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The map label for this gene is trxB [H]

Identifier: 167038722

GI number: 167038722

Start: 51995

End: 53218

Strand: Direct

Name: trxB [H]

Synonym: Teth514_0048

Alternate gene names: 167038722

Gene position: 51995-53218 (Clockwise)

Preceding gene: 167038721

Following gene: 167038723

Centisome position: 2.12

GC content: 36.36

Gene sequence:

>1224_bases
ATGGAAAAGAAAAGAGAATATTATGATGTAGTAGTTATTGGCGGTGGACCTGCTGGAATGACAGCAGCTATATATTGTGG
ACGTGCGAGACTTAAAACTCTTTTGATTGAAAAGTCTCTCGTTGGTGGCCTTGCCACATATACCAGTGAAATCGAGAATT
ATCCGGGATTTCCTGAGGGAATTGGTGGACTTGAGTTGATGAAATTATTTGAGCAACAGACTAAAAGGTTTGGCGTGCAA
ATAAAGCTTACAGATGTAAAAGGCTTGAGAATAGAAGAAGACTATAAAGTAGTTTCTACTTTCAGGGTTGATTATTATGC
TAAGGCTGTTATTATTGCGACAGGAGGCAAACCAAGGCTTACTGGTGCTAAAGGGGAAGAGAACTTTTTATACGATAAAG
GAATATCTTTTTGTGCTACCTGTGATGCGGCCTACTACACTGATAAAAAGGTTATGATAATTGGAAGCGGAGATGCAGCT
ATAGAAGAAGGAATATTCTTGACCAAGTTTGCAAGAGAAGTTCATGTATCTGTTCTTCATGATGAAGGAATAATGGATGC
CAATAAAGTAGCGCAAGAGAAGGCCTTGAAAAATGAAAAGATGATATTTCATTGGAATACAATGGTTGAAGCTTTTGAAG
GGAATGAAAGGTTGGAAAGGGTTGTCCTTAAAAATTTAAAGACAGGAGAATTAATCCCAGTAGATGTAGATGGTTGTTTC
CTGTTTATAGGTTATGTTCCTAATACGGAGATATTTAAAGGTCTAATAGACATGACACCTAAAGGTTATATCATAACAAA
TGAAAATATGGAAACTAATATTGATGGAGTATACGCAGTAGGAGATGTGAGAGATAAATTCTTGAAGCAAGTTGCTACAG
CAGTAGGAGATGGTGCAATAGCGGGTGTTATGGCAGAGAAGTATATTGAGGAAACGGATTACTTTACGAATGAAATTTTG
AAGGCTAAAGAGACAGTGTTAGCATATGTCTACAATGCTGTAGAAGCAAAAGACAGAGAATATCTTATGAAGGTTGAGGA
ATTTCATAAAAAATATGCTGATAAACTGAAAATGTGTAGGATAGATACTTATAAGTCTGACAGACTTGCTAAGAGGCTGT
ACTGTGAAAAGGTACCCTGTATTGCTGTTTTAAAAGAAGGCAAGGTGGTAAAACACATTTATAACTTAGAGGATTTTGAA
AAAGAATTGCTTAGCTGTATATAA

Upstream 100 bases:

>100_bases
GGACTAATTGGAGCGTGGATTGGAAGCAAACTTTTAGTCAAATATTTTATGTAAATAATTAGGTGGCTTGTAGCCACCTA
AATTTTAGGAGGGAGTTTGC

Downstream 100 bases:

>100_bases
GAAAATGCCCTTTTGGGCATTTCAGCTTTGTTAACAAAGAACCAAAAATTATTTAAAGTAGATATTTTGCATCGTTGCTC
CGAAGTTCCAAAGCGACAAA

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MEKKREYYDVVVIGGGPAGMTAAIYCGRARLKTLLIEKSLVGGLATYTSEIENYPGFPEGIGGLELMKLFEQQTKRFGVQ
IKLTDVKGLRIEEDYKVVSTFRVDYYAKAVIIATGGKPRLTGAKGEENFLYDKGISFCATCDAAYYTDKKVMIIGSGDAA
IEEGIFLTKFAREVHVSVLHDEGIMDANKVAQEKALKNEKMIFHWNTMVEAFEGNERLERVVLKNLKTGELIPVDVDGCF
LFIGYVPNTEIFKGLIDMTPKGYIITNENMETNIDGVYAVGDVRDKFLKQVATAVGDGAIAGVMAEKYIEETDYFTNEIL
KAKETVLAYVYNAVEAKDREYLMKVEEFHKKYADKLKMCRIDTYKSDRLAKRLYCEKVPCIAVLKEGKVVKHIYNLEDFE
KELLSCI

Sequences:

>Translated_407_residues
MEKKREYYDVVVIGGGPAGMTAAIYCGRARLKTLLIEKSLVGGLATYTSEIENYPGFPEGIGGLELMKLFEQQTKRFGVQ
IKLTDVKGLRIEEDYKVVSTFRVDYYAKAVIIATGGKPRLTGAKGEENFLYDKGISFCATCDAAYYTDKKVMIIGSGDAA
IEEGIFLTKFAREVHVSVLHDEGIMDANKVAQEKALKNEKMIFHWNTMVEAFEGNERLERVVLKNLKTGELIPVDVDGCF
LFIGYVPNTEIFKGLIDMTPKGYIITNENMETNIDGVYAVGDVRDKFLKQVATAVGDGAIAGVMAEKYIEETDYFTNEIL
KAKETVLAYVYNAVEAKDREYLMKVEEFHKKYADKLKMCRIDTYKSDRLAKRLYCEKVPCIAVLKEGKVVKHIYNLEDFE
KELLSCI
>Mature_407_residues
MEKKREYYDVVVIGGGPAGMTAAIYCGRARLKTLLIEKSLVGGLATYTSEIENYPGFPEGIGGLELMKLFEQQTKRFGVQ
IKLTDVKGLRIEEDYKVVSTFRVDYYAKAVIIATGGKPRLTGAKGEENFLYDKGISFCATCDAAYYTDKKVMIIGSGDAA
IEEGIFLTKFAREVHVSVLHDEGIMDANKVAQEKALKNEKMIFHWNTMVEAFEGNERLERVVLKNLKTGELIPVDVDGCF
LFIGYVPNTEIFKGLIDMTPKGYIITNENMETNIDGVYAVGDVRDKFLKQVATAVGDGAIAGVMAEKYIEETDYFTNEIL
KAKETVLAYVYNAVEAKDREYLMKVEEFHKKYADKLKMCRIDTYKSDRLAKRLYCEKVPCIAVLKEGKVVKHIYNLEDFE
KELLSCI

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=33.968253968254, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI87081763, Length=317, Percent_Identity=29.9684542586751, Blast_Score=114, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6320560, Length=316, Percent_Identity=37.3417721518987, Blast_Score=191, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=35.9621451104101, Blast_Score=187, Evalue=3e-48,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 45820; Mature: 45820

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKREYYDVVVIGGGPAGMTAAIYCGRARLKTLLIEKSLVGGLATYTSEIENYPGFPEG
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGGLELMKLFEQQTKRFGVQIKLTDVKGLRIEEDYKVVSTFRVDYYAKAVIIATGGKPRL
CCHHHHHHHHHHHHHHCCCEEEEECCCCCEECCCCEEEHEEEEEEEEEEEEEEECCCCCC
TGAKGEENFLYDKGISFCATCDAAYYTDKKVMIIGSGDAAIEEGIFLTKFAREVHVSVLH
CCCCCCCCEEHHCCCCEEEECCCCEECCCEEEEEECCCHHHHCCCHHHHHHHHHEEEEEE
DEGIMDANKVAQEKALKNEKMIFHWNTMVEAFEGNERLERVVLKNLKTGELIPVDVDGCF
CCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCEE
LFIGYVPNTEIFKGLIDMTPKGYIITNENMETNIDGVYAVGDVRDKFLKQVATAVGDGAI
EEEEECCCHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCHH
AGVMAEKYIEETDYFTNEILKAKETVLAYVYNAVEAKDREYLMKVEEFHKKYADKLKMCR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHE
IDTYKSDRLAKRLYCEKVPCIAVLKEGKVVKHIYNLEDFEKELLSCI
ECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHCHHHHHHHHHHCC
>Mature Secondary Structure
MEKKREYYDVVVIGGGPAGMTAAIYCGRARLKTLLIEKSLVGGLATYTSEIENYPGFPEG
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGGLELMKLFEQQTKRFGVQIKLTDVKGLRIEEDYKVVSTFRVDYYAKAVIIATGGKPRL
CCHHHHHHHHHHHHHHCCCEEEEECCCCCEECCCCEEEHEEEEEEEEEEEEEEECCCCCC
TGAKGEENFLYDKGISFCATCDAAYYTDKKVMIIGSGDAAIEEGIFLTKFAREVHVSVLH
CCCCCCCCEEHHCCCCEEEECCCCEECCCEEEEEECCCHHHHCCCHHHHHHHHHEEEEEE
DEGIMDANKVAQEKALKNEKMIFHWNTMVEAFEGNERLERVVLKNLKTGELIPVDVDGCF
CCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCEE
LFIGYVPNTEIFKGLIDMTPKGYIITNENMETNIDGVYAVGDVRDKFLKQVATAVGDGAI
EEEEECCCHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCHH
AGVMAEKYIEETDYFTNEILKAKETVLAYVYNAVEAKDREYLMKVEEFHKKYADKLKMCR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHE
IDTYKSDRLAKRLYCEKVPCIAVLKEGKVVKHIYNLEDFEKELLSCI
ECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8529640 [H]