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The map label for this gene is ribE [H]

Identifier: 167038696

GI number: 167038696

Start: 25267

End: 25890

Strand: Direct

Name: ribE [H]

Synonym: Teth514_0021

Alternate gene names: 167038696

Gene position: 25267-25890 (Clockwise)

Preceding gene: 167038695

Following gene: 167038697

Centisome position: 1.03

GC content: 32.37

Gene sequence:

>624_bases
ATGTTTACTGGAATTATAGAAGAAACAGGAACTGTTAAGAATATTACACATGGTACTTTTACAAAAATTGTTATAAAATG
TAGCAAAGTCCTTGAGGAAACAAAAATAGGTGATAGCATAGCAGTTAACGGTGTATGTTTAACTGTTACTAATATATCAG
ACGAAAGTTTTGCGGCTGATGTTATGCCTGAAACCATGAGGGCAAGTAATTTAAAAGATCTGAAAACTGGAAGCATTGTC
AATCTTGAAAGAGCACTTCAAGTTGGAAGGAGAATGGGCGGGCATATTGTAACTGGCCATATAGATTGCGTTGGAAAAAT
CATAGAGAAAAGGCAGGAAAAAAATGCTTTTATATTTAAAATAGCTATCAATGAGAAATTTACAAAATACATTGCCCGTA
AGGGAAGTATTGCGGTTGATGGTATAAGTTTAACGGTTGTTGAGGATGGATATGATTATTTTACTGTTTCAGTTATTCCA
CATACAATGCTTAAGACCACATTGGGTTATAAAGGGGTAGGAGATAGTGTAAATATCGAAGTTGATATACTTTCTAAGTA
TGTAGAAAAACTAATAGGGAAAAAGGATATAAAAGATTTATTAAAAGAAAATGGATTTATATAG

Upstream 100 bases:

>100_bases
TCGGATATAGGAAATTCAATAGAATTAAAAGATGTGGAGATTGATAGAATAGATGATGATATACTAATAACAGCATATGT
AAGAAAGTAGGTTATGGCGT

Downstream 100 bases:

>100_bases
ATGTTGATGACTTTTCTAAGTTAAGGAGGAAAGACCAATGTTTGATAGGATAGAAGATGCAATAGAAGATATAAAGCAAG
GGAAAATGATTATTGTGGTA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MFTGIIEETGTVKNITHGTFTKIVIKCSKVLEETKIGDSIAVNGVCLTVTNISDESFAADVMPETMRASNLKDLKTGSIV
NLERALQVGRRMGGHIVTGHIDCVGKIIEKRQEKNAFIFKIAINEKFTKYIARKGSIAVDGISLTVVEDGYDYFTVSVIP
HTMLKTTLGYKGVGDSVNIEVDILSKYVEKLIGKKDIKDLLKENGFI

Sequences:

>Translated_207_residues
MFTGIIEETGTVKNITHGTFTKIVIKCSKVLEETKIGDSIAVNGVCLTVTNISDESFAADVMPETMRASNLKDLKTGSIV
NLERALQVGRRMGGHIVTGHIDCVGKIIEKRQEKNAFIFKIAINEKFTKYIARKGSIAVDGISLTVVEDGYDYFTVSVIP
HTMLKTTLGYKGVGDSVNIEVDILSKYVEKLIGKKDIKDLLKENGFI
>Mature_207_residues
MFTGIIEETGTVKNITHGTFTKIVIKCSKVLEETKIGDSIAVNGVCLTVTNISDESFAADVMPETMRASNLKDLKTGSIV
NLERALQVGRRMGGHIVTGHIDCVGKIIEKRQEKNAFIFKIAINEKFTKYIARKGSIAVDGISLTVVEDGYDYFTVSVIP
HTMLKTTLGYKGVGDSVNIEVDILSKYVEKLIGKKDIKDLLKENGFI

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=193, Percent_Identity=40.9326424870466, Blast_Score=125, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319733, Length=205, Percent_Identity=41.9512195121951, Blast_Score=144, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22733; Mature: 22733

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIIEETGTVKNITHGTFTKIVIKCSKVLEETKIGDSIAVNGVCLTVTNISDESFAAD
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCEEEEEECCCCCHHHHH
VMPETMRASNLKDLKTGSIVNLERALQVGRRMGGHIVTGHIDCVGKIIEKRQEKNAFIFK
CCHHHHHHCCCCCCCCCCEECHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCEEEEE
IAINEKFTKYIARKGSIAVDGISLTVVEDGYDYFTVSVIPHTMLKTTLGYKGVGDSVNIE
EEECHHHHHHHHCCCCEEECCEEEEEEECCCCEEEEEEHHHHHHHHHCCCCCCCCCCEEE
VDILSKYVEKLIGKKDIKDLLKENGFI
HHHHHHHHHHHHCHHHHHHHHHHCCCC
>Mature Secondary Structure
MFTGIIEETGTVKNITHGTFTKIVIKCSKVLEETKIGDSIAVNGVCLTVTNISDESFAAD
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCEEEEEECCCCCHHHHH
VMPETMRASNLKDLKTGSIVNLERALQVGRRMGGHIVTGHIDCVGKIIEKRQEKNAFIFK
CCHHHHHHCCCCCCCCCCEECHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCEEEEE
IAINEKFTKYIARKGSIAVDGISLTVVEDGYDYFTVSVIPHTMLKTTLGYKGVGDSVNIE
EEECHHHHHHHHCCCCEEECCEEEEEEECCCCEEEEEEHHHHHHHHHCCCCCCCCCCEEE
VDILSKYVEKLIGKKDIKDLLKENGFI
HHHHHHHHHHHHCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]