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The map label for this gene is yicI [C]

Identifier: 167038681

GI number: 167038681

Start: 4482

End: 6740

Strand: Direct

Name: yicI [C]

Synonym: Teth514_0006

Alternate gene names: 167038681

Gene position: 4482-6740 (Clockwise)

Preceding gene: 167038680

Following gene: 167038684

Centisome position: 0.18

GC content: 33.33

Gene sequence:

>2259_bases
TTGTATCAAAAAACATCAGAAGGAATTGTTGTGAGAAATGAAGGAAAGAAGTTAGAGCTTAGAGTATTAGGTGATAAAAT
TATTAACGTTTTTGTAAGTGATAAAGAGGAAAAAAGAAAGGATACAATTGCGATAGAAAGGAAAGAATACGATATTCCTG
AGTTCAGTGTAAGAAAAGAATTAGAAAGTATATTAATTGAAACTGATTCTTTAAAAGTAAAAATAAATAAAAATGACCTT
TCTGTGAGTTTCTTAGATAAAAATGAAAATATAATTAATGAGGATTACAATGGAGGAGTAAAATTTAGTGAAACAGATGT
TAGATGCTATAAAAAGTTAAGAGAAGACCATTTTTACGGTTTTGGAGAAAAAGCAGGATATCTCGACAAAAAAGGCGAAA
GGTTAGAGATGTGGAATACAGATGAATTTATGACTCACAACCAGACTACAAAACTTTTATATGAGTCTTACCCTTTTTTC
ATAGGAATGAACGATTATCACACTTATGGAATATTTTTAGACAATAGCTTTAGGTCTTTTTTTGATATGGGACAGGAATG
CCAAGAATACTATTATTTTGGGGCCTATGGAGGTCAAATGAATTATTACTTTATTTATGGAGAAGACATAAAAGAGGTTG
TAGAGAATTATACATATCTCACTGGAAGGATAAATCTTCCACCTTTATGGGCATTGGGAAATCAGCAGAGCAGGTACAGC
TATACTCCACAAGAGAGAGTACTGGAGATTGCAAAAACTTTTAGAGAAAAAGATATTCCTTGTGACGTGATATATCTCGA
TATAGATTACATGGAAGGATATAGAGTTTTCACATGGAATAAAGATACATTTAAAAATTATAAGGAAATGCTAAAGCAGC
TTAAAGAAATGGGATTTAAAGTAGTGACGATTGTAGATCCAGGAGTTAAGAGGGATTACGACTACCATGTTTACAGAGAA
GGAATTGAGGAGGATTATTTTGTAAAGGATAAGTATGGTATAACCTATGTTGGAAAAGTATGGCCAGGGGAAGCTTGTTT
TCCTGACTTTTTACAAGAAGAAGTGAGATATTGGTGGGGGGAAAAGCACAGAGAATTTATAAAGGATGGAATTGATGGTA
TATGGAATGATATGAATGAGCCAGCTGTGTTTGAAACTCCTACTAAAACTATGCCAGAGGATAATATTCATATTTTAGAT
GGAGAAAAGGTACTTCACAAAGAAGCCCATAACGTTTATGCTAATTATATGGCTATGGCCACAAGAGATGGTTTACTAAG
GATAAGACCTAATGAAAGGCCTTTTGTGTTGACAAGAGCTGCTTTTTCAGGAATACAAAGGTATGCGGCAATGTGGACAG
GAGACAACAGAAGCTTGTACGAACACCTTCTTATGATGATGCCTATGTTGATAAATATTGGGCTTTCTGGACAACCGTTT
GCAGGAGCCGATGTAGGGGGATTTGAGGGAGATTGTCACGAAGAACTTTTTATAAGGTGGATAGAGGCAGCTACCTTTAC
TCCCTTTTTAAGAGTGCATTCTGCAATAGGTACTAAAGACCAAGAGCCCTGGTCTTTCGGAAAAAGGTGTGAGGATATAT
CGCGAAAGTACATAAAAATGAGATATGAGATTTTACCTTACTTATACGATTTGTTTTACATCGCCTCCCAAAAAGGTTAT
CCTATAATGAGGCCATTGGTTTTTGAGTATCAAGAAGATGAAAATACTCATAAAATATACGATGAATTTCTGTTAGGAGA
TAATTTATTGGTTGCGCCTATATACTTACCTTCTAAAGAAAAAAGAGAAGTGTATTTGCCAAAAGGAATATGGTATGATT
ACTGGACTGGAAAAGAATTTAAAGGAGAAAGCTATTATCTTGTGGATGCTCCTATAGATATAATACCTCTTTTTGTAAAA
GAAGGAGGAATATTATTAAAGCGTGAGCCTCAGTCCTTTGTAGAAGAAAAGGAAATAAAAGAGATAATAGTGGAAATTTA
TAGAGGAGAAGAAGGGCATTATCTCCATTATGAAGACGATGGAAAGTCCTTTGATTATACTAAAGGGGTTTATAACCTCT
TCGATATAAGTTTTTGTTATAAAGAAGGAAGGATGGATATAAAATTTGATAAAATTCACTTTGGCTATGACAAAGGAGTT
AAAAAGTATAAATTTATATTTAAAAATTTTGGTGATATTAAAGAGATTAAGATAAATGGTGAAAAAGTTGGGAAGGAAAA
TTGTGAAATTGAATTATAA

Upstream 100 bases:

>100_bases
CACAGAAAGGGATAAGAGGAGTATTATTTATTTATCACCAATTTCTGCTTTTACCCTTATAAGAAGGACACAAAAAATAG
AGGATTAGGGAGGTATTAAA

Downstream 100 bases:

>100_bases
AATAGAGGCAAAAGCCTCTATTTTTTTACAAATCTTTCTATTAAAGATTGTTTAGCTTGTTGTTCTAAGGAGTCATCCAA
AGGAGTTAATTCTACTTTGC

Product: alpha-glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 752; Mature: 752

Protein sequence:

>752_residues
MYQKTSEGIVVRNEGKKLELRVLGDKIINVFVSDKEEKRKDTIAIERKEYDIPEFSVRKELESILIETDSLKVKINKNDL
SVSFLDKNENIINEDYNGGVKFSETDVRCYKKLREDHFYGFGEKAGYLDKKGERLEMWNTDEFMTHNQTTKLLYESYPFF
IGMNDYHTYGIFLDNSFRSFFDMGQECQEYYYFGAYGGQMNYYFIYGEDIKEVVENYTYLTGRINLPPLWALGNQQSRYS
YTPQERVLEIAKTFREKDIPCDVIYLDIDYMEGYRVFTWNKDTFKNYKEMLKQLKEMGFKVVTIVDPGVKRDYDYHVYRE
GIEEDYFVKDKYGITYVGKVWPGEACFPDFLQEEVRYWWGEKHREFIKDGIDGIWNDMNEPAVFETPTKTMPEDNIHILD
GEKVLHKEAHNVYANYMAMATRDGLLRIRPNERPFVLTRAAFSGIQRYAAMWTGDNRSLYEHLLMMMPMLINIGLSGQPF
AGADVGGFEGDCHEELFIRWIEAATFTPFLRVHSAIGTKDQEPWSFGKRCEDISRKYIKMRYEILPYLYDLFYIASQKGY
PIMRPLVFEYQEDENTHKIYDEFLLGDNLLVAPIYLPSKEKREVYLPKGIWYDYWTGKEFKGESYYLVDAPIDIIPLFVK
EGGILLKREPQSFVEEKEIKEIIVEIYRGEEGHYLHYEDDGKSFDYTKGVYNLFDISFCYKEGRMDIKFDKIHFGYDKGV
KKYKFIFKNFGDIKEIKINGEKVGKENCEIEL

Sequences:

>Translated_752_residues
MYQKTSEGIVVRNEGKKLELRVLGDKIINVFVSDKEEKRKDTIAIERKEYDIPEFSVRKELESILIETDSLKVKINKNDL
SVSFLDKNENIINEDYNGGVKFSETDVRCYKKLREDHFYGFGEKAGYLDKKGERLEMWNTDEFMTHNQTTKLLYESYPFF
IGMNDYHTYGIFLDNSFRSFFDMGQECQEYYYFGAYGGQMNYYFIYGEDIKEVVENYTYLTGRINLPPLWALGNQQSRYS
YTPQERVLEIAKTFREKDIPCDVIYLDIDYMEGYRVFTWNKDTFKNYKEMLKQLKEMGFKVVTIVDPGVKRDYDYHVYRE
GIEEDYFVKDKYGITYVGKVWPGEACFPDFLQEEVRYWWGEKHREFIKDGIDGIWNDMNEPAVFETPTKTMPEDNIHILD
GEKVLHKEAHNVYANYMAMATRDGLLRIRPNERPFVLTRAAFSGIQRYAAMWTGDNRSLYEHLLMMMPMLINIGLSGQPF
AGADVGGFEGDCHEELFIRWIEAATFTPFLRVHSAIGTKDQEPWSFGKRCEDISRKYIKMRYEILPYLYDLFYIASQKGY
PIMRPLVFEYQEDENTHKIYDEFLLGDNLLVAPIYLPSKEKREVYLPKGIWYDYWTGKEFKGESYYLVDAPIDIIPLFVK
EGGILLKREPQSFVEEKEIKEIIVEIYRGEEGHYLHYEDDGKSFDYTKGVYNLFDISFCYKEGRMDIKFDKIHFGYDKGV
KKYKFIFKNFGDIKEIKINGEKVGKENCEIEL
>Mature_752_residues
MYQKTSEGIVVRNEGKKLELRVLGDKIINVFVSDKEEKRKDTIAIERKEYDIPEFSVRKELESILIETDSLKVKINKNDL
SVSFLDKNENIINEDYNGGVKFSETDVRCYKKLREDHFYGFGEKAGYLDKKGERLEMWNTDEFMTHNQTTKLLYESYPFF
IGMNDYHTYGIFLDNSFRSFFDMGQECQEYYYFGAYGGQMNYYFIYGEDIKEVVENYTYLTGRINLPPLWALGNQQSRYS
YTPQERVLEIAKTFREKDIPCDVIYLDIDYMEGYRVFTWNKDTFKNYKEMLKQLKEMGFKVVTIVDPGVKRDYDYHVYRE
GIEEDYFVKDKYGITYVGKVWPGEACFPDFLQEEVRYWWGEKHREFIKDGIDGIWNDMNEPAVFETPTKTMPEDNIHILD
GEKVLHKEAHNVYANYMAMATRDGLLRIRPNERPFVLTRAAFSGIQRYAAMWTGDNRSLYEHLLMMMPMLINIGLSGQPF
AGADVGGFEGDCHEELFIRWIEAATFTPFLRVHSAIGTKDQEPWSFGKRCEDISRKYIKMRYEILPYLYDLFYIASQKGY
PIMRPLVFEYQEDENTHKIYDEFLLGDNLLVAPIYLPSKEKREVYLPKGIWYDYWTGKEFKGESYYLVDAPIDIIPLFVK
EGGILLKREPQSFVEEKEIKEIIVEIYRGEEGHYLHYEDDGKSFDYTKGVYNLFDISFCYKEGRMDIKFDKIHFGYDKGV
KKYKFIFKNFGDIKEIKINGEKVGKENCEIEL

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI38202257, Length=622, Percent_Identity=35.3697749196142, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI88900491, Length=622, Percent_Identity=35.3697749196142, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI66346737, Length=605, Percent_Identity=34.3801652892562, Blast_Score=361, Evalue=1e-99,
Organism=Homo sapiens, GI221316699, Length=680, Percent_Identity=31.1764705882353, Blast_Score=318, Evalue=2e-86,
Organism=Homo sapiens, GI119393895, Length=640, Percent_Identity=30.15625, Blast_Score=307, Evalue=2e-83,
Organism=Homo sapiens, GI119393893, Length=640, Percent_Identity=30.15625, Blast_Score=307, Evalue=2e-83,
Organism=Homo sapiens, GI119393891, Length=640, Percent_Identity=30.15625, Blast_Score=307, Evalue=2e-83,
Organism=Homo sapiens, GI157364974, Length=715, Percent_Identity=29.7902097902098, Blast_Score=278, Evalue=1e-74,
Organism=Homo sapiens, GI310115361, Length=644, Percent_Identity=27.3291925465839, Blast_Score=235, Evalue=1e-61,
Organism=Homo sapiens, GI153791946, Length=466, Percent_Identity=25.5364806866953, Blast_Score=132, Evalue=2e-30,
Organism=Escherichia coli, GI2367256, Length=593, Percent_Identity=25.8010118043845, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI2367323, Length=641, Percent_Identity=24.0249609984399, Blast_Score=163, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71991189, Length=674, Percent_Identity=34.1246290801187, Blast_Score=367, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17560798, Length=592, Percent_Identity=33.445945945946, Blast_Score=353, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI17560800, Length=592, Percent_Identity=33.445945945946, Blast_Score=353, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI71985706, Length=700, Percent_Identity=26.5714285714286, Blast_Score=237, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI32563849, Length=686, Percent_Identity=26.3848396501458, Blast_Score=209, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6319706, Length=596, Percent_Identity=33.5570469798658, Blast_Score=312, Evalue=1e-85,
Organism=Drosophila melanogaster, GI24643749, Length=588, Percent_Identity=33.5034013605442, Blast_Score=328, Evalue=6e-90,
Organism=Drosophila melanogaster, GI24643753, Length=588, Percent_Identity=33.5034013605442, Blast_Score=328, Evalue=6e-90,
Organism=Drosophila melanogaster, GI24643751, Length=588, Percent_Identity=33.5034013605442, Blast_Score=328, Evalue=6e-90,
Organism=Drosophila melanogaster, GI24643746, Length=588, Percent_Identity=33.5034013605442, Blast_Score=328, Evalue=6e-90,
Organism=Drosophila melanogaster, GI21357605, Length=588, Percent_Identity=33.5034013605442, Blast_Score=328, Evalue=6e-90,
Organism=Drosophila melanogaster, GI24650054, Length=408, Percent_Identity=26.7156862745098, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28571440, Length=380, Percent_Identity=23.1578947368421, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28571438, Length=382, Percent_Identity=23.2984293193717, Blast_Score=73, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 89066; Mature: 89066

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00129 GLYCOSYL_HYDROL_F31_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQKTSEGIVVRNEGKKLELRVLGDKIINVFVSDKEEKRKDTIAIERKEYDIPEFSVRKE
CCCCCCCCEEEECCCCEEEEEEECCEEEEEEECCCHHHCCCCEEEEECCCCCCCHHHHHH
LESILIETDSLKVKINKNDLSVSFLDKNENIINEDYNGGVKFSETDVRCYKKLREDHFYG
HHHHHEECCCEEEEEECCCEEEEEECCCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCC
FGEKAGYLDKKGERLEMWNTDEFMTHNQTTKLLYESYPFFIGMNDYHTYGIFLDNSFRSF
CCCCCCCCCCCCCEEEECCCCHHHCCCCHHHHHHCCCCEEEECCCCEEEEEEEECCHHHH
FDMGQECQEYYYFGAYGGQMNYYFIYGEDIKEVVENYTYLTGRINLPPLWALGNQQSRYS
HHCCHHHHHCEEEEEECCCEEEEEEECHHHHHHHHCCEEEEEECCCCCEEECCCCCCCCC
YTPQERVLEIAKTFREKDIPCDVIYLDIDYMEGYRVFTWNKDTFKNYKEMLKQLKEMGFK
CCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHCCCE
VVTIVDPGVKRDYDYHVYREGIEEDYFVKDKYGITYVGKVWPGEACFPDFLQEEVRYWWG
EEEEECCCCCCCCCHHHHHCCCCCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHC
EKHREFIKDGIDGIWNDMNEPAVFETPTKTMPEDNIHILDGEKVLHKEAHNVYANYMAMA
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHEE
TRDGLLRIRPNERPFVLTRAAFSGIQRYAAMWTGDNRSLYEHLLMMMPMLINIGLSGQPF
ECCCEEEECCCCCCEEEEHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCCCCC
AGADVGGFEGDCHEELFIRWIEAATFTPFLRVHSAIGTKDQEPWSFGKRCEDISRKYIKM
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
RYEILPYLYDLFYIASQKGYPIMRPLVFEYQEDENTHKIYDEFLLGDNLLVAPIYLPSKE
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCC
KREVYLPKGIWYDYWTGKEFKGESYYLVDAPIDIIPLFVKEGGILLKREPQSFVEEKEIK
CCEEECCCCCEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCEEEEECCHHHHHHHHHH
EIIVEIYRGEEGHYLHYEDDGKSFDYTKGVYNLFDISFCYKEGRMDIKFDKIHFGYDKGV
HHHHHHHCCCCCCEEEECCCCCCCCHHHCHHHHHHHEEHHHCCCCEEEEEEEEECHHHCH
KKYKFIFKNFGDIKEIKINGEKVGKENCEIEL
HHHHHHHHCCCCEEEEEECCHHCCCCCCCEEC
>Mature Secondary Structure
MYQKTSEGIVVRNEGKKLELRVLGDKIINVFVSDKEEKRKDTIAIERKEYDIPEFSVRKE
CCCCCCCCEEEECCCCEEEEEEECCEEEEEEECCCHHHCCCCEEEEECCCCCCCHHHHHH
LESILIETDSLKVKINKNDLSVSFLDKNENIINEDYNGGVKFSETDVRCYKKLREDHFYG
HHHHHEECCCEEEEEECCCEEEEEECCCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCC
FGEKAGYLDKKGERLEMWNTDEFMTHNQTTKLLYESYPFFIGMNDYHTYGIFLDNSFRSF
CCCCCCCCCCCCCEEEECCCCHHHCCCCHHHHHHCCCCEEEECCCCEEEEEEEECCHHHH
FDMGQECQEYYYFGAYGGQMNYYFIYGEDIKEVVENYTYLTGRINLPPLWALGNQQSRYS
HHCCHHHHHCEEEEEECCCEEEEEEECHHHHHHHHCCEEEEEECCCCCEEECCCCCCCCC
YTPQERVLEIAKTFREKDIPCDVIYLDIDYMEGYRVFTWNKDTFKNYKEMLKQLKEMGFK
CCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHCCCE
VVTIVDPGVKRDYDYHVYREGIEEDYFVKDKYGITYVGKVWPGEACFPDFLQEEVRYWWG
EEEEECCCCCCCCCHHHHHCCCCCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHC
EKHREFIKDGIDGIWNDMNEPAVFETPTKTMPEDNIHILDGEKVLHKEAHNVYANYMAMA
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHEE
TRDGLLRIRPNERPFVLTRAAFSGIQRYAAMWTGDNRSLYEHLLMMMPMLINIGLSGQPF
ECCCEEEECCCCCCEEEEHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCCCCC
AGADVGGFEGDCHEELFIRWIEAATFTPFLRVHSAIGTKDQEPWSFGKRCEDISRKYIKM
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
RYEILPYLYDLFYIASQKGYPIMRPLVFEYQEDENTHKIYDEFLLGDNLLVAPIYLPSKE
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCC
KREVYLPKGIWYDYWTGKEFKGESYYLVDAPIDIIPLFVKEGGILLKREPQSFVEEKEIK
CCEEECCCCCEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCEEEEECCHHHHHHHHHH
EIIVEIYRGEEGHYLHYEDDGKSFDYTKGVYNLFDISFCYKEGRMDIKFDKIHFGYDKGV
HHHHHHHCCCCCCEEEECCCCCCCCHHHCHHHHHHHEEHHHCCCCEEEEEEEEECHHHCH
KKYKFIFKNFGDIKEIKINGEKVGKENCEIEL
HHHHHHHHCCCCEEEEEECCHHCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]