| Definition | Acholeplasma laidlawii PG-8A chromosome, complete genome. |
|---|---|
| Accession | NC_010163 |
| Length | 1,496,992 |
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The map label for this gene is yvgN [H]
Identifier: 162447396
GI number: 162447396
Start: 568111
End: 568905
Strand: Direct
Name: yvgN [H]
Synonym: ACL_0534
Alternate gene names: 162447396
Gene position: 568111-568905 (Clockwise)
Preceding gene: 162447395
Following gene: 162447397
Centisome position: 37.95
GC content: 32.7
Gene sequence:
>795_bases ATGGAATATTTAACACTTCATAATGGTTTTAAAGTACCAGTTGTAGGTATGGGTGCAAACACATTTGGTAAAGTGAATCA TGATTTTTATGGTGCACTTGATAATGACACTAAAGAACTAATTTGGGCATATGAAAATGGCTACCGCCTCATAGATACAG CAATCGTTTATAGAAATGAAACAGTGATTGCCAAATCAATTAAAGATGCCCATCTAAATAGAAAAGATGTCATGGTTACA TCTAAAATACCTACCAAAGAATTACCACTAGAAGATGATGAAAAAATTGAGGCGATGATACAATCGTCCATCAATATATT TGGAGGTTATGTAGATATCTATTTAATTCATCATCCATCCACGGATGAAATTAATTTAAAGGTCTGGAAAGCACTTGAAA GTCATTATCTAAAAGGACACTTTAAAGCAATTGGTGTATCCAATTTTAGTAAGGAGCAACTTGATTACATCATGAAGTAT GCAAATATTAAACCCATGATGAATCAAATAGAATCTAATCCAGCAAACTGGCAACAGGAACTCATCTCTTATTGTAAGGC GTATGACATTGTTCCAGTAGCATGGGGTCCACTAGATCCTGTGCCTAATAAGGATATATTAACAACCATTGGTAACCATT ATGGTAAGACTTGGGCACAAATACTACTTAGACATCAAATACAAAAAGGTGTCGTTGTCATACCAAAGAGTCACAATAAA TTAAGACAATTTGAAAATATAAATATCTTTGATTTCACATTATCTTTAGAAGATATGCGTAAAATAGAAGAATAA
Upstream 100 bases:
>100_bases TGAAAACGGTTATAAGATTGTTCAAGACAGATCGATTGAAAAAATTGGTGAAGGCTTGAAACAAGCCTACCAAGAAGTTA TCAAAATTAAGAGGTAACCT
Downstream 100 bases:
>100_bases TTATCATTACTTATGTATTTTCACGAAAAAAAGATTTATAATGTTATAATATTAAAGTTGATATAATTTAGGAGGAAACT ATGAAATTTGAACATATAAA
Product: aldo/keto reductase
Products: NA
Alternate protein names: GR; Methylglyoxal reductase [H]
Number of amino acids: Translated: 264; Mature: 264
Protein sequence:
>264_residues MEYLTLHNGFKVPVVGMGANTFGKVNHDFYGALDNDTKELIWAYENGYRLIDTAIVYRNETVIAKSIKDAHLNRKDVMVT SKIPTKELPLEDDEKIEAMIQSSINIFGGYVDIYLIHHPSTDEINLKVWKALESHYLKGHFKAIGVSNFSKEQLDYIMKY ANIKPMMNQIESNPANWQQELISYCKAYDIVPVAWGPLDPVPNKDILTTIGNHYGKTWAQILLRHQIQKGVVVIPKSHNK LRQFENINIFDFTLSLEDMRKIEE
Sequences:
>Translated_264_residues MEYLTLHNGFKVPVVGMGANTFGKVNHDFYGALDNDTKELIWAYENGYRLIDTAIVYRNETVIAKSIKDAHLNRKDVMVT SKIPTKELPLEDDEKIEAMIQSSINIFGGYVDIYLIHHPSTDEINLKVWKALESHYLKGHFKAIGVSNFSKEQLDYIMKY ANIKPMMNQIESNPANWQQELISYCKAYDIVPVAWGPLDPVPNKDILTTIGNHYGKTWAQILLRHQIQKGVVVIPKSHNK LRQFENINIFDFTLSLEDMRKIEE >Mature_264_residues MEYLTLHNGFKVPVVGMGANTFGKVNHDFYGALDNDTKELIWAYENGYRLIDTAIVYRNETVIAKSIKDAHLNRKDVMVT SKIPTKELPLEDDEKIEAMIQSSINIFGGYVDIYLIHHPSTDEINLKVWKALESHYLKGHFKAIGVSNFSKEQLDYIMKY ANIKPMMNQIESNPANWQQELISYCKAYDIVPVAWGPLDPVPNKDILTTIGNHYGKTWAQILLRHQIQKGVVVIPKSHNK LRQFENINIFDFTLSLEDMRKIEE
Specific function: Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis [H]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI5174695, Length=300, Percent_Identity=33, Blast_Score=143, Evalue=1e-34, Organism=Homo sapiens, GI24497577, Length=296, Percent_Identity=32.7702702702703, Blast_Score=138, Evalue=5e-33, Organism=Homo sapiens, GI5174391, Length=296, Percent_Identity=32.7702702702703, Blast_Score=138, Evalue=5e-33, Organism=Homo sapiens, GI5453543, Length=301, Percent_Identity=32.2259136212625, Blast_Score=132, Evalue=4e-31, Organism=Homo sapiens, GI24497583, Length=303, Percent_Identity=33.6633663366337, Blast_Score=129, Evalue=2e-30, Organism=Homo sapiens, GI310109922, Length=282, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=3e-30, Organism=Homo sapiens, GI310109920, Length=301, Percent_Identity=31.8936877076412, Blast_Score=128, Evalue=7e-30, Organism=Homo sapiens, GI223468663, Length=301, Percent_Identity=33.5548172757475, Blast_Score=127, Evalue=9e-30, Organism=Homo sapiens, GI45446745, Length=301, Percent_Identity=31.2292358803987, Blast_Score=126, Evalue=2e-29, Organism=Homo sapiens, GI4503285, Length=301, Percent_Identity=31.2292358803987, Blast_Score=126, Evalue=2e-29, Organism=Homo sapiens, GI24497585, Length=302, Percent_Identity=31.4569536423841, Blast_Score=125, Evalue=3e-29, Organism=Homo sapiens, GI300116273, Length=286, Percent_Identity=31.4685314685315, Blast_Score=125, Evalue=4e-29, Organism=Homo sapiens, GI93277124, Length=305, Percent_Identity=30.4918032786885, Blast_Score=114, Evalue=7e-26, Organism=Homo sapiens, GI291291012, Length=296, Percent_Identity=31.0810810810811, Blast_Score=108, Evalue=4e-24, Organism=Homo sapiens, GI4502049, Length=296, Percent_Identity=30.0675675675676, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI300116271, Length=279, Percent_Identity=29.0322580645161, Blast_Score=106, Evalue=3e-23, Organism=Homo sapiens, GI310109924, Length=140, Percent_Identity=37.1428571428571, Blast_Score=91, Evalue=1e-18, Organism=Escherichia coli, GI87082198, Length=266, Percent_Identity=31.203007518797, Blast_Score=127, Evalue=7e-31, Organism=Escherichia coli, GI1786400, Length=261, Percent_Identity=26.8199233716475, Blast_Score=82, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17564128, Length=307, Percent_Identity=33.5504885993485, Blast_Score=139, Evalue=2e-33, Organism=Caenorhabditis elegans, GI71998625, Length=267, Percent_Identity=32.9588014981273, Blast_Score=138, Evalue=3e-33, Organism=Caenorhabditis elegans, GI17537077, Length=302, Percent_Identity=29.8013245033113, Blast_Score=116, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17537075, Length=302, Percent_Identity=29.8013245033113, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17550248, Length=298, Percent_Identity=29.1946308724832, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17566692, Length=299, Percent_Identity=30.4347826086957, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17537079, Length=303, Percent_Identity=27.0627062706271, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI17561300, Length=279, Percent_Identity=27.2401433691756, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17561298, Length=278, Percent_Identity=26.978417266187, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17562292, Length=281, Percent_Identity=28.1138790035587, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17552492, Length=240, Percent_Identity=26.6666666666667, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17538386, Length=281, Percent_Identity=27.0462633451957, Blast_Score=83, Evalue=1e-16, Organism=Saccharomyces cerevisiae, GI6322556, Length=274, Percent_Identity=28.8321167883212, Blast_Score=115, Evalue=6e-27, Organism=Saccharomyces cerevisiae, GI6324694, Length=293, Percent_Identity=31.3993174061433, Blast_Score=115, Evalue=6e-27, Organism=Saccharomyces cerevisiae, GI6320576, Length=293, Percent_Identity=30.7167235494881, Blast_Score=115, Evalue=7e-27, Organism=Saccharomyces cerevisiae, GI6319625, Length=293, Percent_Identity=30.3754266211604, Blast_Score=111, Evalue=1e-25, Organism=Saccharomyces cerevisiae, GI6320079, Length=283, Percent_Identity=29.3286219081272, Blast_Score=111, Evalue=1e-25, Organism=Saccharomyces cerevisiae, GI6321896, Length=311, Percent_Identity=28.9389067524116, Blast_Score=110, Evalue=3e-25, Organism=Drosophila melanogaster, GI24663317, Length=291, Percent_Identity=32.9896907216495, Blast_Score=148, Evalue=4e-36, Organism=Drosophila melanogaster, GI24644950, Length=306, Percent_Identity=33.9869281045752, Blast_Score=142, Evalue=2e-34, Organism=Drosophila melanogaster, GI21356425, Length=292, Percent_Identity=33.5616438356164, Blast_Score=137, Evalue=7e-33, Organism=Drosophila melanogaster, GI221378297, Length=326, Percent_Identity=31.9018404907975, Blast_Score=135, Evalue=4e-32, Organism=Drosophila melanogaster, GI20129731, Length=291, Percent_Identity=31.6151202749141, Blast_Score=134, Evalue=5e-32, Organism=Drosophila melanogaster, GI24657054, Length=294, Percent_Identity=32.6530612244898, Blast_Score=128, Evalue=3e-30, Organism=Drosophila melanogaster, GI45553081, Length=292, Percent_Identity=30.1369863013699, Blast_Score=127, Evalue=1e-29, Organism=Drosophila melanogaster, GI281366140, Length=251, Percent_Identity=31.4741035856574, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI24662781, Length=289, Percent_Identity=30.7958477508651, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI24662789, Length=299, Percent_Identity=27.4247491638796, Blast_Score=108, Evalue=2e-24, Organism=Drosophila melanogaster, GI24662785, Length=284, Percent_Identity=30.9859154929577, Blast_Score=108, Evalue=3e-24,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: =1.1.1.283 [H]
Molecular weight: Translated: 30399; Mature: 30399
Theoretical pI: Translated: 6.68; Mature: 6.68
Prosite motif: PS00062 ALDOKETO_REDUCTASE_2 ; PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEYLTLHNGFKVPVVGMGANTFGKVNHDFYGALDNDTKELIWAYENGYRLIDTAIVYRNE CCEEEECCCCEEEEEECCCCCCCCCCCCEECCCCCCCHHEEEEECCCCEEEEEEEEEECC TVIAKSIKDAHLNRKDVMVTSKIPTKELPLEDDEKIEAMIQSSINIFGGYVDIYLIHHPS EEEEHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCC TDEINLKVWKALESHYLKGHFKAIGVSNFSKEQLDYIMKYANIKPMMNQIESNPANWQQE CCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHCCCCCHHHHH LISYCKAYDIVPVAWGPLDPVPNKDILTTIGNHYGKTWAQILLRHQIQKGVVVIPKSHNK HHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHH LRQFENINIFDFTLSLEDMRKIEE HHHHCCCEEEEEEECHHHHHHHCC >Mature Secondary Structure MEYLTLHNGFKVPVVGMGANTFGKVNHDFYGALDNDTKELIWAYENGYRLIDTAIVYRNE CCEEEECCCCEEEEEECCCCCCCCCCCCEECCCCCCCHHEEEEECCCCEEEEEEEEEECC TVIAKSIKDAHLNRKDVMVTSKIPTKELPLEDDEKIEAMIQSSINIFGGYVDIYLIHHPS EEEEHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCC TDEINLKVWKALESHYLKGHFKAIGVSNFSKEQLDYIMKYANIKPMMNQIESNPANWQQE CCCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHCCCCCHHHHH LISYCKAYDIVPVAWGPLDPVPNKDILTTIGNHYGKTWAQILLRHQIQKGVVVIPKSHNK HHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHH LRQFENINIFDFTLSLEDMRKIEE HHHHCCCEEEEEEECHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9639930; 9384377 [H]