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The map label for this gene is cssS [H]

Identifier: 162446898

GI number: 162446898

Start: 15306

End: 16622

Strand: Direct

Name: cssS [H]

Synonym: ACL_0011

Alternate gene names: 162446898

Gene position: 15306-16622 (Clockwise)

Preceding gene: 162446897

Following gene: 162446900

Centisome position: 1.02

GC content: 30.52

Gene sequence:

>1317_bases
ATGACCAAACTAAAACTTGCCACACAACTCAATATCATATTTTCATTTGTCACGATATTAGGTGGTATGTTTTTTTTGTT
TATCGTTAGTTTGAGTTTTACAAGAGCCTATGAAAATCAAAATAGAATTTATTTAGATAGTTATTTTAATGAGATTTTGA
GAATATATGAAGAAAATCCTATGGGTTTTTCTTATGAGAGTCTTACAAAATATAATGATTTTTTCATTATTGTAGACGAT
CAAGTAGTCCACTATTCAAAAAATAACGTATCACTACAAGATTTTAATCAAATATCTAATTTCATGCTAAGGGAACACTT
TAAGAGTCAAGAAACATATACCAACAGAACACTTAGATATACCATAGATGGCAACATAGCCTATATGGGACGAGTTAAAA
GACCATTGAATGGTACCAAGTATGGTGTATTTGCAGTATCTAACGTGACTGAGTTTGTTGAAGATATGACAGGTAATATC
CCGTTTTATACAACACTCGCATTCTTAAATATATTAGTCCTAGGTAACATCATTGTATGGCTATGGAGTACTAGTACAGT
AGGAAAATTAAAGGATCTACAATCTAGTGTGAAACAAATGATTGAAGATGATTATCAATCAGAGGTGAAAGTAGATAGTA
GTGCAGAAGAGATTGCTTCTCTTGCTGAAACTATTAATAATATGCGTATTGAAATTAAAAATAATGAAGATACTAAAAAA
GAAATGATTCAAAACTTAGGTCATGATTTGAAAACGCCGATTGCTGTCATTAGGTCTTATGCAGAAGCGATTCAAGATGG
TATTGAAGGTGTGGAATCGACTGATCTTATTATTAAACAATCAGATTTACTCAATAAAAAGGTTAAGCAAATTATTGAGT
ATAGTAAGATTGGCTATATTGATAACCATAATACTTATGAAAAGACATCATTTAAGACAATTGTTGAACAAGTTGTAAAT
AACTATAAATATATTACTAATTTAAGGTTTATTATTGATATTGAAACAGATTGGATTCATCTCATGGATCCAGAGGGGGC
CCATATTGCAATATCTAACATTGTAGATAATGCAGTGCGCTATGCACAAACAAAAATCGTTATCCAAATAACAGAAAAAA
AGCTCACCATCTTTAATGATGGAGAGCATATAGAAGAAAATGTTTTACCAAAGATTTTTAAAGCCTATGAAAAAGGTAGT
AAAGGTCAATTTGGTTTAGGTCTAGCCATTGTGAAAGAAACAATGGATAGATTTGGATTAAAGGTTTCTGTTATCAATCA
CGCTAATGGTGTATTATTTACGATAGAGCTGCAATAA

Upstream 100 bases:

>100_bases
TGGGTTCTGATAGAGTTGTAGATGACTTACTACGTCGTCTGCGTTCTAAAATGCCACTATTAAGAATAGAAACTATTTAC
GGATTCGGCTATAGATTATT

Downstream 100 bases:

>100_bases
TCATTGCTGCTCTATTTTTATAATCATCAGCAGTGATTATTTTTGAAGTATCGTTGAGTTTAATTGTAATCTCTTCTTTA
TCATATCGTGGGATAATATG

Product: two-component sensory histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MTKLKLATQLNIIFSFVTILGGMFFLFIVSLSFTRAYENQNRIYLDSYFNEILRIYEENPMGFSYESLTKYNDFFIIVDD
QVVHYSKNNVSLQDFNQISNFMLREHFKSQETYTNRTLRYTIDGNIAYMGRVKRPLNGTKYGVFAVSNVTEFVEDMTGNI
PFYTTLAFLNILVLGNIIVWLWSTSTVGKLKDLQSSVKQMIEDDYQSEVKVDSSAEEIASLAETINNMRIEIKNNEDTKK
EMIQNLGHDLKTPIAVIRSYAEAIQDGIEGVESTDLIIKQSDLLNKKVKQIIEYSKIGYIDNHNTYEKTSFKTIVEQVVN
NYKYITNLRFIIDIETDWIHLMDPEGAHIAISNIVDNAVRYAQTKIVIQITEKKLTIFNDGEHIEENVLPKIFKAYEKGS
KGQFGLGLAIVKETMDRFGLKVSVINHANGVLFTIELQ

Sequences:

>Translated_438_residues
MTKLKLATQLNIIFSFVTILGGMFFLFIVSLSFTRAYENQNRIYLDSYFNEILRIYEENPMGFSYESLTKYNDFFIIVDD
QVVHYSKNNVSLQDFNQISNFMLREHFKSQETYTNRTLRYTIDGNIAYMGRVKRPLNGTKYGVFAVSNVTEFVEDMTGNI
PFYTTLAFLNILVLGNIIVWLWSTSTVGKLKDLQSSVKQMIEDDYQSEVKVDSSAEEIASLAETINNMRIEIKNNEDTKK
EMIQNLGHDLKTPIAVIRSYAEAIQDGIEGVESTDLIIKQSDLLNKKVKQIIEYSKIGYIDNHNTYEKTSFKTIVEQVVN
NYKYITNLRFIIDIETDWIHLMDPEGAHIAISNIVDNAVRYAQTKIVIQITEKKLTIFNDGEHIEENVLPKIFKAYEKGS
KGQFGLGLAIVKETMDRFGLKVSVINHANGVLFTIELQ
>Mature_437_residues
TKLKLATQLNIIFSFVTILGGMFFLFIVSLSFTRAYENQNRIYLDSYFNEILRIYEENPMGFSYESLTKYNDFFIIVDDQ
VVHYSKNNVSLQDFNQISNFMLREHFKSQETYTNRTLRYTIDGNIAYMGRVKRPLNGTKYGVFAVSNVTEFVEDMTGNIP
FYTTLAFLNILVLGNIIVWLWSTSTVGKLKDLQSSVKQMIEDDYQSEVKVDSSAEEIASLAETINNMRIEIKNNEDTKKE
MIQNLGHDLKTPIAVIRSYAEAIQDGIEGVESTDLIIKQSDLLNKKVKQIIEYSKIGYIDNHNTYEKTSFKTIVEQVVNN
YKYITNLRFIIDIETDWIHLMDPEGAHIAISNIVDNAVRYAQTKIVIQITEKKLTIFNDGEHIEENVLPKIFKAYEKGSK
GQFGLGLAIVKETMDRFGLKVSVINHANGVLFTIELQ

Specific function: Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. Required for the transcription of htrA. Could detect misfolded proteins at the membrane-cell wall interface and then activate CssR by ph

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50366; Mature: 50235

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLKLATQLNIIFSFVTILGGMFFLFIVSLSFTRAYENQNRIYLDSYFNEILRIYEENP
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCC
MGFSYESLTKYNDFFIIVDDQVVHYSKNNVSLQDFNQISNFMLREHFKSQETYTNRTLRY
CCCCHHHHHCCCCEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCEEEE
TIDGNIAYMGRVKRPLNGTKYGVFAVSNVTEFVEDMTGNIPFYTTLAFLNILVLGNIIVW
EECCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEE
LWSTSTVGKLKDLQSSVKQMIEDDYQSEVKVDSSAEEIASLAETINNMRIEIKNNEDTKK
EECCCCHHHHHHHHHHHHHHHHHCHHHHEECCCCHHHHHHHHHHHCCEEEEEECCCCHHH
EMIQNLGHDLKTPIAVIRSYAEAIQDGIEGVESTDLIIKQSDLLNKKVKQIIEYSKIGYI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCC
DNHNTYEKTSFKTIVEQVVNNYKYITNLRFIIDIETDWIHLMDPEGAHIAISNIVDNAVR
CCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCEEEEECCCCCEEEHHHHHHHHHH
YAQTKIVIQITEKKLTIFNDGEHIEENVLPKIFKAYEKGSKGQFGLGLAIVKETMDRFGL
HHHEEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
KVSVINHANGVLFTIELQ
EEEEEECCCCEEEEEEEC
>Mature Secondary Structure 
TKLKLATQLNIIFSFVTILGGMFFLFIVSLSFTRAYENQNRIYLDSYFNEILRIYEENP
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCC
MGFSYESLTKYNDFFIIVDDQVVHYSKNNVSLQDFNQISNFMLREHFKSQETYTNRTLRY
CCCCHHHHHCCCCEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCEEEE
TIDGNIAYMGRVKRPLNGTKYGVFAVSNVTEFVEDMTGNIPFYTTLAFLNILVLGNIIVW
EECCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEE
LWSTSTVGKLKDLQSSVKQMIEDDYQSEVKVDSSAEEIASLAETINNMRIEIKNNEDTKK
EECCCCHHHHHHHHHHHHHHHHHCHHHHEECCCCHHHHHHHHHHHCCEEEEEECCCCHHH
EMIQNLGHDLKTPIAVIRSYAEAIQDGIEGVESTDLIIKQSDLLNKKVKQIIEYSKIGYI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCC
DNHNTYEKTSFKTIVEQVVNNYKYITNLRFIIDIETDWIHLMDPEGAHIAISNIVDNAVR
CCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCEEEEECCCCCEEEHHHHHHHHHH
YAQTKIVIQITEKKLTIFNDGEHIEENVLPKIFKAYEKGSKGQFGLGLAIVKETMDRFGL
HHHEEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
KVSVINHANGVLFTIELQ
EEEEEECCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353931; 9639930; 9384377; 11555295 [H]