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The map label for this gene is hrcA

Identifier: 162447410

GI number: 162447410

Start: 584062

End: 585090

Strand: Direct

Name: hrcA

Synonym: ACL_0548

Alternate gene names: 162447410

Gene position: 584062-585090 (Clockwise)

Preceding gene: 162447405

Following gene: 162447411

Centisome position: 39.02

GC content: 33.82

Gene sequence:

>1029_bases
ATGATATCGTCAAGACAAAAACTCATCTTAAAAGCAATCATTGATATGTATTCTGAAAAGGGTGAACCGGTAGGTTCTAA
AGCCTTAATGGCGCTTCCATACTTAAATTACTCATCAGCTACATTAAGATATGATATGGCAGTTTTAGAAGAACTAGGTT
TTCTCGAGAAGATGCATACTTCATCAGGTAGAGTACCTTCTGAACGTGGTTATCGTTACTATATTGAACATTTAGTGACA
AGGGATAATGATGTGACAGAAGTATTTCCTTTAATCGATGAAGTTTTTAGTAAAAAAGCACTTGGTCGTGAACACACGAT
TAAAGAAGCATTAAAGTTACTAACCGATCTTACAAGCTACACAGCTGTTGCAGTAGGACCAGATATCTTACAATCTCATA
TTAAGCGTATTGAAATGGTACCACTTGGTTTAAAAGATGCAGTCATGTTAATTGTAACCGACACAGGGCACGTACAACAT
CAACAAATTCATATATCAGATGATATGAGAATGGATGATATTAAGGAAGTTATACATACACTGGATGACTTACTTAAGAA
TAGAACACTAGAAGATGCACTTAAGGTACTCAAAGAGGAATATGCAATTTCTGAACTGAATCAATTTATGAGCTATCAAA
GTCAAATCATTGATTCATTCATTGAAGCATTTTCTAAATTTGCATCAGATTCCTTCTATTTAAGTGGTATGACGAATGCT
TTTGAACAACCAGAATTTAATGATGTTTCTCATATGAAACGATTTATAGATATGATGGATCGTCGTGAAATTGTGAAGTT
GATTGGAACTGCTGAAGGCATATCAGTAAGATTTGGGTCAGATATGGAAATCAAACCCTTAAATCAAATGACAATCATTT
CTATACCTTATCAAATAGATTCAAAACAAAAAGGAACGATTGCACTTGTAGGACCTTCAAGAATGTCTTATCAAAAGGTA
ATCCCCTTGTTAGAGTACATTGCAGCAAATCTAGCAAAACTATATAAAGACAATAATAAGGAGACTTAG

Upstream 100 bases:

>100_bases
AAAAAATGTAAATTTAGCACATAAATCTTGACAGTGCTATTTTTTTATTATACAATGATGTTGGCACTATGATAAAGCGA
GTGCTAAAAGGGTGGTAAGC

Downstream 100 bases:

>100_bases
AAGATGGCAGATAAAGAAAAAGATGCAGTTATCGTTGATGAAACGGAACATGTAGATGTAGATTCAAAAGAATCGAAAAA
AGAAAAGAAAACAAAACAAC

Product: transcription repressor of heat shock proteins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MISSRQKLILKAIIDMYSEKGEPVGSKALMALPYLNYSSATLRYDMAVLEELGFLEKMHTSSGRVPSERGYRYYIEHLVT
RDNDVTEVFPLIDEVFSKKALGREHTIKEALKLLTDLTSYTAVAVGPDILQSHIKRIEMVPLGLKDAVMLIVTDTGHVQH
QQIHISDDMRMDDIKEVIHTLDDLLKNRTLEDALKVLKEEYAISELNQFMSYQSQIIDSFIEAFSKFASDSFYLSGMTNA
FEQPEFNDVSHMKRFIDMMDRREIVKLIGTAEGISVRFGSDMEIKPLNQMTIISIPYQIDSKQKGTIALVGPSRMSYQKV
IPLLEYIAANLAKLYKDNNKET

Sequences:

>Translated_342_residues
MISSRQKLILKAIIDMYSEKGEPVGSKALMALPYLNYSSATLRYDMAVLEELGFLEKMHTSSGRVPSERGYRYYIEHLVT
RDNDVTEVFPLIDEVFSKKALGREHTIKEALKLLTDLTSYTAVAVGPDILQSHIKRIEMVPLGLKDAVMLIVTDTGHVQH
QQIHISDDMRMDDIKEVIHTLDDLLKNRTLEDALKVLKEEYAISELNQFMSYQSQIIDSFIEAFSKFASDSFYLSGMTNA
FEQPEFNDVSHMKRFIDMMDRREIVKLIGTAEGISVRFGSDMEIKPLNQMTIISIPYQIDSKQKGTIALVGPSRMSYQKV
IPLLEYIAANLAKLYKDNNKET
>Mature_342_residues
MISSRQKLILKAIIDMYSEKGEPVGSKALMALPYLNYSSATLRYDMAVLEELGFLEKMHTSSGRVPSERGYRYYIEHLVT
RDNDVTEVFPLIDEVFSKKALGREHTIKEALKLLTDLTSYTAVAVGPDILQSHIKRIEMVPLGLKDAVMLIVTDTGHVQH
QQIHISDDMRMDDIKEVIHTLDDLLKNRTLEDALKVLKEEYAISELNQFMSYQSQIIDSFIEAFSKFASDSFYLSGMTNA
FEQPEFNDVSHMKRFIDMMDRREIVKLIGTAEGISVRFGSDMEIKPLNQMTIISIPYQIDSKQKGTIALVGPSRMSYQKV
IPLLEYIAANLAKLYKDNNKET

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_ACHLA (Q8L3A0)

Other databases:

- EMBL:   AF281816
- ProteinModelPortal:   Q8L3A0
- SMR:   Q8L3A0
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF01628 HrcA

EC number: NA

Molecular weight: Translated: 38995; Mature: 38995

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSRQKLILKAIIDMYSEKGEPVGSKALMALPYLNYSSATLRYDMAVLEELGFLEKMHT
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
SSGRVPSERGYRYYIEHLVTRDNDVTEVFPLIDEVFSKKALGREHTIKEALKLLTDLTSY
CCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TAVAVGPDILQSHIKRIEMVPLGLKDAVMLIVTDTGHVQHQQIHISDDMRMDDIKEVIHT
HHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHH
LDDLLKNRTLEDALKVLKEEYAISELNQFMSYQSQIIDSFIEAFSKFASDSFYLSGMTNA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHH
FEQPEFNDVSHMKRFIDMMDRREIVKLIGTAEGISVRFGSDMEIKPLNQMTIISIPYQID
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEECCEEC
SKQKGTIALVGPSRMSYQKVIPLLEYIAANLAKLYKDNNKET
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MISSRQKLILKAIIDMYSEKGEPVGSKALMALPYLNYSSATLRYDMAVLEELGFLEKMHT
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
SSGRVPSERGYRYYIEHLVTRDNDVTEVFPLIDEVFSKKALGREHTIKEALKLLTDLTSY
CCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TAVAVGPDILQSHIKRIEMVPLGLKDAVMLIVTDTGHVQHQQIHISDDMRMDDIKEVIHT
HHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHH
LDDLLKNRTLEDALKVLKEEYAISELNQFMSYQSQIIDSFIEAFSKFASDSFYLSGMTNA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHH
FEQPEFNDVSHMKRFIDMMDRREIVKLIGTAEGISVRFGSDMEIKPLNQMTIISIPYQID
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEECCEEC
SKQKGTIALVGPSRMSYQKVIPLLEYIAANLAKLYKDNNKET
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA