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The map label for this gene is ytfL [C]

Identifier: 162447531

GI number: 162447531

Start: 703448

End: 704797

Strand: Direct

Name: ytfL [C]

Synonym: ACL_0671

Alternate gene names: 162447531

Gene position: 703448-704797 (Clockwise)

Preceding gene: 162447530

Following gene: 162447533

Centisome position: 46.99

GC content: 32.74

Gene sequence:

>1350_bases
ATGGGATTACAAATATTCTTAATTGTATTTTTTATTGTCTTAAACGGTATATTTGCAGCTAGTGAAATTGCACTAGTATC
TGCAAATAGAAGAGAGATTCAAGAAGATGCTGATGCAGGTGGTAAGAAAGCTAAAAAAGCTAAACGAGTGTTAAAACTCA
TTGAGAATCCAACAAGATTCTTGTCTACTATTCAAATCGGTATTACGATGTTTGGTTTTATTAATGGGGTGATTGCAGCG
GATGCATTCTCTAATCTCATCTCAGACCAAATTGCAAATTGGACAGGGTTTGATACATTAATTATCATTCCAGTTGTCAC
ATTTATAATCACACTGATCTTAACTTATTTCCAAGTTATCTTTGGAGAGTTAGTACCTAAACGTATTGCTATGAAGTCAC
CTGAACGTGTTTCATATATATTTATTGGGTTTTTAAGTGCGATTGCAGTCATAATGAAGCCATTTGTTGTATTATTAACG
TCTTCAGCAAATCTGATCATTCGTTTATTTGGCATAAACCCGCAAGATGATGATGACACATTATCCGAAGAGGAACTCAT
CTTAGAACTAAATGCCTCAGAGTCTAAAGGGTTCATTGACAGTTCAGAAAATGAAATGATTCAAAATATATTTGAATTTG
ATTCAACAACTGTTGAAGAAGTCATGACCCACAGAACTGAAGTTTCAGCAATCAATGTAAATTCTACAAGAGACGAACTT
GTAAAATTCGTAACAAACGAAAAATACACAAGATTTCCAGTATATGAGGAAACCTTAGATAAAATCGTTGGTACACTTCA
TGTTAAAGATTTATTAAAATATCTATCAGAACATGAAGATAAAAACGAATTTGATATTCATGAAATATTAAGAGATCCAC
TCTTTGTACCTCAATCTAAAAATACAAGAGCGTTATTTAGAGAAATGAAATTAACTAAAACGCATATTGCAATTGTAATT
GATGAGTACGGTGGAACTGCTGGTATTATCACCTTTGAAGACTTAATTGAAGAGATATTAGGTAATATTTCTGATGAGTA
TGATGAGGATGAAGAAGAAATTCAAGCAATCAGTGAAGACAGATATGAAATCGATGGTTTAATTGATTTAGATGATGTCG
AAGATTTAATACATGCTGGTTTACCAATAGAGGATTATGACACTTTATCAGGGTTTTTACTTGGCCAATTAGGTCGATTC
CCGGAAGCTGATGAATCCATAGTTGTAGTATACGGACATTATAGATTCGAAGTTCTATCTTATGAAGATAAAATCATTGA
ACGTGTTTTGGTTACACGTATCGAAGAAGAACCAATTGAAGAAGTAATGAATGAAACGGATGCAATGTAA

Upstream 100 bases:

>100_bases
AAAATGTAATAACACGGAGGAAGTACATAAATATGGAAGATTCAAGTAGCGGGCAGAGGACAACATTAAGTGATGACCCA
CACGAGGGGGTAACCTTCTA

Downstream 100 bases:

>100_bases
TTTGCATCCGTTTTTCTTTTAATGTTTTTTAAAATATACCTAAACTCAATGACAAAGTCATAAAAAAAGGTATCCATTAA
TGGATACCTTATTTAATATA

Product: CBS-domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MGLQIFLIVFFIVLNGIFAASEIALVSANRREIQEDADAGGKKAKKAKRVLKLIENPTRFLSTIQIGITMFGFINGVIAA
DAFSNLISDQIANWTGFDTLIIIPVVTFIITLILTYFQVIFGELVPKRIAMKSPERVSYIFIGFLSAIAVIMKPFVVLLT
SSANLIIRLFGINPQDDDDTLSEEELILELNASESKGFIDSSENEMIQNIFEFDSTTVEEVMTHRTEVSAINVNSTRDEL
VKFVTNEKYTRFPVYEETLDKIVGTLHVKDLLKYLSEHEDKNEFDIHEILRDPLFVPQSKNTRALFREMKLTKTHIAIVI
DEYGGTAGIITFEDLIEEILGNISDEYDEDEEEIQAISEDRYEIDGLIDLDDVEDLIHAGLPIEDYDTLSGFLLGQLGRF
PEADESIVVVYGHYRFEVLSYEDKIIERVLVTRIEEEPIEEVMNETDAM

Sequences:

>Translated_449_residues
MGLQIFLIVFFIVLNGIFAASEIALVSANRREIQEDADAGGKKAKKAKRVLKLIENPTRFLSTIQIGITMFGFINGVIAA
DAFSNLISDQIANWTGFDTLIIIPVVTFIITLILTYFQVIFGELVPKRIAMKSPERVSYIFIGFLSAIAVIMKPFVVLLT
SSANLIIRLFGINPQDDDDTLSEEELILELNASESKGFIDSSENEMIQNIFEFDSTTVEEVMTHRTEVSAINVNSTRDEL
VKFVTNEKYTRFPVYEETLDKIVGTLHVKDLLKYLSEHEDKNEFDIHEILRDPLFVPQSKNTRALFREMKLTKTHIAIVI
DEYGGTAGIITFEDLIEEILGNISDEYDEDEEEIQAISEDRYEIDGLIDLDDVEDLIHAGLPIEDYDTLSGFLLGQLGRF
PEADESIVVVYGHYRFEVLSYEDKIIERVLVTRIEEEPIEEVMNETDAM
>Mature_448_residues
GLQIFLIVFFIVLNGIFAASEIALVSANRREIQEDADAGGKKAKKAKRVLKLIENPTRFLSTIQIGITMFGFINGVIAAD
AFSNLISDQIANWTGFDTLIIIPVVTFIITLILTYFQVIFGELVPKRIAMKSPERVSYIFIGFLSAIAVIMKPFVVLLTS
SANLIIRLFGINPQDDDDTLSEEELILELNASESKGFIDSSENEMIQNIFEFDSTTVEEVMTHRTEVSAINVNSTRDELV
KFVTNEKYTRFPVYEETLDKIVGTLHVKDLLKYLSEHEDKNEFDIHEILRDPLFVPQSKNTRALFREMKLTKTHIAIVID
EYGGTAGIITFEDLIEEILGNISDEYDEDEEEIQAISEDRYEIDGLIDLDDVEDLIHAGLPIEDYDTLSGFLLGQLGRFP
EADESIVVVYGHYRFEVLSYEDKIIERVLVTRIEEEPIEEVMNETDAM

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=386, Percent_Identity=35.7512953367876, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI40068055, Length=360, Percent_Identity=26.1111111111111, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI40068053, Length=360, Percent_Identity=26.1111111111111, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790664, Length=441, Percent_Identity=27.2108843537415, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI145693175, Length=435, Percent_Identity=26.4367816091954, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786879, Length=275, Percent_Identity=27.6363636363636, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87082033, Length=414, Percent_Identity=23.9130434782609, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788119, Length=353, Percent_Identity=24.6458923512748, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324512, Length=359, Percent_Identity=24.5125348189415, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50925; Mature: 50794

Theoretical pI: Translated: 4.10; Mature: 4.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLQIFLIVFFIVLNGIFAASEIALVSANRREIQEDADAGGKKAKKAKRVLKLIENPTRF
CCHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHH
LSTIQIGITMFGFINGVIAADAFSNLISDQIANWTGFDTLIIIPVVTFIITLILTYFQVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FGELVPKRIAMKSPERVSYIFIGFLSAIAVIMKPFVVLLTSSANLIIRLFGINPQDDDDT
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCC
LSEEELILELNASESKGFIDSSENEMIQNIFEFDSTTVEEVMTHRTEVSAINVNSTRDEL
CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCEEEECCCCHHHH
VKFVTNEKYTRFPVYEETLDKIVGTLHVKDLLKYLSEHEDKNEFDIHEILRDPLFVPQSK
HHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCC
NTRALFREMKLTKTHIAIVIDEYGGTAGIITFEDLIEEILGNISDEYDEDEEEIQAISED
CHHHHHHHHHHHHEEEEEEEECCCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
RYEIDGLIDLDDVEDLIHAGLPIEDYDTLSGFLLGQLGRFPEADESIVVVYGHYRFEVLS
CHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECEEEEEEC
YEDKIIERVLVTRIEEEPIEEVMNETDAM
HHHHHHHHHHHHHHCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GLQIFLIVFFIVLNGIFAASEIALVSANRREIQEDADAGGKKAKKAKRVLKLIENPTRF
CHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHH
LSTIQIGITMFGFINGVIAADAFSNLISDQIANWTGFDTLIIIPVVTFIITLILTYFQVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FGELVPKRIAMKSPERVSYIFIGFLSAIAVIMKPFVVLLTSSANLIIRLFGINPQDDDDT
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCC
LSEEELILELNASESKGFIDSSENEMIQNIFEFDSTTVEEVMTHRTEVSAINVNSTRDEL
CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCEEEECCCCHHHH
VKFVTNEKYTRFPVYEETLDKIVGTLHVKDLLKYLSEHEDKNEFDIHEILRDPLFVPQSK
HHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCC
NTRALFREMKLTKTHIAIVIDEYGGTAGIITFEDLIEEILGNISDEYDEDEEEIQAISED
CHHHHHHHHHHHHEEEEEEEECCCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
RYEIDGLIDLDDVEDLIHAGLPIEDYDTLSGFLLGQLGRFPEADESIVVVYGHYRFEVLS
CHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECEEEEEEC
YEDKIIERVLVTRIEEEPIEEVMNETDAM
HHHHHHHHHHHHHHCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]