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The map label for this gene is glcK [H]

Identifier: 167038723

GI number: 167038723

Start: 53601

End: 54548

Strand: Direct

Name: glcK [H]

Synonym: Teth514_0049

Alternate gene names: 167038723

Gene position: 53601-54548 (Clockwise)

Preceding gene: 167038722

Following gene: 167038724

Centisome position: 2.18

GC content: 38.82

Gene sequence:

>948_bases
ATGGGGAGAATCCTATGCGGTGTTGACTTAGGAGGGACAAAGATAAGCACAGGACTCGTGGATGAGAAGGGCAATATCAT
AAGAAGCACAAAAATACCTACTATGGCTGAAAAAGGGCCAGAAGAAGTGATTAAGCGAATAGAACAAAGTGTTTATGACG
TTTTAAAAGAAGCAGGATTAAAATTATCTGATTTAAAAGGAGTTGGGATTGGATCTCCAGGGCCCCTTGATGCCAAAAGG
GGGGTAGTTATAAGCCCACCTAATCTTCCGGGTTGGGACAATGTCCCTATTGTGGATATTTTATCTCATAAGCTGGGAGT
TAAAGTAAAATTAGAGAATGATGCAAATGCTGCAGCTATTGGAGAACATTTATTTGGCGCAGGAAAAGGTATAGACAATT
TTGTTTATATAACTGTAAGTACTGGGATTGGCGGTGGCGTGATAATAGAAGGGAAACTTTATAGCGGAGAAAATTCTAAT
GCAGCTGAGATTGGGCACCATACTATAAATTTTAATGGACCTCGGTGTAATTGCGGAAATTATGGATGTTTTGAGGCTTT
TGCTTCTGGTACAGCTATTGCGAGATTTGCTCAAGAGGGAATTCAAAATGGGAAAGATACAATGATAAGGGATTTAGCTA
AGGATGGAGTAGTAAAATCAGAACATGTATTTGAAGCGGCAAAATTGGGAGATGAGTTTGCGAAAGAATTGGTTGACAAT
GAAGCTTTTTATCTTGGAGTGGGAATTTCAAATATCATGGCTTTTTATAATCCAAAAAAAATTGCCATAGGTGGTGGCGT
ATCCACTCAATGGGATATGCTTTATGATAAAATGATGGAAACAATAAAGAAAAAAGCATTGAAGCCTAATGCCGAGGTTT
GTGAGGTAGTAAGAGCTGAATTAGGAGAAAACGTGGGAGTTTTAGGAGCGGCAGCATTACTCTTATAA

Upstream 100 bases:

>100_bases
CAGTCTGAAATGCCCTTTTGGGCATTTCTTTATTATATTGACTTTAATAGCAAAATGGAGGATACTATATTTAAAAACAG
TGAAGAATGGAGGGATAAAA

Downstream 100 bases:

>100_bases
GAGGTGAAATATGAATAGGTGTCCTTGGTGTCTTAGTGACGAGCTTTACATAAAATATCATGATGAAGAATGGGGAGTGC
CTGTTCATGATGATACAAAG

Product: ROK family glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MGRILCGVDLGGTKISTGLVDEKGNIIRSTKIPTMAEKGPEEVIKRIEQSVYDVLKEAGLKLSDLKGVGIGSPGPLDAKR
GVVISPPNLPGWDNVPIVDILSHKLGVKVKLENDANAAAIGEHLFGAGKGIDNFVYITVSTGIGGGVIIEGKLYSGENSN
AAEIGHHTINFNGPRCNCGNYGCFEAFASGTAIARFAQEGIQNGKDTMIRDLAKDGVVKSEHVFEAAKLGDEFAKELVDN
EAFYLGVGISNIMAFYNPKKIAIGGGVSTQWDMLYDKMMETIKKKALKPNAEVCEVVRAELGENVGVLGAAALLL

Sequences:

>Translated_315_residues
MGRILCGVDLGGTKISTGLVDEKGNIIRSTKIPTMAEKGPEEVIKRIEQSVYDVLKEAGLKLSDLKGVGIGSPGPLDAKR
GVVISPPNLPGWDNVPIVDILSHKLGVKVKLENDANAAAIGEHLFGAGKGIDNFVYITVSTGIGGGVIIEGKLYSGENSN
AAEIGHHTINFNGPRCNCGNYGCFEAFASGTAIARFAQEGIQNGKDTMIRDLAKDGVVKSEHVFEAAKLGDEFAKELVDN
EAFYLGVGISNIMAFYNPKKIAIGGGVSTQWDMLYDKMMETIKKKALKPNAEVCEVVRAELGENVGVLGAAALLL
>Mature_314_residues
GRILCGVDLGGTKISTGLVDEKGNIIRSTKIPTMAEKGPEEVIKRIEQSVYDVLKEAGLKLSDLKGVGIGSPGPLDAKRG
VVISPPNLPGWDNVPIVDILSHKLGVKVKLENDANAAAIGEHLFGAGKGIDNFVYITVSTGIGGGVIIEGKLYSGENSNA
AEIGHHTINFNGPRCNCGNYGCFEAFASGTAIARFAQEGIQNGKDTMIRDLAKDGVVKSEHVFEAAKLGDEFAKELVDNE
AFYLGVGISNIMAFYNPKKIAIGGGVSTQWDMLYDKMMETIKKKALKPNAEVCEVVRAELGENVGVLGAAALLL

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=285, Percent_Identity=34.3859649122807, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI298566325, Length=285, Percent_Identity=34.3859649122807, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI4885285, Length=285, Percent_Identity=34.3859649122807, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI190014632, Length=285, Percent_Identity=34.3859649122807, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI298566312, Length=141, Percent_Identity=31.2056737588652, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1787878, Length=256, Percent_Identity=29.6875, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786891, Length=308, Percent_Identity=27.5974025974026, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1787363, Length=319, Percent_Identity=27.5862068965517, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87081733, Length=316, Percent_Identity=27.8481012658228, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082230, Length=261, Percent_Identity=34.0996168582375, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082127, Length=226, Percent_Identity=25.6637168141593, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790522, Length=314, Percent_Identity=24.5222929936306, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33332; Mature: 33201

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRILCGVDLGGTKISTGLVDEKGNIIRSTKIPTMAEKGPEEVIKRIEQSVYDVLKEAGL
CCEEEEEECCCCCEEECCCCCCCCCEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHCCC
KLSDLKGVGIGSPGPLDAKRGVVISPPNLPGWDNVPIVDILSHKLGVKVKLENDANAAAI
EEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCEEEEECCCCCHHHH
GEHLFGAGKGIDNFVYITVSTGIGGGVIIEGKLYSGENSNAAEIGHHTINFNGPRCNCGN
HHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCHHHHCCEEEECCCCCCCCCC
YGCFEAFASGTAIARFAQEGIQNGKDTMIRDLAKDGVVKSEHVFEAAKLGDEFAKELVDN
CHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
EAFYLGVGISNIMAFYNPKKIAIGGGVSTQWDMLYDKMMETIKKKALKPNAEVCEVVRAE
CCEEEECCHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LGENVGVLGAAALLL
HCCCCCHHHHHHHHC
>Mature Secondary Structure 
GRILCGVDLGGTKISTGLVDEKGNIIRSTKIPTMAEKGPEEVIKRIEQSVYDVLKEAGL
CEEEEEECCCCCEEECCCCCCCCCEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHCCC
KLSDLKGVGIGSPGPLDAKRGVVISPPNLPGWDNVPIVDILSHKLGVKVKLENDANAAAI
EEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCEEEEECCCCCHHHH
GEHLFGAGKGIDNFVYITVSTGIGGGVIIEGKLYSGENSNAAEIGHHTINFNGPRCNCGN
HHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCHHHHCCEEEECCCCCCCCCC
YGCFEAFASGTAIARFAQEGIQNGKDTMIRDLAKDGVVKSEHVFEAAKLGDEFAKELVDN
CHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
EAFYLGVGISNIMAFYNPKKIAIGGGVSTQWDMLYDKMMETIKKKALKPNAEVCEVVRAE
CCEEEECCHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LGENVGVLGAAALLL
HCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]