVE
CCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHH
KYSDQVLVGAGTVLDAETARIAILSGASFILSPSLNLEMIKICQRYNVLPVPGISTPTEA
HHCCCEEEECCCEEECCCCEEEEEECCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHH
VTAWENGAQIVKVFPAGVFGPNYIKQLKGPLSQIEMMAVGAVNLDNFKDFIKAGACSVGI
HHHHCCCCEEEEECCCCCCCHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
GSELVNNKLVEEGKFDEITKRAAAFVNAFKEVNGK
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSYEVLNKIKEVGICAIVRGTSVDSLYRIADSLIAGGIKAIEVAFNTPGAAKMIEKLVE
CCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHH
KYSDQVLVGAGTVLDAETARIAILSGASFILSPSLNLEMIKICQRYNVLPVPGISTPTEA
HHCCCEEEECCCEEECCCCEEEEEECCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHH
VTAWENGAQIVKVFPAGVFGPNYIKQLKGPLSQIEMMAVGAVNLDNFKDFIKAGACSVGI
HHHHCCCCEEEEECCCCCCCHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
GSELVNNKLVEEGKFDEITKRAAAFVNAFKEVNGK
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]