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The map label for this gene is cysH [H]

Identifier: 162149005

GI number: 162149005

Start: 3325326

End: 3325937

Strand: Direct

Name: cysH [H]

Synonym: GDI_3235

Alternate gene names: 162149005

Gene position: 3325326-3325937 (Clockwise)

Preceding gene: 162149003

Following gene: 162149006

Centisome position: 84.31

GC content: 71.24

Gene sequence:

>612_bases
GTGATGACCGGCGGGCTGCATGGCCGGGTCGGCATCGTGTCGTCTTTCGGCTCGGAATCGGCGGTGCTGCTGGCGCTGGC
GGCCGAGGTCGATCCCGCCATTCCGGTCCTGTTCCTGGAGACCGGGCAGCATTTCCCTGAAACCCTGGCCTATCGTGACC
GGCTGGCCGCCCGCCTGGGCCTGACCGACGTGCGCAGCATCCAGCCGCAGCCCCGGCAGATCCGCGAGCGCGACCCCGAC
GGGCAACTCTGGGCCTTCGATCCCGATGCCTGCTGCGCGCTGCGCAAGGTCGAGCCGCTGGACGAGGCGATCATTCCCTT
CGACGCCTGGATGACGGGCCGCAAGCGTTCGCAGGCCGCGACGCGCGCCCAGTTGCCGGTCGTCGAGGACGCCGCCGACG
GCCGCATCAAGATCAATCCCCTGGCGCGCTGGACGCCGGCCGAACTGGACGCGGAAATGACGCGCCGCAACCTGCCGCGC
CATCCGCTGGCCCTGCGGGGCTACAAGTCGATCGGCTGCGCCCCCTGCACCCGTCCGGTGGCGGAAGGCGAGGACCCGCG
CGCCGGACGCTGGGCCGGCCTGTCGAAGACCGAATGCGGCATCCACGTCTGA

Upstream 100 bases:

>100_bases
CGTGCATTGAGGGATGTGGATCTGAACCGTGCGCATAGACCCAGCGATCAGGCAATCCATCGAGACCGCCGGTGAGTCCG
CGCCGGCCATCCTGCGCGCC

Downstream 100 bases:

>100_bases
ACCCACCCCGTAGAGCCCGAAACCCTGTAAGGTAGCGCCCCCGTCATGGACGATCTCGACCAACTCGAAGCCCAGAGCGT
GTATATCCTGCGCGAAGCGT

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MMTGGLHGRVGIVSSFGSESAVLLALAAEVDPAIPVLFLETGQHFPETLAYRDRLAARLGLTDVRSIQPQPRQIRERDPD
GQLWAFDPDACCALRKVEPLDEAIIPFDAWMTGRKRSQAATRAQLPVVEDAADGRIKINPLARWTPAELDAEMTRRNLPR
HPLALRGYKSIGCAPCTRPVAEGEDPRAGRWAGLSKTECGIHV

Sequences:

>Translated_203_residues
MMTGGLHGRVGIVSSFGSESAVLLALAAEVDPAIPVLFLETGQHFPETLAYRDRLAARLGLTDVRSIQPQPRQIRERDPD
GQLWAFDPDACCALRKVEPLDEAIIPFDAWMTGRKRSQAATRAQLPVVEDAADGRIKINPLARWTPAELDAEMTRRNLPR
HPLALRGYKSIGCAPCTRPVAEGEDPRAGRWAGLSKTECGIHV
>Mature_203_residues
MMTGGLHGRVGIVSSFGSESAVLLALAAEVDPAIPVLFLETGQHFPETLAYRDRLAARLGLTDVRSIQPQPRQIRERDPD
GQLWAFDPDACCALRKVEPLDEAIIPFDAWMTGRKRSQAATRAQLPVVEDAADGRIKINPLARWTPAELDAEMTRRNLPR
HPLALRGYKSIGCAPCTRPVAEGEDPRAGRWAGLSKTECGIHV

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=203, Percent_Identity=32.0197044334975, Blast_Score=97, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6325425, Length=209, Percent_Identity=35.4066985645933, Blast_Score=127, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 22240; Mature: 22240

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTGGLHGRVGIVSSFGSESAVLLALAAEVDPAIPVLFLETGQHFPETLAYRDRLAARLG
CCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHC
LTDVRSIQPQPRQIRERDPDGQLWAFDPDACCALRKVEPLDEAIIPFDAWMTGRKRSQAA
CHHHHHCCCCCHHHHCCCCCCCEEEECHHHHHHHHHCCCCHHHHCCHHHHHCCCHHHHHH
TRAQLPVVEDAADGRIKINPLARWTPAELDAEMTRRNLPRHPLALRGYKSIGCAPCTRPV
HHHCCCCEECCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
AEGEDPRAGRWAGLSKTECGIHV
CCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMTGGLHGRVGIVSSFGSESAVLLALAAEVDPAIPVLFLETGQHFPETLAYRDRLAARLG
CCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHC
LTDVRSIQPQPRQIRERDPDGQLWAFDPDACCALRKVEPLDEAIIPFDAWMTGRKRSQAA
CHHHHHCCCCCHHHHCCCCCCCEEEECHHHHHHHHHCCCCHHHHCCHHHHHCCCHHHHHH
TRAQLPVVEDAADGRIKINPLARWTPAELDAEMTRRNLPRHPLALRGYKSIGCAPCTRPV
HHHCCCCEECCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
AEGEDPRAGRWAGLSKTECGIHV
CCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA