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The map label for this gene is fabZ [H]

Identifier: 162447328

GI number: 162447328

Start: 490453

End: 490881

Strand: Direct

Name: fabZ [H]

Synonym: ACL_0465

Alternate gene names: 162447328

Gene position: 490453-490881 (Clockwise)

Preceding gene: 162447327

Following gene: 162447329

Centisome position: 32.76

GC content: 34.27

Gene sequence:

>429_bases
ATGGCATTATTAAATAGAGAACAAATTCAAGAAATATTACCACATAGAGATCCTTTTTTAATGGTTGATGAAGTTTTAGA
ACTTGTTGAAAAAGAAAAATGTGTAGGTATTAAATATGTAAAAGCAGAAGAATATTACTTTAAAGGACATTTTCCTCAGT
ATCCTGTAATGCCTGGTGTATTAATACTAGAAACAATGGCTCAAGTTGGTGCGATTGCTTTACTAAGTATTCCAGAGTTC
AAAGGTAAAATCGGATTTTTTACAGGAGCTAACAACGTTAAATGGCGTAAACAAGTACGTCCAGGAGATACTTTAAAAGT
TGAAACAGTATTAACCCGTATTCGTGGTGCTTTTGGTGTGGGTAGCGCTAAAGCATGGGTAGAAGGCGAATTAGTATGTG
AAGCTGATATTAGTTTTGCTATTGGCTGA

Upstream 100 bases:

>100_bases
ACAAAGCCGTAAAACGTGATATCAATTATGCTATGAATATCAACGTAGGTTTTGGTGGCCAAAATGCAGTTGTGTTATAT
AAGAAATATGGAGAATAAAT

Downstream 100 bases:

>100_bases
TCATGGTTAAAGTAAAATTAATAGAGTTTAAAAAAATACCCTCAACCAGTGACTATCTAAAACAAAATTATGAAAAACTG
GACTCTTTTACCTTTGTAAG

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MALLNREQIQEILPHRDPFLMVDEVLELVEKEKCVGIKYVKAEEYYFKGHFPQYPVMPGVLILETMAQVGAIALLSIPEF
KGKIGFFTGANNVKWRKQVRPGDTLKVETVLTRIRGAFGVGSAKAWVEGELVCEADISFAIG

Sequences:

>Translated_142_residues
MALLNREQIQEILPHRDPFLMVDEVLELVEKEKCVGIKYVKAEEYYFKGHFPQYPVMPGVLILETMAQVGAIALLSIPEF
KGKIGFFTGANNVKWRKQVRPGDTLKVETVLTRIRGAFGVGSAKAWVEGELVCEADISFAIG
>Mature_141_residues
ALLNREQIQEILPHRDPFLMVDEVLELVEKEKCVGIKYVKAEEYYFKGHFPQYPVMPGVLILETMAQVGAIALLSIPEFK
GKIGFFTGANNVKWRKQVRPGDTLKVETVLTRIRGAFGVGSAKAWVEGELVCEADISFAIG

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:
GO:0016829: Beta-hydroxyacyl-(Acyl-carrier-protein) dehydratase

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=139, Percent_Identity=39.568345323741, Blast_Score=101, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 15884; Mature: 15753

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLNREQIQEILPHRDPFLMVDEVLELVEKEKCVGIKYVKAEEYYFKGHFPQYPVMPGV
CCCCCHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCEEEEECCCEEECCCCCCCCCCCHH
LILETMAQVGAIALLSIPEFKGKIGFFTGANNVKWRKQVRPGDTLKVETVLTRIRGAFGV
HHHHHHHHHHHEEEEECCCCCCCEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHCCC
GSAKAWVEGELVCEADISFAIG
CCCCEEECCEEEEECCCEEECC
>Mature Secondary Structure 
ALLNREQIQEILPHRDPFLMVDEVLELVEKEKCVGIKYVKAEEYYFKGHFPQYPVMPGV
CCCCHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCEEEEECCCEEECCCCCCCCCCCHH
LILETMAQVGAIALLSIPEFKGKIGFFTGANNVKWRKQVRPGDTLKVETVLTRIRGAFGV
HHHHHHHHHHHEEEEECCCCCCCEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHCCC
GSAKAWVEGELVCEADISFAIG
CCCCEEECCEEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA