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The map label for this gene is wecA [H]

Identifier: 163844595

GI number: 163844595

Start: 414588

End: 415715

Strand: Reverse

Name: wecA [H]

Synonym: BSUIS_B0429

Alternate gene names: 163844595

Gene position: 415715-414588 (Counterclockwise)

Preceding gene: 163844603

Following gene: 163844594

Centisome position: 29.68

GC content: 59.57

Gene sequence:

>1128_bases
ATGACAAGTCTTTCCTGGATCACGCTTCTGGCTTTTGTCCTGTCGGTGGCCTTCTCCTTCTGCATAGCTTTTCGTGGGCT
TGCGCGCGAATGGTATCTGATCGACCTGCCCGATTACCGCAAAAGACATGAAGGTGCCGTCCCGCTTTGCGGGGGTATCG
CAATCTTCCTGTCCTTTTTCCTGACAGCTTCACTGGTAAAAGACGGTGCGGGACATGCAGATGCACTGGTGATGATGCCG
GGGCTGACGATCATCCTCGGCACGGGGGTGCTGGATGATCGCTTCAGGCTGCCGGTGACGCCGCGTTTTGCAATCCAGCT
TTTTGCAGCGGTTCTCATCATCGCCATGGCGGGGGTACAGCAGGTCTTTCTGGACCTCAACCCCTCCTTTATCGACGATA
GCGGCAATATATTTGCCTTTGAACGGCTGGGCGGCCCCTTTCTATTGCTTTTCGCCGTGGCCTTCATCGTCGGCCTTGTC
AATGCGGTCAATATGAGCGACGGCGTGGACGGGCTTGCAGGATCGGCAAGTGCAGCCTCCTTCTTCTGGCTCGCCGTTAT
CAGCTTCGACATCGGCGAACACCGGCTGGGCCTGCAATCGCTGGCGCTTGTCGCCGCCTGCCTTGGTTTCCTCGTTTTCA
ACATGCGCCATAGGTGGCGGGCAAAGGCAAGCCTCTTTCTGGGTGACGGCGGCAGCACGCTTCTGGGGGCCGCCCTTGCG
GGAATGGTGTTGATCCTCTCCAGCGGCAGGCAAGCAATTGCTTTCCCTGTCTTGCTTTGGATCGTGATTGTGCCGGTCCT
CGATACGCTTAGCCTCATCGTAAGAAGGCTCGCGGCGCGGCGCAGCCCTTTTTCCGCCGACCGGCAGCATCTCCATCACC
TGCTGATGGATGCCGGGCTGACCTGCGGGCAGACCGCAATCATCGTCATGGCGCTCAACCTGATTGCAGGCGCAACAGCC
TATACGGCTATTCGCCTCGACCTGCCCGGCTGGCTGATGGCGCTGGCGCTTCTCGCACCGGCCATGGCGCACCTAGCCTT
CATCCTGCGTTGCACCAGAGGTCCGCGCATCGCCGATCCCGCGCAGGCGGCAAAACCGAACATCACCTTTCCGGGGACCA
CGACATGA

Upstream 100 bases:

>100_bases
GAAAGAGGTAGGCCGCTCGCTCAATAGCCAAGTCGTGAGCCGTGGCCGGACCCGGTAAAAATCCTTCCAGAACGACTTTC
GCTCGCTGCTTGGAGGAGGC

Downstream 100 bases:

>100_bases
CCGTTTCCGTGCTCATCATGACGCTCAACGAGGAAGCCAACCTGCCGGCATGTCTGGCTTCGCTCGACTGGTGCGATGAT
ATCGTCGTGCTGGATTCATT

Product: hypothetical protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTSLSWITLLAFVLSVAFSFCIAFRGLAREWYLIDLPDYRKRHEGAVPLCGGIAIFLSFFLTASLVKDGAGHADALVMMP
GLTIILGTGVLDDRFRLPVTPRFAIQLFAAVLIIAMAGVQQVFLDLNPSFIDDSGNIFAFERLGGPFLLLFAVAFIVGLV
NAVNMSDGVDGLAGSASAASFFWLAVISFDIGEHRLGLQSLALVAACLGFLVFNMRHRWRAKASLFLGDGGSTLLGAALA
GMVLILSSGRQAIAFPVLLWIVIVPVLDTLSLIVRRLAARRSPFSADRQHLHHLLMDAGLTCGQTAIIVMALNLIAGATA
YTAIRLDLPGWLMALALLAPAMAHLAFILRCTRGPRIADPAQAAKPNITFPGTTT

Sequences:

>Translated_375_residues
MTSLSWITLLAFVLSVAFSFCIAFRGLAREWYLIDLPDYRKRHEGAVPLCGGIAIFLSFFLTASLVKDGAGHADALVMMP
GLTIILGTGVLDDRFRLPVTPRFAIQLFAAVLIIAMAGVQQVFLDLNPSFIDDSGNIFAFERLGGPFLLLFAVAFIVGLV
NAVNMSDGVDGLAGSASAASFFWLAVISFDIGEHRLGLQSLALVAACLGFLVFNMRHRWRAKASLFLGDGGSTLLGAALA
GMVLILSSGRQAIAFPVLLWIVIVPVLDTLSLIVRRLAARRSPFSADRQHLHHLLMDAGLTCGQTAIIVMALNLIAGATA
YTAIRLDLPGWLMALALLAPAMAHLAFILRCTRGPRIADPAQAAKPNITFPGTTT
>Mature_374_residues
TSLSWITLLAFVLSVAFSFCIAFRGLAREWYLIDLPDYRKRHEGAVPLCGGIAIFLSFFLTASLVKDGAGHADALVMMPG
LTIILGTGVLDDRFRLPVTPRFAIQLFAAVLIIAMAGVQQVFLDLNPSFIDDSGNIFAFERLGGPFLLLFAVAFIVGLVN
AVNMSDGVDGLAGSASAASFFWLAVISFDIGEHRLGLQSLALVAACLGFLVFNMRHRWRAKASLFLGDGGSTLLGAALAG
MVLILSSGRQAIAFPVLLWIVIVPVLDTLSLIVRRLAARRSPFSADRQHLHHLLMDAGLTCGQTAIIVMALNLIAGATAY
TAIRLDLPGWLMALALLAPAMAHLAFILRCTRGPRIADPAQAAKPNITFPGTTT

Specific function: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55). It is the first lipid-linked intermediate involved in enterobacter

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. WecA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=287, Percent_Identity=35.8885017421603, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012750
- InterPro:   IPR000715 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 40104; Mature: 39973

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLSWITLLAFVLSVAFSFCIAFRGLAREWYLIDLPDYRKRHEGAVPLCGGIAIFLSFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHH
LTASLVKDGAGHADALVMMPGLTIILGTGVLDDRFRLPVTPRFAIQLFAAVLIIAMAGVQ
HHHHHHHCCCCCCCHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QVFLDLNPSFIDDSGNIFAFERLGGPFLLLFAVAFIVGLVNAVNMSDGVDGLAGSASAAS
HHHHHCCCCEECCCCCEEEEHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
FFWLAVISFDIGEHRLGLQSLALVAACLGFLVFNMRHRWRAKASLFLGDGGSTLLGAALA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHH
GMVLILSSGRQAIAFPVLLWIVIVPVLDTLSLIVRRLAARRSPFSADRQHLHHLLMDAGL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
TCGQTAIIVMALNLIAGATAYTAIRLDLPGWLMALALLAPAMAHLAFILRCTRGPRIADP
CCCHHHHHHHHHHHHHCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AQAAKPNITFPGTTT
HHHCCCCCCCCCCCC
>Mature Secondary Structure 
TSLSWITLLAFVLSVAFSFCIAFRGLAREWYLIDLPDYRKRHEGAVPLCGGIAIFLSFF
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHH
LTASLVKDGAGHADALVMMPGLTIILGTGVLDDRFRLPVTPRFAIQLFAAVLIIAMAGVQ
HHHHHHHCCCCCCCHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QVFLDLNPSFIDDSGNIFAFERLGGPFLLLFAVAFIVGLVNAVNMSDGVDGLAGSASAAS
HHHHHCCCCEECCCCCEEEEHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
FFWLAVISFDIGEHRLGLQSLALVAACLGFLVFNMRHRWRAKASLFLGDGGSTLLGAALA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHH
GMVLILSSGRQAIAFPVLLWIVIVPVLDTLSLIVRRLAARRSPFSADRQHLHHLLMDAGL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
TCGQTAIIVMALNLIAGATAYTAIRLDLPGWLMALALLAPAMAHLAFILRCTRGPRIADP
CCCHHHHHHHHHHHHHCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AQAAKPNITFPGTTT
HHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]