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The map label for this gene is tadA [H]

Identifier: 162446945

GI number: 162446945

Start: 66914

End: 67354

Strand: Direct

Name: tadA [H]

Synonym: ACL_0059

Alternate gene names: 162446945

Gene position: 66914-67354 (Clockwise)

Preceding gene: 162446944

Following gene: 162446946

Centisome position: 4.47

GC content: 36.73

Gene sequence:

>441_bases
ATGATAAAAAATAGTCGTGAGTACTTCATGAATGAGGCTCTAAAAGAAGCTAAAAAAGCTAATGATAAAGACGAGGTTCC
TGTTGGTGCAGTTGTCGTATTAGACGGTAAAATTATTGCAAGAGCACATAATTTGCGTGAAAGTAGACAATCCATCCATG
CTCATGCTGAATTTTTAGCAATAGAAAAAGCAGCAAAAAAAATTGGTAGTTGGCGTTTAGAAAATGCAGATGTATACGTT
ACATTAGAGCCTTGCCCAATGTGTGCAGGTGCAATGATACAAGCGCGTATTAAGAATTTGTATTACGGCGCGAAAGACCC
AAAGACTGGTGCAGTTGAAAGTGTTATAAAACTGCTTGACAATCCCTTTAATCATAAGATATACTATGAAGGTGGATTGT
TGATGGATAAGTGTTCAAACATCCCTTTCGACATTCTTTAA

Upstream 100 bases:

>100_bases
AATGGTAAGCCAGCACGTATGGATGATCCACTGATTGTTGTAGGCGCATCTGACTCTTATGAGCCAAGATCTAGACATGC
CCACGAAGTACCAGGAAAAT

Downstream 100 bases:

>100_bases
AAATAAGCGAAAATAAAAGAGTAAACATCCCTATAGGGTATTCTCATTCAATATTAAGGATCGAACCTGGTCAGGCCTTG
ATTGGAGCAGCCATAAGATA

Product: Zn dependent nucleoside deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MIKNSREYFMNEALKEAKKANDKDEVPVGAVVVLDGKIIARAHNLRESRQSIHAHAEFLAIEKAAKKIGSWRLENADVYV
TLEPCPMCAGAMIQARIKNLYYGAKDPKTGAVESVIKLLDNPFNHKIYYEGGLLMDKCSNIPFDIL

Sequences:

>Translated_146_residues
MIKNSREYFMNEALKEAKKANDKDEVPVGAVVVLDGKIIARAHNLRESRQSIHAHAEFLAIEKAAKKIGSWRLENADVYV
TLEPCPMCAGAMIQARIKNLYYGAKDPKTGAVESVIKLLDNPFNHKIYYEGGLLMDKCSNIPFDIL
>Mature_146_residues
MIKNSREYFMNEALKEAKKANDKDEVPVGAVVVLDGKIIARAHNLRESRQSIHAHAEFLAIEKAAKKIGSWRLENADVYV
TLEPCPMCAGAMIQARIKNLYYGAKDPKTGAVESVIKLLDNPFNHKIYYEGGLLMDKCSNIPFDIL

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=118, Percent_Identity=32.2033898305085, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI145693172, Length=146, Percent_Identity=42.4657534246575, Blast_Score=124, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=42.2680412371134, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17541138, Length=110, Percent_Identity=40, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17555996, Length=97, Percent_Identity=40.2061855670103, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21355527, Length=135, Percent_Identity=34.0740740740741, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16350; Mature: 16350

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKNSREYFMNEALKEAKKANDKDEVPVGAVVVLDGKIIARAHNLRESRQSIHAHAEFLA
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IEKAAKKIGSWRLENADVYVTLEPCPMCAGAMIQARIKNLYYGAKDPKTGAVESVIKLLD
HHHHHHHHCCEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
NPFNHKIYYEGGLLMDKCSNIPFDIL
CCCCCEEEECCCEEEHHHCCCCCCCC
>Mature Secondary Structure
MIKNSREYFMNEALKEAKKANDKDEVPVGAVVVLDGKIIARAHNLRESRQSIHAHAEFLA
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IEKAAKKIGSWRLENADVYVTLEPCPMCAGAMIQARIKNLYYGAKDPKTGAVESVIKLLD
HHHHHHHHCCEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
NPFNHKIYYEGGLLMDKCSNIPFDIL
CCCCCEEEECCCEEEHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]