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The map label for this gene is cssR [H]

Identifier: 162446897

GI number: 162446897

Start: 14659

End: 15309

Strand: Direct

Name: cssR [H]

Synonym: ACL_0010

Alternate gene names: 162446897

Gene position: 14659-15309 (Clockwise)

Preceding gene: 162446896

Following gene: 162446898

Centisome position: 0.98

GC content: 30.26

Gene sequence:

>651_bases
ATGAAAATATATTTTGTTGAAGACGAAGTTAATATTTCAGAAATTATCCGTAAATACTTAACGAGAGAAAATTATGATGT
TACAGTTTTCTATGATGGTGAAACAGCCATGGAACACGTTGGTGATCCAGTTGATTTATGGATTTTAGATATTATGTTGA
CTGGTGAAATTGACGGTTTTGATTTAATTAAGGCAATTTCAAAAGCAAATCCAGAAGCTGCTGTTATATTTACTTCAGCT
AGAGATCAAGCTTTAGATAAAATCAAAGGTCTTGAATTAGGATCTGATGATTATATTGCTAAACCATATTCACCTAAAGA
ATTAATGCTTAGAGTCAAAGCTGTTTTAAAACGTAAGAATTCAAGACCAGGTCATATGACTTATAGTGACTATTCTATTC
AATTAGACTCTAGAGAAATTAGACAAGGTGATAAACTAATTGAACTGACTAATAAAGAGTTTGAAATGTTACTTGTATTC
TTAAAAAATAAACAAGAACCAATTGAAAGAAAACTTTTATTAGAAACTATATGGGGTAAAAACTATGTGGGTTCTGATAG
AGTTGTAGATGACTTACTACGTCGTCTGCGTTCTAAAATGCCACTATTAAGAATAGAAACTATTTACGGATTCGGCTATA
GATTATTATGA

Upstream 100 bases:

>100_bases
CACCTTTAAAAAGGTGGCTTTTCCTTTATAAATACTAAGTTTCAAATTATGTGATAAAATTATATTAAGAAATTAATTAA
TCCAAGGGGGAATACAATTA

Downstream 100 bases:

>100_bases
CCAAACTAAAACTTGCCACACAACTCAATATCATATTTTCATTTGTCACGATATTAGGTGGTATGTTTTTTTTGTTTATC
GTTAGTTTGAGTTTTACAAG

Product: two-component response transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKIYFVEDEVNISEIIRKYLTRENYDVTVFYDGETAMEHVGDPVDLWILDIMLTGEIDGFDLIKAISKANPEAAVIFTSA
RDQALDKIKGLELGSDDYIAKPYSPKELMLRVKAVLKRKNSRPGHMTYSDYSIQLDSREIRQGDKLIELTNKEFEMLLVF
LKNKQEPIERKLLLETIWGKNYVGSDRVVDDLLRRLRSKMPLLRIETIYGFGYRLL

Sequences:

>Translated_216_residues
MKIYFVEDEVNISEIIRKYLTRENYDVTVFYDGETAMEHVGDPVDLWILDIMLTGEIDGFDLIKAISKANPEAAVIFTSA
RDQALDKIKGLELGSDDYIAKPYSPKELMLRVKAVLKRKNSRPGHMTYSDYSIQLDSREIRQGDKLIELTNKEFEMLLVF
LKNKQEPIERKLLLETIWGKNYVGSDRVVDDLLRRLRSKMPLLRIETIYGFGYRLL
>Mature_216_residues
MKIYFVEDEVNISEIIRKYLTRENYDVTVFYDGETAMEHVGDPVDLWILDIMLTGEIDGFDLIKAISKANPEAAVIFTSA
RDQALDKIKGLELGSDDYIAKPYSPKELMLRVKAVLKRKNSRPGHMTYSDYSIQLDSREIRQGDKLIELTNKEFEMLLVF
LKNKQEPIERKLLLETIWGKNYVGSDRVVDDLLRRLRSKMPLLRIETIYGFGYRLL

Specific function: Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=31.8777292576419, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=33.4821428571429, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=32.7354260089686, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=32.8828828828829, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=32.579185520362, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=31.5315315315315, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787229, Length=222, Percent_Identity=32.8828828828829, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=30.9734513274336, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1789402, Length=217, Percent_Identity=27.6497695852535, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=29.5454545454545, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=31.1688311688312, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=30.7017543859649, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=24.6575342465753, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=27.7056277056277, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25132; Mature: 25132

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYFVEDEVNISEIIRKYLTRENYDVTVFYDGETAMEHVGDPVDLWILDIMLTGEIDGF
CEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCHHEEEEEEEEECCCCCH
DLIKAISKANPEAAVIFTSARDQALDKIKGLELGSDDYIAKPYSPKELMLRVKAVLKRKN
HHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHCC
SRPGHMTYSDYSIQLDSREIRQGDKLIELTNKEFEMLLVFLKNKQEPIERKLLLETIWGK
CCCCCEEECCEEEEECCHHHHCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC
NYVGSDRVVDDLLRRLRSKMPLLRIETIYGFGYRLL
CCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCEECC
>Mature Secondary Structure
MKIYFVEDEVNISEIIRKYLTRENYDVTVFYDGETAMEHVGDPVDLWILDIMLTGEIDGF
CEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCHHEEEEEEEEECCCCCH
DLIKAISKANPEAAVIFTSARDQALDKIKGLELGSDDYIAKPYSPKELMLRVKAVLKRKN
HHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHCC
SRPGHMTYSDYSIQLDSREIRQGDKLIELTNKEFEMLLVFLKNKQEPIERKLLLETIWGK
CCCCCEEECCEEEEECCHHHHCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC
NYVGSDRVVDDLLRRLRSKMPLLRIETIYGFGYRLL
CCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9639930; 9384377; 11555295 [H]