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The map label for this gene is rnhC [H]

Identifier: 162447673

GI number: 162447673

Start: 851580

End: 852437

Strand: Direct

Name: rnhC [H]

Synonym: ACL_0815

Alternate gene names: 162447673

Gene position: 851580-852437 (Clockwise)

Preceding gene: 162447664

Following gene: 162447688

Centisome position: 56.89

GC content: 31.35

Gene sequence:

>858_bases
TTGAGAAATTATACAATTAGCTTATCTAGCGACCAGCTAGTTTTGCTTAAACAATTTTATAGCAATTATTTATTAAAAGT
GGAGCAGCCATATGTTTTTTTTGTTGCTCATCATAATGATACACGTATTAGTGCATTTAAATCAGGTAAAGTTGTACTTC
AAGGTGAAGAAATTAATCCTGAATTAGTAGCAATTAAATCTTTTTTAAATATAACTAATTATGCTGCAATCGGTTCTGAT
GAAGTTGGTACAGGTGATGCTTTAGGTCCAGTGGTTGTATGTAGTGCATATGCCTCTATTGAAGATATCGAATTCCTAGA
AAAACTAGGTGTTAAAGATTCTAAATCTATGACTAATAAAGAAATCGTTAAACTAGGTCCTGTCATTGCAAATCGATTAA
CACACTCTATTGTGATATTAACCCCCGAGAAGTTTAATGAACAAACTCAGAAGGGTTTGAACTTAAACAAAATTAAAGCG
CTCTTACATAATCATATGATTATTAAGACAACTTCAAAAGTTGAAGCTGCAGTGCCTGTAATTTTAGATCAATTTTGTTT
ACCAACACATTACTTTAACTACCTAAAGGATGAAAAGTTAGTGTACCGTGATGTTGAGTTTTACACCAAAGCAGAGTCTG
TACATTTAAGTGTAGCTGCTGCTTCAATTATTGCACGTTATGCATTCTTAGTTAAAATGCATCAATACTCCAAGAAATTA
AATATGAAATTAAAACTTGGTGCTAGTAAAGAAGTCGATGTTCAAATTAAAGAAATATATGACACGCATGGTTTAGATGG
GCTAAATAAAATAGCCAAGATGAACTTTAAGAATGTCACAAAACAAAATTTAACCTAA

Upstream 100 bases:

>100_bases
TCTAATATTAAATTAAATTCTAATGCTTTTGTCGAATACATTTAAAAACTCCTTATTTCACACTTTTTATGGTATAATAT
GACTCAGTAGGTGAAGATTA

Downstream 100 bases:

>100_bases
GGTAACTAGATAACTTTCAAATTCAGGTGGTAATGGTGCTTCAAGCATCATTACTTTTTTTGTTATTGGATGCACAAATT
CTAATCTAAATGCATGTAAT

Product: ribonuclease HIII

Products: NA

Alternate protein names: RNase HIII [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MRNYTISLSSDQLVLLKQFYSNYLLKVEQPYVFFVAHHNDTRISAFKSGKVVLQGEEINPELVAIKSFLNITNYAAIGSD
EVGTGDALGPVVVCSAYASIEDIEFLEKLGVKDSKSMTNKEIVKLGPVIANRLTHSIVILTPEKFNEQTQKGLNLNKIKA
LLHNHMIIKTTSKVEAAVPVILDQFCLPTHYFNYLKDEKLVYRDVEFYTKAESVHLSVAAASIIARYAFLVKMHQYSKKL
NMKLKLGASKEVDVQIKEIYDTHGLDGLNKIAKMNFKNVTKQNLT

Sequences:

>Translated_285_residues
MRNYTISLSSDQLVLLKQFYSNYLLKVEQPYVFFVAHHNDTRISAFKSGKVVLQGEEINPELVAIKSFLNITNYAAIGSD
EVGTGDALGPVVVCSAYASIEDIEFLEKLGVKDSKSMTNKEIVKLGPVIANRLTHSIVILTPEKFNEQTQKGLNLNKIKA
LLHNHMIIKTTSKVEAAVPVILDQFCLPTHYFNYLKDEKLVYRDVEFYTKAESVHLSVAAASIIARYAFLVKMHQYSKKL
NMKLKLGASKEVDVQIKEIYDTHGLDGLNKIAKMNFKNVTKQNLT
>Mature_285_residues
MRNYTISLSSDQLVLLKQFYSNYLLKVEQPYVFFVAHHNDTRISAFKSGKVVLQGEEINPELVAIKSFLNITNYAAIGSD
EVGTGDALGPVVVCSAYASIEDIEFLEKLGVKDSKSMTNKEIVKLGPVIANRLTHSIVILTPEKFNEQTQKGLNLNKIKA
LLHNHMIIKTTSKVEAAVPVILDQFCLPTHYFNYLKDEKLVYRDVEFYTKAESVHLSVAAASIIARYAFLVKMHQYSKKL
NMKLKLGASKEVDVQIKEIYDTHGLDGLNKIAKMNFKNVTKQNLT

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG1039

COG function: function code L; Ribonuclease HIII

Gene ontology:
GO:0003676: Ribonuclease
GO:0003723: Ribonuclease
GO:0004518: Ribonuclease
GO:0004519: Ribonuclease
GO:0004523: Ribonuclease
GO:0005737: Ribonuclease
GO:0016070: Ribonuclease
GO:0016787: Ribonuclease
GO:0046872: Ribonuclease

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family. RnhC subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001352
- InterPro:   IPR004641
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 32090; Mature: 32090

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNYTISLSSDQLVLLKQFYSNYLLKVEQPYVFFVAHHNDTRISAFKSGKVVLQGEEINP
CCCEEEEECCCCHHHHHHHHHHHEEEECCCEEEEEEECCCCEEEEECCCEEEEECCCCCC
ELVAIKSFLNITNYAAIGSDEVGTGDALGPVVVCSAYASIEDIEFLEKLGVKDSKSMTNK
HHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCCCCCCCCHH
EIVKLGPVIANRLTHSIVILTPEKFNEQTQKGLNLNKIKALLHNHMIIKTTSKVEAAVPV
HHHHHHHHHHHHHCCEEEEECCHHHCHHHHHCCCHHHHHHHHHCCEEEEECCHHHHHHHH
ILDQFCLPTHYFNYLKDEKLVYRDVEFYTKAESVHLSVAAASIIARYAFLVKMHQYSKKL
HHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHC
NMKLKLGASKEVDVQIKEIYDTHGLDGLNKIAKMNFKNVTKQNLT
CEEEEECCCCCCCEEHHHHHHHCCCCHHHHHHHCCHHHHHHCCCC
>Mature Secondary Structure
MRNYTISLSSDQLVLLKQFYSNYLLKVEQPYVFFVAHHNDTRISAFKSGKVVLQGEEINP
CCCEEEEECCCCHHHHHHHHHHHEEEECCCEEEEEEECCCCEEEEECCCEEEEECCCCCC
ELVAIKSFLNITNYAAIGSDEVGTGDALGPVVVCSAYASIEDIEFLEKLGVKDSKSMTNK
HHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCCCCCCCCHH
EIVKLGPVIANRLTHSIVILTPEKFNEQTQKGLNLNKIKALLHNHMIIKTTSKVEAAVPV
HHHHHHHHHHHHHCCEEEEECCHHHCHHHHHCCCHHHHHHHHHCCEEEEECCHHHHHHHH
ILDQFCLPTHYFNYLKDEKLVYRDVEFYTKAESVHLSVAAASIIARYAFLVKMHQYSKKL
HHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHC
NMKLKLGASKEVDVQIKEIYDTHGLDGLNKIAKMNFKNVTKQNLT
CEEEEECCCCCCCEEHHHHHHHCCCCHHHHHHHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA