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The map label for this gene is zraS [C]

Identifier: 162149056

GI number: 162149056

Start: 3377924

End: 3379789

Strand: Reverse

Name: zraS [C]

Synonym: GDI_3286

Alternate gene names: 162149056

Gene position: 3379789-3377924 (Counterclockwise)

Preceding gene: 162149057

Following gene: 162149055

Centisome position: 85.69

GC content: 70.9

Gene sequence:

>1866_bases
GTGGCGCTGGCCGACCTGCTGGAAGATTCGTTCACCATCCTGTCCACCACCTCGCCGGTCGAGGCGCTGGAAATCCTGGC
CGGGCGCAGCGACGTCGACGTCATCGTGTCCGACCAGCGCATGCCGGAAATGGGCGGTGACGTCATGCTGGCGCGGGCGC
GCACCGTCTGCGACGCGCAGGCGATCCTGCTGACCGGCTATGCCGATATCGGCGCGGTGGCGGCGGCGCTGAACCAGGGG
CGCATCTCGTTCTATTCCCACAAGCCGTGGGACGGCGACGCGCTGCGCGCCATGATCGTCCAGGCGGCGCATCGCCATCG
GCTGGAAGGCGAACTGCAGACCGAGCGGATGCTGCTGCGGGGGTTGCAGCAGAATCTGCGCGCGGGCCTGGCGTTCAAGG
ACCCGCAGGGGCGCTTCATCCGCATCAACCGCAAGGCGGCCGCCTTCTACGGGCGCGACGAGGCCGCCTGCCTGGGACAG
CGGGAGGAGGATGTGTGCGACCCCGCCCAGCGTCCCGCCGTCCGTGAGGCCGAGGCCCGCCTGGCGGCCGAGGGCAAGGA
CGAGGAGGTGATCGCCATTCCCGCGCCGGGAGGCGGGCTGTCCTGGCGGGAATTCACCCGGGTGCAACTGGACCGCAATG
CGCGCGGCGAGGCGTATTCCGTGCTGATCAACCGCGACATCACCCGCCAGAGGGAGATGGAGGCCCGGCTGCGCCAGGCG
GAGAAGATGCAGGCGCTGGGCACCATGGCCGGCGGGATCGCGCATGATTTCAACAATCTGCTGACGGCGGTGATGGGCTC
GCTGGAACTGGCCACGGACATGGCCGACGGGCTGGACGAACGGACGGCGCACCTGCTGGACAACGCGATGGCGGCGGCGC
GGCGCGGGGCGGAACTGACGCGGCGCCTGCTGAATTTCAGCCGGCCGCGCGACCTGAGCCTGCAGCCGGTGGACGTGAAC
GCGCTGCTGCGCGGCATGCGCGATCTGCTGATGCAGGGCGTGACCTCGCGCCGGCGCGACGGCAGCCATGCGTCGTTCGA
CATCCGCATGGACAAACTGGCGCCGGACGGCGACCTGCCGCCGGCGCGCACCGATGCCGGGCAACTGGAACTGGCGCTTC
TGAACCTGTGCATCAATGCCAGCGACGCCATGCCCGACGGCGGGACCATCACCCTGTCCACGCGGGTGGCGCACCTGGAC
GAACCGGCGGCCGAGGGCGAGCCCGCTTCGGGCGATTACGTCGTGGTGTCGGTGGCCGACCAGGGCACCGGCATGCCGCC
CGAAACGGTGGCGCGGGTGTTCGAACCGTTCTTCACCACCAAGGACGTGGGACGCGGGACGGGGCTGGGGCTGTCGATGA
TCTACGGCTTCGTGCGGCATGTCGGCGGCGATGTCCGCGTGACCAGCGCGCCGGGGCAGGGCACGCGGGTGGATCTGTAT
TTCCCGGTCCATCATCGCCAGGGCGGCGCATCCGACCCCCGCGAGGCGGCGGAGCACGCGGCGGCCCCGCACGGGCTGCG
GGTCCTGGTGGTCGATGACGAGGACGCGGTGCGGGCCGTGACCGCCGGCTTCCTGCGCGGAATGGGCCACCAGGCGATCG
AGGCCCGGGGCGGCGAGGACGCCCTGGCGCGGATCGCCGGCATGGCGCCCGATGTCCCCGACCTGGTGGTCATGGACGTG
ATGATGCCCCGGATGGACGGCGAGGAAGCGGCGCGCCGGATTCGCGCGCATTATCCGGGCAGCCGCATCCTGTTCCTGAC
CGGCTATGCCGACGACACCATCCTGCCCGACGACGCCCTGGTGCTGCGCAAGCCCTTCACCCAGGCGGACCTGTCCCGCC
ATGTCAGCCGCGCGATGGCGGGCTGA

Upstream 100 bases:

>100_bases
ATCTGGCGGCCATGGCCGATTCCACCGCCCTGCCGGCGGGAGAACACGCATGACCGATCGTCCCGTCGTCCTGCTGGTCG
ATGACGAACCGGAAATCCTG

Downstream 100 bases:

>100_bases
AGGGGCGAATCGAGGGGGCGAACCGGCGGGGGGCGGCCTTCCGTCTTTGGCTCTTGTCCTGCGGCGGGAACGGCCTATCT
CTGTCAGTCATGCAGAACAT

Product: two-component sensor histidine kinase/response regulator hybrid protein

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 621; Mature: 620

Protein sequence:

>621_residues
MALADLLEDSFTILSTTSPVEALEILAGRSDVDVIVSDQRMPEMGGDVMLARARTVCDAQAILLTGYADIGAVAAALNQG
RISFYSHKPWDGDALRAMIVQAAHRHRLEGELQTERMLLRGLQQNLRAGLAFKDPQGRFIRINRKAAAFYGRDEAACLGQ
REEDVCDPAQRPAVREAEARLAAEGKDEEVIAIPAPGGGLSWREFTRVQLDRNARGEAYSVLINRDITRQREMEARLRQA
EKMQALGTMAGGIAHDFNNLLTAVMGSLELATDMADGLDERTAHLLDNAMAAARRGAELTRRLLNFSRPRDLSLQPVDVN
ALLRGMRDLLMQGVTSRRRDGSHASFDIRMDKLAPDGDLPPARTDAGQLELALLNLCINASDAMPDGGTITLSTRVAHLD
EPAAEGEPASGDYVVVSVADQGTGMPPETVARVFEPFFTTKDVGRGTGLGLSMIYGFVRHVGGDVRVTSAPGQGTRVDLY
FPVHHRQGGASDPREAAEHAAAPHGLRVLVVDDEDAVRAVTAGFLRGMGHQAIEARGGEDALARIAGMAPDVPDLVVMDV
MMPRMDGEEAARRIRAHYPGSRILFLTGYADDTILPDDALVLRKPFTQADLSRHVSRAMAG

Sequences:

>Translated_621_residues
MALADLLEDSFTILSTTSPVEALEILAGRSDVDVIVSDQRMPEMGGDVMLARARTVCDAQAILLTGYADIGAVAAALNQG
RISFYSHKPWDGDALRAMIVQAAHRHRLEGELQTERMLLRGLQQNLRAGLAFKDPQGRFIRINRKAAAFYGRDEAACLGQ
REEDVCDPAQRPAVREAEARLAAEGKDEEVIAIPAPGGGLSWREFTRVQLDRNARGEAYSVLINRDITRQREMEARLRQA
EKMQALGTMAGGIAHDFNNLLTAVMGSLELATDMADGLDERTAHLLDNAMAAARRGAELTRRLLNFSRPRDLSLQPVDVN
ALLRGMRDLLMQGVTSRRRDGSHASFDIRMDKLAPDGDLPPARTDAGQLELALLNLCINASDAMPDGGTITLSTRVAHLD
EPAAEGEPASGDYVVVSVADQGTGMPPETVARVFEPFFTTKDVGRGTGLGLSMIYGFVRHVGGDVRVTSAPGQGTRVDLY
FPVHHRQGGASDPREAAEHAAAPHGLRVLVVDDEDAVRAVTAGFLRGMGHQAIEARGGEDALARIAGMAPDVPDLVVMDV
MMPRMDGEEAARRIRAHYPGSRILFLTGYADDTILPDDALVLRKPFTQADLSRHVSRAMAG
>Mature_620_residues
ALADLLEDSFTILSTTSPVEALEILAGRSDVDVIVSDQRMPEMGGDVMLARARTVCDAQAILLTGYADIGAVAAALNQGR
ISFYSHKPWDGDALRAMIVQAAHRHRLEGELQTERMLLRGLQQNLRAGLAFKDPQGRFIRINRKAAAFYGRDEAACLGQR
EEDVCDPAQRPAVREAEARLAAEGKDEEVIAIPAPGGGLSWREFTRVQLDRNARGEAYSVLINRDITRQREMEARLRQAE
KMQALGTMAGGIAHDFNNLLTAVMGSLELATDMADGLDERTAHLLDNAMAAARRGAELTRRLLNFSRPRDLSLQPVDVNA
LLRGMRDLLMQGVTSRRRDGSHASFDIRMDKLAPDGDLPPARTDAGQLELALLNLCINASDAMPDGGTITLSTRVAHLDE
PAAEGEPASGDYVVVSVADQGTGMPPETVARVFEPFFTTKDVGRGTGLGLSMIYGFVRHVGGDVRVTSAPGQGTRVDLYF
PVHHRQGGASDPREAAEHAAAPHGLRVLVVDDEDAVRAVTAGFLRGMGHQAIEARGGEDALARIAGMAPDVPDLVVMDVM
MPRMDGEEAARRIRAHYPGSRILFLTGYADDTILPDDALVLRKPFTQADLSRHVSRAMAG

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=267, Percent_Identity=32.5842696629214, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788549, Length=384, Percent_Identity=27.34375, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788713, Length=412, Percent_Identity=25.7281553398058, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081816, Length=184, Percent_Identity=29.8913043478261, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=496, Percent_Identity=23.1854838709677, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI145693157, Length=302, Percent_Identity=24.1721854304636, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67211; Mature: 67080

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALADLLEDSFTILSTTSPVEALEILAGRSDVDVIVSDQRMPEMGGDVMLARARTVCDAQ
CCHHHHHCCCEEEEECCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHCCC
AILLTGYADIGAVAAALNQGRISFYSHKPWDGDALRAMIVQAAHRHRLEGELQTERMLLR
EEEEECCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GLQQNLRAGLAFKDPQGRFIRINRKAAAFYGRDEAACLGQREEDVCDPAQRPAVREAEAR
HHHHHHHCCCEEECCCCCEEEEECHHHEECCCCHHHHCCCCCHHHCCHHCCCCHHHHHHH
LAAEGKDEEVIAIPAPGGGLSWREFTRVQLDRNARGEAYSVLINRDITRQREMEARLRQA
HHCCCCCCCEEEEECCCCCCCHHHHHHEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHH
EKMQALGTMAGGIAHDFNNLLTAVMGSLELATDMADGLDERTAHLLDNAMAAARRGAELT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHH
RRLLNFSRPRDLSLQPVDVNALLRGMRDLLMQGVTSRRRDGSHASFDIRMDKLAPDGDLP
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
PARTDAGQLELALLNLCINASDAMPDGGTITLSTRVAHLDEPAAEGEPASGDYVVVSVAD
CCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEC
QGTGMPPETVARVFEPFFTTKDVGRGTGLGLSMIYGFVRHVGGDVRVTSAPGQGTRVDLY
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEE
FPVHHRQGGASDPREAAEHAAAPHGLRVLVVDDEDAVRAVTAGFLRGMGHQAIEARGGED
EEEECCCCCCCCHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHCCCCHH
ALARIAGMAPDVPDLVVMDVMMPRMDGEEAARRIRAHYPGSRILFLTGYADDTILPDDAL
HHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCC
VLRKPFTQADLSRHVSRAMAG
EEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALADLLEDSFTILSTTSPVEALEILAGRSDVDVIVSDQRMPEMGGDVMLARARTVCDAQ
CHHHHHCCCEEEEECCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHCCC
AILLTGYADIGAVAAALNQGRISFYSHKPWDGDALRAMIVQAAHRHRLEGELQTERMLLR
EEEEECCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GLQQNLRAGLAFKDPQGRFIRINRKAAAFYGRDEAACLGQREEDVCDPAQRPAVREAEAR
HHHHHHHCCCEEECCCCCEEEEECHHHEECCCCHHHHCCCCCHHHCCHHCCCCHHHHHHH
LAAEGKDEEVIAIPAPGGGLSWREFTRVQLDRNARGEAYSVLINRDITRQREMEARLRQA
HHCCCCCCCEEEEECCCCCCCHHHHHHEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHH
EKMQALGTMAGGIAHDFNNLLTAVMGSLELATDMADGLDERTAHLLDNAMAAARRGAELT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHH
RRLLNFSRPRDLSLQPVDVNALLRGMRDLLMQGVTSRRRDGSHASFDIRMDKLAPDGDLP
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
PARTDAGQLELALLNLCINASDAMPDGGTITLSTRVAHLDEPAAEGEPASGDYVVVSVAD
CCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEC
QGTGMPPETVARVFEPFFTTKDVGRGTGLGLSMIYGFVRHVGGDVRVTSAPGQGTRVDLY
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEE
FPVHHRQGGASDPREAAEHAAAPHGLRVLVVDDEDAVRAVTAGFLRGMGHQAIEARGGED
EEEECCCCCCCCHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHCCCCHH
ALARIAGMAPDVPDLVVMDVMMPRMDGEEAARRIRAHYPGSRILFLTGYADDTILPDDAL
HHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCC
VLRKPFTQADLSRHVSRAMAG
EEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA