BacMap

Definition	Acholeplasma laidlawii PG-8A chromosome, complete genome.
Accession	NC_010163
Length	1,496,992

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The map label for this gene is ftsH

Identifier: 162448221

GI number: 162448221

Start: 1447181

End: 1449106

Strand: Direct

Name: ftsH

Synonym: ACL_1386

Alternate gene names: 162448221

Gene position: 1447181-1449106 (Clockwise)

Preceding gene: 162448220

Following gene: 162448222

Centisome position: 96.67

GC content: 36.5

Gene sequence:

>1926_bases
ATGAATAAACAACAAAAACCTAAAAGAAGCCCGCTTCGTCCGGACTATCTTGTAATTGTAATTATTATACTTTTAGCAAT
TGGTATGTACTTCTTCTTTACAGAGATGATGGCACCAAAAGTTAAACAGTTTGACGAATTTGAATTTATAGCAGCAATCG
AATCAGGACAGATTGCAACTGTACGAAGTGAATATGTCGGTGGAGATAACTTTAACCTATGGGAAGTTACCGGTACATTT
ACAACAGGTAACGCTCCAGAAGGTGTCGGAAGTTATGTCATTATACTTTATGGTGATAGGTTAAACAACATCCAAGACAT
CATCATTACTTATAATGAGTTAAACCCAAGTACACCAATCACAGTATCATTTGTTCCACACGTAAGTGTTGATTTCTGGA
ATATTATCTCAACCCTTCTCTTGATTGCAGCACCTATTGTTTTAGTCGTTATTATGTTTAGATCGATGAGTTCTCAATCT
AATAAAGCTCAAGATTTTACAAAAAACCGTGCCAAATTATCTCAAGGTAGAAAAGTTAAGTTTTCTGACATTGCTGGTGC
TGATGAAGAAAAAGCTGAAATGGCTGAATTAATCGACTTCTTAAAAAATCCTAAGAAATATGCTGATATGGGTGCTCGTG
TACCAAAGGGTGTCTTATTAGTAGGTCAACCTGGTACAGGTAAAACCTTATTAGCTAAAGCAGTTGCTGGTGAAGCACAA
GTACCATTCTTCTCAATTTCAGGTTCTGATTTCGTTGAACTTTATGTTGGGGTTGGTGCAAGCCGTGTTAGAGATTTATT
TAAAGTTGCAAAACAAAGTGCACCTTGTATTATATTTATTGATGAAATCGATGCTGTAGGTCGCCAACGTGGTGCTGGTA
TGGGTGGCGGAAATGATGAAAGAGAACAAACATTAAACCAACTACTTGTTGAAATGGATGGTTTTAGTGCAAACTTAGGT
ATCATCATTATGGCTGCAACAAACAGACCAGACGTATTAGACCCTGCATTATTAAGACCAGGCCGTTTTGATAGACAAAT
TACAATGCAAGTACCTGATCAAAAATCACGTGAAGAAATCTTAAAAGTTCATGCACGTAGTAAAAAATTAGATCCTACGA
TTAAATTTAGTGAAGTTGCAATGCGTATCCCAGGATTTACTGGTGCTGATATTGAAAACTTACTAAACGAAGCAGCATTA
TTAGCAGCAAGAGAATCTAGAACAGTCATTTCAATGCAAGACATTGATGAGGCAGCTGACCGTGTAACTATGGGACCTGC
TAAGAAATCTAGAAAATACTCACCAAATGAAAAGAAAATGGTTGCCTACCATGAAGCCGGTCATGCGGTTATTGGATTAA
AGGTTAACTTAGCTTCTACTGTTCAAAAAGTAACAATTGTCCCACGAGGACGTGCTGGTGGTTATGCACTTTATACACCA
GTTGAAGAAAAATTCAACTATGCTAAAAGTGAGTTACTAGCAATGATTACTTCTGCCTTAGGTGGACGTGTTGCTGAAGA
AATTATGTTTGATGATGTTACAACCGGAGCATATGATGACTTTAAACGTGCAACCAAGTTAGCACGTAGTATGGTTACAG
AATACGGTATGTCTGATCTTGGACCTATCCAATATGAATCAGATAGTGGAAACGTCTTCTTAGGTAGAGATTACTTAAAA
GATAAAAACTTCTCTGATGCAGTTGCACTTGAAATCGATAGAGAAGTTCGTGCAATTATTACTGAGTGTTACGAACATGC
TAGAAAAGTCATTAATGAAAATAAAAATTTACTAGATAATATCGCTAAATACTTAATCGCTGTAGAAACACTTACTAAAA
CTGATATTGATGAAATAGCAGCTACTGGACAACTTCAATGGTGGGATAACCGTGAAGTTGAAGAAGATTCTAAGAAAAGC
GAATAA

Upstream 100 bases:

>100_bases
TGTTGTGGGATATGGACTAGACTACAATGAATATTATAGAAACTTACCATACATCGGGGTATTAAAACCCGAAGTATATA
CAAAATAGGAAGGAAACAAT

Downstream 100 bases:

>100_bases
ATACTTTGAGAATCGATAAATTTTTAAAAGTATCACGCTTAATTAAACGACGTAGCGTGGCTAAAGATGTTGCAGATGCT
GATCGTATTTATGTAAATGG

Product: mebrane-bound ATP-dependent metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 641

Protein sequence:

>641_residues
MNKQQKPKRSPLRPDYLVIVIIILLAIGMYFFFTEMMAPKVKQFDEFEFIAAIESGQIATVRSEYVGGDNFNLWEVTGTF
TTGNAPEGVGSYVIILYGDRLNNIQDIIITYNELNPSTPITVSFVPHVSVDFWNIISTLLLIAAPIVLVVIMFRSMSSQS
NKAQDFTKNRAKLSQGRKVKFSDIAGADEEKAEMAELIDFLKNPKKYADMGARVPKGVLLVGQPGTGKTLLAKAVAGEAQ
VPFFSISGSDFVELYVGVGASRVRDLFKVAKQSAPCIIFIDEIDAVGRQRGAGMGGGNDEREQTLNQLLVEMDGFSANLG
IIIMAATNRPDVLDPALLRPGRFDRQITMQVPDQKSREEILKVHARSKKLDPTIKFSEVAMRIPGFTGADIENLLNEAAL
LAARESRTVISMQDIDEAADRVTMGPAKKSRKYSPNEKKMVAYHEAGHAVIGLKVNLASTVQKVTIVPRGRAGGYALYTP
VEEKFNYAKSELLAMITSALGGRVAEEIMFDDVTTGAYDDFKRATKLARSMVTEYGMSDLGPIQYESDSGNVFLGRDYLK
DKNFSDAVALEIDREVRAIITECYEHARKVINENKNLLDNIAKYLIAVETLTKTDIDEIAATGQLQWWDNREVEEDSKKS
E

Sequences:

>Translated_641_residues
MNKQQKPKRSPLRPDYLVIVIIILLAIGMYFFFTEMMAPKVKQFDEFEFIAAIESGQIATVRSEYVGGDNFNLWEVTGTF
TTGNAPEGVGSYVIILYGDRLNNIQDIIITYNELNPSTPITVSFVPHVSVDFWNIISTLLLIAAPIVLVVIMFRSMSSQS
NKAQDFTKNRAKLSQGRKVKFSDIAGADEEKAEMAELIDFLKNPKKYADMGARVPKGVLLVGQPGTGKTLLAKAVAGEAQ
VPFFSISGSDFVELYVGVGASRVRDLFKVAKQSAPCIIFIDEIDAVGRQRGAGMGGGNDEREQTLNQLLVEMDGFSANLG
IIIMAATNRPDVLDPALLRPGRFDRQITMQVPDQKSREEILKVHARSKKLDPTIKFSEVAMRIPGFTGADIENLLNEAAL
LAARESRTVISMQDIDEAADRVTMGPAKKSRKYSPNEKKMVAYHEAGHAVIGLKVNLASTVQKVTIVPRGRAGGYALYTP
VEEKFNYAKSELLAMITSALGGRVAEEIMFDDVTTGAYDDFKRATKLARSMVTEYGMSDLGPIQYESDSGNVFLGRDYLK
DKNFSDAVALEIDREVRAIITECYEHARKVINENKNLLDNIAKYLIAVETLTKTDIDEIAATGQLQWWDNREVEEDSKKS
E
>Mature_641_residues
MNKQQKPKRSPLRPDYLVIVIIILLAIGMYFFFTEMMAPKVKQFDEFEFIAAIESGQIATVRSEYVGGDNFNLWEVTGTF
TTGNAPEGVGSYVIILYGDRLNNIQDIIITYNELNPSTPITVSFVPHVSVDFWNIISTLLLIAAPIVLVVIMFRSMSSQS
NKAQDFTKNRAKLSQGRKVKFSDIAGADEEKAEMAELIDFLKNPKKYADMGARVPKGVLLVGQPGTGKTLLAKAVAGEAQ
VPFFSISGSDFVELYVGVGASRVRDLFKVAKQSAPCIIFIDEIDAVGRQRGAGMGGGNDEREQTLNQLLVEMDGFSANLG
IIIMAATNRPDVLDPALLRPGRFDRQITMQVPDQKSREEILKVHARSKKLDPTIKFSEVAMRIPGFTGADIENLLNEAAL
LAARESRTVISMQDIDEAADRVTMGPAKKSRKYSPNEKKMVAYHEAGHAVIGLKVNLASTVQKVTIVPRGRAGGYALYTP
VEEKFNYAKSELLAMITSALGGRVAEEIMFDDVTTGAYDDFKRATKLARSMVTEYGMSDLGPIQYESDSGNVFLGRDYLK
DKNFSDAVALEIDREVRAIITECYEHARKVINENKNLLDNIAKYLIAVETLTKTDIDEIAATGQLQWWDNREVEEDSKKS
E

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein; Cytoplasmic side

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family

Homologues:

Organism=Homo sapiens, GI300192933, Length=446, Percent_Identity=50.2242152466368, Blast_Score=445, Evalue=1e-125,
Organism=Homo sapiens, GI4507173, Length=503, Percent_Identity=41.948310139165, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI21327685, Length=445, Percent_Identity=44.2696629213483, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI7657689, Length=446, Percent_Identity=44.3946188340807, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI4506209, Length=253, Percent_Identity=42.2924901185771, Blast_Score=212, Evalue=9e-55,
Organism=Homo sapiens, GI24497435, Length=251, Percent_Identity=41.8326693227092, Blast_Score=209, Evalue=8e-54,
Organism=Homo sapiens, GI24430151, Length=252, Percent_Identity=39.6825396825397, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI21361144, Length=236, Percent_Identity=41.1016949152542, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI5729991, Length=245, Percent_Identity=40.4081632653061, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI89064750, Length=245, Percent_Identity=40.4081632653061, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI24430155, Length=245, Percent_Identity=40.4081632653061, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI195539395, Length=245, Percent_Identity=40.8163265306122, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI6005942, Length=258, Percent_Identity=39.922480620155, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI45643125, Length=254, Percent_Identity=39.7637795275591, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI45643123, Length=254, Percent_Identity=39.7637795275591, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI40806173, Length=195, Percent_Identity=48.2051282051282, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI157671927, Length=228, Percent_Identity=41.6666666666667, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI4505725, Length=234, Percent_Identity=39.7435897435897, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI229577436, Length=250, Percent_Identity=38.4, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI24497618, Length=233, Percent_Identity=38.6266094420601, Blast_Score=156, Evalue=6e-38,
Organism=Homo sapiens, GI194018488, Length=262, Percent_Identity=38.1679389312977, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI14149767, Length=261, Percent_Identity=37.9310344827586, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI62177112, Length=261, Percent_Identity=37.9310344827586, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI153792536, Length=237, Percent_Identity=37.5527426160338, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI5901990, Length=247, Percent_Identity=37.246963562753, Blast_Score=143, Evalue=6e-34,
Organism=Homo sapiens, GI226371754, Length=237, Percent_Identity=35.4430379746835, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI11875211, Length=235, Percent_Identity=37.8723404255319, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI40806170, Length=235, Percent_Identity=37.8723404255319, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI17865802, Length=243, Percent_Identity=35.3909465020576, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI31377644, Length=246, Percent_Identity=35.3658536585366, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI7019569, Length=243, Percent_Identity=32.5102880658436, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI31742536, Length=241, Percent_Identity=33.195020746888, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI112789543, Length=241, Percent_Identity=33.195020746888, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI156564401, Length=212, Percent_Identity=35.377358490566, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI310125280, Length=209, Percent_Identity=36.3636363636364, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI310125282, Length=212, Percent_Identity=36.3207547169811, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI64084766, Length=236, Percent_Identity=28.8135593220339, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI116292174, Length=250, Percent_Identity=25.6, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI4757852, Length=151, Percent_Identity=33.112582781457, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI119964730, Length=151, Percent_Identity=33.112582781457, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789568, Length=498, Percent_Identity=51.2048192771084, Blast_Score=512, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI71994521, Length=447, Percent_Identity=48.7695749440716, Blast_Score=416, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI115534323, Length=455, Percent_Identity=44.8351648351648, Blast_Score=368, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17554264, Length=441, Percent_Identity=45.8049886621315, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17554786, Length=248, Percent_Identity=43.5483870967742, Blast_Score=221, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI25144281, Length=248, Percent_Identity=43.1451612903226, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI25144278, Length=251, Percent_Identity=42.6294820717131, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17563248, Length=253, Percent_Identity=42.2924901185771, Blast_Score=210, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17563250, Length=252, Percent_Identity=41.6666666666667, Blast_Score=210, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17505546, Length=254, Percent_Identity=40.9448818897638, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17532375, Length=227, Percent_Identity=41.4096916299559, Blast_Score=196, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17508701, Length=240, Percent_Identity=40, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI71987364, Length=252, Percent_Identity=40.4761904761905, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71987372, Length=252, Percent_Identity=40.4761904761905, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17531535, Length=228, Percent_Identity=42.5438596491228, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17554784, Length=245, Percent_Identity=39.1836734693878, Blast_Score=178, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17508053, Length=244, Percent_Identity=38.9344262295082, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17537217, Length=282, Percent_Identity=36.5248226950355, Blast_Score=164, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI25153574, Length=226, Percent_Identity=36.7256637168142, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI193209502, Length=226, Percent_Identity=36.7256637168142, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=46.0606060606061, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=46.0606060606061, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17562804, Length=243, Percent_Identity=35.3909465020576, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI25146157, Length=244, Percent_Identity=38.9344262295082, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI193206114, Length=248, Percent_Identity=34.2741935483871, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI133931034, Length=248, Percent_Identity=34.2741935483871, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI193206116, Length=248, Percent_Identity=34.2741935483871, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI133901662, Length=209, Percent_Identity=37.3205741626794, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI133901658, Length=209, Percent_Identity=37.3205741626794, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI86561515, Length=242, Percent_Identity=34.297520661157, Blast_Score=125, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17541226, Length=271, Percent_Identity=34.3173431734317, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17541224, Length=271, Percent_Identity=34.3173431734317, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17560432, Length=277, Percent_Identity=31.0469314079422, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32563584, Length=194, Percent_Identity=38.1443298969072, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17508421, Length=194, Percent_Identity=38.1443298969072, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71990294, Length=198, Percent_Identity=28.7878787878788, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320854, Length=632, Percent_Identity=40.6645569620253, Blast_Score=432, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6323736, Length=494, Percent_Identity=46.5587044534413, Blast_Score=424, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6325281, Length=455, Percent_Identity=43.0769230769231, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6321390, Length=240, Percent_Identity=42.9166666666667, Blast_Score=209, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6322704, Length=263, Percent_Identity=39.5437262357414, Blast_Score=207, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6324691, Length=255, Percent_Identity=41.5686274509804, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6320197, Length=252, Percent_Identity=40.0793650793651, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324833, Length=256, Percent_Identity=43.359375, Blast_Score=194, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6320077, Length=238, Percent_Identity=38.655462184874, Blast_Score=192, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6320602, Length=242, Percent_Identity=40.495867768595, Blast_Score=185, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6324000, Length=267, Percent_Identity=38.9513108614232, Blast_Score=173, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6322994, Length=227, Percent_Identity=42.7312775330396, Blast_Score=170, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6323429, Length=238, Percent_Identity=40.7563025210084, Blast_Score=167, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6322651, Length=242, Percent_Identity=35.5371900826446, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6321709, Length=261, Percent_Identity=36.0153256704981, Blast_Score=151, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6325431, Length=287, Percent_Identity=32.404181184669, Blast_Score=130, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6319554, Length=217, Percent_Identity=34.5622119815668, Blast_Score=126, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6321465, Length=231, Percent_Identity=35.9307359307359, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320887, Length=260, Percent_Identity=32.6923076923077, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6325183, Length=256, Percent_Identity=32.8125, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320583, Length=156, Percent_Identity=30.1282051282051, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24665814, Length=518, Percent_Identity=44.2084942084942, Blast_Score=424, Evalue=1e-118,
Organism=Drosophila melanogaster, GI28574878, Length=518, Percent_Identity=44.2084942084942, Blast_Score=423, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24639391, Length=452, Percent_Identity=47.5663716814159, Blast_Score=405, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24658770, Length=449, Percent_Identity=45.2115812917595, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI17137738, Length=253, Percent_Identity=43.0830039525692, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI19920408, Length=251, Percent_Identity=41.0358565737052, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI45554047, Length=168, Percent_Identity=59.5238095238095, Blast_Score=209, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24651451, Length=251, Percent_Identity=41.4342629482072, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24649446, Length=252, Percent_Identity=41.2698412698413, Blast_Score=207, Evalue=3e-53,
Organism=Drosophila melanogaster, GI161076486, Length=227, Percent_Identity=40.5286343612335, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI161076488, Length=227, Percent_Identity=40.5286343612335, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI17137560, Length=227, Percent_Identity=40.5286343612335, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI17738151, Length=240, Percent_Identity=40, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI281361487, Length=241, Percent_Identity=40.2489626556017, Blast_Score=192, Evalue=8e-49,
Organism=Drosophila melanogaster, GI24640100, Length=246, Percent_Identity=41.0569105691057, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI18860063, Length=241, Percent_Identity=39.8340248962656, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24663015, Length=259, Percent_Identity=39.3822393822394, Blast_Score=187, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24660075, Length=210, Percent_Identity=44.7619047619048, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI281365776, Length=210, Percent_Identity=44.7619047619048, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI45552965, Length=210, Percent_Identity=44.7619047619048, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24652279, Length=191, Percent_Identity=42.9319371727749, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI19921202, Length=283, Percent_Identity=35.6890459363958, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24656820, Length=275, Percent_Identity=37.0909090909091, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24656825, Length=275, Percent_Identity=37.0909090909091, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI281363136, Length=237, Percent_Identity=39.662447257384, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI78707192, Length=237, Percent_Identity=39.662447257384, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21355121, Length=214, Percent_Identity=36.4485981308411, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24644145, Length=244, Percent_Identity=36.8852459016393, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI281360136, Length=241, Percent_Identity=36.0995850622407, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24644411, Length=241, Percent_Identity=36.0995850622407, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI281360144, Length=241, Percent_Identity=36.0995850622407, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI281360140, Length=241, Percent_Identity=36.0995850622407, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI281360146, Length=241, Percent_Identity=36.0995850622407, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI281360138, Length=241, Percent_Identity=36.0995850622407, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI281360142, Length=241, Percent_Identity=36.0995850622407, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI21357333, Length=241, Percent_Identity=36.0995850622407, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI18859657, Length=243, Percent_Identity=36.2139917695473, Blast_Score=139, Evalue=8e-33,
Organism=Drosophila melanogaster, GI28571849, Length=236, Percent_Identity=38.5593220338983, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI28571847, Length=236, Percent_Identity=38.5593220338983, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24581396, Length=237, Percent_Identity=36.7088607594937, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI20129529, Length=233, Percent_Identity=34.3347639484979, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI20129423, Length=262, Percent_Identity=32.4427480916031, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17864540, Length=237, Percent_Identity=33.3333333333333, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28573010, Length=209, Percent_Identity=33.4928229665072, Blast_Score=118, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24639486, Length=304, Percent_Identity=29.6052631578947, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI20129417, Length=235, Percent_Identity=31.4893617021277, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24583262, Length=235, Percent_Identity=31.4893617021277, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSH_ACHLI (A9NE17)

Other databases:

- EMBL:   CP000896
- RefSeq:   YP_001621353.1
- ProteinModelPortal:   A9NE17
- GeneID:   5803761
- GenomeReviews:   CP000896_GR
- KEGG:   acl:ACL_1386
- HOGENOM:   HBG724153
- OMA:   ERITATH
- BioCyc:   ALAI441768:ACL_1386-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01458
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR000642
- SMART:   SM00382
- TIGRFAMs:   TIGR01241

Pfam domain/function: PF00004 AAA; PF01434 Peptidase_M41

EC number: 3.4.24.-

Molecular weight: Translated: 70956; Mature: 70956

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00674 AAA

Important sites: ACT_SITE 445-445

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0x203dedd4)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQQKPKRSPLRPDYLVIVIIILLAIGMYFFFTEMMAPKVKQFDEFEFIAAIESGQIAT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEE
VRSEYVGGDNFNLWEVTGTFTTGNAPEGVGSYVIILYGDRLNNIQDIIITYNELNPSTPI
EHHHHCCCCCCEEEEEEEEEECCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCE
TVSFVPHVSVDFWNIISTLLLIAAPIVLVVIMFRSMSSQSNKAQDFTKNRAKLSQGRKVK
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEE
FSDIAGADEEKAEMAELIDFLKNPKKYADMGARVPKGVLLVGQPGTGKTLLAKAVAGEAQ
ECCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCC
VPFFSISGSDFVELYVGVGASRVRDLFKVAKQSAPCIIFIDEIDAVGRQRGAGMGGGNDE
CCEEEECCCCEEHHEECCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHCCCCCCCCCHH
REQTLNQLLVEMDGFSANLGIIIMAATNRPDVLDPALLRPGRFDRQITMQVPDQKSREEI
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCEEEEECCCCCHHHHH
LKVHARSKKLDPTIKFSEVAMRIPGFTGADIENLLNEAALLAARESRTVISMQDIDEAAD
HHHHHHCCCCCCCEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHH
RVTMGPAKKSRKYSPNEKKMVAYHEAGHAVIGLKVNLASTVQKVTIVPRGRAGGYALYTP
HCCCCCCHHCCCCCCCCCCEEEEECCCCEEEEEEEEHHHHCEEEEEEECCCCCCEEEECC
VEEKFNYAKSELLAMITSALGGRVAEEIMFDDVTTGAYDDFKRATKLARSMVTEYGMSDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GPIQYESDSGNVFLGRDYLKDKNFSDAVALEIDREVRAIITECYEHARKVINENKNLLDN
CCEEEECCCCCEEECHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCHHHHHH
IAKYLIAVETLTKTDIDEIAATGQLQWWDNREVEEDSKKSE
HHHHHHHHHHHHHCCHHHHHCCCCEEECCCCCCCCHHCCCH
>Mature Secondary Structure
MNKQQKPKRSPLRPDYLVIVIIILLAIGMYFFFTEMMAPKVKQFDEFEFIAAIESGQIAT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEE
VRSEYVGGDNFNLWEVTGTFTTGNAPEGVGSYVIILYGDRLNNIQDIIITYNELNPSTPI
EHHHHCCCCCCEEEEEEEEEECCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCE
TVSFVPHVSVDFWNIISTLLLIAAPIVLVVIMFRSMSSQSNKAQDFTKNRAKLSQGRKVK
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEE
FSDIAGADEEKAEMAELIDFLKNPKKYADMGARVPKGVLLVGQPGTGKTLLAKAVAGEAQ
ECCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCC
VPFFSISGSDFVELYVGVGASRVRDLFKVAKQSAPCIIFIDEIDAVGRQRGAGMGGGNDE
CCEEEECCCCEEHHEECCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHCCCCCCCCCHH
REQTLNQLLVEMDGFSANLGIIIMAATNRPDVLDPALLRPGRFDRQITMQVPDQKSREEI
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCEEEEECCCCCHHHHH
LKVHARSKKLDPTIKFSEVAMRIPGFTGADIENLLNEAALLAARESRTVISMQDIDEAAD
HHHHHHCCCCCCCEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHH
RVTMGPAKKSRKYSPNEKKMVAYHEAGHAVIGLKVNLASTVQKVTIVPRGRAGGYALYTP
HCCCCCCHHCCCCCCCCCCEEEEECCCCEEEEEEEEHHHHCEEEEEEECCCCCCEEEECC
VEEKFNYAKSELLAMITSALGGRVAEEIMFDDVTTGAYDDFKRATKLARSMVTEYGMSDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GPIQYESDSGNVFLGRDYLKDKNFSDAVALEIDREVRAIITECYEHARKVINENKNLLDN
CCEEEECCCCCEEECHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCHHHHHH
IAKYLIAVETLTKTDIDEIAATGQLQWWDNREVEEDSKKSE
HHHHHHHHHHHHHCCHHHHHCCCCEEECCCCCCCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA