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The map label for this gene is fabH1

Identifier: 162447324

GI number: 162447324

Start: 486589

End: 487521

Strand: Direct

Name: fabH1

Synonym: ACL_0461

Alternate gene names: 162447324

Gene position: 486589-487521 (Clockwise)

Preceding gene: 162447323

Following gene: 162447325

Centisome position: 32.5

GC content: 32.8

Gene sequence:

>933_bases
ATGAAGAACTTGCCGATTAAAATAGTAAGCACTGGTCGTTATGCACCAGATAATATTATGACTAATGATGATTTTAGTAA
AATATTAGATACGAATGATGAATGGATAACTACTAGAACAGGTATTAAAAGACGCCATATTGCTCAAGGTGAAACCGCAA
TTGATATGGCATATAAAGCAGCTTTAAAGGCTGTTGAAAATAAAAATTATGATAAAGAAAAAATTGATTTAATTATTGTT
GCAAGTATTACATCACCAGTTAAAACACCATCTATTGCAAATTTAATCCAAGCTAAACTTGGACTAAATCATAAAAATAT
TGTAGCATTTGATATTAATGCTGCATGTAGTGGGTTTGTTTATGCGGTTGAAATTGCAGCAAGTATGATTTCATCAGGTA
ATTATAAATCAGCATTAGTTATTGGTTCTGAACATATGTCATCTATCCTTGATTGGGAAGACCGTTCAACTGCTATCCTA
TTTGGTGATGCTGCTGGTGCAGCAATTATTGAAGTAAGTGATAATCCAAAAGATAATGCATATTTCTGGAATGGTTCTAG
AGGTGATGATACGGGTATTTTATGGATTGATCCAAAAGTAAAGATGGCTGGACGTGAAGTCTATAAATTTGCAGTGGATA
TTATGCCTAAAGCTATTCATAAAGTACTTGAAAAAGCAGGACTTACAATTGATGATATCGATTATATTATTCCTCATCAA
GCAAACTACAGAATTATTCAAAGTGTTGCTAAAGATATGAATTTACCGATTGAAAGATTTTTAATGAACCTAGAAGAGTA
TGGTAATACATCCGCAGCAAGTATTCCATTCTTATTAGATGAACATAAGACTAATAACCCTGAAGTTAAAAGAGTTATAT
TAGTTGGATTTGGCGGCGGATTTACTTGGGGTGCAGCCATCCTAAATGTGTAG

Upstream 100 bases:

>100_bases
CAACTAACAAAATTAATGAAAACACCTGTAGAAAAACTTCTTGTTAATAGATATGACAAGTTCAAAAAAATGGGTGAATA
CGAAGAAAGTGTGATCAAAA

Downstream 100 bases:

>100_bases
GTAACTTTTATGAAAACAGCGATTTTATTTTCTGGTCAAGGTGCTCAATACGTCAACATGGGACTAGATTTCATTGAAAA
TGTTCCAGAGTTAAAGCATA

Product: beta-ketoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKNLPIKIVSTGRYAPDNIMTNDDFSKILDTNDEWITTRTGIKRRHIAQGETAIDMAYKAALKAVENKNYDKEKIDLIIV
ASITSPVKTPSIANLIQAKLGLNHKNIVAFDINAACSGFVYAVEIAASMISSGNYKSALVIGSEHMSSILDWEDRSTAIL
FGDAAGAAIIEVSDNPKDNAYFWNGSRGDDTGILWIDPKVKMAGREVYKFAVDIMPKAIHKVLEKAGLTIDDIDYIIPHQ
ANYRIIQSVAKDMNLPIERFLMNLEEYGNTSAASIPFLLDEHKTNNPEVKRVILVGFGGGFTWGAAILNV

Sequences:

>Translated_310_residues
MKNLPIKIVSTGRYAPDNIMTNDDFSKILDTNDEWITTRTGIKRRHIAQGETAIDMAYKAALKAVENKNYDKEKIDLIIV
ASITSPVKTPSIANLIQAKLGLNHKNIVAFDINAACSGFVYAVEIAASMISSGNYKSALVIGSEHMSSILDWEDRSTAIL
FGDAAGAAIIEVSDNPKDNAYFWNGSRGDDTGILWIDPKVKMAGREVYKFAVDIMPKAIHKVLEKAGLTIDDIDYIIPHQ
ANYRIIQSVAKDMNLPIERFLMNLEEYGNTSAASIPFLLDEHKTNNPEVKRVILVGFGGGFTWGAAILNV
>Mature_310_residues
MKNLPIKIVSTGRYAPDNIMTNDDFSKILDTNDEWITTRTGIKRRHIAQGETAIDMAYKAALKAVENKNYDKEKIDLIIV
ASITSPVKTPSIANLIQAKLGLNHKNIVAFDINAACSGFVYAVEIAASMISSGNYKSALVIGSEHMSSILDWEDRSTAIL
FGDAAGAAIIEVSDNPKDNAYFWNGSRGDDTGILWIDPKVKMAGREVYKFAVDIMPKAIHKVLEKAGLTIDDIDYIIPHQ
ANYRIIQSVAKDMNLPIERFLMNLEEYGNTSAASIPFLLDEHKTNNPEVKRVILVGFGGGFTWGAAILNV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family

Homologues:

Organism=Escherichia coli, GI1787333, Length=315, Percent_Identity=40.6349206349206, Blast_Score=232, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABH_ACHLI (A9NFF0)

Other databases:

- EMBL:   CP000896
- RefSeq:   YP_001620456.1
- ProteinModelPortal:   A9NFF0
- SMR:   A9NFF0
- GeneID:   5803120
- GenomeReviews:   CP000896_GR
- KEGG:   acl:ACL_0461
- HOGENOM:   HBG649927
- OMA:   VIANDIE
- BioCyc:   ALAI441768:ACL_0461-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01815
- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038
- Gene3D:   G3DSA:3.40.47.10
- TIGRFAMs:   TIGR00747

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C; SSF53901 Thiolase-like

EC number: =2.3.1.180

Molecular weight: Translated: 34122; Mature: 34122

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: ACT_SITE 116-116 ACT_SITE 239-239 ACT_SITE 269-269

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLPIKIVSTGRYAPDNIMTNDDFSKILDTNDEWITTRTGIKRRHIAQGETAIDMAYKA
CCCCCEEEEECCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCHHHHCCCCHHHHHHHHH
ALKAVENKNYDKEKIDLIIVASITSPVKTPSIANLIQAKLGLNHKNIVAFDINAACSGFV
HHHHHHCCCCCCHHEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHH
YAVEIAASMISSGNYKSALVIGSEHMSSILDWEDRSTAILFGDAAGAAIIEVSDNPKDNA
HHHHHHHHHHCCCCCCEEEEECHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCC
YFWNGSRGDDTGILWIDPKVKMAGREVYKFAVDIMPKAIHKVLEKAGLTIDDIDYIIPHQ
EEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEECCCC
ANYRIIQSVAKDMNLPIERFLMNLEEYGNTSAASIPFLLDEHKTNNPEVKRVILVGFGGG
CCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEEEEEEECCC
FTWGAAILNV
HHHHHHEECC
>Mature Secondary Structure
MKNLPIKIVSTGRYAPDNIMTNDDFSKILDTNDEWITTRTGIKRRHIAQGETAIDMAYKA
CCCCCEEEEECCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCHHHHCCCCHHHHHHHHH
ALKAVENKNYDKEKIDLIIVASITSPVKTPSIANLIQAKLGLNHKNIVAFDINAACSGFV
HHHHHHCCCCCCHHEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHH
YAVEIAASMISSGNYKSALVIGSEHMSSILDWEDRSTAILFGDAAGAAIIEVSDNPKDNA
HHHHHHHHHHCCCCCCEEEEECHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCC
YFWNGSRGDDTGILWIDPKVKMAGREVYKFAVDIMPKAIHKVLEKAGLTIDDIDYIIPHQ
EEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEECCCC
ANYRIIQSVAKDMNLPIERFLMNLEEYGNTSAASIPFLLDEHKTNNPEVKRVILVGFGGG
CCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEEEEEEEECCC
FTWGAAILNV
HHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA