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The map label for this gene is iorA [H]

Identifier: 162149050

GI number: 162149050

Start: 3371275

End: 3371748

Strand: Direct

Name: iorA [H]

Synonym: GDI_3280

Alternate gene names: 162149050

Gene position: 3371275-3371748 (Clockwise)

Preceding gene: 162149049

Following gene: 162149051

Centisome position: 85.48

GC content: 66.46

Gene sequence:

>474_bases
ATGACGACTTTTCGCCTCAACGGCCATGACGTGTCCGTCGACGTGCCGGATGACACCCCGCTGCTGTGGGTCATCCGCGA
TGAAATCGGACTGACCGGCACCAAGTTCGGCTGCGGCATCGGCATGTGCGGTGCCTGCACCGTCCATGTAGGCGGCCGCG
CCACCCGGTCCTGCATCACGCCGATCGTCGCCGTGCAGGGGGCGGACATCACGACCATCGAAGGGCTGGACCCGGCGGGC
GCCCATCCGCTGCAGGAGGCATGGAAGGACCTGCAGGTCCCGCAATGCGGCTACTGCCAGTCGGGACAGATCATGCAGGC
CGCGAGCCTGCTGCGCGACTACCCGAACCCGACGGACGAGGACATCGACGCGGTCATGGGCGGCTCGCTCTGCCGCTGCA
TGACCTATATCCGCATTCGCGACGCCATCAAGAAGGCCGCCCTGGCCATGCGGGAGGAACCGTCCAATGGGTAG

Upstream 100 bases:

>100_bases
CCCCTGGACCGACCTGGAGAAGAAGGCTGCCGCCGTACGCTCGACATTGCCCGCGCCACCGGTCGCGGCCTCTCATTGAG
ATGACAGACGGAGCCCCGAC

Downstream 100 bases:

>100_bases
GCTGAGCCAGATGGACAAGCGCGGCGGCGCGACGGGGCAGATGTCGCGCCGGGGCTTCCTGATGATCGCGGCGGGCGGCG
CGGGCGCCCTGTTCGGCTTC

Product: xanthine dehydrogenase iron-sulfur-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MTTFRLNGHDVSVDVPDDTPLLWVIRDEIGLTGTKFGCGIGMCGACTVHVGGRATRSCITPIVAVQGADITTIEGLDPAG
AHPLQEAWKDLQVPQCGYCQSGQIMQAASLLRDYPNPTDEDIDAVMGGSLCRCMTYIRIRDAIKKAALAMREEPSNG

Sequences:

>Translated_157_residues
MTTFRLNGHDVSVDVPDDTPLLWVIRDEIGLTGTKFGCGIGMCGACTVHVGGRATRSCITPIVAVQGADITTIEGLDPAG
AHPLQEAWKDLQVPQCGYCQSGQIMQAASLLRDYPNPTDEDIDAVMGGSLCRCMTYIRIRDAIKKAALAMREEPSNG
>Mature_156_residues
TTFRLNGHDVSVDVPDDTPLLWVIRDEIGLTGTKFGCGIGMCGACTVHVGGRATRSCITPIVAVQGADITTIEGLDPAGA
HPLQEAWKDLQVPQCGYCQSGQIMQAASLLRDYPNPTDEDIDAVMGGSLCRCMTYIRIRDAIKKAALAMREEPSNG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=146, Percent_Identity=37.6712328767123, Blast_Score=77, Evalue=5e-15,
Organism=Homo sapiens, GI71773480, Length=154, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786480, Length=161, Percent_Identity=40.9937888198758, Blast_Score=113, Evalue=7e-27,
Organism=Escherichia coli, GI1789232, Length=142, Percent_Identity=35.2112676056338, Blast_Score=77, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17539860, Length=152, Percent_Identity=36.1842105263158, Blast_Score=107, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17540638, Length=157, Percent_Identity=37.5796178343949, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32566215, Length=152, Percent_Identity=35.5263157894737, Blast_Score=102, Evalue=6e-23,
Organism=Drosophila melanogaster, GI17737937, Length=154, Percent_Identity=35.7142857142857, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24647201, Length=157, Percent_Identity=36.3057324840764, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24647197, Length=161, Percent_Identity=35.4037267080745, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647195, Length=161, Percent_Identity=35.4037267080745, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647193, Length=159, Percent_Identity=35.8490566037736, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24647199, Length=157, Percent_Identity=35.031847133758, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16795; Mature: 16664

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFRLNGHDVSVDVPDDTPLLWVIRDEIGLTGTKFGCGIGMCGACTVHVGGRATRSCIT
CCEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHH
PIVAVQGADITTIEGLDPAGAHPLQEAWKDLQVPQCGYCQSGQIMQAASLLRDYPNPTDE
HHEEECCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCH
DIDAVMGGSLCRCMTYIRIRDAIKKAALAMREEPSNG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTFRLNGHDVSVDVPDDTPLLWVIRDEIGLTGTKFGCGIGMCGACTVHVGGRATRSCIT
CEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHH
PIVAVQGADITTIEGLDPAGAHPLQEAWKDLQVPQCGYCQSGQIMQAASLLRDYPNPTDE
HHEEECCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCH
DIDAVMGGSLCRCMTYIRIRDAIKKAALAMREEPSNG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]