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The map label for this gene is gpo [H]

Identifier: 162447530

GI number: 162447530

Start: 702768

End: 703280

Strand: Direct

Name: gpo [H]

Synonym: ACL_0670

Alternate gene names: 162447530

Gene position: 702768-703280 (Clockwise)

Preceding gene: 162447529

Following gene: 162447531

Centisome position: 46.95

GC content: 30.41

Gene sequence:

>513_bases
ATGAGTTTATATGATATTGAAGTTACAAGAGCAGACGGTTCTAAAGAAATGATGTCAAAATATCAAGGTAAAGTCTTATT
GATTGTAAATACTGCTACAAAATGTGGTTATACAAAACAATATGAAGGTTTGCAAGAAATCTATGACAACTATAAAGATA
AGGGTTTTGAAATCCTTGATTTTCCATGTAACCAATTTTTAGCACAAGCACCGGGTTCCATCAAAAAAATCAATGAATTC
TGTCAAATTAATTTCGGAACAACATTTACACTATTTGATAAAGTGAAAGTGAATTCTAAAAATGCACATCCACTTTATAA
ATACTTAAAAGATAACGGTCCTGAAGAAGTTGTCGTATCACATGATGCATTAGTACCCTCAGGTAAACCAAAAGATAAAA
TTAGTTGGAATTTTACTAAATTTTTAATTAGTAAAGAAGGTGAGATATTGTACCGTTTTTCACCGAAAGTTACGCCTGAA
GAGTTACTACCTTATCTACAAAAAACACTGTAA

Upstream 100 bases:

>100_bases
CGTAAAAGATTAAAGAAAACTATAAATACAGAAGAAATCTAGCAAGAAGGTTTCTTCTGTTTTTTTACCAACAATAAAAT
AAATAAAGAGGAGAAGTGCG

Downstream 100 bases:

>100_bases
TAACTGTGTGTAGATTATGATAATCATTGACTTTCAGGGCTATTTTTGATATGATTATATCGTTATTAAAATGTAATAAC
ACGGAGGAAGTACATAAATA

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MSLYDIEVTRADGSKEMMSKYQGKVLLIVNTATKCGYTKQYEGLQEIYDNYKDKGFEILDFPCNQFLAQAPGSIKKINEF
CQINFGTTFTLFDKVKVNSKNAHPLYKYLKDNGPEEVVVSHDALVPSGKPKDKISWNFTKFLISKEGEILYRFSPKVTPE
ELLPYLQKTL

Sequences:

>Translated_170_residues
MSLYDIEVTRADGSKEMMSKYQGKVLLIVNTATKCGYTKQYEGLQEIYDNYKDKGFEILDFPCNQFLAQAPGSIKKINEF
CQINFGTTFTLFDKVKVNSKNAHPLYKYLKDNGPEEVVVSHDALVPSGKPKDKISWNFTKFLISKEGEILYRFSPKVTPE
ELLPYLQKTL
>Mature_169_residues
SLYDIEVTRADGSKEMMSKYQGKVLLIVNTATKCGYTKQYEGLQEIYDNYKDKGFEILDFPCNQFLAQAPGSIKKINEFC
QINFGTTFTLFDKVKVNSKNAHPLYKYLKDNGPEEVVVSHDALVPSGKPKDKISWNFTKFLISKEGEILYRFSPKVTPEE
LLPYLQKTL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=165, Percent_Identity=33.9393939393939, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI90903240, Length=170, Percent_Identity=35.8823529411765, Blast_Score=104, Evalue=3e-23,
Organism=Homo sapiens, GI75709200, Length=170, Percent_Identity=35.8823529411765, Blast_Score=104, Evalue=5e-23,
Organism=Homo sapiens, GI192455698, Length=164, Percent_Identity=32.9268292682927, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI90903238, Length=143, Percent_Identity=35.6643356643357, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI4557629, Length=179, Percent_Identity=31.2849162011173, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI32967607, Length=165, Percent_Identity=32.7272727272727, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI41406084, Length=175, Percent_Identity=31.4285714285714, Blast_Score=80, Evalue=9e-16,
Organism=Homo sapiens, GI6006001, Length=179, Percent_Identity=30.1675977653631, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI33186887, Length=154, Percent_Identity=30.5194805194805, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1788003, Length=167, Percent_Identity=42.5149700598802, Blast_Score=145, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17506887, Length=170, Percent_Identity=40, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17535473, Length=170, Percent_Identity=40, Blast_Score=123, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17550320, Length=180, Percent_Identity=32.2222222222222, Blast_Score=110, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71993584, Length=170, Percent_Identity=35.2941176470588, Blast_Score=109, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI193209493, Length=163, Percent_Identity=34.3558282208589, Blast_Score=108, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI193210707, Length=174, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71999642, Length=71, Percent_Identity=43.6619718309859, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71993573, Length=96, Percent_Identity=35.4166666666667, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=169, Percent_Identity=44.3786982248521, Blast_Score=140, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6322228, Length=149, Percent_Identity=43.6241610738255, Blast_Score=128, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6322826, Length=169, Percent_Identity=35.5029585798817, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24656777, Length=172, Percent_Identity=38.3720930232558, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24656772, Length=172, Percent_Identity=38.3720930232558, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24656767, Length=172, Percent_Identity=37.7906976744186, Blast_Score=110, Evalue=4e-25,
Organism=Drosophila melanogaster, GI85726443, Length=164, Percent_Identity=34.1463414634146, Blast_Score=95, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 19485; Mature: 19353

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLYDIEVTRADGSKEMMSKYQGKVLLIVNTATKCGYTKQYEGLQEIYDNYKDKGFEILD
CCEEEEEEEECCCCHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
FPCNQFLAQAPGSIKKINEFCQINFGTTFTLFDKVKVNSKNAHPLYKYLKDNGPEEVVVS
CCHHHHHHHCCCHHHHHHHHHEECCCCEEEEEEEEEECCCCCCHHHHHHHCCCCCEEEEE
HDALVPSGKPKDKISWNFTKFLISKEGEILYRFSPKVTPEELLPYLQKTL
CCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SLYDIEVTRADGSKEMMSKYQGKVLLIVNTATKCGYTKQYEGLQEIYDNYKDKGFEILD
CEEEEEEEECCCCHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
FPCNQFLAQAPGSIKKINEFCQINFGTTFTLFDKVKVNSKNAHPLYKYLKDNGPEEVVVS
CCHHHHHHHCCCHHHHHHHHHEECCCCEEEEEEEEEECCCCCCHHHHHHHCCCCCEEEEE
HDALVPSGKPKDKISWNFTKFLISKEGEILYRFSPKVTPEELLPYLQKTL
CCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]