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The map label for this gene is mhpC [C]

Identifier: 162447370

GI number: 162447370

Start: 532077

End: 532961

Strand: Direct

Name: mhpC [C]

Synonym: ACL_0508

Alternate gene names: 162447370

Gene position: 532077-532961 (Clockwise)

Preceding gene: 162447369

Following gene: 162447371

Centisome position: 35.54

GC content: 32.54

Gene sequence:

>885_bases
GTGAAATTAAAACAAGTTGAACTTAAAAATGGTGAAACCATAAGCTATTATGAACAAGGAAATTCTAAGGAGACATTACT
GCTAATTCATGGTAATACATCCTCAGCGATATTCTTTGAACCATTAATGCAAATATTACCAAAAAACCAAAGTGTCATAG
CACCTGATTTAAGAGGTTTTGGTAATTCAAGTTATAAAAAAAATATTGAAACTTTATCAGATTTTGCCGAAGATATAAAG
TTATTACTAGAGCAATTAGGATTAAATTGCGTTAGTATACTAGGATGGTCTCTAGGTGGTGCCATTGCGATGGAATTTGC
ATCTACTTATCCAAATATGGTAAGTAATCTTATTCTATTGTCATCTGGCTCCCCTAAAGGATATCCTGTATTTACAAAGG
ATGAAAAAGGGCAACCAATGATTCCTCATGTATACAAGAAAAAAGAAGACATGGCGCTTGATCCTGTTCAAGTCCTACCA
CTTCTTAATATTTATGAAACAAAAAATAGTCAAATGCTTGCAACCATCTATAACTATGTAATCTATACAGGACATAAAAA
GCCTGACAATGATGCAAACCTAAGATGGATGAATGAAGCAGTTAAACAAAGAAACTTAGTGGATGTAGACTGGGCACTAG
CAAATTTCAATATTTCTAGTGAACCAAGCTTATACCAACTAGGAAACAATAAACTATCTAACCTAAAAGCTAAAACATTG
ATTATTTGGGGTGACAAAGATGTTACAGTACCAAAAATTATGTTTGATGAAACTGTTAGGTTACTACCAGAAGCTACTGT
ATTAGTATATGAAAATGCAGGTCATTCTATTGTAGTAGATGAAACTGAAAAATTAGCAATCGATATTGTTCATTTCATCT
CCTAG

Upstream 100 bases:

>100_bases
TGCTTCCATGTATGAAGTACCTGAAGTGTTTACAACAATCTTAATCGGATTTTTAAAGACTAAATTAGAATTTACGATAT
AACACTAGGAGGGGATATTA

Downstream 100 bases:

>100_bases
TCTTGATTTTTATTCATGAGTAGAGTTATGTCGTTGACATGACTCTATTTTCATAAAATAAGGCATACTTATGACCAAAA
TAACTCATATTTTTGGGTTT

Product: alpha/beta hydrolase superfamily protein

Products: NA

Alternate protein names: Atropine acylhydrolase; Atropinesterase [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKLKQVELKNGETISYYEQGNSKETLLLIHGNTSSAIFFEPLMQILPKNQSVIAPDLRGFGNSSYKKNIETLSDFAEDIK
LLLEQLGLNCVSILGWSLGGAIAMEFASTYPNMVSNLILLSSGSPKGYPVFTKDEKGQPMIPHVYKKKEDMALDPVQVLP
LLNIYETKNSQMLATIYNYVIYTGHKKPDNDANLRWMNEAVKQRNLVDVDWALANFNISSEPSLYQLGNNKLSNLKAKTL
IIWGDKDVTVPKIMFDETVRLLPEATVLVYENAGHSIVVDETEKLAIDIVHFIS

Sequences:

>Translated_294_residues
MKLKQVELKNGETISYYEQGNSKETLLLIHGNTSSAIFFEPLMQILPKNQSVIAPDLRGFGNSSYKKNIETLSDFAEDIK
LLLEQLGLNCVSILGWSLGGAIAMEFASTYPNMVSNLILLSSGSPKGYPVFTKDEKGQPMIPHVYKKKEDMALDPVQVLP
LLNIYETKNSQMLATIYNYVIYTGHKKPDNDANLRWMNEAVKQRNLVDVDWALANFNISSEPSLYQLGNNKLSNLKAKTL
IIWGDKDVTVPKIMFDETVRLLPEATVLVYENAGHSIVVDETEKLAIDIVHFIS
>Mature_294_residues
MKLKQVELKNGETISYYEQGNSKETLLLIHGNTSSAIFFEPLMQILPKNQSVIAPDLRGFGNSSYKKNIETLSDFAEDIK
LLLEQLGLNCVSILGWSLGGAIAMEFASTYPNMVSNLILLSSGSPKGYPVFTKDEKGQPMIPHVYKKKEDMALDPVQVLP
LLNIYETKNSQMLATIYNYVIYTGHKKPDNDANLRWMNEAVKQRNLVDVDWALANFNISSEPSLYQLGNNKLSNLKAKTL
IIWGDKDVTVPKIMFDETVRLLPEATVLVYENAGHSIVVDETEKLAIDIVHFIS

Specific function: Alkaloid degradation [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Homo sapiens, GI189027141, Length=290, Percent_Identity=26.8965517241379, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI87081721, Length=292, Percent_Identity=23.972602739726, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.10 [H]

Molecular weight: Translated: 32974; Mature: 32974

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKQVELKNGETISYYEQGNSKETLLLIHGNTSSAIFFEPLMQILPKNQSVIAPDLRGF
CCCEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCEECCCHHCC
GNSSYKKNIETLSDFAEDIKLLLEQLGLNCVSILGWSLGGAIAMEFASTYPNMVSNLILL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCEEEE
SSGSPKGYPVFTKDEKGQPMIPHVYKKKEDMALDPVQVLPLLNIYETKNSQMLATIYNYV
ECCCCCCCEEEECCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHEEECCCCEEHHHHHEEH
IYTGHKKPDNDANLRWMNEAVKQRNLVDVDWALANFNISSEPSLYQLGNNKLSNLKAKTL
EEECCCCCCCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCEECCCCHHCCCEEEEE
IIWGDKDVTVPKIMFDETVRLLPEATVLVYENAGHSIVVDETEKLAIDIVHFIS
EEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCEEEEECCHHHHHHHHHHCC
>Mature Secondary Structure
MKLKQVELKNGETISYYEQGNSKETLLLIHGNTSSAIFFEPLMQILPKNQSVIAPDLRGF
CCCEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCEECCCHHCC
GNSSYKKNIETLSDFAEDIKLLLEQLGLNCVSILGWSLGGAIAMEFASTYPNMVSNLILL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCEEEE
SSGSPKGYPVFTKDEKGQPMIPHVYKKKEDMALDPVQVLPLLNIYETKNSQMLATIYNYV
ECCCCCCCEEEECCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHEEECCCCEEHHHHHEEH
IYTGHKKPDNDANLRWMNEAVKQRNLVDVDWALANFNISSEPSLYQLGNNKLSNLKAKTL
EEECCCCCCCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCEECCCCHHCCCEEEEE
IIWGDKDVTVPKIMFDETVRLLPEATVLVYENAGHSIVVDETEKLAIDIVHFIS
EEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCEEEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA