Click here to switch to the map view.

The map label for this gene is rfbC [C]

Identifier: 163844603

GI number: 163844603

Start: 426370

End: 426894

Strand: Reverse

Name: rfbC [C]

Synonym: BSUIS_B0438

Alternate gene names: 163844603

Gene position: 426894-426370 (Counterclockwise)

Preceding gene: 163844608

Following gene: 163844595

Centisome position: 30.47

GC content: 59.05

Gene sequence:

>525_bases
ATGCATTTCACTCCGCTCAACATCAACGGCGCATGGTCCATCGAGCCGGAACGGCTGAAGGACGAGCGCGGCTGGTTCGC
GCGGGTCTATTGCGAGGCGGCCTTTGCCGAACGGAAGCTGGAAACACACTTTCCCCAGCACAGCCTTTCCTTCTCGCGCG
AGAAGGGAACCCTGCGCGGACTGCATTATCAGAACGAGCCGCATAGCGAGACGAAACTCGTCACCTGCCTGCAAGGCATC
GTCTGGGATGTGCTGGTGGATCTTCGCCCCCACTCACCCACTTATCGGCGGTGGGCGGGGGTGGAACTTTCAGCCGAAAA
CGGTGTGCAACTCTATATACCGGAAGGCTGCGCCCACGGTTTCCAGACGCTGACGGATGATGTCCTCATCCGCTACATGA
TCTCGAAGCCCTATGCGCCCGATCATGCCGCCGGCATCCGCTATGACGATCCAGCCCTCGACATTCCATGGCCGGAGAAG
CCCAGCGTCATTTCGCAAAAAGATCTTGGCTGGCCGTTTCTTTGA

Upstream 100 bases:

>100_bases
CTGCCTCCACCAAAAGGCTATCTGGCTGCTTCAAAGAAAGTTCTATCGCCGTAAGGACAGGCTGGCAGAATGCAAAAATG
CAGCAATCGGGGGCAGGCTC

Downstream 100 bases:

>100_bases
TCAATCCCGCATCGCGAAGCCGGTCGGCCGCATCGGCAAGCATGGCGAAGGGCAGTTTCGACCGCTCCGCCATGTCGAGA
ATCGAATAGCCGCCATCGGC

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MHFTPLNINGAWSIEPERLKDERGWFARVYCEAAFAERKLETHFPQHSLSFSREKGTLRGLHYQNEPHSETKLVTCLQGI
VWDVLVDLRPHSPTYRRWAGVELSAENGVQLYIPEGCAHGFQTLTDDVLIRYMISKPYAPDHAAGIRYDDPALDIPWPEK
PSVISQKDLGWPFL

Sequences:

>Translated_174_residues
MHFTPLNINGAWSIEPERLKDERGWFARVYCEAAFAERKLETHFPQHSLSFSREKGTLRGLHYQNEPHSETKLVTCLQGI
VWDVLVDLRPHSPTYRRWAGVELSAENGVQLYIPEGCAHGFQTLTDDVLIRYMISKPYAPDHAAGIRYDDPALDIPWPEK
PSVISQKDLGWPFL
>Mature_174_residues
MHFTPLNINGAWSIEPERLKDERGWFARVYCEAAFAERKLETHFPQHSLSFSREKGTLRGLHYQNEPHSETKLVTCLQGI
VWDVLVDLRPHSPTYRRWAGVELSAENGVQLYIPEGCAHGFQTLTDDVLIRYMISKPYAPDHAAGIRYDDPALDIPWPEK
PSVISQKDLGWPFL

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=170, Percent_Identity=35.8823529411765, Blast_Score=115, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17550412, Length=160, Percent_Identity=38.75, Blast_Score=96, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20001; Mature: 20001

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFTPLNINGAWSIEPERLKDERGWFARVYCEAAFAERKLETHFPQHSLSFSREKGTLRG
CCCCCCCCCCEECCCHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEC
LHYQNEPHSETKLVTCLQGIVWDVLVDLRPHSPTYRRWAGVELSAENGVQLYIPEGCAHG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCEEEECCCCEEEEECCHHHHH
FQTLTDDVLIRYMISKPYAPDHAAGIRYDDPALDIPWPEKPSVISQKDLGWPFL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHFTPLNINGAWSIEPERLKDERGWFARVYCEAAFAERKLETHFPQHSLSFSREKGTLRG
CCCCCCCCCCEECCCHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEC
LHYQNEPHSETKLVTCLQGIVWDVLVDLRPHSPTYRRWAGVELSAENGVQLYIPEGCAHG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCEEEECCCCEEEEECCHHHHH
FQTLTDDVLIRYMISKPYAPDHAAGIRYDDPALDIPWPEKPSVISQKDLGWPFL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]