Click here to switch to the map view.

The map label for this gene is tig [H]

Identifier: 162447397

GI number: 162447397

Start: 568986

End: 570269

Strand: Direct

Name: tig [H]

Synonym: ACL_0535

Alternate gene names: 162447397

Gene position: 568986-570269 (Clockwise)

Preceding gene: 162447396

Following gene: 162447398

Centisome position: 38.01

GC content: 31.62

Gene sequence:

>1284_bases
ATGAAATTTGAACATATAAAAAAGAATCATGTAAAATTTACTTTTACAGTAACACCTGCAGAATTTGAACATGCATTAGA
ACATGCTTTTGCACACATTAAAGATGATGTAGAAATTAAAGGATTTAGAAAAGGTAAAGTAACTCAAAAAGTTTACGAAC
AAAAATTTGGTGAAACAGCATTATATGCAGAAGCATTAAACCACGCAATTGGTCATAAATATAATGATGCTACACTAGTA
AAAGACTTTACAATTGTTTCAGATCCAATGAATATTGATCTAGATTTCGATAAAATCTCAAGAACAGAAGATTTTGAAGT
AAGTTTTGAAGTTGCAATCAAACCTGAAGTTGAAATTGAAAACTATAAAGGTGTTGAAGTTGCTAAAGTAGATACAGAAG
TAACAGAAAAAGAAGTTGATGAAAACATTAACAGCCTATTAGCTCAAAATGCTATTTTAGAACCTAAAGAAGGTGCACTA
GAAAATGGCGATACAGCAATCTTTGATTTCGAAGGATTCCAAGATGGTGTTGCATTTGAAGGTGGGAAAGCTGAAAACTT
CAGTTTAGAAATCGGTAGTGGTCAATTCATTCCTGGTTTTGAAGAAGGTATGTTAGGCTTAAAAGTTGGTGAATCACGCG
ATGTGGATGTTACTTTCCCTGAACAATACCAAGCTGAAAACCTAGCAGGTAAACCGGCAGTATTTAAAGTTGTATTACAC
GAAATTAAATCTAAAAAATTAGCAGAATTAAATGATGAATGGGTTGTATCACTTAACCGTGAAGGTATCTCAACTGTTGA
TCAATTAAAAGCATCAATCAAAGCAGATTTAGAAGCATCTAAACAAGAACAAGCTAAAAGAGAATTAACTGATGCAGTTA
TCACTGAAGTAGTTAAATTAGCTAAAGTTGAAGTGCCACAATCTATGTTTGATTCAGAAATCGAAAACTTCAAGAAAAAT
GTTGAAGCTCAAGCTAAACAATATCAATTAGATATGGATACATTCATCCAATTATCAGGATTAACTAAAGAATTATTCGA
ACAACAAGCTAAAGAACAAGCTGAAAAACGTGTACTTCAATCTCTAGTAATCGAAGCGATTGCTAAGAAAGAAAACTTCA
CTGCTACACCTGAAGAATTAAGTTTGCGTTATGAAGAATTAGCAAACCATTACAAAATGGAAGTTAATGAAATTAAAAAG
TATATCTCAGATGAACTAGTAATGAATGATATCGCATTTGAAAAAGCAGTAACATTCTTAGTAGAAAACGCAGTACAAAA
ATAA

Upstream 100 bases:

>100_bases
TGCGTAAAATAGAAGAATAATTATCATTACTTATGTATTTTCACGAAAAAAAGATTTATAATGTTATAATATTAAAGTTG
ATATAATTTAGGAGGAAACT

Downstream 100 bases:

>100_bases
ATATAAAAGTAGCCTCTGAAGCTTCAGAGGCTTTCTTATAACTATAAATATGATAAAAGATGGGATAACGATTGGCACTC
ATGCATTATGATTGCTAATT

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MKFEHIKKNHVKFTFTVTPAEFEHALEHAFAHIKDDVEIKGFRKGKVTQKVYEQKFGETALYAEALNHAIGHKYNDATLV
KDFTIVSDPMNIDLDFDKISRTEDFEVSFEVAIKPEVEIENYKGVEVAKVDTEVTEKEVDENINSLLAQNAILEPKEGAL
ENGDTAIFDFEGFQDGVAFEGGKAENFSLEIGSGQFIPGFEEGMLGLKVGESRDVDVTFPEQYQAENLAGKPAVFKVVLH
EIKSKKLAELNDEWVVSLNREGISTVDQLKASIKADLEASKQEQAKRELTDAVITEVVKLAKVEVPQSMFDSEIENFKKN
VEAQAKQYQLDMDTFIQLSGLTKELFEQQAKEQAEKRVLQSLVIEAIAKKENFTATPEELSLRYEELANHYKMEVNEIKK
YISDELVMNDIAFEKAVTFLVENAVQK

Sequences:

>Translated_427_residues
MKFEHIKKNHVKFTFTVTPAEFEHALEHAFAHIKDDVEIKGFRKGKVTQKVYEQKFGETALYAEALNHAIGHKYNDATLV
KDFTIVSDPMNIDLDFDKISRTEDFEVSFEVAIKPEVEIENYKGVEVAKVDTEVTEKEVDENINSLLAQNAILEPKEGAL
ENGDTAIFDFEGFQDGVAFEGGKAENFSLEIGSGQFIPGFEEGMLGLKVGESRDVDVTFPEQYQAENLAGKPAVFKVVLH
EIKSKKLAELNDEWVVSLNREGISTVDQLKASIKADLEASKQEQAKRELTDAVITEVVKLAKVEVPQSMFDSEIENFKKN
VEAQAKQYQLDMDTFIQLSGLTKELFEQQAKEQAEKRVLQSLVIEAIAKKENFTATPEELSLRYEELANHYKMEVNEIKK
YISDELVMNDIAFEKAVTFLVENAVQK
>Mature_427_residues
MKFEHIKKNHVKFTFTVTPAEFEHALEHAFAHIKDDVEIKGFRKGKVTQKVYEQKFGETALYAEALNHAIGHKYNDATLV
KDFTIVSDPMNIDLDFDKISRTEDFEVSFEVAIKPEVEIENYKGVEVAKVDTEVTEKEVDENINSLLAQNAILEPKEGAL
ENGDTAIFDFEGFQDGVAFEGGKAENFSLEIGSGQFIPGFEEGMLGLKVGESRDVDVTFPEQYQAENLAGKPAVFKVVLH
EIKSKKLAELNDEWVVSLNREGISTVDQLKASIKADLEASKQEQAKRELTDAVITEVVKLAKVEVPQSMFDSEIENFKKN
VEAQAKQYQLDMDTFIQLSGLTKELFEQQAKEQAEKRVLQSLVIEAIAKKENFTATPEELSLRYEELANHYKMEVNEIKK
YISDELVMNDIAFEKAVTFLVENAVQK

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=400, Percent_Identity=31, Blast_Score=193, Evalue=1e-50,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 48266; Mature: 48266

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS50059 FKBP_PPIASE ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFEHIKKNHVKFTFTVTPAEFEHALEHAFAHIKDDVEIKGFRKGKVTQKVYEQKFGETA
CCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCHH
LYAEALNHAIGHKYNDATLVKDFTIVSDPMNIDLDFDKISRTEDFEVSFEVAIKPEVEIE
HHHHHHHHHHCCCCCCCEEEEEEEEEECCCEEEECHHHCCCCCCCEEEEEEEECCCEEEC
NYKGVEVAKVDTEVTEKEVDENINSLLAQNAILEPKEGALENGDTAIFDFEGFQDGVAFE
CCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCEEC
GGKAENFSLEIGSGQFIPGFEEGMLGLKVGESRDVDVTFPEQYQAENLAGKPAVFKVVLH
CCCCCCEEEEECCCCCCCCHHHCCEEEEECCCCCCEEECCHHHHHHCCCCCHHHHHHHHH
EIKSKKLAELNDEWVVSLNREGISTVDQLKASIKADLEASKQEQAKRELTDAVITEVVKL
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKVEVPQSMFDSEIENFKKNVEAQAKQYQLDMDTFIQLSGLTKELFEQQAKEQAEKRVLQ
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
SLVIEAIAKKENFTATPEELSLRYEELANHYKMEVNEIKKYISDELVMNDIAFEKAVTFL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VENAVQK
HHHHHCC
>Mature Secondary Structure
MKFEHIKKNHVKFTFTVTPAEFEHALEHAFAHIKDDVEIKGFRKGKVTQKVYEQKFGETA
CCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCHH
LYAEALNHAIGHKYNDATLVKDFTIVSDPMNIDLDFDKISRTEDFEVSFEVAIKPEVEIE
HHHHHHHHHHCCCCCCCEEEEEEEEEECCCEEEECHHHCCCCCCCEEEEEEEECCCEEEC
NYKGVEVAKVDTEVTEKEVDENINSLLAQNAILEPKEGALENGDTAIFDFEGFQDGVAFE
CCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCEEC
GGKAENFSLEIGSGQFIPGFEEGMLGLKVGESRDVDVTFPEQYQAENLAGKPAVFKVVLH
CCCCCCEEEEECCCCCCCCHHHCCEEEEECCCCCCEEECCHHHHHHCCCCCHHHHHHHHH
EIKSKKLAELNDEWVVSLNREGISTVDQLKASIKADLEASKQEQAKRELTDAVITEVVKL
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKVEVPQSMFDSEIENFKKNVEAQAKQYQLDMDTFIQLSGLTKELFEQQAKEQAEKRVLQ
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
SLVIEAIAKKENFTATPEELSLRYEELANHYKMEVNEIKKYISDELVMNDIAFEKAVTFL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VENAVQK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA