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The map label for this gene is tdk [H]

Identifier: 162446944

GI number: 162446944

Start: 66334

End: 66927

Strand: Direct

Name: tdk [H]

Synonym: ACL_0058

Alternate gene names: 162446944

Gene position: 66334-66927 (Clockwise)

Preceding gene: 162446943

Following gene: 162446945

Centisome position: 4.43

GC content: 37.37

Gene sequence:

>594_bases
ATGTATCATACATACCGTAATGGTTTCATTGAAGTAGTTTGCGGACCGATGTTTGCAGGTAAAACTGAAGAACTTATAAG
ACGTGCAAAACGACTTAAATATGCTAAGCAAAACTATTTAGTGTTTAAACCAGTCATTGATAATAGATATAGCAGTAAAG
CAGAGATTGTATCGCACAGTTTATTAACGGAAAATGCCATATTAATAGAAAAGTCTAAAGACATTCTTGAACATATGAAT
GATTCTATTGAAGCTGTAATCATTGATGAAGCACAATTCTTTGATCAAGATATTGTTGAAATTGCTGATAGACTCGCAGA
CAGTGGTGTGCGTGTAATTATCGGTGGTTTAGATAGAGATTTTAAGGGGGAACCCTTTGGTCCAATGCCACAACTTTTAG
CGATTGCAGAGTTTGTTGTAAAACTCACCGCAATATGTCCTAAAACTGGTACACCAGCAACGCGTACACAACGCATCATT
AATGGTAAGCCAGCACGTATGGATGATCCACTGATTGTTGTAGGCGCATCTGACTCTTATGAGCCAAGATCTAGACATGC
CCACGAAGTACCAGGAAAATATGATAAAAAATAG

Upstream 100 bases:

>100_bases
TAAATTTAACAAGCGTTTAGAAAAAGCTAAAAAAGAATAATCATTACAGCGAGATTGCATCTCGCTTTTTGTTATAATAG
GATTAAGTGGGGTAAAAAAC

Downstream 100 bases:

>100_bases
TCGTGAGTACTTCATGAATGAGGCTCTAAAAGAAGCTAAAAAAGCTAATGATAAAGACGAGGTTCCTGTTGGTGCAGTTG
TCGTATTAGACGGTAAAATT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MYHTYRNGFIEVVCGPMFAGKTEELIRRAKRLKYAKQNYLVFKPVIDNRYSSKAEIVSHSLLTENAILIEKSKDILEHMN
DSIEAVIIDEAQFFDQDIVEIADRLADSGVRVIIGGLDRDFKGEPFGPMPQLLAIAEFVVKLTAICPKTGTPATRTQRII
NGKPARMDDPLIVVGASDSYEPRSRHAHEVPGKYDKK

Sequences:

>Translated_197_residues
MYHTYRNGFIEVVCGPMFAGKTEELIRRAKRLKYAKQNYLVFKPVIDNRYSSKAEIVSHSLLTENAILIEKSKDILEHMN
DSIEAVIIDEAQFFDQDIVEIADRLADSGVRVIIGGLDRDFKGEPFGPMPQLLAIAEFVVKLTAICPKTGTPATRTQRII
NGKPARMDDPLIVVGASDSYEPRSRHAHEVPGKYDKK
>Mature_197_residues
MYHTYRNGFIEVVCGPMFAGKTEELIRRAKRLKYAKQNYLVFKPVIDNRYSSKAEIVSHSLLTENAILIEKSKDILEHMN
DSIEAVIIDEAQFFDQDIVEIADRLADSGVRVIIGGLDRDFKGEPFGPMPQLLAIAEFVVKLTAICPKTGTPATRTQRII
NGKPARMDDPLIVVGASDSYEPRSRHAHEVPGKYDKK

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:
GO:0000166: Thymidine kinase
GO:0004797: Thymidine kinase
GO:0005524: Thymidine kinase
GO:0005737: Thymidine kinase
GO:0006259: Thymidine kinase
GO:0006260: Thymidine kinase
GO:0016301: Thymidine kinase
GO:0016310: Thymidine kinase
GO:0016740: Thymidine kinase

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=181, Percent_Identity=36.4640883977901, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17543396, Length=186, Percent_Identity=32.258064516129, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 22162; Mature: 22162

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYHTYRNGFIEVVCGPMFAGKTEELIRRAKRLKYAKQNYLVFKPVIDNRYSSKAEIVSHS
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHH
LLTENAILIEKSKDILEHMNDSIEAVIIDEAQFFDQDIVEIADRLADSGVRVIIGGLDRD
HHHCCEEEEECCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
FKGEPFGPMPQLLAIAEFVVKLTAICPKTGTPATRTQRIINGKPARMDDPLIVVGASDSY
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCC
EPRSRHAHEVPGKYDKK
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MYHTYRNGFIEVVCGPMFAGKTEELIRRAKRLKYAKQNYLVFKPVIDNRYSSKAEIVSHS
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHH
LLTENAILIEKSKDILEHMNDSIEAVIIDEAQFFDQDIVEIADRLADSGVRVIIGGLDRD
HHHCCEEEEECCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
FKGEPFGPMPQLLAIAEFVVKLTAICPKTGTPATRTQRIINGKPARMDDPLIVVGASDSY
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCC
EPRSRHAHEVPGKYDKK
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA