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The map label for this gene is gcvT [H]

Identifier: 163844858

GI number: 163844858

Start: 699964

End: 701067

Strand: Reverse

Name: gcvT [H]

Synonym: BSUIS_B0717

Alternate gene names: 163844858

Gene position: 701067-699964 (Counterclockwise)

Preceding gene: 163844860

Following gene: 163844857

Centisome position: 50.05

GC content: 61.41

Gene sequence:

>1104_bases
ATGGGCGATACCGCACATTTGAATACCCTGCCGTTGCAGGATCTGCATGAAAAGGCTGGCGCGCGCTTCGGCGGCTTTGC
CGGCTGGAACATGCCAATCACCTATCCGCTGGGTGTGATGAAGGAACATCTTCATACGCGCGACCATGCGGGCCTCTTCG
ACATTTCCCACATGAAGCTGGTGGAAGTTTCCGGCGCGGATGCCGCCGCGCTTCTCGCCGAGACCTGCCCGCTCGATCCG
ACGATCCTGAAGACGGGCCAGTCGAAATATACGTTCTTCCTCAATGATAATGGCGGCGTGCTGGATGATCTCATCGTCAC
GCGCCTTGGCGAAGACCGTTTCATGGTTGTTGCCAATGCGGGCAATGCCGATGCCGACATCGAGCATCTCAATGAAGCCG
CGTCGGGCAAGGCCGTAAAGGTTAATCCGCTCGACCGTGTTTTCCTTGCTTTGCAGGGGCCGGAAGCAGAAGCTGTCATC
ACCGATGCCGGTCTGCCGGGCGCCGATCTTGCCTTCATGAGCGGTTTCGAGCCGAAACAGGGCTGGTTCATGACCCGTTC
GGGCTATACCGGCGAAGACGGTTTCGAGATTGGCCTGCCTGCCGATGAAGCCCGTGCGCTGGCCGAAAAGCTTCTTGCCG
ATGAACGTGTCGAATGGATCGGCCTTGCCGCCCGCGATTCCTTACGCCTCGAAGCGGGCCTCTGCCTGCACGGTCAGGAC
ATCACGCCGGAAACCGATCCGGTTTCGGCTGGCCTCACCTGGGCGATCACTAAGGCTGTGCGCGAAAAAGCCGCCTTCAA
CGGCGCGAAAGCCGTTCTCGACGCCATTGCCAAAGGCGCCAGCGCCAAGCGCGTCGGCCTCAAGCCGGAAGGCCGCCAGC
CGGTGCGCGCCGGGGCCGACCTTTTCGACGAAAGTGGCCGCCAGATCGGCACCGTCACCTCGGGCGGCTTTGGCCCTTCC
GCCGGTTTCCCGGTCGCCATGGGCTATGTCGAGGCAAGCCTCGCCACCCCCGGCACCCGTGTTTTTGCAGATGTTCGCGG
CAACAAGGTTCCCGTTGACGTCCACGCACTTCCCTTCACACCGCATCGCTATCGCAAAGGATGA

Upstream 100 bases:

>100_bases
ATGGCTTTATATATAGCCATGCGAGTCTCTCAGGCCTGAGACAGAGGGGCACGAACCAACCGCATTTTGCGGAAGGCATA
CGTGTGTCTCTGGAGTTGTT

Downstream 100 bases:

>100_bases
TTTCCATGGCCAATATCCTGTTCACCGAAGATCATGAGTGGATCAACGTCGAAAACGGCGTTGCCACGGTTGGCATCACG
ATCCACGCACAGGAACAGCT

Product: glycine cleavage system aminomethyltransferase T

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MGDTAHLNTLPLQDLHEKAGARFGGFAGWNMPITYPLGVMKEHLHTRDHAGLFDISHMKLVEVSGADAAALLAETCPLDP
TILKTGQSKYTFFLNDNGGVLDDLIVTRLGEDRFMVVANAGNADADIEHLNEAASGKAVKVNPLDRVFLALQGPEAEAVI
TDAGLPGADLAFMSGFEPKQGWFMTRSGYTGEDGFEIGLPADEARALAEKLLADERVEWIGLAARDSLRLEAGLCLHGQD
ITPETDPVSAGLTWAITKAVREKAAFNGAKAVLDAIAKGASAKRVGLKPEGRQPVRAGADLFDESGRQIGTVTSGGFGPS
AGFPVAMGYVEASLATPGTRVFADVRGNKVPVDVHALPFTPHRYRKG

Sequences:

>Translated_367_residues
MGDTAHLNTLPLQDLHEKAGARFGGFAGWNMPITYPLGVMKEHLHTRDHAGLFDISHMKLVEVSGADAAALLAETCPLDP
TILKTGQSKYTFFLNDNGGVLDDLIVTRLGEDRFMVVANAGNADADIEHLNEAASGKAVKVNPLDRVFLALQGPEAEAVI
TDAGLPGADLAFMSGFEPKQGWFMTRSGYTGEDGFEIGLPADEARALAEKLLADERVEWIGLAARDSLRLEAGLCLHGQD
ITPETDPVSAGLTWAITKAVREKAAFNGAKAVLDAIAKGASAKRVGLKPEGRQPVRAGADLFDESGRQIGTVTSGGFGPS
AGFPVAMGYVEASLATPGTRVFADVRGNKVPVDVHALPFTPHRYRKG
>Mature_366_residues
GDTAHLNTLPLQDLHEKAGARFGGFAGWNMPITYPLGVMKEHLHTRDHAGLFDISHMKLVEVSGADAAALLAETCPLDPT
ILKTGQSKYTFFLNDNGGVLDDLIVTRLGEDRFMVVANAGNADADIEHLNEAASGKAVKVNPLDRVFLALQGPEAEAVIT
DAGLPGADLAFMSGFEPKQGWFMTRSGYTGEDGFEIGLPADEARALAEKLLADERVEWIGLAARDSLRLEAGLCLHGQDI
TPETDPVSAGLTWAITKAVREKAAFNGAKAVLDAIAKGASAKRVGLKPEGRQPVRAGADLFDESGRQIGTVTSGGFGPSA
GFPVAMGYVEASLATPGTRVFADVRGNKVPVDVHALPFTPHRYRKG

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=370, Percent_Identity=40.5405405405405, Blast_Score=249, Evalue=2e-66,
Organism=Homo sapiens, GI257796258, Length=351, Percent_Identity=40.7407407407407, Blast_Score=237, Evalue=1e-62,
Organism=Homo sapiens, GI257796254, Length=365, Percent_Identity=37.5342465753425, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI257796256, Length=315, Percent_Identity=40, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI24797151, Length=350, Percent_Identity=24.5714285714286, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI197927446, Length=323, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI21361378, Length=323, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789272, Length=354, Percent_Identity=33.0508474576271, Blast_Score=158, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17560118, Length=375, Percent_Identity=38.9333333333333, Blast_Score=223, Evalue=9e-59,
Organism=Caenorhabditis elegans, GI32563613, Length=314, Percent_Identity=26.7515923566879, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320222, Length=384, Percent_Identity=35.9375, Blast_Score=209, Evalue=4e-55,
Organism=Drosophila melanogaster, GI20129441, Length=371, Percent_Identity=39.3530997304582, Blast_Score=245, Evalue=3e-65,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 38896; Mature: 38765

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDTAHLNTLPLQDLHEKAGARFGGFAGWNMPITYPLGVMKEHLHTRDHAGLFDISHMKL
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHCCCCCCEEEECCEEE
VEVSGADAAALLAETCPLDPTILKTGQSKYTFFLNDNGGVLDDLIVTRLGEDRFMVVANA
EEECCCCHHHHHHHHCCCCHHHEECCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEC
GNADADIEHLNEAASGKAVKVNPLDRVFLALQGPEAEAVITDAGLPGADLAFMSGFEPKQ
CCCCCHHHHHHHHHCCCEEEECCCCEEEEEEECCCCCEEEEECCCCCCCCHHHCCCCCCC
GWFMTRSGYTGEDGFEIGLPADEARALAEKLLADERVEWIGLAARDSLRLEAGLCLHGQD
CEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHCCEEEEEEECCCCEEEECCEEEECCC
ITPETDPVSAGLTWAITKAVREKAAFNGAKAVLDAIAKGASAKRVGLKPEGRQPVRAGAD
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
LFDESGRQIGTVTSGGFGPSAGFPVAMGYVEASLATPGTRVFADVRGNKVPVDVHALPFT
HHHHCCCEEEEEECCCCCCCCCCCEEEHEEEHHCCCCCCEEEEECCCCCCEEEEEECCCC
PHRYRKG
CHHCCCC
>Mature Secondary Structure 
GDTAHLNTLPLQDLHEKAGARFGGFAGWNMPITYPLGVMKEHLHTRDHAGLFDISHMKL
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHCCCCCCEEEECCEEE
VEVSGADAAALLAETCPLDPTILKTGQSKYTFFLNDNGGVLDDLIVTRLGEDRFMVVANA
EEECCCCHHHHHHHHCCCCHHHEECCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEC
GNADADIEHLNEAASGKAVKVNPLDRVFLALQGPEAEAVITDAGLPGADLAFMSGFEPKQ
CCCCCHHHHHHHHHCCCEEEECCCCEEEEEEECCCCCEEEEECCCCCCCCHHHCCCCCCC
GWFMTRSGYTGEDGFEIGLPADEARALAEKLLADERVEWIGLAARDSLRLEAGLCLHGQD
CEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHCCEEEEEEECCCCEEEECCEEEECCC
ITPETDPVSAGLTWAITKAVREKAAFNGAKAVLDAIAKGASAKRVGLKPEGRQPVRAGAD
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
LFDESGRQIGTVTSGGFGPSAGFPVAMGYVEASLATPGTRVFADVRGNKVPVDVHALPFT
HHHHCCCEEEEEECCCCCCCCCCCEEEHEEEHHCCCCCCEEEEECCCCCCEEEEEECCCC
PHRYRKG
CHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA