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The map label for this gene is holB [H]

Identifier: 162446998

GI number: 162446998

Start: 109489

End: 110439

Strand: Direct

Name: holB [H]

Synonym: ACL_0128

Alternate gene names: 162446998

Gene position: 109489-110439 (Clockwise)

Preceding gene: 162446997

Following gene: 162446999

Centisome position: 7.31

GC content: 30.07

Gene sequence:

>951_bases
ATGAATAAAATAGTTGAAAGATTTAAATATGCAATTGAAAAAGAAAGACTTTCCCACTTATATGTTATAAGTGGGTCTTT
AGGTCTTACCAAGCAAAATCTAGTTAAAGATATCGCGTATTTAATCTTTAAACATCATAAGGACTATCCAACTTTAAAAC
ACCAACTAGATAGTTTTAATCATCCAAACTTAGTTTACATCTCAGGGGAAGGTCAATCTATAAAAAAAGACCAAATCATG
AGTTTACAACAAGAGTTTTCTAAAACATCATTAGTCAGTGGGCCTAGAATCTTTATTATTGAACAAGCTGAGACGATGTC
TACTCAAGCAGCAAACTCACTTCTTAAATTCTTAGAAGAACCAAAAGATGATGATACCATTGGATTTTTACTCGTAGATG
ATATCAATCTAATGTTACCTACTATTTTGAGCCGTGCTCAAATTATTAGGTTAACAGACACTTTTGATGATAGTTTTATA
CAAGTTTTAATGGAACAAGAAATAGATATTAAAAATGCACATTTTATTGCATCCTTGACTAAAGAGTTAAACGAAGCTTT
AGCTATTTTTGCAGACCAAAAATATATGGATACTGTGGAGTTTATTGATACCTTTATCAACTGGCTTAACAATCCAAGAA
CACCGCTTACGCCACTTTTTATGACGATAAGTCAAGCGCTATATCAAGATAAAGAATATATCATCTTTATCTTAGATACA
ATGTGTCAAATCTTTTTAGACATACTTCATTTACATATGAATCAAAAAGTGACCTATGAGTTTATGATGGAATCTTTATT
AGAGTATGTAAAGCGTATTAAATCAGATACAGCACAACGTGTTATTTTAAGATTACAAGATCAAATTAAAAATTTAAGAT
TACCAGTCAATATAAGTTTACAACTTACCTCATTAGCACTGGATTTAGAAAGTATTGTTCGAAATGGTTAA

Upstream 100 bases:

>100_bases
GCATTTCAGAAATGTTTAAAGAACGTATCGTCGTGATTGATGGTAATCAATCGATTGATGCAATCTATCAAATTATAATG
GATAACATATTAAAACGCCT

Downstream 100 bases:

>100_bases
AAGAGATTTGTTAGGTACTAAATTATATATTGAATCAGATATTGGTAAAGCATTTAATATGGATACCATTATTTTAAGTG
ACTTTGTAAGAGTTCCTAAA

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNKIVERFKYAIEKERLSHLYVISGSLGLTKQNLVKDIAYLIFKHHKDYPTLKHQLDSFNHPNLVYISGEGQSIKKDQIM
SLQQEFSKTSLVSGPRIFIIEQAETMSTQAANSLLKFLEEPKDDDTIGFLLVDDINLMLPTILSRAQIIRLTDTFDDSFI
QVLMEQEIDIKNAHFIASLTKELNEALAIFADQKYMDTVEFIDTFINWLNNPRTPLTPLFMTISQALYQDKEYIIFILDT
MCQIFLDILHLHMNQKVTYEFMMESLLEYVKRIKSDTAQRVILRLQDQIKNLRLPVNISLQLTSLALDLESIVRNG

Sequences:

>Translated_316_residues
MNKIVERFKYAIEKERLSHLYVISGSLGLTKQNLVKDIAYLIFKHHKDYPTLKHQLDSFNHPNLVYISGEGQSIKKDQIM
SLQQEFSKTSLVSGPRIFIIEQAETMSTQAANSLLKFLEEPKDDDTIGFLLVDDINLMLPTILSRAQIIRLTDTFDDSFI
QVLMEQEIDIKNAHFIASLTKELNEALAIFADQKYMDTVEFIDTFINWLNNPRTPLTPLFMTISQALYQDKEYIIFILDT
MCQIFLDILHLHMNQKVTYEFMMESLLEYVKRIKSDTAQRVILRLQDQIKNLRLPVNISLQLTSLALDLESIVRNG
>Mature_316_residues
MNKIVERFKYAIEKERLSHLYVISGSLGLTKQNLVKDIAYLIFKHHKDYPTLKHQLDSFNHPNLVYISGEGQSIKKDQIM
SLQQEFSKTSLVSGPRIFIIEQAETMSTQAANSLLKFLEEPKDDDTIGFLLVDDINLMLPTILSRAQIIRLTDTFDDSFI
QVLMEQEIDIKNAHFIASLTKELNEALAIFADQKYMDTVEFIDTFINWLNNPRTPLTPLFMTISQALYQDKEYIIFILDT
MCQIFLDILHLHMNQKVTYEFMMESLLEYVKRIKSDTAQRVILRLQDQIKNLRLPVNISLQLTSLALDLESIVRNG

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:
GO:0003887: DNA polymerase III, delta prime subunit
GO:0016740: DNA polymerase III, delta prime subunit
GO:0016779: DNA polymerase III, delta prime subunit

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 36671; Mature: 36671

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIVERFKYAIEKERLSHLYVISGSLGLTKQNLVKDIAYLIFKHHKDYPTLKHQLDSFN
CCHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
HPNLVYISGEGQSIKKDQIMSLQQEFSKTSLVSGPRIFIIEQAETMSTQAANSLLKFLEE
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHC
PKDDDTIGFLLVDDINLMLPTILSRAQIIRLTDTFDDSFIQVLMEQEIDIKNAHFIASLT
CCCCCCEEEEEECCHHHHHHHHHCHHHEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHH
KELNEALAIFADQKYMDTVEFIDTFINWLNNPRTPLTPLFMTISQALYQDKEYIIFILDT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHH
MCQIFLDILHLHMNQKVTYEFMMESLLEYVKRIKSDTAQRVILRLQDQIKNLRLPVNISL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
QLTSLALDLESIVRNG
EHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKIVERFKYAIEKERLSHLYVISGSLGLTKQNLVKDIAYLIFKHHKDYPTLKHQLDSFN
CCHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
HPNLVYISGEGQSIKKDQIMSLQQEFSKTSLVSGPRIFIIEQAETMSTQAANSLLKFLEE
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHC
PKDDDTIGFLLVDDINLMLPTILSRAQIIRLTDTFDDSFIQVLMEQEIDIKNAHFIASLT
CCCCCCEEEEEECCHHHHHHHHHCHHHEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHH
KELNEALAIFADQKYMDTVEFIDTFINWLNNPRTPLTPLFMTISQALYQDKEYIIFILDT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHH
MCQIFLDILHLHMNQKVTYEFMMESLLEYVKRIKSDTAQRVILRLQDQIKNLRLPVNISL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
QLTSLALDLESIVRNG
EHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]