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The map label for this gene is dgoD [H]

Identifier: 167038800

GI number: 167038800

Start: 123159

End: 124304

Strand: Direct

Name: dgoD [H]

Synonym: Teth514_0127

Alternate gene names: 167038800

Gene position: 123159-124304 (Clockwise)

Preceding gene: 167038799

Following gene: 167038801

Centisome position: 5.01

GC content: 36.21

Gene sequence:

>1146_bases
ATGAAGATTACATCATTAAAGGTATATAAGGTAAAACCAAGATGGATATTTTTAAAGATAGATACAGATGAAGGGATTAG
TGGATGGGGTGAATTGATTTCGGGTACTAAAACAGAAACAGTTGTTGCAGGCGCATATGAAATGGGAGAGTATCTTATTG
ATAAAGACCCGAGACAAATTGAGGATATGTGGCAAGTAATATATAGGTCCTTTTTTAGAGGCGGTCCTATAAATATGACA
ATTTTATCAGGCATAGAAATGGCATTATGGGACATAAAAGGCAAATATTATAATATGCCAGTATATGAATTTTTGGGCGG
AAAAGCAAGAGACAAAATAATGGTTTACTCATGGATTGGTGGAGATAGACCCTCAGATGTAGTGGAAGCAGCTTTGGATA
GGAAGAATAAAGGTTTCAAGGCAATAAAAATGAACGCCACAGAGGAACTTCATTATATTGATTCATATAAAAAAATTGAA
GCTGTTATTGAAAGAGTGGCATCAATAAGAGATGCTGTTGGTTATGAAATGGAGATAGGGATAGATTTCCACGGACGTGT
TCATAAGGCAATGGCTAAAGTTTTAGCTAAAGAATTGGAAAAATACAGGCCGATGTTTATAGAAGAACCTGTATTACCCG
AAAACAATGAAGCACTGAAGGAAATAGCAAGTTATACATCCATACCTATTGCGACAGGTGAAAGATTATATACTAGGTGG
GGATTCAAAGATGTATTAAAAAGCGGTGTTGTAGATATAATTCAACCCGATGTAGCATTAACAGGGGGTATTCTTGAAGC
TAAAAAAATATCTGCTATGGCAGAAGCGTTTGATGTAGCTGTAGCTCCACATGCTCCGTATGGTCCAATTGCACTTGCTG
CTACATTACAATTAGATATCTGTACACCTAATGTGTTTATACAAGAACAAAGCTTAGGCATACACTATAATCAAGGTTTT
GATTTACTTGATTTTGTAAAGAATAAAGAAATCTTTGCGTATAAGGATGGCTTTGTCGATATTCCAACGGGCCCAGGACT
TGGTATTGAAATCGATGAAGAATTAGTCAAAAAAGTTGATATGGAAGGATTACATTGGACTAACCCAAAGTGGAGGAATT
ACGATGGAACGGTAGCTGAGTGGTAA

Upstream 100 bases:

>100_bases
TCGTGGTAAGGTAATAAAACATTCCTTAGATTATAAGAAGCTGAGAGTAAAAAAGGTTCAACACAAGTAAGACATTAAAA
TGAGGAGGGGAGAAATAAAG

Downstream 100 bases:

>100_bases
TATTATTAAGCAGTAAATAACGCATATATCGGATAATTAAAAAGCAATTTAAACAGTAAATAACATTGGATTTTCAAGGG
GTGATACAATGTCTAAGTAT

Product: galactonate dehydratase

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKITSLKVYKVKPRWIFLKIDTDEGISGWGELISGTKTETVVAGAYEMGEYLIDKDPRQIEDMWQVIYRSFFRGGPINMT
ILSGIEMALWDIKGKYYNMPVYEFLGGKARDKIMVYSWIGGDRPSDVVEAALDRKNKGFKAIKMNATEELHYIDSYKKIE
AVIERVASIRDAVGYEMEIGIDFHGRVHKAMAKVLAKELEKYRPMFIEEPVLPENNEALKEIASYTSIPIATGERLYTRW
GFKDVLKSGVVDIIQPDVALTGGILEAKKISAMAEAFDVAVAPHAPYGPIALAATLQLDICTPNVFIQEQSLGIHYNQGF
DLLDFVKNKEIFAYKDGFVDIPTGPGLGIEIDEELVKKVDMEGLHWTNPKWRNYDGTVAEW

Sequences:

>Translated_381_residues
MKITSLKVYKVKPRWIFLKIDTDEGISGWGELISGTKTETVVAGAYEMGEYLIDKDPRQIEDMWQVIYRSFFRGGPINMT
ILSGIEMALWDIKGKYYNMPVYEFLGGKARDKIMVYSWIGGDRPSDVVEAALDRKNKGFKAIKMNATEELHYIDSYKKIE
AVIERVASIRDAVGYEMEIGIDFHGRVHKAMAKVLAKELEKYRPMFIEEPVLPENNEALKEIASYTSIPIATGERLYTRW
GFKDVLKSGVVDIIQPDVALTGGILEAKKISAMAEAFDVAVAPHAPYGPIALAATLQLDICTPNVFIQEQSLGIHYNQGF
DLLDFVKNKEIFAYKDGFVDIPTGPGLGIEIDEELVKKVDMEGLHWTNPKWRNYDGTVAEW
>Mature_381_residues
MKITSLKVYKVKPRWIFLKIDTDEGISGWGELISGTKTETVVAGAYEMGEYLIDKDPRQIEDMWQVIYRSFFRGGPINMT
ILSGIEMALWDIKGKYYNMPVYEFLGGKARDKIMVYSWIGGDRPSDVVEAALDRKNKGFKAIKMNATEELHYIDSYKKIE
AVIERVASIRDAVGYEMEIGIDFHGRVHKAMAKVLAKELEKYRPMFIEEPVLPENNEALKEIASYTSIPIATGERLYTRW
GFKDVLKSGVVDIIQPDVALTGGILEAKKISAMAEAFDVAVAPHAPYGPIALAATLQLDICTPNVFIQEQSLGIHYNQGF
DLLDFVKNKEIFAYKDGFVDIPTGPGLGIEIDEELVKKVDMEGLHWTNPKWRNYDGTVAEW

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=394, Percent_Identity=23.8578680203046, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI186972148, Length=199, Percent_Identity=27.6381909547739, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI48994953, Length=382, Percent_Identity=53.4031413612565, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1787864, Length=415, Percent_Identity=28.6746987951807, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI226510960, Length=263, Percent_Identity=28.5171102661597, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 43024; Mature: 43024

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITSLKVYKVKPRWIFLKIDTDEGISGWGELISGTKTETVVAGAYEMGEYLIDKDPRQI
CCCEEEEEEEECCEEEEEEEECCCCCCHHHHHHCCCCCCEEEECHHHHHHHHHCCCHHHH
EDMWQVIYRSFFRGGPINMTILSGIEMALWDIKGKYYNMPVYEFLGGKARDKIMVYSWIG
HHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCEECCCHHHHHCCCCCCCEEEEEECC
GDRPSDVVEAALDRKNKGFKAIKMNATEELHYIDSYKKIEAVIERVASIRDAVGYEMEIG
CCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
IDFHGRVHKAMAKVLAKELEKYRPMFIEEPVLPENNEALKEIASYTSIPIATGERLYTRW
EECCCHHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHC
GFKDVLKSGVVDIIQPDVALTGGILEAKKISAMAEAFDVAVAPHAPYGPIALAATLQLDI
CHHHHHHCCCHHHHCCCHHHCCCCHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEEEEEE
CTPNVFIQEQSLGIHYNQGFDLLDFVKNKEIFAYKDGFVDIPTGPGLGIEIDEELVKKVD
ECCCEEEEECCCCEEECCCCCHHHHHCCCCEEEEECCEEECCCCCCCCEEECHHHHHHHC
MEGLHWTNPKWRNYDGTVAEW
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKITSLKVYKVKPRWIFLKIDTDEGISGWGELISGTKTETVVAGAYEMGEYLIDKDPRQI
CCCEEEEEEEECCEEEEEEEECCCCCCHHHHHHCCCCCCEEEECHHHHHHHHHCCCHHHH
EDMWQVIYRSFFRGGPINMTILSGIEMALWDIKGKYYNMPVYEFLGGKARDKIMVYSWIG
HHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCEECCCHHHHHCCCCCCCEEEEEECC
GDRPSDVVEAALDRKNKGFKAIKMNATEELHYIDSYKKIEAVIERVASIRDAVGYEMEIG
CCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
IDFHGRVHKAMAKVLAKELEKYRPMFIEEPVLPENNEALKEIASYTSIPIATGERLYTRW
EECCCHHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHC
GFKDVLKSGVVDIIQPDVALTGGILEAKKISAMAEAFDVAVAPHAPYGPIALAATLQLDI
CHHHHHHCCCHHHHCCCHHHCCCCHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEEEEEE
CTPNVFIQEQSLGIHYNQGFDLLDFVKNKEIFAYKDGFVDIPTGPGLGIEIDEELVKKVD
ECCCEEEEECCCCEEECCCCCHHHHHCCCCEEEEECCEEECCCCCCCCEEECHHHHHHHC
MEGLHWTNPKWRNYDGTVAEW
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA